Edinburgh Research Explorer

Rachel Guest

Advanced Specialty Trainee in HPB & Transplant Surgery

  1. 2020
  2. TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression.

    Dwyer, B. J., Jarman, E. J., Gogoi-Tiwari, J., Ferreira-Gonzalez, S., Boulter, L., Guest, R. V., Kendall, T. J., Thekkedath Kurian, D., Kilpatrick, A. M., Robson, A. J., O'Duibhir, E., Man, T. Y., Campana, L., Starkey Lewis, P. J., Wigmore, S. J., Olynyk, J. K., Ramm, G. A., Tirnitz-Parker, J. E. E. & Forbes, S. J., 19 Nov 2020, In: Journal of Hepatology. n/a, p. 1-72

    Research output: Contribution to journalArticlepeer-review

  3. Meta-Analysis and Meta-Regression of Survival after Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma

    Cambridge, W. A., Fairfield, C., Powell, J., Harrison, E., Soreide, K., Wigmore, S. & Guest, R., 24 Feb 2020, In: Annals of Surgery.

    Research output: Contribution to journalArticlepeer-review

  4. 2019
  5. Modulation of biliary cancer chemo-resistance through microRNA-mediated rewiring of the expansion of CD133+ cells

    Carotenuto, P., Hedayat, S., Fassan, M., Cardinale, V., Lampis, A., Guzzardo, V., Vicentini, C., Scarpa, A., Cascione, L., Costantini, D., Carpino, G., Alvaro, D., Ghidini, M., Trevisani, F., Te Poele, R., Salati, M., Ventura, S., Vlachogiannis, G., Hahne, J. C., Boulter, L. & 16 others, Forbes, S. J., Guest, R., Cillo, U., Said-Huntingford, I., Begum, R., Smyth, E., Michalarea, V., Cunningham, D., Rimassa, L., Santoro, A., Roncalli, M., Kirnkin, V., Clarke, P., Workman, P., Valeri, N. & Braconi, C., 26 Dec 2019, In: Hepatology.

    Research output: Contribution to journalArticlepeer-review

  6. Systematic review of management of incidental gallbladder cancer after cholecystectomy

    Soreide, K., Guest, R. V., Harrison, E. M., Kendall, T. J., Garden, O. J. & Wigmore, S. J., Jan 2019, In: British Journal of Surgery.

    Research output: Contribution to journalArticlepeer-review

  7. 2017
  8. Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers

    Carotenuto, P., Fassan, M., Pandolfo, R., Lampis, A., Vicentini, C., Cascione, L., Paulus-Hock, V., Boulter, L., Guest, R., Quagliata, L., Hahne, J. C., Ridgway, R., Jamieson, T., Athineos, D., Veronese, A., Visone, R., Murgia, C., Ferrari, G., Guzzardo, V., Evans, T. R. J. & 12 others, MacLeod, M., Feng, G. J., Dale, T., Negrini, M., Forbes, S. J., Terracciano, L., Scarpa, A., Patel, T., Valeri, N., Workman, P., Sansom, O. & Braconi, C., Jul 2017, In: Gut.

    Research output: Contribution to journalArticlepeer-review

  9. Understanding liver regeneration to bring new insights to the mechanisms driving cholangiocarcinoma

    Guest, R., Boulter, L., Dwyer, B. & Forbes, S., 22 May 2017, In: npj Regenerative Medicine.

    Research output: Contribution to journalArticlepeer-review

  10. 2016
  11. Notch3 drives development and progression of cholangiocarcinoma

    Guest, R. V., Boulter, L., Dwyer, B. J., Kendall, T. J., Man, T., Minnis-Lyons, S. E., Lu, W-Y., Robson, A. J., Gonzalez, S. F., Raven, A., Wojtacha, D., Morton, J. P., Komuta, M., Roskams, T., Wigmore, S. J., Sansom, O. J. & Forbes, S. J., 25 Oct 2016, In: Proceedings of the National Academy of Sciences. 113, 43, p. 12250-12255 6 p.

    Research output: Contribution to journalArticlepeer-review

  12. 2015
  13. Hepatic progenitor cells of biliary origin with liver repopulation capacity

    Lu, W-Y., Bird, T. G., Boulter, L., Tsuchiya, A., Cole, A. M., Hay, T., Guest, R. V., Wojtacha, D., Man, T. Y., Mackinnon, A., Ridgway, R. A., Kendall, T., Williams, M. J., Jamieson, T., Raven, A., Hay, D. C., Iredale, J. P., Clarke, A. R., Sansom, O. J. & Forbes, S. J., Aug 2015, In: Nature Cell Biology. 17, 8, p. 971-983 13 p.

    Research output: Contribution to journalArticlepeer-review

  14. WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited

    Boulter, L., Guest, R. V., Kendall, T. J., Wilson, D. H., Wojtacha, D., Robson, A. J., Ridgway, R. A., Samuel, K., Van Rooijen, N., Barry, S. T., Wigmore, S. J., Sansom, O. J. & Forbes, S. J., 2 Mar 2015, In: Journal of Clinical Investigation. 125, 3, p. 1269–1285 17 p.

    Research output: Contribution to journalArticlepeer-review

  15. 2014
  16. Polysialic Acid/Neural Cell Adhesion Molecule Modulates the Formation of Ductular Reactions in Liver Injury

    Tsuchiya, A., Lu, W-Y., Weinhold, B., Boulter, L., Stutchfield, B. M., Williams, M. J., Guest, R. V., Minnis-Lyons, S. E., MacKinnon, A. C., Schwarzer, D., Ichida, T., Nomoto, M., Aoyagi, Y., Gerardy-Schahn, R. & Forbes, S. J., Nov 2014, In: Hepatology. 60, 5, p. 1727-1740 14 p.

    Research output: Contribution to journalArticlepeer-review

  17. Endogenous notch-driven tumorigenesis functions via notch3 to promote PI3k/AKT mediated cell survival in intrahepatic cholangiocarcinoma

    Guest, R. V., Boulter, L., Kendall, T., Lu, W. -Y., Robson, A., Komuta, M., McKinnon, A., Wotjacha, D., Minnis-Lyons, S. E., Walker, R., Lowell, S., Roskams, T., Wigmore, S., Sansom, O. & Forbes, S. J., May 2014, In: British Journal of Surgery. 101, p. 47-47 1 p.

    Research output: Contribution to journalMeeting abstract

  18. Govert Bidloo's liver: human symmetry reflected

    Guest, R. V., Margócsy, D. & Wigmore, S. J., 22 Feb 2014, In: The Lancet. 383, 9918, p. 688-9 2 p.

    Research output: Contribution to journalComment/debate

  19. Cell Lineage Tracing Reveals a Biliary Origin of Intrahepatic Cholangiocarcinoma

    Guest, R. V., Boulter, L., Kendall, T. J., Minnis-Lyons, S., Walker, R., Wigmore, S. J., Sansom, O. J. & Forbes, S. J., 15 Feb 2014, In: Cancer Research. 74, 4, p. 1005-1010 6 p.

    Research output: Contribution to journalArticlepeer-review

  20. 2013
  21. NOVEL METHOD TO ISOLATE AND EXPAND EPCAM+CD24+CD133+ADULT HEPATIC PROGENITOR CELLS WITH LIVER REPOPULATION CAPACITY

    Lu, W. Y., Tsuchiya, A., Boulter, L., Guest, R. V., Bird, T. G., Williams, M. J., Hay, D. C., Iredale, J. P. & Forbes, S. J., Apr 2013, In: Journal of Hepatology. 58, p. S14-S14 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  22. 2012
  23. NOTCH SIGNALLING WITHIN THE TUMOUR-STROMAL MICROENVIRONMENT DRIVES PROGRESSION OF CHOLANGIOCARCINOMA WHILST PATHWAY INHIBITION ENHANCES CHEMOSENSITIVITY

    Robson, A., Guest, R. V., Boulter, L., Pellicoro, A., Sansom, O. & Forbes, S., Apr 2012, In: Journal of Hepatology. 56, p. S15-S15 1 p.

    Research output: Contribution to journalMeeting abstract

  24. Application of variable life adjusted display (VLAD) to risk-adjusted mortality of esophagogastric cancer surgery

    Guest, R. V., Chandrabalan, V. V., Murray, G. D. & Auld, C. D., 1 Jan 2012, In: World Journal of Surgery. 36, 1, p. 104-108 5 p.

    Research output: Contribution to journalArticlepeer-review

  25. The role of notch signalling within the tumour-stromal microenvironment in cholangiocarcinoma

    Robson, A. J., Guest, R. V., Boulter, L., Iredale, J. P. & Forbes, S. J., 2012, In: British Journal of Surgery. 99, p. 3-3 1 p.

    Research output: Contribution to journalMeeting abstract

  26. 2010
  27. Application of variable life adjusted display (VLAD) to risk-adjusted mortality of oesophago-gastric cancer surgery

    Guest, R. V., Chandrabalan, V. V., Murray, G. D. & Auld, C. D., 2010, In: British Journal of Surgery. 97, p. 66-67 2 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  28. 2009
  29. Carotid endarterectomy: are we meeting the two week target?

    Guest, R. V., Richards, J. M. J., Fraser, S. C. A. & Chalmers, R. T. A., 2009, In: Scottish Medical Journal. 54, 2, p. 27-9 3 p.

    Research output: Contribution to journalArticlepeer-review