Edinburgh Research Explorer

Riccardo Marioni

Senior Research Fellow

  1. Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

    Hägg, S., Zhan, Y., Karlsson, R., Gerritsen, L., Ploner, A., Van Der Lee, S. J., Broer, L., Deelen, J., Marioni, R. E., Wong, A., Lundquist, A., Zhu, G., Hansell, N. K., Sillanpää, E., Fedko, I. O., Amin, N. A., Beekman, M., De Craen, A. J. M., Degerman, S., Harris, S. E. & 25 others, Kan, K., Martin-ruiz, C. M., Montgomery, G. W., Adolfsson, A. N., Reynolds, C. A., Samani, N. J., Suchiman, H. E. D., Viljanen, A., Von Zglinicki, T., Wright, M. J., Hottenga, J., Boomsma, D. I., Rantanen, T., Kaprio, J. A., Nyholt, D. R., Martin, N. G., Nyberg, L., Adolfsson, R., Kuh, D., Starr, J. M., Deary, I. J., Slagboom, P. E., Van Duijn, C. M., Codd, V. & Pedersen, N. L., 18 Apr 2017, In : Translational Psychiatry. 7, 4, p. e1100

    Research output: Contribution to journalArticle

  2. An epigenome-wide association study meta-analysis of educational attainment

    Karlsson Linnér, R., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davis, M., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S., Lahti, J., Mcrae, A. F., Mandaviya, P. R., Seppälä, I. & 50 others, Wang, Y., Baglietto, L., Binder, E. B., Harris, S., Hodge, M., Horvath, S., Hurme, M., Johannesson, M., Latvala, A., Mather, K. A., Medland, S. E., Metspalu, A., Milani, L., Milne, R. L., Pattie, A., Pedersen, N. L., Peters, A., Polidoro, S., Räikkönen, K., Severi, G., Starr, J. M., Stolk, L., Waldenberger, M., Eriksson, J. G., Esko, T., Franke, L., Gieger, C., Giles, G. G., Hägg, S., Jousilahti, P., Kaprio, J., Kähönen, M., Lehtimäki, T., Martin, N. G., Van Meurs, J. B. C., Ollikainen, M., Perola, M., Posthuma, D., Raitakari, O. T., Sachdev, P. S., Taskesen, E., Uitterlinden, A. G., Vineis, P., Wijmenga, C., Wright, M. J., Relton, C., Davey Smith, G., Deary, I. J., Koellinger, P. D. & Benjamin, D. J., 31 Oct 2017, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  3. New blood pressure–associated loci Identified in meta-analyses of 475 000 individuals

    Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-jensen, J., Brandslund, I., Farmaki, A., Fava, C., Ferreira, T., Herzig, K., Giri, A. & 121 others, Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Richard, M. A., Smith, J. A., Southam, L., Stančáková, A., Stirrups, K. E., Tragante, V., Tuomi, T., Tzoulaki, I., Varga, T. V., Weiss, S., Yiorkas, A. M., Young, R., Zhang, W., Barnes, M. R., Cabrera, C. P., Gao, H., Boehnke, M., Boerwinkle, E., Chambers, J. C., Connell, J. M., Christensen, C. K., De Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Dominiczak, A. F., Dörr, M., Joehanes, R., Edwards, T. L., Esko, T., Fornage, M., Franceschini, N., Franks, P. W., Gambaro, G., Groop, L., Hallmans, G., Hansen, T., Hayward, C., Heikki, O., Ingelsson, E., Tuomilehto, J., Jarvelin, M., Kardia, S. L. R., Karpe, F., Kooner, J. S., Lakka, T. A., Langenberg, C., Lind, L., Loos, R. J. F., Laakso, M., Mccarthy, M. I., Melander, O., Mohlke, K. L., Morris, A. P., Palmer, C. N. A., Pedersen, O., Polasek, O., Poulter, N. R., Province, M. A., Psaty, B. M., Ridker, P. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sever, P. J., Skaaby, T., Stafford, J. M., Starr, J. M., Van Der Harst, P., Van Der Meer, P., Van Duijn, C. M., Vergnaud, A., Gudnason, V., Wareham, N. J., Wilson, J. G., Willer, C. J., Witte, D. R., Zeggini, E., Saleheen, D., Butterworth, A. S., Danesh, J., Asselbergs, F. W., Wain, L. V., Ehret, G. B., Chasman, D. I., Caulfield, M. J., Elliott, P., Lindgren, C. M., Levy, D., Newton-cheh, C., Munroe, P. B. & Howson, J. M. M., 13 Oct 2017, In : Circulation. Cardiovascular genetics. 10, 5, p. e001778

    Research output: Contribution to journalArticle

  4. Epigenome-wide association study of leukocyte telomere length

    Lee, Y., Sun, D., Ori, A. P. S., Lu, A. T., Seeboth, A., Harris, S., Deary, I., Marioni, R., Soerensen, M., Mengel-From, J., Hjelmborg, J., Christensen, K., Wilson, J. G., Levy, D., Reiner, A. P., Chen, W., Li, S., Harris, J. R., Magnus, P., Aviv, A. & 2 others, Jugessur, A. & Horvath, S., 26 Aug 2019, In : Aging.

    Research output: Contribution to journalArticle

  5. Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

    Li, S., Lund, J. B., Christensen, K., Baumbach, J., Mengel-From, J., Kruse, T. A., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R., Deary, I. & Tan, Q., 28 Apr 2020, In : Genome Medicine. 12, 39.

    Research output: Contribution to journalArticle

  6. Identification, replication and characterization of epigenetic remodelling in the aging genome: A cross population analysis

    Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R., Deary, I. & Tan, Q., 15 Aug 2017, In : Scientific Reports. 7, p. 1-8 8183.

    Research output: Contribution to journalArticle

  7. Genome-wide association analyses of >200,000 individuals identify 58 genetic loci for chronic inflammation and highlights pathways that link inflammation and complex disorders

    Ligthart, S., Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Schraut, K. E., Joshi, P., Campbell, H., Wilson, J., Marioni, R. & Deary, I., 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706

    Research output: Contribution to journalArticle

  8. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

    Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M. M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., Joehanes, R., Guan, W., Brody, J. A., Elks, C., Marioni, R., Jhun, M. A., Agha, G., Bressler, J., Ward-Caviness, C. K., Chen, B. H., Huan, T., Bakulski, K. & 67 others, Salfati, E. L., Fiorito, G., Wahl, S., Schramm, K., Sha, J., Hernandez, D. G., Just, A. C., Smith, J. A., Sotoodehnia, N., Pilling, L. C., Pankow, J. S., Tsao, P. S., Liu, C., Zhao, W., Guarrera, S., Michopoulos, V. J., Smith, A. K., Peters, M. J., Melzer, D., Vokonas, P., Fornage, M., Prokisch, H., Bis, J. C., Chu, A. Y., Herder, C., Grallert, H., Yao, C., Shah, S., McRae, A. F., Lin, H., Horvath, S., Fallin, D., Hofman, A., Wareham, N. J., Wiggins, K. L., Feinberg, A. P., Starr, J. M., Visscher, P. M., Murabito, J. M., Kardia, S. L. R., Absher, D. M., Binder, E. B., Singleton, A. B., Bandinelli, S., Peters, A., Waldenberger, M., Matullo, G., Schwartz, J. D., Demerath, E. W., Uitterlinden, A. G., van Meurs, J. B. J., Franco, O. H., Chen, Y-D. I., Levy, D., Turner, S. T., Deary, I. J., Ressler, K. J., Dupuis, J., Ferrucci, L., Ong, K. K., Assimes, T. L., Boerwinkle, E., Koenig, W., Arnett, D. K., Baccarelli, A. A., Benjamin, E. J. & Dehghan, A., 12 Dec 2016, In : Genome Biology. 17, 255, 15 p.

    Research output: Contribution to journalArticle

  9. C-reactive protein, APOE genotype and longitudinal cognitive change in an older population

    Lima, T. A. S., Adler, A. L., Minett, T., Matthews, F. E., Brayne, C., Marioni, R. E. & on behalf of the Medical Research Council Cognitive Function and Ageing Study, Mar 2014, In : Age and Ageing. 43, 2

    Research output: Contribution to journalArticle

  10. DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy

    Lin, Q., Weidner, C. I., Costa, I. G., Marioni, R. E., Ferreira, M. R. P., Deary, I. J. & Wagner, W., 25 Feb 2016, In : Aging. 8, 2, p. 394-401 8 p.

    Research output: Contribution to journalArticle

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