Edinburgh Research Explorer

Riccardo Marioni

Senior Research Fellow

  1. 2020
  2. Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

    Zhang, Q., Sidorenko, J., Couvy-Duchesne, B., Marioni, R. E., Wright, M. J., Goate, A. M., Marcora, E., Huang, K., Porter, T., Laws, S., Sachdev, P. S., Mather, K. A., Armstrong, N. J., Thalamuthu, A., Brodaty, H., Yengo, L., Yang, J., Wray, N. R., Mcrae, A. F. & Visscher, P. M., 23 Sep 2020, In : Nature Communications. 4799 (2020).

    Research output: Contribution to journalArticle

  3. Birth weight associations with DNA methylation differences in an adult population

    Madden, R., McCartney, D. L., Walker, R., Hillary, R., Bermingham, M., Rawlick, K., Morris, S., Campbell, A., Porteous, D. J., Deary, I., Evans, K. L., Hafferty, J., McIntosh, A. & Marioni, R. E., 22 Sep 2020, (Accepted/In press) In : Epigenetics.

    Research output: Contribution to journalArticle

  4. Epigenome-wide analyses identify DNA methylation signatures of dementia risk

    Walker, R., Bermingham, M., Vaher, K., Morris, S., Clarke, T., Bretherick, A. D., Zeng, Y., Amador, C., Rawlik, K., Pandya, K., Hayward, C., Campbell, A., Porteous, D. J., McIntosh, A., Marioni, R. E. & Evans, K. L., 10 Aug 2020, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticle

  5. Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

    Stevenson, A., McCartney, D., Hillary, R., Campbell, A., Morris, S., Bermingham, M., Walker, R., Evans, K. L., Boutin, T., Hayward, C., Mcrae, A. F., McColl, B., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R. E., 27 Jul 2020, In : Clinical Epigenetics. 12, 113.

    Research output: Contribution to journalArticle

  6. Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults

    Hillary, R., Trejo-Banos, D., Kousathanas, A., McCartney, D. L., Harris, S., Stevenson, A., Patxot Beltran, M., Ojavee, S. E., Zhang, Q., Liewald, D., Ritchie, C., Evans, K. L., Tucker-Drob, E. M., Wray, N. R., Mcrae, A. F., Visscher, P. M., Deary, I., Robinson, M. R. & Marioni, R. E., 8 Jul 2020, In : Genome Medicine.

    Research output: Contribution to journalArticle

  7. Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

    Colicino, E., Marioni, R., Ward-Caviness, C., Gondalia, R., Guan, W., Chen, B. H., Tsai, P-C., Huan, T., Xu, G., Agha, G., Schwartz, J., Vokonas, P., Just, A. C., Starr, J., Mcrae, A. F., Wray, N., Visscher, P., Bressler, J., Zhang, W., Toshiko, T. & 29 others, Moore, A. Z., Pilling, L. C., Zhang, G., Stewart, J., Li, Y., Hou, L., Castillo-Fernandez, J., Spector, T. D., Kiel, D. P., Murabito, J. M., Liu, C., Mendelson, M., Assimes, T., Absher, D., Tsaho, P. S., Lu, A. T., Ferrucci, L., Wilson, R. P., Waldenberger, M., Prokisch, H., Bandinelli, S., Bell, J. T., Levy, D., Deary, I., Horvath, S., Pankow, J., Peters, A., Whitsel, E. A. & Baccarelli, A. A., Jul 2020, In : Aging. 12, 14, p. 14092—14124

    Research output: Contribution to journalArticle

  8. Epigenetic prediction of major depressive disorder

    Barbu, M., Shen, X., Walker, R., Howard, D. M., Evans, K., Whalley, H., Porteous, D., Morris, S., Deary, I., Zeng, Y., Marioni, R., Clarke, T. & McIntosh, A., 10 Jun 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  9. Bayesian reassessment of the epigenetic architecture of complex traits

    Trejo Baños, D., McCartney, D. L., Patxot Beltran, M., Anchieri, L., Battram, T., Christiansen, C., Costeira, R., Walker, R., Morris, S. W., Campbell, A., Zhang, Q., Porteous, D., Mcrae, A. F., Wray, N. R., Visscher, P. M., Haley, C., Evans, K., Deary, I., McIntosh, A., Hemani, G. & 3 others, Bell, J. T., Marioni, R. & Robinson, M. R., 8 Jun 2020, In : Nature Communications.

    Research output: Contribution to journalArticle

  10. Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection

    Messner, C. B., Demichev, V., Wendisch, D., Michalick, L., White, M., Freiwald, A., Textoris-taube, K., Vernardis, S. I., Egger, A., Kreidl, M., Ludwig, D., Kilian, C., Agostini, F., Zelezniak, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Von Kalle, C., Campbell, A. & 12 others, Hayward, C., Porteous, D. J., Marioni, R. E., Langenberg, C., Lilley, K. S., Kuebler, W. M., Mülleder, M., Drosten, C., Witzenrath, M., Kurth, F., Sander, L. E. & Ralser, M., 2 Jun 2020, In : Cell Systems.

    Research output: Contribution to journalArticle

  11. Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

    Li, S., Lund, J. B., Christensen, K., Baumbach, J., Mengel-From, J., Kruse, T. A., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R., Deary, I. & Tan, Q., 28 Apr 2020, In : Genome Medicine. 12, 39.

    Research output: Contribution to journalArticle

  12. DNA methylation in APOE: The relationship with Alzheimer’s and with cardiovascular health

    Mur, J., McCartney, D. L., Walker, R., Campbell, A., Bermingham, M., Morris, S., Porteous, D., McIntosh, A., Deary, I., Evans, K. & Marioni, R., 27 Apr 2020, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 6, 1

    Research output: Contribution to journalArticle

  13. DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

    Seeboth, A., McCartney, D. L., Wang, Y., Hillary, R., Stevenson, A., Walker, R., Campbell, A., Evans, K., McIntosh, A., Hägg, S., Deary, I. & Marioni, R., 26 Mar 2020, In : Clinical Epigenetics. 12, 49

    Research output: Contribution to journalArticle

  14. Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers

    Lund, J. B., Li, S., Baumbach, J., Christensen, K., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R. E., Deary, I. J. & Tan, Q., 10 Mar 2020, In : Journals of Gerontology, Series A.

    Research output: Contribution to journalArticle

  15. Epigenetic age acceleration and cognitive function in African-American adults in midlife: The Atherosclerosis Risk in Communities Study

    Bressler, J., Marioni, R. E., Walker, R. M., Xia, R., Gottesman, R. F., Windham, B. G., Grove, M. L., Guan, W., Pankow, J. S., Evans, K. L., Mcintosh, A. M., Deary, I. J., Mosley, T. H., Boerwinkle, E. & Fornage, M., Mar 2020, In : Journals of Gerontology, Series A. 75, 3, p. 473–480 glz245.

    Research output: Contribution to journalArticle

  16. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In : Nature Communications. 11, 800.

    Research output: Contribution to journalArticle

  17. Attitudes to ageing, biomarkers of ageing and mortality: The Lothian Birth Cohort 1936

    McLachlan, K., Cole, J., Harris, S., Marioni, R., Deary, I. & Gale, C., 28 Jan 2020, In : Journal of Epidemiology & Community Health.

    Research output: Contribution to journalArticle

  18. 2019
  19. An epigenome-wide association study of sex-specific chronological ageing

    Mccartney, D., Zhang, F., Hillary, R., Zhang, Q., Stevenson, A., Walker, R., Bermingham, M., Boutin, T., Morris, S., Campbell, A., Murray, A., Whalley, H., Porteous, D., Hayward, C., Evans, K., Chandra, T., Deary, I., McIntosh, A., Yang, J., Visscher, P. & 2 others, McRae, A. & Marioni, R., 31 Dec 2019, In : Genome Biology. 12, 1.

    Research output: Contribution to journalArticle

  20. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R., Stevenson, A., Cox, S., McCartney, D. L., Harris, S., Seeboth, A., Higham, J., Sproul, D., Taylor, A., Redmond, P., Corley, J., Pattie, A., Valdes Hernandez, M., Muñoz Maniega, S., Bastin, M., Wardlaw, J., Horvath, S., Ritchie, C., Spires-Jones, T., McIntosh, A. & 3 others, Evans, K. L., Deary, I. & Marioni, R. E., 3 Dec 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

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