Edinburgh Research Explorer

Riccardo Marioni

Senior Research Fellow

  1. 2021
  2. DNA methylation of blood cells is associated with prevalent type 2 diabetes in a meta-analysis of four European cohorts

    Juvinao-quintero, D. L., Marioni, R. E., Ochoa-rosales, C., Russ, T. C., Deary, I. J., Van Meurs, J. B. J., Voortman, T., Hivert, M., Sharp, G. C., Relton, C. L. & Elliott, H. R., 23 Feb 2021, In: Clinical Epigenetics. 13, 1

    Research output: Contribution to journalArticlepeer-review

  3. Creating and validating a DNA methylation-based proxy for interleukin-6

    Stevenson, A. J., Gadd, D. A., Hillary, R. F., Mccartney, D. L., Campbell, A., Walker, R. M., Evans, K. L., Harris, S. E., Spires-jones, T. L., Mcrae, A. F., Visscher, P. M., Mcintosh, A. M., Deary, I. J. & Marioni, R. E., 17 Feb 2021, In: Journal of Gerontology: Medical Sciences.

    Research output: Contribution to journalArticlepeer-review

  4. Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci

    Ahluwalia, T. S., Prins, B. P., Abdollahi, M., Armstrong, N. J., Aslibekyan, S., Bain, L., Jefferis, B., Baumert, J., Beekman, M., Ben-shlomo, Y., Bis, J. C., Mitchell, B. D., De Geus, E., Delgado, G. E., Marek, D., Eriksson, J., Kajantie, E., Kanoni, S., Kemp, J. P., Lu, C. & 106 others, Marioni, R. E., Mclachlan, S., Milaneschi, Y., Nolte, I. M., Petrelis, A. M., Porcu, E., Sabater-lleal, M., Naderi, E., Seppälä, I., Shah, T., Singhal, G., Standl, M., Teumer, A., Thalamuthu, A., Thiering, E., Trompet, S., Ballantyne, C. M., Benjamin, E. J., Casas, J. P., Toben, C., Dedoussis, G., Deelen, J., Durda, P., Engmann, J., Feitosa, M. F., Grallert, H., Hammarstedt, A., Harris, S. E., Homuth, G., Hottenga, J., Jalkanen, S., Jamshidi, Y., Jawahar, M. C., Jess, T., Kivimaki, M., Kleber, M. E., Lahti, J., Liu, Y., Marques-vidal, P., Mellström, D., Mooijaart, S. P., Müller-nurasyid, M., Penninx, B., Revez, J. A., Rossing, P., Räikkönen, K., Sattar, N., Scharnagl, H., Sennblad, B., Silveira, A., Pourcain, B. S., Timpson, N. J., Trollor, J., Van Dongen, J., Van Heemst, D., Visvikis-siest, S., Vollenweider, P., Völker, U., Waldenberger, M., Willemsen, G., Zabaneh, D., Morris, R. W., Arnett, D. K., Baune, B. T., Boomsma, D. I., Chang, Y. C., Deary, I. J., Deloukas, P., Eriksson, J. G., Evans, D. M., Ferreira, M. A., Gaunt, T., Gudnason, V., Hamsten, A., Heinrich, J., Hingorani, A., Humphries, S. E., Jukema, J. W., Koeing, W., Kumari, M., Kutalik, Z., Lawlor, D. A., Lehtimäki, T., März, W., Mather, K., Naitza, S., Nauck, M., Ohlsson, C., Price, J. F., Raitakari, O., Rice, K., Sachdev, P. S., Slagboom, E., Sørensen, T. I. A., Spector, T., Stacey, D., Stathopoulou, M. G., Tanaka, T., Wannamethee, S. G., Whincup, P., Rotter, J. I., Dehghan, A., Boerwinkle, E., Psaty, B. M., Snieder, H. & Alizadeh, B. Z., 30 Jan 2021, In: Human Molecular Genetics.

    Research output: Contribution to journalArticlepeer-review

  5. Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles

    Generation Scotland, 4 Jan 2021, In: Genome Medicine.

    Research output: Contribution to journalArticlepeer-review

  6. 2020
  7. Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

    Green, C., Shen, X., Stevenson, A. J., Conole, E. L. S., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., Lawrie, S. M., Evans, K. L., Walker, R. M., Morris, S. W., Porteous, D. J., Wardlaw, J. M., Douglas Steele, J., Waiter, G. D., Sandu, A., Campbell, A., Marioni, R. E. & 4 others, Cox, S. R., Cavanagh, J., Mcintosh, A. M. & Whalley, H. C., 19 Nov 2020, In: Brain, Behavior, and Immunity.

    Research output: Contribution to journalArticlepeer-review

  8. Birth weight associations with DNA methylation differences in an adult population

    Madden, R., McCartney, D. L., Walker, R., Hillary, R., Bermingham, M., Rawlick, K., Morris, S., Campbell, A., Porteous, D. J., Deary, I., Evans, K. L., Hafferty, J., McIntosh, A. & Marioni, R. E., 20 Oct 2020, In: Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  9. Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

    Zhang, Q., Sidorenko, J., Couvy-Duchesne, B., Marioni, R. E., Wright, M. J., Goate, A. M., Marcora, E., Huang, K., Porter, T., Laws, S., Sachdev, P. S., Mather, K. A., Armstrong, N. J., Thalamuthu, A., Brodaty, H., Yengo, L., Yang, J., Wray, N. R., Mcrae, A. F. & Visscher, P. M., 23 Sep 2020, In: Nature Communications. 4799 (2020).

    Research output: Contribution to journalArticlepeer-review

  10. Epigenome-wide analyses identify DNA methylation signatures of dementia risk

    Walker, R., Bermingham, M., Vaher, K., Morris, S., Clarke, T., Bretherick, A. D., Zeng, Y., Amador, C., Rawlik, K., Pandya, K., Hayward, C., Campbell, A., Porteous, D. J., McIntosh, A., Marioni, R. E. & Evans, K. L., 10 Aug 2020, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticlepeer-review

  11. Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

    Hillary, R. F., Stevenson, A. J., McCartney, D. L., Campbell, A., Walker, R. M., Howard, D. M., Ritchie, C. W., Horvath, S., Hayward, C., McIntosh, A. M., Porteous, D. J., Deary, I. J., Evans, K. L. & Marioni, R. E., 31 Jul 2020, In: Clinical Epigenetics. 12, 12 p., 115.

    Research output: Contribution to journalArticlepeer-review

  12. Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

    Stevenson, A., McCartney, D., Hillary, R., Campbell, A., Morris, S., Bermingham, M., Walker, R., Evans, K. L., Boutin, T., Hayward, C., Mcrae, A. F., McColl, B., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R. E., 27 Jul 2020, In: Clinical Epigenetics. 12, 113.

    Research output: Contribution to journalArticlepeer-review

  13. Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

    Hillary, R. F., Trejo-Banos, D., Kousathanas, A., McCartney, D. L., Harris, S. E., Stevenson, A. J., Patxot, M., Ojavee, S. E., Zhang, Q., Liewald, D. C., Ritchie, C. W., Evans, K. L., Tucker-Drob, E. M., Wray, N. R., McRae, A. F., Visscher, P. M., Deary, I. J., Robinson, M. R. & Marioni, R. E., 8 Jul 2020, In: Genome Medicine. 12, 60.

    Research output: Contribution to journalArticlepeer-review

  14. Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

    Colicino, E., Marioni, R., Ward-Caviness, C., Gondalia, R., Guan, W., Chen, B. H., Tsai, P-C., Huan, T., Xu, G., Agha, G., Schwartz, J., Vokonas, P., Just, A. C., Starr, J., Mcrae, A. F., Wray, N., Visscher, P., Bressler, J., Zhang, W., Toshiko, T. & 29 others, Moore, A. Z., Pilling, L. C., Zhang, G., Stewart, J., Li, Y., Hou, L., Castillo-Fernandez, J., Spector, T. D., Kiel, D. P., Murabito, J. M., Liu, C., Mendelson, M., Assimes, T., Absher, D., Tsaho, P. S., Lu, A. T., Ferrucci, L., Wilson, R. P., Waldenberger, M., Prokisch, H., Bandinelli, S., Bell, J. T., Levy, D., Deary, I., Horvath, S., Pankow, J., Peters, A., Whitsel, E. A. & Baccarelli, A. A., Jul 2020, In: Aging. 12, 14, p. 14092—14124

    Research output: Contribution to journalArticlepeer-review

  15. Epigenetic prediction of major depressive disorder

    Barbu, M. C., Shen, X., Walker, R. M., Howard, D. M., Evans, K. L., Whalley, H. C., Porteous, D. J., Morris, S. W., Deary, I. J., Zeng, Y., Marioni, R. E., Clarke, T-K. & McIntosh, A. M., 10 Jun 2020, In: Molecular Psychiatry. N/A, p. 1-12 13 p.

    Research output: Contribution to journalArticlepeer-review

  16. Bayesian reassessment of the epigenetic architecture of complex traits

    Trejo Baños, D., McCartney, D. L., Patxot, M., Anchieri, L., Battram, T., Christiansen, C., Costeira, R., Walker, R. M., Morris, S. W., Campbell, A., Zhang, Q., Porteous, D. J., McRae, A. F., Wray, N. R., Visscher, P. M., Haley, C. S., Evans, K. L., Deary, I. J., McIntosh, A. M., Hemani, G. & 3 others, Bell, J. T., Marioni, R. E. & Robinson, M. R., 8 Jun 2020, In: Nature Communications. 11, 2865.

    Research output: Contribution to journalArticlepeer-review

  17. Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection

    Messner, C. B., Demichev, V., Wendisch, D., Michalick, L., White, M., Freiwald, A., Textoris-taube, K., Vernardis, S. I., Egger, A., Kreidl, M., Ludwig, D., Kilian, C., Agostini, F., Zelezniak, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Von Kalle, C., Campbell, A. & 12 others, Hayward, C., Porteous, D. J., Marioni, R. E., Langenberg, C., Lilley, K. S., Kuebler, W. M., Mülleder, M., Drosten, C., Witzenrath, M., Kurth, F., Sander, L. E. & Ralser, M., 2 Jun 2020, In: Cell Systems.

    Research output: Contribution to journalArticlepeer-review

  18. Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

    Li, S., Lund, J. B., Christensen, K., Baumbach, J., Mengel-From, J., Kruse, T. A., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R., Deary, I. & Tan, Q., 28 Apr 2020, In: Genome Medicine. 12, 39.

    Research output: Contribution to journalArticlepeer-review

  19. DNA methylation in APOE: The relationship with Alzheimer’s and with cardiovascular health

    Mur, J., McCartney, D. L., Walker, R., Campbell, A., Bermingham, M., Morris, S., Porteous, D., McIntosh, A., Deary, I., Evans, K. & Marioni, R., 27 Apr 2020, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 6, 1

    Research output: Contribution to journalArticlepeer-review

  20. DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

    Seeboth, A., McCartney, D. L., Wang, Y., Hillary, R., Stevenson, A., Walker, R., Campbell, A., Evans, K., McIntosh, A., Hägg, S., Deary, I. & Marioni, R., 26 Mar 2020, In: Clinical Epigenetics. 12, 49

    Research output: Contribution to journalArticlepeer-review

  21. Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers

    Lund, J. B., Li, S., Baumbach, J., Christensen, K., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R. E., Deary, I. J. & Tan, Q., 10 Mar 2020, In: Journal of Gerontology: Medical Sciences.

    Research output: Contribution to journalArticlepeer-review

  22. Epigenetic age acceleration and cognitive function in African-American adults in midlife: The Atherosclerosis Risk in Communities Study

    Bressler, J., Marioni, R. E., Walker, R. M., Xia, R., Gottesman, R. F., Windham, B. G., Grove, M. L., Guan, W., Pankow, J. S., Evans, K. L., Mcintosh, A. M., Deary, I. J., Mosley, T. H., Boerwinkle, E. & Fornage, M., Mar 2020, In: Journal of Gerontology: Medical Sciences. 75, 3, p. 473–480 glz245.

    Research output: Contribution to journalArticlepeer-review

  23. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In: Nature Communications. 11, 800.

    Research output: Contribution to journalArticlepeer-review

  24. Attitudes to ageing, biomarkers of ageing and mortality: The Lothian Birth Cohort 1936

    McLachlan, K., Cole, J., Harris, S., Marioni, R., Deary, I. & Gale, C., 28 Jan 2020, In: Journal of Epidemiology & Community Health.

    Research output: Contribution to journalArticlepeer-review

  25. 2019
  26. An epigenome-wide association study of sex-specific chronological ageing

    McCartney, D. L., Zhang, F., Hillary, R. F., Zhang, Q., Stevenson, A. J., Walker, R. M., Bermingham, M. L., Boutin, T., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., Hayward, C., Evans, K. L., Chandra, T., Deary, I. J., McIntosh, A. M., Yang, J., Visscher, P. M. & 2 others, McRae, A. F. & Marioni, R. E., 31 Dec 2019, In: Genome Biology. 12, 1.

    Research output: Contribution to journalArticlepeer-review

  27. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., Corley, J., Pattie, A., del C. Valdés Hernández, M., Muñoz-Maniega, S., Bastin, M. E., Wardlaw, J. M., Horvath, S., Ritchie, C. W., Spires-Jones, T. L., McIntosh, A. M. & 3 others, Evans, K. L., Deary, I. J. & Marioni, R. E., 3 Dec 2019, In: Molecular Psychiatry. N/A, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  28. Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

    Hillary, R., McCartney, D. L., Harris, S., Stevenson, A., Seeboth, A., Zhang, Q., Liewald, D., Evans, K. L., Ritchie, C., Tucker-Drob, E. M., Wray, N. R., Mcrae, A. F., Visscher, P. M., Deary, I. & Marioni, R. E., Dec 2019, In: Nature Communications. 10, 3160.

    Research output: Contribution to journalArticlepeer-review

  29. Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

    Stevenson, A., McCartney, D. L., Hillary, R., Redmond, P., Taylor, A., Zhang, Q., McRae, A., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R., 28 Nov 2019, In: Translational Psychiatry. 9, 323.

    Research output: Contribution to journalArticlepeer-review

  30. DNA methylation Aging Clocks: Challenges & Recommendations

    Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., Ideker, T., Issa, J-P. J., Kelsey, K. T., Marioni, R., Reik, W., Relton, C. L., Schalkwyk, L. C., Teschendorff, A. E., Wagner, W., Zhang, K. & 1 others, Rakyan, V. K., 25 Nov 2019, In: Genome Biology.

    Research output: Contribution to journalArticlepeer-review

  31. A meta-analysis of genome-wide association studies of epigenetic age acceleration

    Gibson, J., Russ, T. C., Clarke, T-K., Howard, D. M., Hillary, R. F., Evans, K. L., Walker, R. M., Bermingham, M. L., Morris, S. W., Campbell, A., Hayward, C., Murray, A. D., Porteous, D. J., Horvath, S., Lu, A. T., McIntosh, A. M., Whalley, H. C. & Marioni, R. E., 18 Nov 2019, In: PLoS Genetics. 15, 11, e1008104.

    Research output: Contribution to journalArticlepeer-review

  32. Epigenome-wide association study of leukocyte telomere length

    Lee, Y., Sun, D., Ori, A. P. S., Lu, A. T., Seeboth, A., Harris, S., Deary, I., Marioni, R., Soerensen, M., Mengel-From, J., Hjelmborg, J., Christensen, K., Wilson, J. G., Levy, D., Reiner, A. P., Chen, W., Li, S., Harris, J. R., Magnus, P., Aviv, A. & 2 others, Jugessur, A. & Horvath, S., 26 Aug 2019, In: Aging.

    Research output: Contribution to journalArticlepeer-review

  33. Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

    Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., He, J., Fan, D., Fowdar, J., Kennedy, M., Pitcher, T., Pearson, J., Halliday, G., Kwok, J. B., Hickie, I., Lewis, S., Anderson, T., Silburn, P. A., Mellick, G. D., Harris, S. E. & 13 others, Redmond, P., Murray, A. D., Porteous, D. J., Haley, C. S., Evans, K. L., Mcintosh, A. M., Yang, J., Gratten, J., Marioni, R. E., Wray, N. R., Deary, I. J., Mcrae, A. F. & Visscher, P. M., 23 Aug 2019, In: Genome Medicine. 11, 1, 54.

    Research output: Contribution to journalArticlepeer-review

  34. Age-related clonal haematopoiesis is associated with increased epigenetic age

    Robertson, N. A., Hillary, R. F., McCartney, D. L., Terradas-Terradas, M., Higham, J., Sproul, D., Deary, I. J., Kirschner, K., Marioni, R. E. & Chandra, T., 19 Aug 2019, In: Current Biology. 29, 16, p. R786-R787

    Research output: Contribution to journalArticlepeer-review

  35. DNA methylation-based estimator of telomere length

    Lu, A. T., Seeboth, A., Tsai, P-C., Sun, D., Quach, A., Reiner, A. P., Kooperberg, C., Ferrucci, L., Hou, L., Baccarelli, A. A., Li, Y., Harris, S. E., Corley, J., Taylor, A., Deary, I. J., Stewart, J. D., Whitsel, E. A., Assimes, T. L., Chen, W., Li, S. & 7 others, Mangino, M., Bell, J. T., Wilson, J., Aviv, A., Marioni, R. E., Raj, K. & Horvath, S., 18 Aug 2019, In: Aging. 11

    Research output: Contribution to journalArticlepeer-review

  36. Correction: GWAS on family history of Alzheimer’s disease

    Marioni, R. E., Harris, S. E., Zhang, Q., Mcrae, A. F., Hagenaars, S. P., Hill, W. D., Davies, G., Ritchie, C. W., Gale, C. R., Starr, J. M., Goate, A. M., Porteous, D. J., Yang, J., Evans, K. L., Deary, I. J., Wray, N. R. & Visscher, P. M., 6 Jun 2019, In: Translational Psychiatry. 9, 1

    Research output: Contribution to journalComment/debate

  37. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S-C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L-P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 May 2019, In: Nature Communications. 10, 1, p. 2068

    Research output: Contribution to journalArticle

  38. Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

    Grotzinger, A., Rhemtulla, M., Vlaming, R. D., Ritchie, S. J., Mallard, T. T., Hill, W. D., Hill, F., Marioni, R., McIntosh, A., Deary, I., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., May 2019, In: Nature Human Behaviour. 3, 5, p. 513-525

    Research output: Contribution to journalArticlepeer-review

  39. Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait

    Chundru, V. K., Marioni, R. E., Prendergast, J. G. D., Vallerga, C. L., Lin, T., Berveridge, A. J., Consortium, S., Gratten, J., Hume, D. A., Deary, I. J., Wray, N. R., Visscher, P. M. & McRae, A. F., 30 Apr 2019, In: Genetics.

    Research output: Contribution to journalArticlepeer-review

  40. Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

    Howard, D. M., Adams, M. J., Clarke, T-K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 20 others, Berger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & McIntosh, A. M., 31 Mar 2019, In: Nature Neuroscience. 22, 3, p. 343–352 10 p.

    Research output: Contribution to journalArticlepeer-review

  41. An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

    Hamilton, O., Zhang, Q., Mcrae, A. F., Walker, R., Morris, S., Redmond, P., Campbell, A., Murray, A., Porteous, D., Evans, K., McIntosh, A., Deary, I. & Marioni, R., 6 Mar 2019, In: International Journal of Obesity.

    Research output: Contribution to journalArticlepeer-review

  42. A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

    Hill, W. D., Marioni, R. E., Maghzian, O., Ritchie, S. J., Hagenaars, S. P., McIntosh, A. M., Gale, C. R., Davies, G. & Deary, I. J., 28 Feb 2019, In: Molecular Psychiatry. 24, 2, p. 169-181 13 p.

    Research output: Contribution to journalArticlepeer-review

  43. Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

    Lund, J., Li, S., Christensen, K., Mengel-From, J., Soerensen, M., Marioni, R., Starr, J., Pattie, A., Deary, I., Baumbach, J. & Tan, Q., 21 Feb 2019, In: Aging Cell.

    Research output: Contribution to journalArticlepeer-review

  44. Polygenic predictors of age-related decline in cognitive ability

    Ritchie, S. J., Hill, W. D., Marioni, R., Davies, G., Hagenaars, S., Harris, S., Cox, S., Taylor, A., Corley, J., Pattie, A., Redmond, P., Starr, J. & Deary, I., 13 Feb 2019, In: Molecular Psychiatry. p. 1-15

    Research output: Contribution to journalArticlepeer-review

  45. Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

    Olova, N., Simpson, D. J., Marioni, R. E. & Chandra, T., 1 Feb 2019, In: Aging Cell. 18, 1, e12877.

    Research output: Contribution to journalArticlepeer-review

  46. DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

    Lund, J., Li, S., Baumbach, J., Svane, A. M., Hjelmborg, J., Christiansen, L., Christensen, K., Redmond, P., Marioni, R., Deary, I. & Tan, Q., Feb 2019, In: Clinical Epigenetics. 11, 23, p. 1-8

    Research output: Contribution to journalArticlepeer-review

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