Edinburgh Research Explorer

Riccardo Marioni

Senior Research Fellow

  1. 2020
  2. Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

    Zhang, Q., Sidorenko, J., Couvy-Duchesne, B., Marioni, R. E., Wright, M. J., Goate, A. M., Marcora, E., Huang, K., Porter, T., Laws, S., Sachdev, P. S., Mather, K. A., Armstrong, N. J., Thalamuthu, A., Brodaty, H., Yengo, L., Yang, J., Wray, N. R., Mcrae, A. F. & Visscher, P. M., 23 Sep 2020, In : Nature Communications. 4799 (2020).

    Research output: Contribution to journalArticle

  3. Birth weight associations with DNA methylation differences in an adult population

    Madden, R., McCartney, D. L., Walker, R., Hillary, R., Bermingham, M., Rawlick, K., Morris, S., Campbell, A., Porteous, D. J., Deary, I., Evans, K. L., Hafferty, J., McIntosh, A. & Marioni, R. E., 22 Sep 2020, (Accepted/In press) In : Epigenetics.

    Research output: Contribution to journalArticle

  4. Epigenome-wide analyses identify DNA methylation signatures of dementia risk

    Walker, R., Bermingham, M., Vaher, K., Morris, S., Clarke, T., Bretherick, A. D., Zeng, Y., Amador, C., Rawlik, K., Pandya, K., Hayward, C., Campbell, A., Porteous, D. J., McIntosh, A., Marioni, R. E. & Evans, K. L., 10 Aug 2020, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticle

  5. Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

    Stevenson, A., McCartney, D., Hillary, R., Campbell, A., Morris, S., Bermingham, M., Walker, R., Evans, K. L., Boutin, T., Hayward, C., Mcrae, A. F., McColl, B., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R. E., 27 Jul 2020, In : Clinical Epigenetics. 12, 113.

    Research output: Contribution to journalArticle

  6. Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults

    Hillary, R., Trejo-Banos, D., Kousathanas, A., McCartney, D. L., Harris, S., Stevenson, A., Patxot Beltran, M., Ojavee, S. E., Zhang, Q., Liewald, D., Ritchie, C., Evans, K. L., Tucker-Drob, E. M., Wray, N. R., Mcrae, A. F., Visscher, P. M., Deary, I., Robinson, M. R. & Marioni, R. E., 8 Jul 2020, In : Genome Medicine.

    Research output: Contribution to journalArticle

  7. Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

    Colicino, E., Marioni, R., Ward-Caviness, C., Gondalia, R., Guan, W., Chen, B. H., Tsai, P-C., Huan, T., Xu, G., Agha, G., Schwartz, J., Vokonas, P., Just, A. C., Starr, J., Mcrae, A. F., Wray, N., Visscher, P., Bressler, J., Zhang, W., Toshiko, T. & 29 others, Moore, A. Z., Pilling, L. C., Zhang, G., Stewart, J., Li, Y., Hou, L., Castillo-Fernandez, J., Spector, T. D., Kiel, D. P., Murabito, J. M., Liu, C., Mendelson, M., Assimes, T., Absher, D., Tsaho, P. S., Lu, A. T., Ferrucci, L., Wilson, R. P., Waldenberger, M., Prokisch, H., Bandinelli, S., Bell, J. T., Levy, D., Deary, I., Horvath, S., Pankow, J., Peters, A., Whitsel, E. A. & Baccarelli, A. A., Jul 2020, In : Aging. 12, 14, p. 14092—14124

    Research output: Contribution to journalArticle

  8. Epigenetic prediction of major depressive disorder

    Barbu, M., Shen, X., Walker, R., Howard, D. M., Evans, K., Whalley, H., Porteous, D., Morris, S., Deary, I., Zeng, Y., Marioni, R., Clarke, T. & McIntosh, A., 10 Jun 2020, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  9. Bayesian reassessment of the epigenetic architecture of complex traits

    Trejo Baños, D., McCartney, D. L., Patxot Beltran, M., Anchieri, L., Battram, T., Christiansen, C., Costeira, R., Walker, R., Morris, S. W., Campbell, A., Zhang, Q., Porteous, D., Mcrae, A. F., Wray, N. R., Visscher, P. M., Haley, C., Evans, K., Deary, I., McIntosh, A., Hemani, G. & 3 others, Bell, J. T., Marioni, R. & Robinson, M. R., 8 Jun 2020, In : Nature Communications.

    Research output: Contribution to journalArticle

  10. Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection

    Messner, C. B., Demichev, V., Wendisch, D., Michalick, L., White, M., Freiwald, A., Textoris-taube, K., Vernardis, S. I., Egger, A., Kreidl, M., Ludwig, D., Kilian, C., Agostini, F., Zelezniak, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Von Kalle, C., Campbell, A. & 12 others, Hayward, C., Porteous, D. J., Marioni, R. E., Langenberg, C., Lilley, K. S., Kuebler, W. M., Mülleder, M., Drosten, C., Witzenrath, M., Kurth, F., Sander, L. E. & Ralser, M., 2 Jun 2020, In : Cell Systems.

    Research output: Contribution to journalArticle

  11. Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

    Li, S., Lund, J. B., Christensen, K., Baumbach, J., Mengel-From, J., Kruse, T. A., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R., Deary, I. & Tan, Q., 28 Apr 2020, In : Genome Medicine. 12, 39.

    Research output: Contribution to journalArticle

  12. DNA methylation in APOE: The relationship with Alzheimer’s and with cardiovascular health

    Mur, J., McCartney, D. L., Walker, R., Campbell, A., Bermingham, M., Morris, S., Porteous, D., McIntosh, A., Deary, I., Evans, K. & Marioni, R., 27 Apr 2020, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 6, 1

    Research output: Contribution to journalArticle

  13. DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

    Seeboth, A., McCartney, D. L., Wang, Y., Hillary, R., Stevenson, A., Walker, R., Campbell, A., Evans, K., McIntosh, A., Hägg, S., Deary, I. & Marioni, R., 26 Mar 2020, In : Clinical Epigenetics. 12, 49

    Research output: Contribution to journalArticle

  14. Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers

    Lund, J. B., Li, S., Baumbach, J., Christensen, K., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R. E., Deary, I. J. & Tan, Q., 10 Mar 2020, In : Journals of Gerontology, Series A.

    Research output: Contribution to journalArticle

  15. Epigenetic age acceleration and cognitive function in African-American adults in midlife: The Atherosclerosis Risk in Communities Study

    Bressler, J., Marioni, R. E., Walker, R. M., Xia, R., Gottesman, R. F., Windham, B. G., Grove, M. L., Guan, W., Pankow, J. S., Evans, K. L., Mcintosh, A. M., Deary, I. J., Mosley, T. H., Boerwinkle, E. & Fornage, M., Mar 2020, In : Journals of Gerontology, Series A. 75, 3, p. 473–480 glz245.

    Research output: Contribution to journalArticle

  16. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In : Nature Communications. 11, 800.

    Research output: Contribution to journalArticle

  17. Attitudes to ageing, biomarkers of ageing and mortality: The Lothian Birth Cohort 1936

    McLachlan, K., Cole, J., Harris, S., Marioni, R., Deary, I. & Gale, C., 28 Jan 2020, In : Journal of Epidemiology & Community Health.

    Research output: Contribution to journalArticle

  18. 2019
  19. An epigenome-wide association study of sex-specific chronological ageing

    Mccartney, D., Zhang, F., Hillary, R., Zhang, Q., Stevenson, A., Walker, R., Bermingham, M., Boutin, T., Morris, S., Campbell, A., Murray, A., Whalley, H., Porteous, D., Hayward, C., Evans, K., Chandra, T., Deary, I., McIntosh, A., Yang, J., Visscher, P. & 2 others, McRae, A. & Marioni, R., 31 Dec 2019, In : Genome Biology. 12, 1.

    Research output: Contribution to journalArticle

  20. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R., Stevenson, A., Cox, S., McCartney, D. L., Harris, S., Seeboth, A., Higham, J., Sproul, D., Taylor, A., Redmond, P., Corley, J., Pattie, A., Valdes Hernandez, M., Muñoz Maniega, S., Bastin, M., Wardlaw, J., Horvath, S., Ritchie, C., Spires-Jones, T., McIntosh, A. & 3 others, Evans, K. L., Deary, I. & Marioni, R. E., 3 Dec 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  21. Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

    Hillary, R., McCartney, D. L., Harris, S., Stevenson, A., Seeboth, A., Zhang, Q., Liewald, D., Evans, K. L., Ritchie, C., Tucker-Drob, E. M., Wray, N. R., Mcrae, A. F., Visscher, P. M., Deary, I. & Marioni, R. E., Dec 2019, In : Nature Communications. 10, 3160.

    Research output: Contribution to journalArticle

  22. Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

    Stevenson, A., McCartney, D. L., Hillary, R., Redmond, P., Taylor, A., Zhang, Q., McRae, A., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R., 28 Nov 2019, In : Translational Psychiatry. 9, 323.

    Research output: Contribution to journalArticle

  23. DNA methylation Aging Clocks: Challenges & Recommendations

    Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., Ideker, T., Issa, J-P. J., Kelsey, K. T., Marioni, R., Reik, W., Relton, C. L., Schalkwyk, L. C., Teschendorff, A. E., Wagner, W., Zhang, K. & 1 others, Rakyan, V. K., 25 Nov 2019, In : Genome Biology.

    Research output: Contribution to journalArticle

  24. A meta-analysis of genome-wide association studies of epigenetic age acceleration

    Gibson, J., Russ, T., Clarke, T-K., Howard, D., Hillary, R., Evans, K. L., Walker, R., Bermingham, M., Morris, S., Campbell, A., Hayward, C., Murray, A., Porteous, D. J., Horvath, S., Lu, A. T., McIntosh, A., Whalley, H. & Marioni, R. E., 18 Nov 2019, In : PLoS Genetics. 15, 11, 53 p., e1008104.

    Research output: Contribution to journalArticle

  25. Epigenome-wide association study of leukocyte telomere length

    Lee, Y., Sun, D., Ori, A. P. S., Lu, A. T., Seeboth, A., Harris, S., Deary, I., Marioni, R., Soerensen, M., Mengel-From, J., Hjelmborg, J., Christensen, K., Wilson, J. G., Levy, D., Reiner, A. P., Chen, W., Li, S., Harris, J. R., Magnus, P., Aviv, A. & 2 others, Jugessur, A. & Horvath, S., 26 Aug 2019, In : Aging.

    Research output: Contribution to journalArticle

  26. Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

    Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., He, J., Fan, D., Fowdar, J., Kennedy, M., Pitcher, T., Pearson, J., Halliday, G., Kwok, J. B., Hickie, I., Lewis, S., Anderson, T., Silburn, P. A., Mellick, G. D., Harris, S. E. & 13 others, Redmond, P., Murray, A. D., Porteous, D. J., Haley, C. S., Evans, K. L., Mcintosh, A. M., Yang, J., Gratten, J., Marioni, R. E., Wray, N. R., Deary, I. J., Mcrae, A. F. & Visscher, P. M., 23 Aug 2019, In : Genome Medicine. 11, 1, 54.

    Research output: Contribution to journalArticle

  27. Age-related clonal haematopoiesis is associated with increased epigenetic age

    Robertson, N., Hillary, R., McCartney, D. L., Terradas Terradas, M., Higham, J., Sproul, D., Deary, I., Kirschner, K., Marioni, R. & Chandra, T., 19 Aug 2019, In : Current Biology. 29, 16, p. R786-R787

    Research output: Contribution to journalArticle

  28. DNA methylation-based estimator of telomere length

    Lu, A. T., Seeboth, A., Tsai, P-C., Sun, D., Quach, A., Reiner, A. P., Kooperberg, C., Ferrucci, L., Hou, L., Baccarelli, A. A., Li, Y., Harris, S. E., Corley, J., Taylor, A., Deary, I. J., Stewart, J. D., Whitsel, E. A., Assimes, T. L., Chen, W., Li, S. & 7 others, Mangino, M., Bell, J. T., Wilson, J., Aviv, A., Marioni, R. E., Raj, K. & Horvath, S., 18 Aug 2019, In : Aging. 11

    Research output: Contribution to journalArticle

  29. Correction: GWAS on family history of Alzheimer’s disease

    Marioni, R. E., Harris, S. E., Zhang, Q., Mcrae, A. F., Hagenaars, S. P., Hill, W. D., Davies, G., Ritchie, C. W., Gale, C. R., Starr, J. M., Goate, A. M., Porteous, D. J., Yang, J., Evans, K. L., Deary, I. J., Wray, N. R. & Visscher, P. M., 6 Jun 2019, In : Translational Psychiatry. 9, 1

    Research output: Contribution to journalComment/debate

  30. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S-C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L-P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 May 2019, In : Nature Communications. 10, 1, p. 2068

    Research output: Contribution to journalArticle

  31. Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

    Grotzinger, A., Rhemtulla, M., Vlaming, R. D., Ritchie, S. J., Mallard, T. T., Hill, W. D., Hill, F., Marioni, R., McIntosh, A., Deary, I., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., May 2019, In : Nature Human Behaviour. 3, 5, p. 513-525

    Research output: Contribution to journalArticle

  32. Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait

    Chundru, V. K., Marioni, R. E., Prendergast, J. G. D., Vallerga, C. L., Lin, T., Berveridge, A. J., Consortium, S., Gratten, J., Hume, D. A., Deary, I. J., Wray, N. R., Visscher, P. M. & McRae, A. F., 30 Apr 2019, In : Genetics.

    Research output: Contribution to journalArticle

  33. An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

    Hamilton, O., Zhang, Q., Mcrae, A. F., Walker, R., Morris, S., Redmond, P., Campbell, A., Murray, A., Porteous, D., Evans, K., McIntosh, A., Deary, I. & Marioni, R., 6 Mar 2019, In : International Journal of Obesity.

    Research output: Contribution to journalArticle

  34. Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

    Lund, J., Li, S., Christensen, K., Mengel-From, J., Soerensen, M., Marioni, R., Starr, J., Pattie, A., Deary, I., Baumbach, J. & Tan, Q., 21 Feb 2019, In : Aging Cell.

    Research output: Contribution to journalArticle

  35. Polygenic predictors of age-related decline in cognitive ability

    Ritchie, S. J., Hill, W. D., Marioni, R., Davies, G., Hagenaars, S., Harris, S., Cox, S., Taylor, A., Corley, J., Pattie, A., Redmond, P., Starr, J. & Deary, I., 13 Feb 2019, In : Molecular Psychiatry. p. 1-15

    Research output: Contribution to journalArticle

  36. Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

    Howard, D. M., Adams, M. J., Clarke, T., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 18 others, Berger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & Mcintosh, A. M., 4 Feb 2019, In : Nature Neuroscience. 22, 3, p. 343–352 10 p.

    Research output: Contribution to journalArticle

  37. Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

    Olova, N., Simpson, D. J., Marioni, R. E. & Chandra, T., 1 Feb 2019, In : Aging Cell. 18, 1, e12877.

    Research output: Contribution to journalArticle

  38. A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

    Hill, W. D., Marioni, R., Maghzian, O., Ritchie, S. J., Hagenaars, S. P., McIntosh, A., Gale, C., Davies, G. & Deary, I., Feb 2019, In : Molecular Psychiatry. 24, 2, p. 169-181

    Research output: Contribution to journalArticle

  39. DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

    Lund, J., Li, S., Baumbach, J., Svane, A. M., Hjelmborg, J., Christiansen, L., Christensen, K., Redmond, P., Marioni, R., Deary, I. & Tan, Q., Feb 2019, In : Clinical Epigenetics. 11, 23, p. 1-8

    Research output: Contribution to journalArticle

  40. Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

    Erzurumluoglu, A. M., Liu, M., Jackson, V. E., Barnes, D. R., Datta, G., Melbourne, C. A., Young, R. D., Batini, C., Surendran, P., Jiang, T., Adnan, S. D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A. C., Asselbergs, F. W., Baumbach, C., Bierut, L., Bertelsen, S., Boehnke, M. & 156 others, Bots, M. L., Brazel, D. M., Chambers, J. C., Chang-claude, J., Chen, C., Corley, J., Chou, Y., David, S. P., De Boer, R. A., De Leeuw, C. A., Dennis, J. G., Dominiczak, A. F., Dunning, A. M., Easton, D. F., Eaton, C., Elliott, P., Evangelou, E., Faul, J. D., Foroud, T., Goate, A., Gong, J., Grabe, H. J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A. R., Harris, S. E., Hattersley, A., Heath, A., Hsu, C., Iacono, W. G., Kanoni, S., Kapoor, M., Kaprio, J., Kardia, S. L., Karpe, F., Kontto, J., Kooner, J. S., Kooperberg, C., Kuulasmaa, K., Laakso, M., Lai, D., Langenberg, C., Le, N., Lettre, G., Loukola, A., Luan, J., Madden, P. A. F., Mangino, M., Marioni, R. E., Marouli, E., Marten, J., Martin, N. G., Mcgue, M., Michailidou, K., Mihailov, E., Moayyeri, A., Moitry, M., Müller-nurasyid, M., Naheed, A., Nauck, M., Neville, M. J., Nielsen, S. F., North, K., Perola, M., Pharoah, P. D. P., Pistis, G., Polderman, T. J., Posthuma, D., Poulter, N., Qaiser, B., Rasheed, A., Reiner, A., Renström, F., Rice, J., Rohde, R., Rolandsson, O., Samani, N. J., Samuel, M., Schlessinger, D., Scholte, S. H., Scott, R. A., Sever, P., Shao, Y., Shrine, N., Smith, J. A., Starr, J. M., Stirrups, K., Stram, D., Stringham, H. M., Tachmazidou, I., Tardif, J., Thompson, D. J., Tindle, H. A., Tragante, V., Trompet, S., Turcot, V., Tyrrell, J., Vaartjes, I., Van Der Leij, A. R., Van Der Meer, P., Varga, T. V., Verweij, N., Völzke, H., Wareham, N. J., Warren, H. R., Weir, D. R., Weiss, S., Wetherill, L., Yaghootkar, H., Yavas, E., Jiang, Y., Chen, F., Zhan, X., Zhang, W., Zhao, W., Zhao, W., Zhou, K., Amouyel, P., Blankenberg, S., Caulfield, M. J., Chowdhury, R., Cucca, F., Deary, I. J., Deloukas, P., Di Angelantonio, E., Ferrario, M., Ferrières, J., Franks, P. W., Frayling, T. M., Frossard, P., Hall, I. P., Hayward, C., Jansson, J., Jukema, J. W., Kee, F., Männistö, S., Metspalu, A., Munroe, P. B., Nordestgaard, B. G., Palmer, C. N. A., Salomaa, V., Sattar, N., Spector, T., Strachan, D. P., Van Der Harst, P., Zeggini, E., Saleheen, D., Butterworth, A. S., Wain, L. V., Abecasis, G. R., Danesh, J., Tobin, M. D., Vrieze, S., Liu, D. J. & Howson, J. M. M., 7 Jan 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  41. Tracking the epigenetic clock across the human life course: A meta-analysis of longitudinal cohort data

    Marioni, R., Suderman, M. J., Chen, B. H., Horvath, S., Bandinelli, S., Morris, T. J., Becker, S., Ferrucci, L., Pedersen, N. L., Relton, C. L., Deary, I. & Hägg, S., Jan 2019, In : Journals of Gerontology, Series A. 74, 1, p. 1-5 gly060.

    Research output: Contribution to journalArticle

  42. 2018
  43. Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

    Stevenson, A., McCartney, D. L., Harris, S., Taylor, A., Redmond, P., Starr, J., Zhang, Q., McRae, A. F., Wray, N. R., Spires-Jones, T., McColl, B., McIntosh, A., Deary, I. & Marioni, R., 20 Dec 2018, In : Clinical Epigenetics.

    Research output: Contribution to journalArticle

  44. Identification of 55,000 Replicated DNA Methylation QTL

    McRae, A. F., Marioni, R. E., Shah, S., Yang, J., Powell, J. E., Harris, S. E., Gibson, J., Henders, A. K., Bowdler, L., Painter, J. N., Murphy, L., Martin, N. G., Starr, J. M., Wray, N. R., Deary, I. J., Visscher, P. M. & Montgomery, G. W., 4 Dec 2018, In : Scientific Reports. 8, 1, p. 1-9 17605.

    Research output: Contribution to journalArticle

  45. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    Franceschini, N., Giambartolomei, C., De Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., Lovering, R. C., Tajuddin, S. M., Winkler, T. W., Graff, M., Kavousi, M., Dale, C., Smith, A. V., Hofer, E., Van Leeuwen, E. M., Nolte, I. M., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N. & 137 others, Franzén, O., Joshi, P. K., Noordam, R., Marioni, R. E., Hwang, S., Musani, S. K., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, A. B., Hofman, A., Teumer, A., Cox, A. J., Uitterlinden, A. G., Wong, A., Smit, A. J., Newman, A. B., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, B. W., Langefeld, C. D., Wassel, C. L., Tzourio, C., Fava, C., Baldassarre, D., O’leary, D. H., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, E. E., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, H. S., Deary, I. J., Jukema, J. W., De Graaf, J., Price, J., Pott, J., Hopewell, J. C., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, K. D., Dhana, K., Kiemeney, L. A. L. M., Lind, L., Raffield, L. M., Launer, L. J., Holdt, L. M., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, M. A., Melander, O., Raitakari, O., Franco, O. H., Rueda-ochoa, O. L., Roussos, P., Whincup, P. H., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., De Mutsert, R., Morris, R. W., Strawbridge, R. J., Wannamethee, S. G., Hägg, S., Shah, S., Mclachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, S. R., Ring, S., Harris, T. B., Lehtimäki, T., Galesloot, T. E., Shah, T., De Faire, U., Plagnol, V., Rosamond, W. D., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., Dehghan, A., Seldenrijk, A., Morrison, A. C., Hamsten, A., Psaty, B. M., Van Duijn, C. M., Lawlor, D. A., Mook-kanamori, D. O., Bowden, D. W., Schmidt, H., Wilson, J. G., Rotter, J. I., Wardlaw, J. M., Deanfield, J., Halcox, J., Lyytikäinen, L., Loeffler, M., Evans, M. K., Debette, S., Humphries, S. E., Völker, U., Gudnason, V., Hingorani, A. D., Björkegren, J. L. M., Casas, J. P. & O’donnell, C. J., 3 Dec 2018, In : Nature Communications. 9, 1, 5141.

    Research output: Contribution to journalArticle

  46. Association of facial ageing with DNA methylation and epigenetic age predictions

    Marioni, R. E., Belsky, D. W., Deary, I. J. & Wagner, W., 8 Nov 2018, In : Clinical Epigenetics. 10, 140, p. 1-3

    Research output: Contribution to journalShort survey

  47. Genome-wide association analyses of >200,000 individuals identify 58 genetic loci for chronic inflammation and highlights pathways that link inflammation and complex disorders

    Ligthart, S., Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Schraut, K. E., Joshi, P., Campbell, H., Wilson, J., Marioni, R. & Deary, I., 1 Nov 2018, In : American Journal of Human Genetics. 103, 5, p. 691-706

    Research output: Contribution to journalArticle

  48. Epigenetic signatures of starting and stopping smoking

    McCartney, D. L., Stevenson, A. J., Hillary, R. F., Walker, R. M., Bermingham, M. L., Morris, S. W., Clarke, T-K., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., Visscher, P. M., McIntosh, A. M., Evans, K. L., Deary, I. J. & Marioni, R. E., 30 Oct 2018, In : EBioMedicine.

    Research output: Contribution to journalArticle

  49. Genotype effects contribute to variation in longitudinal methylome patterns in older people

    Zhang, Q., Marioni, R., Robinson, M. R., Higham, J., Sproul, D., Wray, N. R., Deary, I., Mcrae, A. F. & Visscher, P. M., 22 Oct 2018, In : Genome Medicine. 10, 75, p. 1-11

    Research output: Contribution to journalArticle

  50. Epigenetic influences on aging: A longitudinal genome-wide methylation study in old Swedish twins

    Wang, Y., Karlsson, R., Lampa, E., Zhang, Q., Hedman, Å. K., Almgren, M., Almqvist, C., Mcrae, A. F., Marioni, R. E., Ingelsson, E., Visscher, P. M., Deary, I. J., Lind, L., Morris, T., Beck, S., Pedersen, N. L. & Hägg, S., 28 Sep 2018, In : Epigenetics.

    Research output: Contribution to journalArticle

  51. Epigenetic prediction of complex traits and death

    McCartney, D. L., Hillary, R. F., Stevenson, A. J., Ritchie, S. J., Walker, R. M., Zhang, Q., Morris, S. W., Bermingham, M. L., Campbell, A., Murray, A. D., Whalley, H. C., Gale, C. R., Porteous, D. J., Haley, C. S., McRae, A. F., Wray, N. R., Visscher, P. M., McIntosh, A. M., Evans, K. L., Deary, I. J. & 1 others, Marioni, R. E., 27 Sep 2018, In : Genome Biology. 19, 136.

    Research output: Contribution to journalArticle

  52. DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

    Story Jovanova, O., Nedeljkovic, I., Spieler, D., Walker, R. M., Liu, C., Luciano, M., Bressler, J., Brody, J., Drake, A. J., Evans, K. L., Gondalia, R., Kunze, S., Kuhnel, B., Lahti, J., Lemaitre, R. N., Marioni, R. E., Swenson, B., Himali, J. J., Wu, H., Li, Y. & 29 others, Mcrae, A. F., Russ, T. C., Stewart, J., Wang, Z., Zhang, G., Ladwig, K., Uitterlinden, A. G., Guo, X., Peters, A., Räikkönen, K., Starr, J. M., Waldenberger, M., Wray, N. R., Whitsel, E. A., Sotoodehnia, N., Seshadri, S., Porteous, D. J., Van Meurs, J., Mosley, T. H., McIntosh, A. M., Mendelson, M. M., Levy, D., Hou, L., Eriksson, J. G., Fornage, M., Deary, I. J., Baccarelli, A., Tiemeier, H. & Amin, N., Sep 2018, In : JAMA Psychiatry. 75, 9, p. 949-959

    Research output: Contribution to journalArticle

  53. Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 others, McIntosh, A. M., 30 Aug 2018, In : Nature Communications. 9, 1, p. 3578

    Research output: Contribution to journalArticle

  54. DNA methylation and the epigenetic clock in relation to physical frailty in older people: The Lothian Birth Cohort 1936

    Gale, C., Marioni, R., Harris, S., Starr, J. & Deary, I., 3 Aug 2018, In : Clinical Epigenetics. 10, 101, p. 1-8

    Research output: Contribution to journalArticle

  55. Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer’s disease

    Mccartney, D., Stevenson, A., Walker, R., Gibson, J., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H., Porteous, D., McIntosh, A., Evans, K., Deary, I. & Marioni, R., 21 Jun 2018, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  56. Brain age and other bodily ‘ages’: Implications for neuropsychiatry

    Cole, J. H., Marioni, R. E., Harris, S. E. & Deary, I. J., 11 Jun 2018, In : Molecular Psychiatry. 16 p.

    Research output: Contribution to journalArticle

  57. Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

    Qi, T., Wu, Y., Zeng, J., Zhang, F., Xue, A., Jiang, L., Zhu, Z., Kemper, K., Yengo, L., Zheng, Z., Marioni, R. E., Montgomery, G. W., Deary, I. J., Wray, N. R., Visscher, P. M., Mcrae, A. F. & Yang, J., 11 Jun 2018, In : Nature Communications. 9, 1, p. 1-12 2282.

    Research output: Contribution to journalArticle

  58. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P., Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., Mcintosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 29 May 2018, In : Nature Communications. 9, 1, p. 1-16 2098.

    Research output: Contribution to journalArticle

  59. GWAS on family history of Alzheimer’s disease

    Marioni, R. E., Harris, S. E., Zhang, Q., Mcrae, A. F., Hagenaars, S. P., Hill, W. D., Davies, G., Ritchie, C. W., Gale, C. R., Starr, J. M., Goate, A. M., Porteous, D. J., Yang, J., Evans, K. L., Deary, I. J., Wray, N. R. & Visscher, P. M., 18 May 2018, In : Translational Psychiatry. 8, 1

    Research output: Contribution to journalArticle

  60. Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M., Wigmore, E., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C., Breen, G., Deary, I. & 1 others, McIntosh, A., 16 Apr 2018, In : Nature Communications. 9, 1, p. 1-10 1470.

    Research output: Contribution to journalArticle

  61. Association of methylation signals with incident coronary heart disease in an epigenome-wide assessment of circulating tumor necrosis factor α

    Aslibekyan, S., Agha, G., Colicino, E., Do, A. N., Lahti, J., Ligthart, S., Marioni, R., Marzi, C., Mendelson, M. M., Tanaka, T., Wielscher, M., Absher, D. M., Ferrucci, L., Franco, O. H., Gieger, C., Grallert, H., Hernandez, D., Huan, T., Iurato, S., Joehanes, R. & 28 others, Just, A. C., Kunze, S., Lin, H., Liu, C., Meigs, J. B., vVan Meurs, J. B. J., Moore, A. Z., Peters, A., Räikkönen, K., Rathmann, W., Roden, M., Schramm, K., Schwartz, J. D., Starr, J., Uitterlinden, A. G., Vokonas, P., Waldenberger, M., Yao, C., Zhi, D., Baccarelli, A. A., Bandinelli, S., Deary, I., Dehghan, A., Eriksson, J., Herder, C., Järvelin, M-R., Levy, D. & Arnett, D. K., 4 Apr 2018, In : JAMA cardiology.

    Research output: Contribution to journalArticle

  62. Cognitive ability does not predict objectively measured sedentary behaviour: Evidence from three older cohorts

    Čukić, I., Shaw, R., Marioni, R., Chastin, S., Der, G., Dontje, M., Gill, J. M. R., Starr, J., Skelton, D. A., Radakovic, R., Cox, S., Dall, P., Gale, C. & Deary, I., 30 Mar 2018, In : Psychology and Aging. 33, 2, p. 288-296

    Research output: Contribution to journalArticle

  63. Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

    Wu, Y., Zeng, J., Zhang, F., Zhu, Z., Qi, T., Zheng, Z., Luke R, L-J., Marioni, R., Martin, N. G., Montgomery, G. W., Deary, I. J., Visscher, P., Mcrae, A. F. & Yang, J., 2 Mar 2018, In : Nature Communications. 9, p. 1-14 14 p., 918.

    Research output: Contribution to journalArticle

  64. GWAS of epigenetic aging rates in blood reveals a critical role for TERT

    Lu, A. T., Xue, L., Salfati, E. L., Chen, B. H., Ferrucci, L., Levy, D., Joehanes, R., Murabito, J. M., Kiel, D. P., Tsai, P-C., Yet, I., Bell, J. T., Mangino, M., Tanaka, T., Mcrae, A. F., Marioni, R. E., Visscher, P. M., Wray, N. R., Deary, I. J., Levine, M. E. & 19 others, Quach, A., Assimes, T. L., Tsao, P. S., Absher, D., Stewart, J. D., Li, Y., Reiner, A. P., Hou, L., Baccarelli, A. A., Whitsel, E. A., Aviv, A., Cardona, A., Day, F. R., Wareham, N. J., Perry, J. R. B., Ong, K. K., Raj, K., Lunetta, K. L. & Horvath, S., 26 Jan 2018, In : Nature Communications. 9, 1, 387.

    Research output: Contribution to journalArticle

  65. Meta-analysis of epigenome-wide association studies of cognitive abilities

    Marioni, R., Mcrae, A. F., Bressler, J., Colicino, E., Hannon, E., Li, S., prada, D., Smith, J. A., Trevisi, L., Tsai, P-C., Vojinovic, D., Simino, J., Levy, D., Liu, C., Mendelson, M. M., Satizabal, C. L., Yang, Q., Jhun, M. A., Kardia, S. L. R., Zhao, W. & 27 others, Bandinelli, S., Ferrucci, L., Hernandez, D., Singleton, A. B., Harris, S., Starr, J., Kiel, D. P., McLean, R. R., Just, A. C., Schwartz, J., Spiro, A., Vokonas, P., Amin, N., Ikram, M. A., Uitterlinden, A. G., van Meurs, J. B. J., Spector, T. D., Steves, C., Baccarelli, A. A., Bell, J. T., van Duijn, C. M., Fornage, M., Hsu, Y-H., Mill, J., Mosley, T. H., Seshadri, S. & Deary, I., 8 Jan 2018, In : Nature.

    Research output: Contribution to journalArticle

  66. The epigenetic clock and objectively measured sedentary and walking behaviour in older adults: The Lothian Birth Cohort 1936

    Gale, C., Marioni, R., Čukić, I., Chastin, S., Dall, P., Dontje, M., Skelton, D. A. & Deary, I., 8 Jan 2018, In : Clinical Epigenetics. 10, 4, 4.

    Research output: Contribution to journalArticle

  67. Brain age predicts mortality

    Cole, J., Ritchie, S. J., Bastin, M., Valdes Hernandez, M., Muñoz Maniega, S., Royle, N., Corley, J., Pattie, A., Harris, S., Zhang, Q., Wray, N. R., Redmond, P., Marioni, R., Starr, J., Cox, S., Wardlaw, J., Sharp, D. & Deary, I., 2018, In : Molecular Psychiatry. 23, p. 1385-1392 8 p.

    Research output: Contribution to journalArticle

  68. 2017
  69. Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

    Luciano, M., Hagenaars, S., Davies, G., Hill, W. D., Clarke, T-K., Shirali, M., Harris, S., Marioni, R., Liewald, D., Fawns-ritchie, C., Adams, M., Howard, D. M., Lewis, C. M., Gale, C., McIntosh, A. & Deary, I., 18 Dec 2017, In : Nature Genetics. 50, p. 6-11

    Research output: Contribution to journalLetter

  70. Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

    Harris, S. E., Riggio, V., Evenden, L., Gilchrist, T., Mccafferty, S., Murphy, L., Wrobel, N., Taylor, A. M., Corley, J., Pattie, A., Cox, S. R., Martin-ruiz, C., Prendergast, J., Starr, J. M., Marioni, R. E. & Deary, I. J., 1 Dec 2017, In : Aging. 9, 12, p. 2489-2503

    Research output: Contribution to journalArticle

  71. DNA methylation analysis identifies loci for blood pressure regulation

    Richard, M. A., Huan, T., Ligthart, S., Gondalia, R., Jhun, M. A., Brody, J. A., Irvin, M. R., Marioni, R., Shen, J., Tsai, P-C., Montasser, M. E., Jia, Y., Syme, C., Salfati, E. L., Boerwinkle, E., Guan, W., Mosley, T. H., Bressler, J., Morrison, A. C., Liu, C. & 31 others, Mendelson, M. M., Uitterlinden, A. G., van Meurs, J. B., Franco, O. H., Zhang, G., Li, Y., Stewart, J. D., Bis, J. C., Psaty, B. M., Chen, Y-D. I., Kardia, S. L. R., Zhao, W., Turner, S. T., Absher, D., Aslibekyan, S., Starr, J. M., McRae, A. F., Hou, L., Just, A. C., Schwartz, J. D., Vokonas, P. S., Menni, C., Spector, T. D., Shuldiner, A., Damcott, C. M., Rotter, J. I., Palmas, W., Liu, Y., Smith, J. A., Deary, I. J. & BIOS Consortium, 30 Nov 2017, In : American Journal of Human Genetics. 101, 6, p. 888-902

    Research output: Contribution to journalArticle

  72. Correction to: The epigenetic clock and telomere length are independently associated with chronological age and mortality

    Marioni, R. E., Harris, S. E., Shah, S., Mcrae, A. F., Von Zglinicki, T., Martin-ruiz, C., Wray, N. R., Visscher, P. M. & Deary, I. J., 27 Nov 2017, In : International Journal of Epidemiology.

    Research output: Contribution to journalArticle

  73. Phenotypic and Genetic Analysis of Cognitive Performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study

    Meijsen, J. J., Campbell, A., Hayward, C., Porteous, D. J., Deary, I. J., Marioni, R. E. & Nicodemus, K. K., Nov 2017, In : Genetic Epidemiology. 41, 7, p. 684-684 1 p.

    Research output: Contribution to journalMeeting abstract

  74. An epigenome-wide association study meta-analysis of educational attainment

    Karlsson Linnér, R., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davis, M., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S., Lahti, J., Mcrae, A. F., Mandaviya, P. R., Seppälä, I. & 50 others, Wang, Y., Baglietto, L., Binder, E. B., Harris, S., Hodge, M., Horvath, S., Hurme, M., Johannesson, M., Latvala, A., Mather, K. A., Medland, S. E., Metspalu, A., Milani, L., Milne, R. L., Pattie, A., Pedersen, N. L., Peters, A., Polidoro, S., Räikkönen, K., Severi, G., Starr, J. M., Stolk, L., Waldenberger, M., Eriksson, J. G., Esko, T., Franke, L., Gieger, C., Giles, G. G., Hägg, S., Jousilahti, P., Kaprio, J., Kähönen, M., Lehtimäki, T., Martin, N. G., Van Meurs, J. B. C., Ollikainen, M., Perola, M., Posthuma, D., Raitakari, O. T., Sachdev, P. S., Taskesen, E., Uitterlinden, A. G., Vineis, P., Wijmenga, C., Wright, M. J., Relton, C., Davey Smith, G., Deary, I. J., Koellinger, P. D. & Benjamin, D. J., 31 Oct 2017, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  75. Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

    Mandaviya, P. R., Joehanes, R., Aïssi, D., Kühnel, B., Marioni, R. E., Truong, V., Stolk, L., Beekman, M., Bonder, M. J., Franke, L., Gieger, C., Huan, T., Ikram, M. A., Kunze, S., Liang, L., Lindemans, J., Liu, C., McRae, A. F., Mendelson, M. M., Müller-Nurasyid, M. & 19 others, Peters, A., Slagboom, P. E., Starr, J. M., Trégouët, D-A., Uitterlinden, A. G., van Greevenbroek, M. M. J., van Heemst, D., van Iterson, M., Wells, P. S., Yao, C., Deary, I. J., Gagnon, F., Heijmans, B. T., Levy, D., Morange, P-E., Waldenberger, M., Heil, S. G., van Meurs, J. B. J. & CHARGE Consortium Epigenetics group and BIOS Consortium, 30 Oct 2017, In : PLoS ONE. 12, 10, p. 1-19 e0182472.

    Research output: Contribution to journalArticle

  76. New blood pressure–associated loci Identified in meta-analyses of 475 000 individuals

    Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-jensen, J., Brandslund, I., Farmaki, A., Fava, C., Ferreira, T., Herzig, K., Giri, A. & 121 others, Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Richard, M. A., Smith, J. A., Southam, L., Stančáková, A., Stirrups, K. E., Tragante, V., Tuomi, T., Tzoulaki, I., Varga, T. V., Weiss, S., Yiorkas, A. M., Young, R., Zhang, W., Barnes, M. R., Cabrera, C. P., Gao, H., Boehnke, M., Boerwinkle, E., Chambers, J. C., Connell, J. M., Christensen, C. K., De Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Dominiczak, A. F., Dörr, M., Joehanes, R., Edwards, T. L., Esko, T., Fornage, M., Franceschini, N., Franks, P. W., Gambaro, G., Groop, L., Hallmans, G., Hansen, T., Hayward, C., Heikki, O., Ingelsson, E., Tuomilehto, J., Jarvelin, M., Kardia, S. L. R., Karpe, F., Kooner, J. S., Lakka, T. A., Langenberg, C., Lind, L., Loos, R. J. F., Laakso, M., Mccarthy, M. I., Melander, O., Mohlke, K. L., Morris, A. P., Palmer, C. N. A., Pedersen, O., Polasek, O., Poulter, N. R., Province, M. A., Psaty, B. M., Ridker, P. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sever, P. J., Skaaby, T., Stafford, J. M., Starr, J. M., Van Der Harst, P., Van Der Meer, P., Van Duijn, C. M., Vergnaud, A., Gudnason, V., Wareham, N. J., Wilson, J. G., Willer, C. J., Witte, D. R., Zeggini, E., Saleheen, D., Butterworth, A. S., Danesh, J., Asselbergs, F. W., Wain, L. V., Ehret, G. B., Chasman, D. I., Caulfield, M. J., Elliott, P., Lindgren, C. M., Levy, D., Newton-cheh, C., Munroe, P. B. & Howson, J. M. M., 13 Oct 2017, In : Circulation. Cardiovascular genetics. 10, 5, p. e001778

    Research output: Contribution to journalArticle

  77. Identification, replication and characterization of epigenetic remodelling in the aging genome: A cross population analysis

    Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R., Deary, I. & Tan, Q., 15 Aug 2017, In : Scientific Reports. 7, p. 1-8 8183.

    Research output: Contribution to journalArticle

  78. Molecular genetic contributions to self-rated health

    Harris, S. E., Hagenaars, S. P., Davies, G., Hill, W. D., Liewald, D. CM., Ritchie, S. J., Marioni, R. E., Sudlow, C. LM., Wardlaw, J. M., McIntosh, A. M., Gale, C. R., Deary, I. J., METASTROKE consortium, International Consortium for Blood Pressure, CHARGE consortium Aging and Longevity Group & CHARGE consortium Cognitive Group, Jun 2017, In : International Journal of Epidemiology. 46, 3, p. 994-1009

    Research output: Contribution to journalArticle

  79. Cognitive Performance in Major Depressive Disorder in Generation Scotland: The Scottish Family Health Study (GS:SFHS)

    Meijsen, J., Campbell, A., McIntosh, A., Porteous, D., Deary, I., Marioni, R. & Nicodemus, K., 15 May 2017, In : Biological Psychiatry. 81, 10, p. S217-S217 1 p.

    Research output: Contribution to journalMeeting abstract

  80. Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

    Hägg, S., Zhan, Y., Karlsson, R., Gerritsen, L., Ploner, A., Van Der Lee, S. J., Broer, L., Deelen, J., Marioni, R. E., Wong, A., Lundquist, A., Zhu, G., Hansell, N. K., Sillanpää, E., Fedko, I. O., Amin, N. A., Beekman, M., De Craen, A. J. M., Degerman, S., Harris, S. E. & 25 others, Kan, K., Martin-ruiz, C. M., Montgomery, G. W., Adolfsson, A. N., Reynolds, C. A., Samani, N. J., Suchiman, H. E. D., Viljanen, A., Von Zglinicki, T., Wright, M. J., Hottenga, J., Boomsma, D. I., Rantanen, T., Kaprio, J. A., Nyholt, D. R., Martin, N. G., Nyberg, L., Adolfsson, R., Kuh, D., Starr, J. M., Deary, I. J., Slagboom, P. E., Van Duijn, C. M., Codd, V. & Pedersen, N. L., 18 Apr 2017, In : Translational Psychiatry. 7, 4, p. e1100

    Research output: Contribution to journalArticle

  81. Genetic stratification to identify risk groups for Alzheimer's disease

    Marioni, R., Campbell, A., Hagenaars, S., Nagy, R., Amador, C., Hayward, C., Porteous, D., Visscher, P. M. & Deary, I., 4 Mar 2017, In : Journal of Alzheimer's Disease. 57, 1, p. 275-283 8 p.

    Research output: Contribution to journalArticle

  82. Genetic prediction of male pattern baldness

    Hagenaars, S. P., Hill, W. D., Harris, S. E., Ritchie, S. J., Davies, G., Liewald, D. C., Gale, C. R., Porteous, D. J., Deary, I. J. & Marioni, R. E., 14 Feb 2017, In : PLoS Genetics. 13, 2, p. e1006594

    Research output: Contribution to journalArticle

  83. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

    de Vries, P. S., Sabater-Lleal, M., Chasman, D. I., Trompet, S., Ahluwalia, T. S., Teumer, A., Kleber, M. E., Chen, M-H., Wang, J. J., Attia, J. R., Marioni, R. E., Steri, M., Weng, L-C., Pool, R., Grossmann, V., Brody, J. A., Venturini, C., Tanaka, T., Rose, L. M., Oldmeadow, C. & 66 others, Mazur, J., Basu, S., Frånberg, M., Yang, Q., Ligthart, S., Hottenga, J. J., Rumley, A., Mulas, A., de Craen, A. J. M., Grotevendt, A., Taylor, K. D., Delgado, G. E., Kifley, A., Lopez, L. M., Berentzen, T. L., Mangino, M., Bandinelli, S., Morrison, A. C., Hamsten, A., Tofler, G., de Maat, M. P. M., Draisma, H. H. M., Lowe, G. D., Zoledziewska, M., Sattar, N., Lackner, K. J., Völker, U., McKnight, B., Huang, J., Holliday, E. G., McEvoy, M. A., Starr, J. M., Hysi, P. G., Hernandez, D. G., Guan, W., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Psaty, B. M., Uitterlinden, A. G., de Geus, E. J. C., Stott, D. J., Binder, H., Hofman, A., Franco, O. H., Rotter, J. I., Ferrucci, L., Spector, T. D., Deary, I. J., März, W., Greinacher, A., Wild, P. S., Cucca, F., Boomsma, D. I., Watkins, H., Tang, W., Ridker, P. M., Jukema, J. W., Scott, R. J., Mitchell, P., Hansen, T., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 20 Jan 2017, In : PLoS ONE. 12, 1, p. e0167742

    Research output: Contribution to journalArticle

  84. Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: A Mendelian randomization approach

    Mendelson, M. M., Marioni, R. E., Joehanes, R., Liu, C., Hedman, Å. K., Aslibekyan, S., Demerath, E. W., Guan, W., Zhi, D., Yao, C., Huan, T., Willinger, C., Chen, B. H., Courchesne, P., Multhaup, M. L., Irvin, M. R., Cohain, A., Schadt, E. E., Grove, M. L., Bressler, J. & 29 others, North, K. E., Sundstrom, J., Gustafsson, S., Shah, S., Mcrae, A. F., Harris, S. E., Gibson, J., Redmond, P., Corley, J., Murphy, L., Starr, J. M., Kleinbrink, E., Lipovich, L., Visscher, P. M., Wray, N. R., Krauss, R. M., Fallin, D., Feinberg, A. P., Absher, D. M., Fornage, M., Pankow, J. S., Lind, L., Fox, C. S., Ingelsson, E., Arnett, D. K., Boerwinkle, E., Liang, L., Levy, D. & Deary, I. J., 17 Jan 2017, In : PLoS Medicine. 14, 1, 30 p., e1002215.

    Research output: Contribution to journalArticle

  85. Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies

    Hedman, A. K., Mendelson, M. M., Marioni, R., Gustafsson, S., Joehanes, R., Irvin, M. R., Zhi, D., Sandling, J. K., Yao, C., Liu, C., Liang, L., Huan, T., Mcrae, A. F., Demissie, S., Shah, S., Starr, J., Adrienne Cupples, L., Deloukas, P., Spector, T. D., Sundström, J. & 6 others, Krauss, R. M., Arnett, D. K., Deary, I., Lind, L., Levy, D. & Ingelsson, E., 2017, In : Circulation. Cardiovascular genetics. 10, 1, e001487.

    Research output: Contribution to journalArticle

  86. 2016
  87. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

    Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M. M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., Joehanes, R., Guan, W., Brody, J. A., Elks, C., Marioni, R., Jhun, M. A., Agha, G., Bressler, J., Ward-Caviness, C. K., Chen, B. H., Huan, T., Bakulski, K. & 67 others, Salfati, E. L., Fiorito, G., Wahl, S., Schramm, K., Sha, J., Hernandez, D. G., Just, A. C., Smith, J. A., Sotoodehnia, N., Pilling, L. C., Pankow, J. S., Tsao, P. S., Liu, C., Zhao, W., Guarrera, S., Michopoulos, V. J., Smith, A. K., Peters, M. J., Melzer, D., Vokonas, P., Fornage, M., Prokisch, H., Bis, J. C., Chu, A. Y., Herder, C., Grallert, H., Yao, C., Shah, S., McRae, A. F., Lin, H., Horvath, S., Fallin, D., Hofman, A., Wareham, N. J., Wiggins, K. L., Feinberg, A. P., Starr, J. M., Visscher, P. M., Murabito, J. M., Kardia, S. L. R., Absher, D. M., Binder, E. B., Singleton, A. B., Bandinelli, S., Peters, A., Waldenberger, M., Matullo, G., Schwartz, J. D., Demerath, E. W., Uitterlinden, A. G., van Meurs, J. B. J., Franco, O. H., Chen, Y-D. I., Levy, D., Turner, S. T., Deary, I. J., Ressler, K. J., Dupuis, J., Ferrucci, L., Ong, K. K., Assimes, T. L., Boerwinkle, E., Koenig, W., Arnett, D. K., Baccarelli, A. A., Benjamin, E. J. & Dehghan, A., 12 Dec 2016, In : Genome Biology. 17, 255, 15 p.

    Research output: Contribution to journalArticle

  88. Genetic variants linked to education predict longevity

    Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., Davies, G., Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D. C., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J., Gale, C. R. & 13 others, Deary, I. J., Social Science Genetic Association Consortium, Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J. & Gale, C. V., 22 Nov 2016, In : Proceedings of the National Academy of Sciences (PNAS). 113, 47, p. 13366-13371 6 p.

    Research output: Contribution to journalArticle

  89. Molecular genetic contributions to social deprivation and household income in UK biobank

    Hill, W. D., Hagenaars, S. P., Marioni, R. E., Harris, S. E., Liewald, D. C. M., Davies, G., Okbay, A., McIntosh, A. M., Gale, C. R. & Deary, I. J., 21 Nov 2016, In : Current biology : CB. 26, 22, p. 3083-3089

    Research output: Contribution to journalArticle

  90. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

    Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., Smith, A. V. & 31 others, Vojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y-D. I., Cupples, L. A., de Jong, P. A., de Koning, H., de Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Wardlaw, J. M., Deary, I. J., Wilson, J. G. & CHARGE Consortium, 21 Nov 2016, In : Circulation. Cardiovascular genetics.

    Research output: Contribution to journalArticle

  91. A DNA methylation biomarker of alcohol consumption

    Liu, C., Marioni, R. E., Hedman, K. K., Pfeiffer, L., Tsai, P. C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kühnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C. & 53 others, Mendelson, M. M., Joehanes, R., Liang, L., Love, S. A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H., Strauch, K., Peters, A., Visscher, P. M., Wray, N. R., Guo, X., Wiggins, K. L., Smith, A. K., Binder, E. B., Ressler, K. J., Irvin, M. R., Absher, D. M., Hernandez, D., Ferrucci, L., Bandinelli, S., Lohman, K., Ding, J., Trevisi, L., Gustafsson, S., Sandling, J. H., Stolk, L., Uitterlinden, A. G., Yet, I., Castillo-Fernandez, J. E., Spector, T. D., Schwartz, J. D., Vokonas, P., Lind, L., Li, Y., Fornage, M., Arnett, D. K., Wareham, N. J., Sotoodehnia, N., Ong, K. K., van Meurs, J. B. J., Conneely, K. N., Baccarelli, A. A., Deary, I. J., Bell, J. T., North, K. E., Liu, Y., Waldenberger, M., London, S. J., Ingelsson, E. & Levy, D., 15 Nov 2016, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  92. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 31 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Harris, S. E., Liewald, D. C. M., Marioni, R., Polasek, O., Rudan, I., Deary, I. J., Starr, J. M., Morris, A. D., Porteous, D. J., Hayward, C. & CHARGE-Heart Failure Consortium, Oct 2016, In : Nature Genetics.

    Research output: Contribution to journalArticle

  93. DNA methylation-based measures of biological age: meta-analysis predicting time to death

    Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P-C., Roetker, N. S., Just, A. C., Demerath, E. W., Guan, W., Bressler, J., Fornage, M., Studenski, S., Vandiver, A. R., Moore, A. Z., Tanaka, T., Kiel, D. P., Liang, L., Vokonas, P., Schwartz, J. & 46 others, Lunetta, K. L., Murabito, J. M., Bandinelli, S., Hernandez, D. G., Melzer, D., Nalls, M., Pilling, L. C., Price, T. R., Singleton, A. B., Gieger, C., Holle, R., Kretschmer, A., Kronenberg, F., Kunze, S., Linseisen, J., Meisinger, C., Rathmann, W., Waldenberger, M., Visscher, P. M., Shah, S., Wray, N. R., McRae, A. F., Franco, O. H., Hofman, A., Uitterlinden, A. G., Absher, D., Assimes, T., Levine, M. E., Lu, A. T., Tsao, P. S., Hou, L., Manson, J. E., Carty, C. L., LaCroix, A. Z., Reiner, A. P., Spector, T. D., Feinberg, A. P., Levy, D., Baccarelli, A., van Meurs, J., Bell, J. T., Peters, A., Deary, I. J., Pankow, J. S., Ferrucci, L. & Horvath, S., 28 Sep 2016, In : Aging.

    Research output: Contribution to journalArticle

  94. Epigenetic signatures of cigarette smoking

    Deary, I., Joehanes, R., Just, A. C. & Marioni, R., 20 Sep 2016, In : Circulation. Cardiovascular genetics. 9, 5

    Research output: Contribution to journalArticle

  95. Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

    Pankratz, N., Schick, U. M., Zhou, Y., Zhou, W., Ahluwalia, T. S., Allende, M. L., Auer, P. L., Bork-Jensen, J., Brody, J. A., Chen, M. H., Clavo, V., Eicher, J. D., Grarup, N., Hagedorn, E. J., Hu, B., Hunker, K., Johnson, A. D., Leusink, M., Lu, Y., Lyytikainen, L. P. & 61 others, Manichaikul, A., Marioni, R., Nalls, M. A., Pazoki, R., Smith, A. V., Van Rooij, F. J. A., Yang, M. L., Zhang, X., Zhang, Y., Asselbergs, F. W., Boerwinkle, E., Borecki, I. B., Bottinger, E. P., Cushman, M., De Bakker, P. I. W., Deary, I., Dong, L., Feitosa, M. F., Floyd, J. S., Franceschini, N., Franco, O. H., Garcia, M. E., Grove, M. L., Gudnason, V., Hansen, T., Harris, T. B., Hofman, A., Jackson, R. D., Jia, J., Kahonen, M., Launer, L. J., Lehtimaki, T., Liewald, D., Linneberg, A., Liu, Y., Loos, R. J. F., Nguyen, V. M., Numans, M. E., Pedersen, O., Psaty, B. M., Raitakari, O. T., Rich, S. S., Rivadeneira, F., Di Sant, A. M. R., Rotter, J. I., Starr, J., Taylor, K. D., Thuesen, B. H., Tracy, R. P., Uitterlinden, A. G., Wang, J., Wang, J., Dehghan, A., Huo, Y., Adrienne Cupples, L., Wilson, J. G., Proia, R. L., Zon, L. I., O'Donnell, C. J., Reiner, A. P. & Ganesh, S. K., 1 Aug 2016, In : Nature Genetics. 48, 8, p. 867-876 10 p.

    Research output: Contribution to journalArticle

  96. Genome-wide analysis of over 106,000 individuals identifies 9 neuroticism-associated loci

    Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., Couvy-Duchesne, B. & 12 others, Graham, N., Mackay, D., Evans, J., Smith, B. H., Porteous, D. J., Medland, S. E., Martin, N. G., Holmans, P., McIntosh, A. M., Pell, J. P., Deary, I. J. & O'Donovan, M. C., Jun 2016, In : Molecular Psychiatry. 21, 6, p. 749-757

    Research output: Contribution to journalArticle

  97. Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

    Davies, G., Marioni, R. E., Liewald, D. C., Hill, W. D., Hagenaars, S. P., Harris, S. E., Ritchie, S. J., Luciano, M., Fawns-ritchie, C., Lyall, D., Cullen, B., Cox, S. R., Hayward, C., Porteous, D. J., Evans, J., Mcintosh, A. M., Gallacher, J., Craddock, N., Pell, J. P., Smith, D. J. & 2 others, Gale, C. R. & Deary, I. J., Jun 2016, In : Molecular Psychiatry. 21, 6, p. 758-767 10 p.

    Research output: Contribution to journalArticle

  98. Genome-wide association study identifies 74 loci associated with educational attainment

    LifeLines Cohort Study, 26 May 2016, In : Nature. 533, 7604, p. 539-542 4 p.

    Research output: Contribution to journalArticle

  99. The epigenetic clock and telomere length are independently associated with chronological age and mortality

    Marioni, R., Harris, S., Deary, I., Visscher, P. M., Wray, N. R., Mcrae, A. F., Von Zglinicki, T., Shah, S. & Martin-ruiz, C., 13 Apr 2016, In : International Journal of Epidemiology.

    Research output: Contribution to journalArticle

  100. Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

    Harris, S. E., Marioni, R. E., Martin-Ruiz, C., Pattie, A., Gow, A. J., Cox, S. R., Corley, J., von Zglinicki, T., Starr, J. M. & Deary, I. J., Mar 2016, In : Mechanisms of Ageing and Development. 154, p. 43-48 6 p.

    Research output: Contribution to journalArticle

  101. DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy

    Lin, Q., Weidner, C. I., Costa, I. G., Marioni, R. E., Ferreira, M. R. P., Deary, I. J. & Wagner, W., 25 Feb 2016, In : Aging. 8, 2, p. 394-401 8 p.

    Research output: Contribution to journalArticle

  102. Polygenic risk of ischemic stroke is associated with cognitive ability

    Harris, S. E., Malik, R., Marioni, R., Campbell, A., Seshadri, S., Worrall, B. B., Sudlow, C. L. M., Hayward, C., Bastin, M. E., Starr, J. M., Porteous, D. J., Wardlaw, J. M., Deary, I. J. & METASTROKE Consortium, 16 Feb 2016, In : Neurology. 86, 7, p. 611-618

    Research output: Contribution to journalArticle

  103. Assessing the genetic overlap between BMI and cognitive function

    Marioni, R. E., Yang, J., Dykiert, D., Mõttus, R., Campbell, A., Davies, G., Hayward, C., Porteous, D. J., Visscher, P. M., Deary, I. J. & CHARGE Cognitive Working Group, 9 Feb 2016, In : Molecular Psychiatry. 21, 10, p. 1477-1482

    Research output: Contribution to journalArticle

  104. Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

    Hagenaars, S. P., Harris, S. E., Davies, G., Hill, W. D., Liewald, D. C. M., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Cullen, B., Malik, R., Worrall, B. B., Sudlow, C. L. M., Wardlaw, J. M., Gallacher, J., Pell, J., McIntosh, A. M., Smith, D. J., Gale, C. R., Deary, I. J. & METASTROKE Consortium, International Consortium for Blood Pressure GWAS, 26 Jan 2016, In : Molecular Psychiatry. 21, 11, p. 1624-1632

    Research output: Contribution to journalArticle

  105. 2015
  106. A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration

    de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M-H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R. & 111 others, Yanek, L. R., Ahluwalia, T. S., Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L. M., Oldmeadow, C., Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Willemsen, G., Rumley, A., Fiorillo, E., de Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Lopez, L. M., Berentzen, T. L., Räikkönen, K., Mangino, M., Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D-A., Wright, A. F., Marten, J., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., de Maat, M. P. M., de Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M., Khaw, K-T., McKnight, B., Huang, J., Jenny, N. S., Holliday, E. G., Qi, L., McEvoy, M. G., Becker, D. M., Starr, J. M., Sarin, A-P., Hysi, P. G., Hernandez, D. G., Jhun, M. A., Campbell, H., Hamsten, A., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Koenig, W., Psaty, B. M., Haritunians, T., Liu, J., Palotie, A., Uitterlinden, A. G., Stott, D. J., Hofman, A., Franco, O. H., Polasek, O., Rudan, I., Morange, P-E., Wilson, J. F., Kardia, S. L. R., Ferrucci, L., Spector, T. D., Eriksson, J. G., Hansen, T., Deary, I. J., Becker, L. C., Scott, R. J., Mitchell, R., März, W., Wareham, N. J., Peters, A., Greinacher, A., Wild, P. S., Jukema, J. W., Boomsma, D. I., Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 10 Nov 2015, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

  107. Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium

    Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjørngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. S., Wannamethee, S. G., Lahti, J., Räikkönen, K. & 40 others, Palotie, A., Wong, A., Dalgård, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K. O., Kuh, D., Eriksson, J. G., Whincup, P. H., Mbarek, H., de Geus, E. J. C., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D. A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J. W., Power, C., Hyppönen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimäki, M., Smith, B. H., Hayward, C., Sørensen, T. I. A., Thuesen, B. H., Sattar, N., Morris, R. W., Romundstad, P. R., Munafò, M. R., Jarvelin, M-R. & Husemoen, L. L. N., 4 Nov 2015, In : Circulation. Cardiovascular genetics.

    Research output: Contribution to journalArticle

  108. Social activity, cognitive decline and dementia risk: a 20-year prospective cohort study

    Marioni, R. E., Proust-Lima, C., Amieva, H., Brayne, C., Matthews, F. E., Dartigues, J-F. & Jacqmin-Gadda, H., 24 Oct 2015, In : BMC Public Health. 15, 1, p. 1089

    Research output: Contribution to journalArticle

  109. Differential effects of the APOE e4 allele on different domains of cognitive ability across the life-course

    Generation Scotland, Hayward, C., Porteous, D. & Deary, I., 23 Sep 2015, In : European Journal of Human Genetics.

    Research output: Contribution to journalArticle

  110. Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

    Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 11 Aug 2015, In : BMJ Open. 5, 8, p. e008808

    Research output: Contribution to journalArticle

  111. Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations

    Shah, S., Bonder, M. J., Marioni, R. E., Zhu, Z., McRae, A. F., Zhernakova, A., Harris, S. E., Liewald, D., Henders, A. K., Mendelson, M. M., Liu, C., Joehanes, R., Liang, L., Levy, D., Martin, N. G., Starr, J. M., Wijmenga, C., Wray, N. R., Yang, J., Montgomery, G. W. & 4 others, Franke, L., Deary, I. J., Visscher, P. M. & BIOS Consortium, 2 Jul 2015, In : American Journal of Human Genetics.

    Research output: Contribution to journalArticle

  112. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

    Huffman, J. E., de Vries, P., Morrison, A. C., Sabater-Lleal, M., Kacprowski, T., Auer, P. L., Brody, J. A., Chasman, D. I., Chen, M-H., Guo, X., Lin, L-A., Marioni, R., muller-nurasyid, M., Yanek, L. R., Pankratz, N., Grove, M. L., de Maat, M. P. M., Cushman, M., Wiggins, K. L., Qi, L. & 47 others, Sennblad, B., Harris, S., Polašek, O., Riess, H., Rivadeneira, F., Rose, L. M., Goel, A., Taylor, K. D., Teumer, A., Uitterlinden, A. G., Vaidya, D., Yao, J., Tang, W., Levy, D., Waldenberger, M., Becker, D. M., Folsom, A. R., Giulianini, F., Greinacher, A., Hofman, A., Huang, C-C., Kooperberg, C., Silveira, A., Starr, J. M., Strauch, K., Strawbridge, R. J., Wright, A. F., McKnight, B., Franco, O. H., Zakai, N., Mathias, R. A., Psaty, B. M., Ridker, P. M., Tofler, G. H., Voelker, U., Watkins, H., Fornage, M., Hamsten, A., Deary, I., Boerwinkle, E., Koenig, W., Rotter, J. I., Hayward, C., Dehghan, A., Reiner, A. P., O'Donnell, C. J. & Smith, N. L., 23 Jun 2015, In : Blood.

    Research output: Contribution to journalArticle

  113. Current Versus Lifetime Depression, APOE Variation, and Their Interaction on Cognitive Performance in Younger and Older Adults

    Luciano, M., Pujals, A. M. F., Marioni, R. E., Campbell, A., Hayward, C., MacIntyre, D. J., Porteous, D. J., McIntosh, A. M., Deary, I. J. & Generation Scotland, 13 Jun 2015, In : Psychosomatic Medicine. 77, 5, p. 480-492 13 p.

    Research output: Contribution to journalArticle

  114. Exome Sequencing to Detect Rare Variants Associated With General Cognitive Ability: A Pilot Study

    Generation Scotland, 25 Apr 2015, In : Twin Research and Human Genetics. 18, 2, p. 117-125 9 p.

    Research output: Contribution to journalArticle

  115. DNA methylation age of blood predicts all-cause mortality in later life

    Marioni, R. E., Shah, S., McRae, A. F., Chen, B. H., Colicino, E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Feinberg, A. P., Fallin, M. D., Multhaup, M. L., Jaffe, A. E., Joehanes, R. & 11 others, Schwartz, J., Just, A. C., Lunetta, K. L., Murabito, J. M., Starr, J. M., Horvath, S., Baccarelli, A. A., Levy, D., Visscher, P. M., Wray, N. R. & Deary, I. J., 30 Jan 2015, In : Genome Biology. 16, 12 p., 25.

    Research output: Contribution to journalArticle

  116. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

    Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V., Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., van der Lee, S. J., Le Hellard, S., Liu, T., Marioni, R. E., Oldmeadow, C., Postmus, I., Smith, A. V., Smith, J. A., Thalamuthu, A., Thomson, R. & 31 others, Vitart, V., Wang, J., Yu, L., Zgaga, L., Zhao, W., Boxall, R., Harris, S. E., Hill, W. D., Liewald, D. C., Luciano, M., Adams, H., Ames, D., Amin, N., Amouyel, P., Assareh, A. A., Campbell, H., Corley, J., Pattie, A., Polasek, O., Redmond, P., Rotter, J. I., Taylor, K. D., Wright, A. F., Bennett, D. A., Hayward, C., Porteous, D. J., Rudan, I., Starr, J. M., Wilson, J. F., Deary, I. J. & Generation Scotland, 2015, In : Molecular Psychiatry. 20, 2, p. 183-192 10 p.

    Research output: Contribution to journalArticle

  117. Structural brain MRI trait polygenic score prediction of cognitive abilities

    Generation Scotland & SINAPSE Collaborative Grp, 2015, In : Twin Research and Human Genetics. 18, p. 738-745 8 p.

    Research output: Contribution to journalArticle

  118. The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

    Marioni, R. E., Shah, S., McRae, A. F., Ritchie, S. J., Muniz-Terrera, G., Harris, S. E., Gibson, J., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Taylor, A., Murphy, L., Starr, J. M., Horvath, S., Visscher, P. M., Wray, N. R. & Deary, I. J., 2015, In : International Journal of Epidemiology. 44, 4, p. 1388-1396

    Research output: Contribution to journalArticle

  119. 2014
  120. Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

    Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Asvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. S., Treur, J. L., Willemsen, G. & 44 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., Kisialiou, A., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Frayling, T., Nohr, E. A., Christiansen, L., Ohm Kyvik, K., Kuh, D., Watt, G., Eriksson, J., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 4 Dec 2014, In : PLoS Genetics. 10, 12, e1004799.

    Research output: Contribution to journalArticle

  121. Genetic and environmental exposures constrain epigenetic drift over the human life course

    Shah, S., Mcrae, A. F., Marioni, R. E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Starr, J. M., Wray, N. R., Deary, I. & Visscher, P. M., 1 Nov 2014, In : Genome Research. 24, 11, p. 1725-1733

    Research output: Contribution to journalArticle

  122. Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

    Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., Campbell, A., Engmann, J., Mirza, S. S., Loukola, A., Laatikainen, T., Partonen, T., Kaakinen, M., Ducci, F., Cavadino, A., Husemoen, L. L. N., Ahluwalia, T. S., Jacobsen, R. K., Skaaby, T., Ebstrup, J. F. & 42 others, Mortensen, E. L., Minica, C. C., Vink, J. M., Willemsen, G., Marques-Vidal, P., Dale, C. E., Amuzu, A., Lennon, L. T., Lahti, J., Palotie, A., Räikkönen, K., Wong, A., Paternoster, L., Wong, A. P-Y., Horwood, L. J., Murphy, M., Johnstone, E. C., Kennedy, M. A., Pausova, Z., Paus, T., Ben-Shlomo, Y., Nohr, E. A., Kuh, D., Kivimaki, M., Eriksson, J. G., Morris, R. W., Casas, J. P., Preisig, M., Boomsma, D. I., Linneberg, A., Power, C., Hyppönen, E., Veijola, J., Jarvelin, M-R., Korhonen, T., Tiemeier, H., Kumari, M., Porteous, D. J., Hayward, C., Romundstad, P. R., Smith, G. D. & Munafò, M. R., 7 Oct 2014, In : BMJ Open. 4, 10, p. e006141

    Research output: Contribution to journalArticle

  123. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

    Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., de Leeuw, C., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Smith, G. D., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 23 Sep 2014, In : Proceedings of the National Academy of Sciences (PNAS). 111, 38, p. 13790-13794 5 p.

    Research output: Contribution to journalArticle

  124. Molecular genetic contributions to socioeconomic status and intelligence

    Marioni, R. E., Davies, G., Hayward, C., Liewald, D., Kerr, S. M., Campbell, A., Luciano, M., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hastie, N. D., Wright, A. F., Porteous, D. J., Visscher, P. M. & Deary, I. J., 1 May 2014, In : Intelligence. 44, 100, p. 26-32

    Research output: Contribution to journalArticle

  125. Improving access to psychological therapies and older people: Findings from the Eastern Region

    Matthew Prina, A., Marioni, R. E., Hammond, G. C., Jones, P. B., Brayne, C. & Dening, T., May 2014, In : Behaviour Research and Therapy. 56, p. 75-81 7 p.

    Research output: Contribution to journalArticle

  126. The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability

    Marioni, R. E., Penke, L., Davies, G., Huffman, J. E., Hayward, C. & Deary, I. J., 22 Apr 2014, In : Proceedings of the Royal Society B-Biological Sciences. 281, 1781, 7 p., 20140117.

    Research output: Contribution to journalArticle

  127. C-reactive protein, APOE genotype and longitudinal cognitive change in an older population

    Lima, T. A. S., Adler, A. L., Minett, T., Matthews, F. E., Brayne, C., Marioni, R. E. & on behalf of the Medical Research Council Cognitive Function and Ageing Study, Mar 2014, In : Age and Ageing. 43, 2

    Research output: Contribution to journalArticle

  128. Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study

    Generation Scotland, Mar 2014, In : Behavior Genetics. 44, 2, p. 91-96 6 p.

    Research output: Contribution to journalArticle

  129. Cognitive lifestyle jointly predicts longitudinal cognitive decline and mortality risk

    Marioni, R. E., Proust-Lima, C., Amieva, H., Brayne, C., Matthews, F. E., Dartigues, J-F. & Jacqmin-Gadda, H., 28 Feb 2014, In : European Journal of Epidemiology. 9 p.

    Research output: Contribution to journalArticle

  130. Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

    Peloso, G. M., Auer, P. L., Bis, J. C., Voorman, A., Morrison, A. C., Stitziel, N. O., Brody, J. A., Khetarpal, S. A., Crosby, J. R., Fomage, M., Isaacs, A., Jakobsdottir, J., Feitosa, M. F., Davies, G., Huffman, J. E., Manichaikul, A., Davis, B., Lohman, K., Joon, A. Y., Smith, A. V. & 31 others, Grove, M. L., Zanoni, P., Redon, V., Demissie, S., Lawson, K., Peters, U., Carlson, C., Jackson, R. D., Ryckman, K. K., Mackey, R. H., Robinson, J. G., Siscovick, D. S., Schreiner, P. J., Mychaleckyj, J. C., Pankow, J. S., Holman, A., Uitterlinden, A. G., Harris, T. B., Taylor, K. D., Stafford, J. M., Reynolds, L. M., Marioni, R. E., Dehghan, A., Franco, O. H., Patele, A. P., Starr, J. M., Rudan, I., Hayward, C., Polasek, O., Deary, I. J. & NHLBI GO Exome Sequencing Project, 6 Feb 2014, In : American Journal of Human Genetics. 94, 2, p. 223-232 10 p.

    Research output: Contribution to journalArticle

  131. Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

    Hill, W. D., Davies, G., Van De Lagemaat, L. N., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S., Espeseth, T. & 7 others, Lundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C. & Deary, I. J., 7 Jan 2014, In : Translational Psychiatry. 4, 1, 8 p., 341.

    Research output: Contribution to journalArticle

  132. 2012
  133. Examining the influence of gender, education, social class and birth cohort on MMSE tracking over time: a population-based prospective cohort study

    Matthews, F., Marioni, R. & Brayne, C., 13 Aug 2012, In : BMC Geriatrics. 12, 1

    Research output: Contribution to journalArticle

  134. Active Cognitive Lifestyle Associates with Cognitive Recovery and a Reduced Risk of Cognitive Decline

    Marioni, R. E., van den Hout, A., Valenzuela, M. J., Brayne, C., Matthews, F. E. & MRC Cognitive Function Ageing, 2012, In : Journal of Alzheimer's Disease. 28, 1, p. 223-230 8 p.

    Research output: Contribution to journalArticle

  135. Active cognitive lifestyle is associated with positive cognitive health transitions and compression of morbidity from age sixty-five.

    Marioni, R., Valenzuela, M., Van Den Hout, A., Brayne, C. & Matthews, F., 2012, In : PLoS ONE. 7, 12, e50940.

    Research output: Contribution to journalArticle

  136. 2011
  137. The reliability of assigning individuals to cognitive states using the Mini Mental-State Examination: a population-based prospective cohort study

    Marioni, R. E., Chatfield, M., Brayne, C., Matthews, F. E. & Med Res Council, 6 Sep 2011, In : BMC Medical Research Methodology. 11, p. - 6 p., 127.

    Research output: Contribution to journalArticle

  138. Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts

    Marioni, R., Deary, I. J., Murray, G. D., Lowe, G. D. O., Strachan, M. W. J., Luciano, M., Houlihan, L., Gow, A. J., Harris, S. E., Rumley, A., Stewart, M. C., Fowkes, F. G. R. & Price, J. F., 1 Sep 2011, In : Behavior Genetics. 41, 5, p. 691-699 9 p.

    Research output: Contribution to journalArticle

  139. Chronic Kidney Disease: A Risk Factor for Dementia Onset: A Population-Based Study. The Osaki-Tajiri Project

    Sasaki, Y., Marioni, R. E., Kasai, M., Ishii, H., Yamaguchi, S. & Meguro, K., Jul 2011, In : Journal of the American Geriatrics Society. 59, 7, p. 1175-1181 7 p.

    Research output: Contribution to journalArticle

  140. The association between late-life cognitive test scores and retrospective informant interview data

    Marioni, R. E., Matthews, F. E., Brayne, C. & MRC Cognitive Function & Ageing St, Mar 2011, In : International Psychogeriatrics. 23, 2, p. 274-279 6 p.

    Research output: Contribution to journalArticle

  141. Cognitive function, dementia and type 2 diabetes mellitus in the elderly

    Strachan, M. W. J., Reynolds, R. M., Marioni, R. & Price, J. F., Feb 2011, In : Nature reviews endocrinology. 7, 2, p. 108-114 7 p.

    Research output: Contribution to journalLiterature review

  142. 2010
  143. Variation in the uric acid transporter gene (SLC2A9) and memory performance

    Houlihan, L. M., Wyatt, N. D., Harris, S. E., Hayward, C., Gow, A. J., Marioni, R. E., Strachan, M. W. J., Price, J. F., Starr, J., Wright, A. F. & Deary, I. J., 1 Jun 2010, In : Human Molecular Genetics. 19, 11, p. 2321-2330 10 p.

    Research output: Contribution to journalArticle

  144. Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study

    Marioni, R. E., Deary, I. J., Strachan, M. W., Lowe, G. D., Rumley, A., Murray, G. D. & Price, J. F., 1 May 2010, In : Age and Ageing. 39, 3, p. 354-359

    Research output: Contribution to journalArticle

  145. Associations between polymorphisms in five inflammation-related genes and cognitive ability in older persons

    Marioni, R. E., Deary, I., Murray, G. D., Fowkes, F. G. R. & Price, J. F., Apr 2010, In : Genes, Brain and Behavior. 9, 3, p. 348-352 5 p.

    Research output: Contribution to journalArticle

  146. Association Between Raised Inflammatory Markers and Cognitive Decline in Elderly People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

    Marioni, R., Strachan, M. W. J., Reynolds, R. M., Lowe, G. D. O., Mitchell, R. J., Fowkes, F. G. R., Frier, B. M., Lee, A. J., Butcher, I., Rumley, A., Murray, G. D., Deary, I. J. & Price, J., Mar 2010, In : Diabetes. 59, 3, p. 710-713 4 p.

    Research output: Contribution to journalArticle

  147. Genetic Variants Associated With Altered Plasma Levels of C-Reactive Protein are not Associated With Late-Life Cognitive Ability in Four Scottish Samples

    Marioni, R. E., Deary, I. J., Murray, G. D., Lowe, G. D. O., Rafnsson, S. B., Strachan, M. W. J., Luciano, M., Houlihan, L., Gow, A. J., Harris, S. E., Stewart, M. C., Rumley, A., Fowkes, F. G. R. & Price, J. F., 1 Jan 2010, In : Behavior Genetics. 40, 1, p. 3-11

    Research output: Contribution to journalArticle

  148. 2009
  149. Age-associated cognitive decline

    Deary, I. J., Corley, J., Gow, A. J., Harris, S., Houlihan, L., Marioni, R. E., Penke, L., Rafnsson, S. B. & Starr, J., 1 Dec 2009, In : British Medical Bulletin. 92, 1, p. 135-152

    Research output: Contribution to journalArticle

  150. Peripheral Levels of Fibrinogen, C-Reactive Protein, and Plasma Viscosity Predict Future Cognitive Decline in Individuals Without Dementia

    Marioni, R. E., Stewart, M. C., Murray, G. D., Deary, I. J., Fowkes, F. G. R., Lowe, G. D. O., Rumley, A. & Price, J. F., 1 Oct 2009, In : Psychosomatic Medicine. 71, 8, p. 901-906

    Research output: Contribution to journalArticle

  151. No association between cholinergic muscarinic receptor 2 (CHRM2) genetic variation and cognitive abilities in three independent samples

    Lind, P. A., Luciano, M., Horan, M. A., Marioni, R. E., Wright, M. J., Bates, T. C., Rabbitt, P., Harris, S. E., Davidson, Y., Deary, I. J., Gibbons, L., Pickles, A., Ollier, W., Pendleton, N., Price, J. F., Payton, A. & Martin, N. G., Sep 2009, In : Behavior Genetics. 39, 5, p. 513-523 11 p.

    Research output: Contribution to journalArticle

  152. Reverse Causation in the Association Between C-Reactive Protein and Fibrinogen Levels and Cognitive Abilities in an Aging Sample

    Luciano, M., Marioni, R. E., Gow, A. J., Starr, J. & Deary, I. J., May 2009, In : Psychosomatic Medicine. 71, 4, p. 404-409

    Research output: Contribution to journalArticle

  153. Inflammation and Cognition-A Causal Association?

    Marioni, R., Price, J., Deary, I., Murray, G. & Lowe, G., Apr 2009, In : Stroke. 40, 4, p. E131-E131 1 p.

    Research output: Contribution to journalMeeting abstract

  154. Association of KIBRA and memory

    Bates, T. C., Price, J., Harris, S., Marioni, R. E., Fowkes, F. G. R., Stewart, M., Murray, G. D., Whalley, L. J., Starr, J. & Deary, I. J., 2009, In : Neuroscience Letters. 458, 3, p. 140-143 4 p.

    Research output: Contribution to journalArticle

  155. 2008
  156. Is non-dipping of nocturnal blood pressure in type 2 diabetes associated with increased incidence of microalbuminuria?

    Heggie, A. J., Adamson, K. A., Marioni, R. E., Padfield, P. L. & Strachan, M. W., 1 May 2008, In : British Journal of Diabetes and Vascular Disease. 8, 3, p. 136-139

    Research output: Contribution to journalArticle

  157. Productivity cost model of the treatment of rheumatoid arthritis with abatacept

    Burton, W. N., Morrison, A., Yuan, Y., Li, T., Marioni, R. E. & Maclean, R., 1 Mar 2008, In : Journal of Medical Economics. 11, 1, p. 3-21

    Research output: Contribution to journalArticle

  158. 2007
  159. Serum angiotensin-converting enzyme and frequency of severe hypoglycaemia in Type 1 diabetes: does a relationship exist?

    Zammitt, N. N., Geddes, J., Warren, R. E., Marioni, R., Ashby, J. P. & Frier, B. M., Dec 2007, In : Diabetic Medicine. 24, 12, p. 1449-1454 6 p.

    Research output: Contribution to journalArticle