Edinburgh Research Explorer

Riccardo Marioni

Senior Research Fellow

  1. 2021
  2. DNA methylation of blood cells is associated with prevalent type 2 diabetes in a meta-analysis of four European cohorts

    Juvinao-quintero, D. L., Marioni, R. E., Ochoa-rosales, C., Russ, T. C., Deary, I. J., Van Meurs, J. B. J., Voortman, T., Hivert, M., Sharp, G. C., Relton, C. L. & Elliott, H. R., 23 Feb 2021, In: Clinical Epigenetics. 13, 1

    Research output: Contribution to journalArticlepeer-review

  3. Creating and validating a DNA methylation-based proxy for interleukin-6

    Stevenson, A. J., Gadd, D. A., Hillary, R. F., Mccartney, D. L., Campbell, A., Walker, R. M., Evans, K. L., Harris, S. E., Spires-jones, T. L., Mcrae, A. F., Visscher, P. M., Mcintosh, A. M., Deary, I. J. & Marioni, R. E., 17 Feb 2021, In: Journal of Gerontology: Medical Sciences.

    Research output: Contribution to journalArticlepeer-review

  4. Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci

    Ahluwalia, T. S., Prins, B. P., Abdollahi, M., Armstrong, N. J., Aslibekyan, S., Bain, L., Jefferis, B., Baumert, J., Beekman, M., Ben-shlomo, Y., Bis, J. C., Mitchell, B. D., De Geus, E., Delgado, G. E., Marek, D., Eriksson, J., Kajantie, E., Kanoni, S., Kemp, J. P., Lu, C. & 106 others, Marioni, R. E., Mclachlan, S., Milaneschi, Y., Nolte, I. M., Petrelis, A. M., Porcu, E., Sabater-lleal, M., Naderi, E., Seppälä, I., Shah, T., Singhal, G., Standl, M., Teumer, A., Thalamuthu, A., Thiering, E., Trompet, S., Ballantyne, C. M., Benjamin, E. J., Casas, J. P., Toben, C., Dedoussis, G., Deelen, J., Durda, P., Engmann, J., Feitosa, M. F., Grallert, H., Hammarstedt, A., Harris, S. E., Homuth, G., Hottenga, J., Jalkanen, S., Jamshidi, Y., Jawahar, M. C., Jess, T., Kivimaki, M., Kleber, M. E., Lahti, J., Liu, Y., Marques-vidal, P., Mellström, D., Mooijaart, S. P., Müller-nurasyid, M., Penninx, B., Revez, J. A., Rossing, P., Räikkönen, K., Sattar, N., Scharnagl, H., Sennblad, B., Silveira, A., Pourcain, B. S., Timpson, N. J., Trollor, J., Van Dongen, J., Van Heemst, D., Visvikis-siest, S., Vollenweider, P., Völker, U., Waldenberger, M., Willemsen, G., Zabaneh, D., Morris, R. W., Arnett, D. K., Baune, B. T., Boomsma, D. I., Chang, Y. C., Deary, I. J., Deloukas, P., Eriksson, J. G., Evans, D. M., Ferreira, M. A., Gaunt, T., Gudnason, V., Hamsten, A., Heinrich, J., Hingorani, A., Humphries, S. E., Jukema, J. W., Koeing, W., Kumari, M., Kutalik, Z., Lawlor, D. A., Lehtimäki, T., März, W., Mather, K., Naitza, S., Nauck, M., Ohlsson, C., Price, J. F., Raitakari, O., Rice, K., Sachdev, P. S., Slagboom, E., Sørensen, T. I. A., Spector, T., Stacey, D., Stathopoulou, M. G., Tanaka, T., Wannamethee, S. G., Whincup, P., Rotter, J. I., Dehghan, A., Boerwinkle, E., Psaty, B. M., Snieder, H. & Alizadeh, B. Z., 30 Jan 2021, In: Human Molecular Genetics.

    Research output: Contribution to journalArticlepeer-review

  5. Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles

    Generation Scotland, 4 Jan 2021, In: Genome Medicine.

    Research output: Contribution to journalArticlepeer-review

  6. 2020
  7. Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

    Green, C., Shen, X., Stevenson, A. J., Conole, E. L. S., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., Lawrie, S. M., Evans, K. L., Walker, R. M., Morris, S. W., Porteous, D. J., Wardlaw, J. M., Douglas Steele, J., Waiter, G. D., Sandu, A., Campbell, A., Marioni, R. E. & 4 others, Cox, S. R., Cavanagh, J., Mcintosh, A. M. & Whalley, H. C., 19 Nov 2020, In: Brain, Behavior, and Immunity.

    Research output: Contribution to journalArticlepeer-review

  8. Birth weight associations with DNA methylation differences in an adult population

    Madden, R., McCartney, D. L., Walker, R., Hillary, R., Bermingham, M., Rawlick, K., Morris, S., Campbell, A., Porteous, D. J., Deary, I., Evans, K. L., Hafferty, J., McIntosh, A. & Marioni, R. E., 20 Oct 2020, In: Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  9. Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture

    Zhang, Q., Sidorenko, J., Couvy-Duchesne, B., Marioni, R. E., Wright, M. J., Goate, A. M., Marcora, E., Huang, K., Porter, T., Laws, S., Sachdev, P. S., Mather, K. A., Armstrong, N. J., Thalamuthu, A., Brodaty, H., Yengo, L., Yang, J., Wray, N. R., Mcrae, A. F. & Visscher, P. M., 23 Sep 2020, In: Nature Communications. 4799 (2020).

    Research output: Contribution to journalArticlepeer-review

  10. Epigenome-wide analyses identify DNA methylation signatures of dementia risk

    Walker, R., Bermingham, M., Vaher, K., Morris, S., Clarke, T., Bretherick, A. D., Zeng, Y., Amador, C., Rawlik, K., Pandya, K., Hayward, C., Campbell, A., Porteous, D. J., McIntosh, A., Marioni, R. E. & Evans, K. L., 10 Aug 2020, In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.

    Research output: Contribution to journalArticlepeer-review

  11. Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden

    Hillary, R. F., Stevenson, A. J., McCartney, D. L., Campbell, A., Walker, R. M., Howard, D. M., Ritchie, C. W., Horvath, S., Hayward, C., McIntosh, A. M., Porteous, D. J., Deary, I. J., Evans, K. L. & Marioni, R. E., 31 Jul 2020, In: Clinical Epigenetics. 12, 12 p., 115.

    Research output: Contribution to journalArticlepeer-review

  12. Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

    Stevenson, A., McCartney, D., Hillary, R., Campbell, A., Morris, S., Bermingham, M., Walker, R., Evans, K. L., Boutin, T., Hayward, C., Mcrae, A. F., McColl, B., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R. E., 27 Jul 2020, In: Clinical Epigenetics. 12, 113.

    Research output: Contribution to journalArticlepeer-review

  13. Multi-method genome- and epigenome-wide studies of inflammatory protein levels in healthy older adults

    Hillary, R. F., Trejo-Banos, D., Kousathanas, A., McCartney, D. L., Harris, S. E., Stevenson, A. J., Patxot, M., Ojavee, S. E., Zhang, Q., Liewald, D. C., Ritchie, C. W., Evans, K. L., Tucker-Drob, E. M., Wray, N. R., McRae, A. F., Visscher, P. M., Deary, I. J., Robinson, M. R. & Marioni, R. E., 8 Jul 2020, In: Genome Medicine. 12, 60.

    Research output: Contribution to journalArticlepeer-review

  14. Blood DNA methylation sites predict death risk in a longitudinal study of 12,300 individuals

    Colicino, E., Marioni, R., Ward-Caviness, C., Gondalia, R., Guan, W., Chen, B. H., Tsai, P-C., Huan, T., Xu, G., Agha, G., Schwartz, J., Vokonas, P., Just, A. C., Starr, J., Mcrae, A. F., Wray, N., Visscher, P., Bressler, J., Zhang, W., Toshiko, T. & 29 others, Moore, A. Z., Pilling, L. C., Zhang, G., Stewart, J., Li, Y., Hou, L., Castillo-Fernandez, J., Spector, T. D., Kiel, D. P., Murabito, J. M., Liu, C., Mendelson, M., Assimes, T., Absher, D., Tsaho, P. S., Lu, A. T., Ferrucci, L., Wilson, R. P., Waldenberger, M., Prokisch, H., Bandinelli, S., Bell, J. T., Levy, D., Deary, I., Horvath, S., Pankow, J., Peters, A., Whitsel, E. A. & Baccarelli, A. A., Jul 2020, In: Aging. 12, 14, p. 14092—14124

    Research output: Contribution to journalArticlepeer-review

  15. Epigenetic prediction of major depressive disorder

    Barbu, M. C., Shen, X., Walker, R. M., Howard, D. M., Evans, K. L., Whalley, H. C., Porteous, D. J., Morris, S. W., Deary, I. J., Zeng, Y., Marioni, R. E., Clarke, T-K. & McIntosh, A. M., 10 Jun 2020, In: Molecular Psychiatry. N/A, p. 1-12 13 p.

    Research output: Contribution to journalArticlepeer-review

  16. Bayesian reassessment of the epigenetic architecture of complex traits

    Trejo Baños, D., McCartney, D. L., Patxot, M., Anchieri, L., Battram, T., Christiansen, C., Costeira, R., Walker, R. M., Morris, S. W., Campbell, A., Zhang, Q., Porteous, D. J., McRae, A. F., Wray, N. R., Visscher, P. M., Haley, C. S., Evans, K. L., Deary, I. J., McIntosh, A. M., Hemani, G. & 3 others, Bell, J. T., Marioni, R. E. & Robinson, M. R., 8 Jun 2020, In: Nature Communications. 11, 2865.

    Research output: Contribution to journalArticlepeer-review

  17. Ultra-high-throughput clinical proteomics reveals classifiers of COVID-19 infection

    Messner, C. B., Demichev, V., Wendisch, D., Michalick, L., White, M., Freiwald, A., Textoris-taube, K., Vernardis, S. I., Egger, A., Kreidl, M., Ludwig, D., Kilian, C., Agostini, F., Zelezniak, A., Thibeault, C., Pfeiffer, M., Hippenstiel, S., Hocke, A., Von Kalle, C., Campbell, A. & 12 others, Hayward, C., Porteous, D. J., Marioni, R. E., Langenberg, C., Lilley, K. S., Kuebler, W. M., Mülleder, M., Drosten, C., Witzenrath, M., Kurth, F., Sander, L. E. & Ralser, M., 2 Jun 2020, In: Cell Systems.

    Research output: Contribution to journalArticlepeer-review

  18. Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

    Li, S., Lund, J. B., Christensen, K., Baumbach, J., Mengel-From, J., Kruse, T. A., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R., Deary, I. & Tan, Q., 28 Apr 2020, In: Genome Medicine. 12, 39.

    Research output: Contribution to journalArticlepeer-review

  19. DNA methylation in APOE: The relationship with Alzheimer’s and with cardiovascular health

    Mur, J., McCartney, D. L., Walker, R., Campbell, A., Bermingham, M., Morris, S., Porteous, D., McIntosh, A., Deary, I., Evans, K. & Marioni, R., 27 Apr 2020, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 6, 1

    Research output: Contribution to journalArticlepeer-review

  20. DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936

    Seeboth, A., McCartney, D. L., Wang, Y., Hillary, R., Stevenson, A., Walker, R., Campbell, A., Evans, K., McIntosh, A., Hägg, S., Deary, I. & Marioni, R., 26 Mar 2020, In: Clinical Epigenetics. 12, 49

    Research output: Contribution to journalArticlepeer-review

  21. Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers

    Lund, J. B., Li, S., Baumbach, J., Christensen, K., Li, W., Mohammadnejad, A., Pattie, A., Marioni, R. E., Deary, I. J. & Tan, Q., 10 Mar 2020, In: Journal of Gerontology: Medical Sciences.

    Research output: Contribution to journalArticlepeer-review

  22. Epigenetic age acceleration and cognitive function in African-American adults in midlife: The Atherosclerosis Risk in Communities Study

    Bressler, J., Marioni, R. E., Walker, R. M., Xia, R., Gottesman, R. F., Windham, B. G., Grove, M. L., Guan, W., Pankow, J. S., Evans, K. L., Mcintosh, A. M., Deary, I. J., Mosley, T. H., Boerwinkle, E. & Fornage, M., Mar 2020, In: Journal of Gerontology: Medical Sciences. 75, 3, p. 473–480 glz245.

    Research output: Contribution to journalArticlepeer-review

  23. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In: Nature Communications. 11, 800.

    Research output: Contribution to journalArticlepeer-review

  24. Attitudes to ageing, biomarkers of ageing and mortality: The Lothian Birth Cohort 1936

    McLachlan, K., Cole, J., Harris, S., Marioni, R., Deary, I. & Gale, C., 28 Jan 2020, In: Journal of Epidemiology & Community Health.

    Research output: Contribution to journalArticlepeer-review

  25. 2019
  26. An epigenome-wide association study of sex-specific chronological ageing

    McCartney, D. L., Zhang, F., Hillary, R. F., Zhang, Q., Stevenson, A. J., Walker, R. M., Bermingham, M. L., Boutin, T., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., Hayward, C., Evans, K. L., Chandra, T., Deary, I. J., McIntosh, A. M., Yang, J., Visscher, P. M. & 2 others, McRae, A. F. & Marioni, R. E., 31 Dec 2019, In: Genome Biology. 12, 1.

    Research output: Contribution to journalArticlepeer-review

  27. An epigenetic predictor of death captures multi-modal measures of brain health

    Hillary, R. F., Stevenson, A. J., Cox, S. R., McCartney, D. L., Harris, S. E., Seeboth, A., Higham, J., Sproul, D., Taylor, A. M., Redmond, P., Corley, J., Pattie, A., del C. Valdés Hernández, M., Muñoz-Maniega, S., Bastin, M. E., Wardlaw, J. M., Horvath, S., Ritchie, C. W., Spires-Jones, T. L., McIntosh, A. M. & 3 others, Evans, K. L., Deary, I. J. & Marioni, R. E., 3 Dec 2019, In: Molecular Psychiatry. N/A, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  28. Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

    Hillary, R., McCartney, D. L., Harris, S., Stevenson, A., Seeboth, A., Zhang, Q., Liewald, D., Evans, K. L., Ritchie, C., Tucker-Drob, E. M., Wray, N. R., Mcrae, A. F., Visscher, P. M., Deary, I. & Marioni, R. E., Dec 2019, In: Nature Communications. 10, 3160.

    Research output: Contribution to journalArticlepeer-review

  29. Childhood intelligence attenuates the association between biological ageing and health outcomes in later life

    Stevenson, A., McCartney, D. L., Hillary, R., Redmond, P., Taylor, A., Zhang, Q., McRae, A., Spires-Jones, T., McIntosh, A., Deary, I. & Marioni, R., 28 Nov 2019, In: Translational Psychiatry. 9, 323.

    Research output: Contribution to journalArticlepeer-review

  30. DNA methylation Aging Clocks: Challenges & Recommendations

    Bell, C. G., Lowe, R., Adams, P. D., Baccarelli, A. A., Beck, S., Bell, J. T., Christensen, B. C., Gladyshev, V. N., Heijmans, B. T., Horvath, S., Ideker, T., Issa, J-P. J., Kelsey, K. T., Marioni, R., Reik, W., Relton, C. L., Schalkwyk, L. C., Teschendorff, A. E., Wagner, W., Zhang, K. & 1 others, Rakyan, V. K., 25 Nov 2019, In: Genome Biology.

    Research output: Contribution to journalArticlepeer-review

  31. A meta-analysis of genome-wide association studies of epigenetic age acceleration

    Gibson, J., Russ, T. C., Clarke, T-K., Howard, D. M., Hillary, R. F., Evans, K. L., Walker, R. M., Bermingham, M. L., Morris, S. W., Campbell, A., Hayward, C., Murray, A. D., Porteous, D. J., Horvath, S., Lu, A. T., McIntosh, A. M., Whalley, H. C. & Marioni, R. E., 18 Nov 2019, In: PLoS Genetics. 15, 11, e1008104.

    Research output: Contribution to journalArticlepeer-review

  32. Epigenome-wide association study of leukocyte telomere length

    Lee, Y., Sun, D., Ori, A. P. S., Lu, A. T., Seeboth, A., Harris, S., Deary, I., Marioni, R., Soerensen, M., Mengel-From, J., Hjelmborg, J., Christensen, K., Wilson, J. G., Levy, D., Reiner, A. P., Chen, W., Li, S., Harris, J. R., Magnus, P., Aviv, A. & 2 others, Jugessur, A. & Horvath, S., 26 Aug 2019, In: Aging.

    Research output: Contribution to journalArticlepeer-review

  33. Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

    Zhang, Q., Vallerga, C. L., Walker, R. M., Lin, T., Henders, A. K., Montgomery, G. W., He, J., Fan, D., Fowdar, J., Kennedy, M., Pitcher, T., Pearson, J., Halliday, G., Kwok, J. B., Hickie, I., Lewis, S., Anderson, T., Silburn, P. A., Mellick, G. D., Harris, S. E. & 13 others, Redmond, P., Murray, A. D., Porteous, D. J., Haley, C. S., Evans, K. L., Mcintosh, A. M., Yang, J., Gratten, J., Marioni, R. E., Wray, N. R., Deary, I. J., Mcrae, A. F. & Visscher, P. M., 23 Aug 2019, In: Genome Medicine. 11, 1, 54.

    Research output: Contribution to journalArticlepeer-review

  34. Age-related clonal haematopoiesis is associated with increased epigenetic age

    Robertson, N. A., Hillary, R. F., McCartney, D. L., Terradas-Terradas, M., Higham, J., Sproul, D., Deary, I. J., Kirschner, K., Marioni, R. E. & Chandra, T., 19 Aug 2019, In: Current Biology. 29, 16, p. R786-R787

    Research output: Contribution to journalArticlepeer-review

  35. DNA methylation-based estimator of telomere length

    Lu, A. T., Seeboth, A., Tsai, P-C., Sun, D., Quach, A., Reiner, A. P., Kooperberg, C., Ferrucci, L., Hou, L., Baccarelli, A. A., Li, Y., Harris, S. E., Corley, J., Taylor, A., Deary, I. J., Stewart, J. D., Whitsel, E. A., Assimes, T. L., Chen, W., Li, S. & 7 others, Mangino, M., Bell, J. T., Wilson, J., Aviv, A., Marioni, R. E., Raj, K. & Horvath, S., 18 Aug 2019, In: Aging. 11

    Research output: Contribution to journalArticlepeer-review

  36. Correction: GWAS on family history of Alzheimer’s disease

    Marioni, R. E., Harris, S. E., Zhang, Q., Mcrae, A. F., Hagenaars, S. P., Hill, W. D., Davies, G., Ritchie, C. W., Gale, C. R., Starr, J. M., Goate, A. M., Porteous, D. J., Yang, J., Evans, K. L., Deary, I. J., Wray, N. R. & Visscher, P. M., 6 Jun 2019, In: Translational Psychiatry. 9, 1

    Research output: Contribution to journalComment/debate

  37. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S-C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L-P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 May 2019, In: Nature Communications. 10, 1, p. 2068

    Research output: Contribution to journalArticle

  38. Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits

    Grotzinger, A., Rhemtulla, M., Vlaming, R. D., Ritchie, S. J., Mallard, T. T., Hill, W. D., Hill, F., Marioni, R., McIntosh, A., Deary, I., Koellinger, P. D., Harden, K. P., Nivard, M. G. & Tucker-Drob, E. M., May 2019, In: Nature Human Behaviour. 3, 5, p. 513-525

    Research output: Contribution to journalArticlepeer-review

  39. Examining the Impact of Imputation Errors on Fine-Mapping Using DNA Methylation QTL as a Model Trait

    Chundru, V. K., Marioni, R. E., Prendergast, J. G. D., Vallerga, C. L., Lin, T., Berveridge, A. J., Consortium, S., Gratten, J., Hume, D. A., Deary, I. J., Wray, N. R., Visscher, P. M. & McRae, A. F., 30 Apr 2019, In: Genetics.

    Research output: Contribution to journalArticlepeer-review

  40. Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

    Howard, D. M., Adams, M. J., Clarke, T-K., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 20 others, Berger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & McIntosh, A. M., 31 Mar 2019, In: Nature Neuroscience. 22, 3, p. 343–352 10 p.

    Research output: Contribution to journalArticlepeer-review

  41. An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort

    Hamilton, O., Zhang, Q., Mcrae, A. F., Walker, R., Morris, S., Redmond, P., Campbell, A., Murray, A., Porteous, D., Evans, K., McIntosh, A., Deary, I. & Marioni, R., 6 Mar 2019, In: International Journal of Obesity.

    Research output: Contribution to journalArticlepeer-review

  42. A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence

    Hill, W. D., Marioni, R. E., Maghzian, O., Ritchie, S. J., Hagenaars, S. P., McIntosh, A. M., Gale, C. R., Davies, G. & Deary, I. J., 28 Feb 2019, In: Molecular Psychiatry. 24, 2, p. 169-181 13 p.

    Research output: Contribution to journalArticlepeer-review

  43. Age‐dependent DNA methylation patterns on the Y chromosome in elderly males

    Lund, J., Li, S., Christensen, K., Mengel-From, J., Soerensen, M., Marioni, R., Starr, J., Pattie, A., Deary, I., Baumbach, J. & Tan, Q., 21 Feb 2019, In: Aging Cell.

    Research output: Contribution to journalArticlepeer-review

  44. Polygenic predictors of age-related decline in cognitive ability

    Ritchie, S. J., Hill, W. D., Marioni, R., Davies, G., Hagenaars, S., Harris, S., Cox, S., Taylor, A., Corley, J., Pattie, A., Redmond, P., Starr, J. & Deary, I., 13 Feb 2019, In: Molecular Psychiatry. p. 1-15

    Research output: Contribution to journalArticlepeer-review

  45. Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identity

    Olova, N., Simpson, D. J., Marioni, R. E. & Chandra, T., 1 Feb 2019, In: Aging Cell. 18, 1, e12877.

    Research output: Contribution to journalArticlepeer-review

  46. DNA methylome profiling of all-cause mortality in comparison with age-associated methylation patterns

    Lund, J., Li, S., Baumbach, J., Svane, A. M., Hjelmborg, J., Christiansen, L., Christensen, K., Redmond, P., Marioni, R., Deary, I. & Tan, Q., Feb 2019, In: Clinical Epigenetics. 11, 23, p. 1-8

    Research output: Contribution to journalArticlepeer-review

  47. Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

    Erzurumluoglu, A. M., Liu, M., Jackson, V. E., Barnes, D. R., Datta, G., Melbourne, C. A., Young, R. D., Batini, C., Surendran, P., Jiang, T., Adnan, S. D., Afaq, S., Agrawal, A., Altmaier, E., Antoniou, A. C., Asselbergs, F. W., Baumbach, C., Bierut, L., Bertelsen, S., Boehnke, M. & 156 others, Bots, M. L., Brazel, D. M., Chambers, J. C., Chang-claude, J., Chen, C., Corley, J., Chou, Y., David, S. P., De Boer, R. A., De Leeuw, C. A., Dennis, J. G., Dominiczak, A. F., Dunning, A. M., Easton, D. F., Eaton, C., Elliott, P., Evangelou, E., Faul, J. D., Foroud, T., Goate, A., Gong, J., Grabe, H. J., Haessler, J., Haiman, C., Hallmans, G., Hammerschlag, A. R., Harris, S. E., Hattersley, A., Heath, A., Hsu, C., Iacono, W. G., Kanoni, S., Kapoor, M., Kaprio, J., Kardia, S. L., Karpe, F., Kontto, J., Kooner, J. S., Kooperberg, C., Kuulasmaa, K., Laakso, M., Lai, D., Langenberg, C., Le, N., Lettre, G., Loukola, A., Luan, J., Madden, P. A. F., Mangino, M., Marioni, R. E., Marouli, E., Marten, J., Martin, N. G., Mcgue, M., Michailidou, K., Mihailov, E., Moayyeri, A., Moitry, M., Müller-nurasyid, M., Naheed, A., Nauck, M., Neville, M. J., Nielsen, S. F., North, K., Perola, M., Pharoah, P. D. P., Pistis, G., Polderman, T. J., Posthuma, D., Poulter, N., Qaiser, B., Rasheed, A., Reiner, A., Renström, F., Rice, J., Rohde, R., Rolandsson, O., Samani, N. J., Samuel, M., Schlessinger, D., Scholte, S. H., Scott, R. A., Sever, P., Shao, Y., Shrine, N., Smith, J. A., Starr, J. M., Stirrups, K., Stram, D., Stringham, H. M., Tachmazidou, I., Tardif, J., Thompson, D. J., Tindle, H. A., Tragante, V., Trompet, S., Turcot, V., Tyrrell, J., Vaartjes, I., Van Der Leij, A. R., Van Der Meer, P., Varga, T. V., Verweij, N., Völzke, H., Wareham, N. J., Warren, H. R., Weir, D. R., Weiss, S., Wetherill, L., Yaghootkar, H., Yavas, E., Jiang, Y., Chen, F., Zhan, X., Zhang, W., Zhao, W., Zhao, W., Zhou, K., Amouyel, P., Blankenberg, S., Caulfield, M. J., Chowdhury, R., Cucca, F., Deary, I. J., Deloukas, P., Di Angelantonio, E., Ferrario, M., Ferrières, J., Franks, P. W., Frayling, T. M., Frossard, P., Hall, I. P., Hayward, C., Jansson, J., Jukema, J. W., Kee, F., Männistö, S., Metspalu, A., Munroe, P. B., Nordestgaard, B. G., Palmer, C. N. A., Salomaa, V., Sattar, N., Spector, T., Strachan, D. P., Van Der Harst, P., Zeggini, E., Saleheen, D., Butterworth, A. S., Wain, L. V., Abecasis, G. R., Danesh, J., Tobin, M. D., Vrieze, S., Liu, D. J. & Howson, J. M. M., 7 Jan 2019, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  48. Tracking the epigenetic clock across the human life course: A meta-analysis of longitudinal cohort data

    Marioni, R., Suderman, M. J., Chen, B. H., Horvath, S., Bandinelli, S., Morris, T. J., Becker, S., Ferrucci, L., Pedersen, N. L., Relton, C. L., Deary, I. & Hägg, S., Jan 2019, In: Journal of Gerontology: Medical Sciences. 74, 1, p. 1-5 gly060.

    Research output: Contribution to journalArticlepeer-review

  49. 2018
  50. Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

    Stevenson, A., McCartney, D. L., Harris, S., Taylor, A., Redmond, P., Starr, J., Zhang, Q., McRae, A. F., Wray, N. R., Spires-Jones, T., McColl, B., McIntosh, A., Deary, I. & Marioni, R., 20 Dec 2018, In: Clinical Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  51. Identification of 55,000 Replicated DNA Methylation QTL

    McRae, A. F., Marioni, R. E., Shah, S., Yang, J., Powell, J. E., Harris, S. E., Gibson, J., Henders, A. K., Bowdler, L., Painter, J. N., Murphy, L., Martin, N. G., Starr, J. M., Wray, N. R., Deary, I. J., Visscher, P. M. & Montgomery, G. W., 4 Dec 2018, In: Scientific Reports. 8, 1, p. 1-9 17605.

    Research output: Contribution to journalArticlepeer-review

  52. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

    Franceschini, N., Giambartolomei, C., De Vries, P. S., Finan, C., Bis, J. C., Huntley, R. P., Lovering, R. C., Tajuddin, S. M., Winkler, T. W., Graff, M., Kavousi, M., Dale, C., Smith, A. V., Hofer, E., Van Leeuwen, E. M., Nolte, I. M., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N. & 137 others, Franzén, O., Joshi, P. K., Noordam, R., Marioni, R. E., Hwang, S., Musani, S. K., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, A. B., Hofman, A., Teumer, A., Cox, A. J., Uitterlinden, A. G., Wong, A., Smit, A. J., Newman, A. B., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, B. W., Langefeld, C. D., Wassel, C. L., Tzourio, C., Fava, C., Baldassarre, D., O’leary, D. H., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, E. E., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, H. S., Deary, I. J., Jukema, J. W., De Graaf, J., Price, J., Pott, J., Hopewell, J. C., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, K. D., Dhana, K., Kiemeney, L. A. L. M., Lind, L., Raffield, L. M., Launer, L. J., Holdt, L. M., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, M. A., Melander, O., Raitakari, O., Franco, O. H., Rueda-ochoa, O. L., Roussos, P., Whincup, P. H., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., De Mutsert, R., Morris, R. W., Strawbridge, R. J., Wannamethee, S. G., Hägg, S., Shah, S., Mclachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, S. R., Ring, S., Harris, T. B., Lehtimäki, T., Galesloot, T. E., Shah, T., De Faire, U., Plagnol, V., Rosamond, W. D., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., Dehghan, A., Seldenrijk, A., Morrison, A. C., Hamsten, A., Psaty, B. M., Van Duijn, C. M., Lawlor, D. A., Mook-kanamori, D. O., Bowden, D. W., Schmidt, H., Wilson, J. G., Rotter, J. I., Wardlaw, J. M., Deanfield, J., Halcox, J., Lyytikäinen, L., Loeffler, M., Evans, M. K., Debette, S., Humphries, S. E., Völker, U., Gudnason, V., Hingorani, A. D., Björkegren, J. L. M., Casas, J. P. & O’donnell, C. J., 3 Dec 2018, In: Nature Communications. 9, 1, 5141.

    Research output: Contribution to journalArticlepeer-review

  53. Association of facial ageing with DNA methylation and epigenetic age predictions

    Marioni, R. E., Belsky, D. W., Deary, I. J. & Wagner, W., 8 Nov 2018, In: Clinical Epigenetics. 10, 140, p. 1-3

    Research output: Contribution to journalShort surveypeer-review

  54. Epigenetic signatures of starting and stopping smoking

    McCartney, D. L., Stevenson, A. J., Hillary, R. F., Walker, R. M., Bermingham, M. L., Morris, S. W., Clarke, T-K., Campbell, A., Murray, A. D., Whalley, H. C., Porteous, D. J., Visscher, P. M., McIntosh, A. M., Evans, K. L., Deary, I. J. & Marioni, R. E., 1 Nov 2018, In: EBioMedicine. 37, p. 214-220

    Research output: Contribution to journalArticlepeer-review

  55. Genome-wide association analyses of >200,000 individuals identify 58 genetic loci for chronic inflammation and highlights pathways that link inflammation and complex disorders

    Ligthart, S., Vaez, A., Võsa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Schraut, K. E., Joshi, P., Campbell, H., Wilson, J., Marioni, R. & Deary, I., 1 Nov 2018, In: American Journal of Human Genetics. 103, 5, p. 691-706

    Research output: Contribution to journalArticlepeer-review

  56. Genotype effects contribute to variation in longitudinal methylome patterns in older people

    Zhang, Q., Marioni, R., Robinson, M. R., Higham, J., Sproul, D., Wray, N. R., Deary, I., Mcrae, A. F. & Visscher, P. M., 22 Oct 2018, In: Genome Medicine. 10, 75, p. 1-11

    Research output: Contribution to journalArticlepeer-review

  57. DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

    Story Jovanova, O., Nedeljkovic, I., Spieler, D., Walker, R. M., Liu, C., Luciano, M., Bressler, J., Brody, J., Drake, A. J., Evans, K. L., Gondalia, R., Kunze, S., Kuhnel, B., Lahti, J., Lemaitre, R. N., Marioni, R. E., Swenson, B., Himali, J. J., Wu, H., Li, Y. & 29 others, McRae, A. F., Russ, T. C., Stewart, J., Wang, Z., Zhang, G., Ladwig, K-H., Uitterlinden, A. G., Guo, X., Peters, A., Räikkönen, K., Starr, J. M., Waldenberger, M., Wray, N. R., Whitsel, E. A., Sotoodehnia, N., Seshadri, S., Porteous, D. J., Van Meurs, J., Mosley, T. H., McIntosh, A. M., Mendelson, M. M., Levy, D., Hou, L., Eriksson, J. G., Fornage, M., Deary, I. J., Baccarelli, A., Tiemeier, H. & Amin, N., 30 Sep 2018, In: JAMA Psychiatry. 75, 9, p. 949-959 11 p.

    Research output: Contribution to journalArticlepeer-review

  58. Epigenetic influences on aging: A longitudinal genome-wide methylation study in old Swedish twins

    Wang, Y., Karlsson, R., Lampa, E., Zhang, Q., Hedman, Å. K., Almgren, M., Almqvist, C., Mcrae, A. F., Marioni, R. E., Ingelsson, E., Visscher, P. M., Deary, I. J., Lind, L., Morris, T., Beck, S., Pedersen, N. L. & Hägg, S., 28 Sep 2018, In: Epigenetics.

    Research output: Contribution to journalArticlepeer-review

  59. Epigenetic prediction of complex traits and death

    McCartney, D. L., Hillary, R. F., Stevenson, A. J., Ritchie, S. J., Walker, R. M., Zhang, Q., Morris, S. W., Bermingham, M. L., Campbell, A., Murray, A. D., Whalley, H. C., Gale, C. R., Porteous, D. J., Haley, C. S., McRae, A. F., Wray, N. R., Visscher, P. M., McIntosh, A. M., Evans, K. L., Deary, I. J. & 1 others, Marioni, R. E., 27 Sep 2018, In: Genome Biology. 19, 136.

    Research output: Contribution to journalArticlepeer-review

  60. Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 others, McIntosh, A. M., 30 Aug 2018, In: Nature Communications. 9, 1, p. 3578

    Research output: Contribution to journalArticlepeer-review

  61. DNA methylation and the epigenetic clock in relation to physical frailty in older people: The Lothian Birth Cohort 1936

    Gale, C., Marioni, R., Harris, S., Starr, J. & Deary, I., 3 Aug 2018, In: Clinical Epigenetics. 10, 101, p. 1-8

    Research output: Contribution to journalArticlepeer-review

  62. Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer’s disease

    Mccartney, D., Stevenson, A., Walker, R., Gibson, J., Morris, S. W., Campbell, A., Murray, A. D., Whalley, H., Porteous, D., McIntosh, A., Evans, K., Deary, I. & Marioni, R., 21 Jun 2018, In: Alzheimer's & Dementia.

    Research output: Contribution to journalArticlepeer-review

  63. Brain age and other bodily ‘ages’: Implications for neuropsychiatry

    Cole, J. H., Marioni, R. E., Harris, S. E. & Deary, I. J., 11 Jun 2018, In: Molecular Psychiatry. 16 p.

    Research output: Contribution to journalArticlepeer-review

  64. Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

    Qi, T., Wu, Y., Zeng, J., Zhang, F., Xue, A., Jiang, L., Zhu, Z., Kemper, K., Yengo, L., Zheng, Z., Marioni, R. E., Montgomery, G. W., Deary, I. J., Wray, N. R., Visscher, P. M., Mcrae, A. F. & Yang, J., 11 Jun 2018, In: Nature Communications. 9, 1, p. 1-12 2282.

    Research output: Contribution to journalArticlepeer-review

  65. Brain age predicts mortality

    Cole, J. H., Ritchie, S. J., Bastin, M. E., Valdés Hernández, M. C., Muñoz Maniega, S., Royle, N., Corley, J., Pattie, A., Harris, S. E., Zhang, Q., Wray, N. R., Redmond, P., Marioni, R. E., Starr, J. M., Cox, S. R., Wardlaw, J. M., Sharp, D. J. & Deary, I. J., 31 May 2018, In: Molecular Psychiatry. 23, p. 1385-1392 8 p.

    Research output: Contribution to journalArticlepeer-review

  66. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P., Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., Mcintosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 29 May 2018, In: Nature Communications. 9, 1, 2098.

    Research output: Contribution to journalArticlepeer-review

  67. GWAS on family history of Alzheimer’s disease

    Marioni, R. E., Harris, S. E., Zhang, Q., McRae, A. F., Hagenaars, S. P., Hill, W. D., Davies, G., Ritchie, C. W., Gale, C. R., Starr, J. M., Goate, A. M., Porteous, D. J., Yang, J., Evans, K. L., Deary, I. J., Wray, N. R. & Visscher, P. M., 18 May 2018, In: Translational Psychiatry. 8, 99.

    Research output: Contribution to journalArticlepeer-review

  68. Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., 23andMe Research Team, Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G. & 2 others, Deary, I. J. & McIntosh, A. M., 16 Apr 2018, In: Nature Communications. 9, 1, p. 1-10 10 p., 1470.

    Research output: Contribution to journalArticlepeer-review

  69. Association of methylation signals with incident coronary heart disease in an epigenome-wide assessment of circulating tumor necrosis factor α

    Aslibekyan, S., Agha, G., Colicino, E., Do, A. N., Lahti, J., Ligthart, S., Marioni, R., Marzi, C., Mendelson, M. M., Tanaka, T., Wielscher, M., Absher, D. M., Ferrucci, L., Franco, O. H., Gieger, C., Grallert, H., Hernandez, D., Huan, T., Iurato, S., Joehanes, R. & 28 others, Just, A. C., Kunze, S., Lin, H., Liu, C., Meigs, J. B., vVan Meurs, J. B. J., Moore, A. Z., Peters, A., Räikkönen, K., Rathmann, W., Roden, M., Schramm, K., Schwartz, J. D., Starr, J., Uitterlinden, A. G., Vokonas, P., Waldenberger, M., Yao, C., Zhi, D., Baccarelli, A. A., Bandinelli, S., Deary, I., Dehghan, A., Eriksson, J., Herder, C., Järvelin, M-R., Levy, D. & Arnett, D. K., 4 Apr 2018, In: JAMA Cardiology.

    Research output: Contribution to journalArticlepeer-review

  70. Cognitive ability does not predict objectively measured sedentary behaviour: Evidence from three older cohorts

    Čukić, I., Shaw, R., Marioni, R., Chastin, S., Der, G., Dontje, M., Gill, J. M. R., Starr, J., Skelton, D. A., Radakovic, R., Cox, S., Dall, P., Gale, C. & Deary, I., 30 Mar 2018, In: Psychology and Aging. 33, 2, p. 288-296

    Research output: Contribution to journalArticlepeer-review

  71. Altered DNA methylation associated with a translocation linked to major mental illness

    McCartney, D. L., Walker, R. M., Morris, S. W., Anderson, S. M., Duff, B. J., Marioni, R. E., Millar, J. K., McCarthy, S. E., Ryan, N. M., Lawrie, S. M., Watson, A. R., Blackwood, D. H. R., Thomson, P. A., McIntosh, A. M., McCombie, W. R., Porteous, D. J. & Evans, K. L., 19 Mar 2018, In: npj Schizophrenia. 4, 1, p. 5

    Research output: Contribution to journalArticlepeer-review

  72. Phenotypic and genetic analysis of cognitive performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study

    Meijsen, J. J., Campbell, A., Hayward, C., Porteous, D. J., Deary, I. J., Marioni, R. E. & Nicodemus, K. K., 13 Mar 2018, In: Translational Psychiatry. 8, 1, p. 63

    Research output: Contribution to journalArticlepeer-review

  73. Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits

    Wu, Y., Zeng, J., Zhang, F., Zhu, Z., Qi, T., Zheng, Z., Luke R, L-J., Marioni, R., Martin, N. G., Montgomery, G. W., Deary, I. J., Visscher, P., Mcrae, A. F. & Yang, J., 2 Mar 2018, In: Nature Communications. 9, p. 1-14 14 p., 918.

    Research output: Contribution to journalArticlepeer-review

  74. Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism

    Luciano, M., Hagenaars, S. P., Davies, G., Hill, W. D., Clarke, T-K., Shirali, M., Harris, S. E., Marioni, R. E., Liewald, D. C., Fawns-Ritchie, C., Adams, M. J., Howard, D. M., Lewis, C. M., Gale, C. R., McIntosh, A. M. & Deary, I., 31 Jan 2018, In: Nature Genetics. 50, p. 6-11 6 p.

    Research output: Contribution to journalArticlepeer-review

  75. GWAS of epigenetic aging rates in blood reveals a critical role for TERT

    Lu, A. T., Xue, L., Salfati, E. L., Chen, B. H., Ferrucci, L., Levy, D., Joehanes, R., Murabito, J. M., Kiel, D. P., Tsai, P-C., Yet, I., Bell, J. T., Mangino, M., Tanaka, T., Mcrae, A. F., Marioni, R. E., Visscher, P. M., Wray, N. R., Deary, I. J., Levine, M. E. & 19 others, Quach, A., Assimes, T. L., Tsao, P. S., Absher, D., Stewart, J. D., Li, Y., Reiner, A. P., Hou, L., Baccarelli, A. A., Whitsel, E. A., Aviv, A., Cardona, A., Day, F. R., Wareham, N. J., Perry, J. R. B., Ong, K. K., Raj, K., Lunetta, K. L. & Horvath, S., 26 Jan 2018, In: Nature Communications. 9, 1, 387.

    Research output: Contribution to journalArticlepeer-review

  76. Meta-analysis of epigenome-wide association studies of cognitive abilities

    Marioni, R., Mcrae, A. F., Bressler, J., Colicino, E., Hannon, E., Li, S., prada, D., Smith, J. A., Trevisi, L., Tsai, P-C., Vojinovic, D., Simino, J., Levy, D., Liu, C., Mendelson, M. M., Satizabal, C. L., Yang, Q., Jhun, M. A., Kardia, S. L. R., Zhao, W. & 27 others, Bandinelli, S., Ferrucci, L., Hernandez, D., Singleton, A. B., Harris, S., Starr, J., Kiel, D. P., McLean, R. R., Just, A. C., Schwartz, J., Spiro, A., Vokonas, P., Amin, N., Ikram, M. A., Uitterlinden, A. G., van Meurs, J. B. J., Spector, T. D., Steves, C., Baccarelli, A. A., Bell, J. T., van Duijn, C. M., Fornage, M., Hsu, Y-H., Mill, J., Mosley, T. H., Seshadri, S. & Deary, I., 8 Jan 2018, In: Nature.

    Research output: Contribution to journalArticlepeer-review

  77. The epigenetic clock and objectively measured sedentary and walking behaviour in older adults: The Lothian Birth Cohort 1936

    Gale, C., Marioni, R., Čukić, I., Chastin, S., Dall, P., Dontje, M., Skelton, D. A. & Deary, I., 8 Jan 2018, In: Clinical Epigenetics. 10, 4, 4.

    Research output: Contribution to journalArticlepeer-review

  78. 2017
  79. Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

    Harris, S. E., Riggio, V., Evenden, L., Gilchrist, T., Mccafferty, S., Murphy, L., Wrobel, N., Taylor, A. M., Corley, J., Pattie, A., Cox, S. R., Martin-ruiz, C., Prendergast, J., Starr, J. M., Marioni, R. E. & Deary, I. J., 1 Dec 2017, In: Aging. 9, 12, p. 2489-2503 15 p.

    Research output: Contribution to journalArticlepeer-review

  80. DNA methylation analysis identifies loci for blood pressure regulation

    Richard, M. A., Huan, T., Ligthart, S., Gondalia, R., Jhun, M. A., Brody, J. A., Irvin, M. R., Marioni, R., Shen, J., Tsai, P-C., Montasser, M. E., Jia, Y., Syme, C., Salfati, E. L., Boerwinkle, E., Guan, W., Mosley, T. H., Bressler, J., Morrison, A. C., Liu, C. & 31 others, Mendelson, M. M., Uitterlinden, A. G., van Meurs, J. B., Franco, O. H., Zhang, G., Li, Y., Stewart, J. D., Bis, J. C., Psaty, B. M., Chen, Y-D. I., Kardia, S. L. R., Zhao, W., Turner, S. T., Absher, D., Aslibekyan, S., Starr, J. M., McRae, A. F., Hou, L., Just, A. C., Schwartz, J. D., Vokonas, P. S., Menni, C., Spector, T. D., Shuldiner, A., Damcott, C. M., Rotter, J. I., Palmas, W., Liu, Y., Smith, J. A., Deary, I. J. & BIOS Consortium, 30 Nov 2017, In: American Journal of Human Genetics. 101, 6, p. 888-902

    Research output: Contribution to journalArticlepeer-review

  81. Correction to: The epigenetic clock and telomere length are independently associated with chronological age and mortality

    Marioni, R. E., Harris, S. E., Shah, S., Mcrae, A. F., Von Zglinicki, T., Martin-ruiz, C., Wray, N. R., Visscher, P. M. & Deary, I. J., 27 Nov 2017, In: International Journal of Epidemiology.

    Research output: Contribution to journalArticlepeer-review

  82. Phenotypic and Genetic Analysis of Cognitive Performance in Major Depressive Disorder in the Generation Scotland: Scottish Family Health Study

    Meijsen, J. J., Campbell, A., Hayward, C., Porteous, D. J., Deary, I. J., Marioni, R. E. & Nicodemus, K. K., Nov 2017, In: Genetic Epidemiology. 41, 7, p. 684-684 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  83. An epigenome-wide association study meta-analysis of educational attainment

    Karlsson Linnér, R., Marioni, R. E., Rietveld, C. A., Simpkin, A. J., Davis, M., Armstrong, N. J., Auro, K., Baumbach, C., Bonder, M. J., Buchwald, J., Fiorito, G., Ismail, K., Iurato, S., Joensuu, A., Karell, P., Kasela, S., Lahti, J., Mcrae, A. F., Mandaviya, P. R., Seppälä, I. & 50 others, Wang, Y., Baglietto, L., Binder, E. B., Harris, S., Hodge, M., Horvath, S., Hurme, M., Johannesson, M., Latvala, A., Mather, K. A., Medland, S. E., Metspalu, A., Milani, L., Milne, R. L., Pattie, A., Pedersen, N. L., Peters, A., Polidoro, S., Räikkönen, K., Severi, G., Starr, J. M., Stolk, L., Waldenberger, M., Eriksson, J. G., Esko, T., Franke, L., Gieger, C., Giles, G. G., Hägg, S., Jousilahti, P., Kaprio, J., Kähönen, M., Lehtimäki, T., Martin, N. G., Van Meurs, J. B. C., Ollikainen, M., Perola, M., Posthuma, D., Raitakari, O. T., Sachdev, P. S., Taskesen, E., Uitterlinden, A. G., Vineis, P., Wijmenga, C., Wright, M. J., Relton, C., Davey Smith, G., Deary, I. J., Koellinger, P. D. & Benjamin, D. J., 31 Oct 2017, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  84. Genetically defined elevated homocysteine levels do not result in widespread changes of DNA methylation in leukocytes

    Mandaviya, P. R., Joehanes, R., Aïssi, D., Kühnel, B., Marioni, R. E., Truong, V., Stolk, L., Beekman, M., Bonder, M. J., Franke, L., Gieger, C., Huan, T., Ikram, M. A., Kunze, S., Liang, L., Lindemans, J., Liu, C., McRae, A. F., Mendelson, M. M., Müller-Nurasyid, M. & 19 others, Peters, A., Slagboom, P. E., Starr, J. M., Trégouët, D-A., Uitterlinden, A. G., van Greevenbroek, M. M. J., van Heemst, D., van Iterson, M., Wells, P. S., Yao, C., Deary, I. J., Gagnon, F., Heijmans, B. T., Levy, D., Morange, P-E., Waldenberger, M., Heil, S. G., van Meurs, J. B. J. & CHARGE Consortium Epigenetics group and BIOS Consortium, 30 Oct 2017, In: PLoS ONE. 12, 10, p. 1-19 e0182472.

    Research output: Contribution to journalArticlepeer-review

  85. New blood pressure–associated loci Identified in meta-analyses of 475 000 individuals

    Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-jensen, J., Brandslund, I., Farmaki, A., Fava, C., Ferreira, T., Herzig, K., Giri, A. & 121 others, Giulianini, F., Grove, M. L., Guo, X., Harris, S. E., Have, C. T., Havulinna, A. S., Zhang, H., Jørgensen, M. E., Käräjämäki, A., Kooperberg, C., Linneberg, A., Little, L., Liu, Y., Bonnycastle, L. L., Lu, Y., Mägi, R., Mahajan, A., Malerba, G., Marioni, R. E., Mei, H., Menni, C., Morrison, A. C., Padmanabhan, S., Palmas, W., Poveda, A., Rauramaa, R., Rayner, N. W., Riaz, M., Richard, M. A., Smith, J. A., Southam, L., Stančáková, A., Stirrups, K. E., Tragante, V., Tuomi, T., Tzoulaki, I., Varga, T. V., Weiss, S., Yiorkas, A. M., Young, R., Zhang, W., Barnes, M. R., Cabrera, C. P., Gao, H., Boehnke, M., Boerwinkle, E., Chambers, J. C., Connell, J. M., Christensen, C. K., De Boer, R. A., Deary, I. J., Dedoussis, G., Deloukas, P., Dominiczak, A. F., Dörr, M., Joehanes, R., Edwards, T. L., Esko, T., Fornage, M., Franceschini, N., Franks, P. W., Gambaro, G., Groop, L., Hallmans, G., Hansen, T., Hayward, C., Heikki, O., Ingelsson, E., Tuomilehto, J., Jarvelin, M., Kardia, S. L. R., Karpe, F., Kooner, J. S., Lakka, T. A., Langenberg, C., Lind, L., Loos, R. J. F., Laakso, M., Mccarthy, M. I., Melander, O., Mohlke, K. L., Morris, A. P., Palmer, C. N. A., Pedersen, O., Polasek, O., Poulter, N. R., Province, M. A., Psaty, B. M., Ridker, P. M., Rotter, J. I., Rudan, I., Salomaa, V., Samani, N. J., Sever, P. J., Skaaby, T., Stafford, J. M., Starr, J. M., Van Der Harst, P., Van Der Meer, P., Van Duijn, C. M., Vergnaud, A., Gudnason, V., Wareham, N. J., Wilson, J. G., Willer, C. J., Witte, D. R., Zeggini, E., Saleheen, D., Butterworth, A. S., Danesh, J., Asselbergs, F. W., Wain, L. V., Ehret, G. B., Chasman, D. I., Caulfield, M. J., Elliott, P., Lindgren, C. M., Levy, D., Newton-cheh, C., Munroe, P. B. & Howson, J. M. M., 13 Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5, p. e001778

    Research output: Contribution to journalArticlepeer-review

  86. Identification, replication and characterization of epigenetic remodelling in the aging genome: A cross population analysis

    Li, S., Christiansen, L., Christensen, K., Kruse, T. A., Redmond, P., Marioni, R., Deary, I. & Tan, Q., 15 Aug 2017, In: Scientific Reports. 7, p. 1-8 8183.

    Research output: Contribution to journalArticlepeer-review

  87. Molecular genetic contributions to self-rated health

    Harris, S. E., Hagenaars, S. P., Davies, G., Hill, W. D., Liewald, D. CM., Ritchie, S. J., Marioni, R. E., Sudlow, C. LM., Wardlaw, J. M., McIntosh, A. M., Gale, C. R., Deary, I. J., METASTROKE consortium, International Consortium for Blood Pressure, CHARGE consortium Aging and Longevity Group & CHARGE consortium Cognitive Group, Jun 2017, In: International Journal of Epidemiology. 46, 3, p. 994-1009

    Research output: Contribution to journalArticlepeer-review

  88. Cognitive Performance in Major Depressive Disorder in Generation Scotland: The Scottish Family Health Study (GS:SFHS)

    Meijsen, J., Campbell, A., McIntosh, A., Porteous, D., Deary, I., Marioni, R. & Nicodemus, K., 15 May 2017, In: Biological Psychiatry. 81, 10, p. S217-S217 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  89. Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

    Hägg, S., Zhan, Y., Karlsson, R., Gerritsen, L., Ploner, A., Van Der Lee, S. J., Broer, L., Deelen, J., Marioni, R. E., Wong, A., Lundquist, A., Zhu, G., Hansell, N. K., Sillanpää, E., Fedko, I. O., Amin, N. A., Beekman, M., De Craen, A. J. M., Degerman, S., Harris, S. E. & 25 others, Kan, K., Martin-ruiz, C. M., Montgomery, G. W., Adolfsson, A. N., Reynolds, C. A., Samani, N. J., Suchiman, H. E. D., Viljanen, A., Von Zglinicki, T., Wright, M. J., Hottenga, J., Boomsma, D. I., Rantanen, T., Kaprio, J. A., Nyholt, D. R., Martin, N. G., Nyberg, L., Adolfsson, R., Kuh, D., Starr, J. M., Deary, I. J., Slagboom, P. E., Van Duijn, C. M., Codd, V. & Pedersen, N. L., 18 Apr 2017, In: Translational Psychiatry. 7, 4, p. e1100

    Research output: Contribution to journalArticlepeer-review

  90. Genetic stratification to identify risk groups for Alzheimer's disease

    Marioni, R., Campbell, A., Hagenaars, S., Nagy, R., Amador, C., Hayward, C., Porteous, D., Visscher, P. M. & Deary, I., 4 Mar 2017, In: Journal of Alzheimer's Disease. 57, 1, p. 275-283 8 p.

    Research output: Contribution to journalArticlepeer-review

  91. Genetic prediction of male pattern baldness

    Hagenaars, S. P., Hill, W. D., Harris, S. E., Ritchie, S. J., Davies, G., Liewald, D. C., Gale, C. R., Porteous, D. J., Deary, I. J. & Marioni, R. E., 14 Feb 2017, In: PLoS Genetics. 13, 2, e1006594.

    Research output: Contribution to journalArticlepeer-review

  92. Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

    de Vries, P. S., Sabater-Lleal, M., Chasman, D. I., Trompet, S., Ahluwalia, T. S., Teumer, A., Kleber, M. E., Chen, M-H., Wang, J. J., Attia, J. R., Marioni, R. E., Steri, M., Weng, L-C., Pool, R., Grossmann, V., Brody, J. A., Venturini, C., Tanaka, T., Rose, L. M., Oldmeadow, C. & 66 others, Mazur, J., Basu, S., Frånberg, M., Yang, Q., Ligthart, S., Hottenga, J. J., Rumley, A., Mulas, A., de Craen, A. J. M., Grotevendt, A., Taylor, K. D., Delgado, G. E., Kifley, A., Lopez, L. M., Berentzen, T. L., Mangino, M., Bandinelli, S., Morrison, A. C., Hamsten, A., Tofler, G., de Maat, M. P. M., Draisma, H. H. M., Lowe, G. D., Zoledziewska, M., Sattar, N., Lackner, K. J., Völker, U., McKnight, B., Huang, J., Holliday, E. G., McEvoy, M. A., Starr, J. M., Hysi, P. G., Hernandez, D. G., Guan, W., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Psaty, B. M., Uitterlinden, A. G., de Geus, E. J. C., Stott, D. J., Binder, H., Hofman, A., Franco, O. H., Rotter, J. I., Ferrucci, L., Spector, T. D., Deary, I. J., März, W., Greinacher, A., Wild, P. S., Cucca, F., Boomsma, D. I., Watkins, H., Tang, W., Ridker, P. M., Jukema, J. W., Scott, R. J., Mitchell, P., Hansen, T., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 20 Jan 2017, In: PLoS ONE. 12, 1, p. e0167742

    Research output: Contribution to journalArticlepeer-review

  93. Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: A Mendelian randomization approach

    Mendelson, M. M., Marioni, R. E., Joehanes, R., Liu, C., Hedman, Å. K., Aslibekyan, S., Demerath, E. W., Guan, W., Zhi, D., Yao, C., Huan, T., Willinger, C., Chen, B. H., Courchesne, P., Multhaup, M. L., Irvin, M. R., Cohain, A., Schadt, E. E., Grove, M. L., Bressler, J. & 29 others, North, K. E., Sundstrom, J., Gustafsson, S., Shah, S., Mcrae, A. F., Harris, S. E., Gibson, J., Redmond, P., Corley, J., Murphy, L., Starr, J. M., Kleinbrink, E., Lipovich, L., Visscher, P. M., Wray, N. R., Krauss, R. M., Fallin, D., Feinberg, A. P., Absher, D. M., Fornage, M., Pankow, J. S., Lind, L., Fox, C. S., Ingelsson, E., Arnett, D. K., Boerwinkle, E., Liang, L., Levy, D. & Deary, I. J., 17 Jan 2017, In: PLoS Medicine. 14, 1, 30 p., e1002215.

    Research output: Contribution to journalArticlepeer-review

  94. Epigenetic patterns in blood associated with lipid traits predict incident coronary heart disease events and are enriched for results from genome-wide association studies

    Hedman, A. K., Mendelson, M. M., Marioni, R., Gustafsson, S., Joehanes, R., Irvin, M. R., Zhi, D., Sandling, J. K., Yao, C., Liu, C., Liang, L., Huan, T., Mcrae, A. F., Demissie, S., Shah, S., Starr, J., Adrienne Cupples, L., Deloukas, P., Spector, T. D., Sundström, J. & 6 others, Krauss, R. M., Arnett, D. K., Deary, I., Lind, L., Levy, D. & Ingelsson, E., 2017, In: Circulation: Cardiovascular Genetics. 10, 1, e001487.

    Research output: Contribution to journalArticlepeer-review

  95. 2016
  96. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

    Ligthart, S., Marzi, C., Aslibekyan, S., Mendelson, M. M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., Joehanes, R., Guan, W., Brody, J. A., Elks, C., Marioni, R., Jhun, M. A., Agha, G., Bressler, J., Ward-Caviness, C. K., Chen, B. H., Huan, T., Bakulski, K. & 67 others, Salfati, E. L., Fiorito, G., Wahl, S., Schramm, K., Sha, J., Hernandez, D. G., Just, A. C., Smith, J. A., Sotoodehnia, N., Pilling, L. C., Pankow, J. S., Tsao, P. S., Liu, C., Zhao, W., Guarrera, S., Michopoulos, V. J., Smith, A. K., Peters, M. J., Melzer, D., Vokonas, P., Fornage, M., Prokisch, H., Bis, J. C., Chu, A. Y., Herder, C., Grallert, H., Yao, C., Shah, S., McRae, A. F., Lin, H., Horvath, S., Fallin, D., Hofman, A., Wareham, N. J., Wiggins, K. L., Feinberg, A. P., Starr, J. M., Visscher, P. M., Murabito, J. M., Kardia, S. L. R., Absher, D. M., Binder, E. B., Singleton, A. B., Bandinelli, S., Peters, A., Waldenberger, M., Matullo, G., Schwartz, J. D., Demerath, E. W., Uitterlinden, A. G., van Meurs, J. B. J., Franco, O. H., Chen, Y-D. I., Levy, D., Turner, S. T., Deary, I. J., Ressler, K. J., Dupuis, J., Ferrucci, L., Ong, K. K., Assimes, T. L., Boerwinkle, E., Koenig, W., Arnett, D. K., Baccarelli, A. A., Benjamin, E. J. & Dehghan, A., 12 Dec 2016, In: Genome Biology. 17, 255, 15 p.

    Research output: Contribution to journalArticlepeer-review

  97. Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia

    Hagenaars, S. P., Harris, S. E., Davies, G., Hill, W. D., Liewald, D. C. M., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Cullen, B., Malik, R., METASTROKE Consortium, International Consortium for Blood Pressure GWAS, SpiroMeta Consortium, CHARGE Consortium Pulmonary Group, CHARGE consortium Aging and Longevity Group, Worrall, B. B., Sudlow, C. L. M., Wardlaw, J. M., Gallacher, J., Pell, J. & 4 others, McIntosh, A. M., Smith, D. J., Gale, C. R. & Deary, I. J., 30 Nov 2016, In: Molecular Psychiatry. 21, 11, p. 1624-1632 9 p.

    Research output: Contribution to journalArticlepeer-review

  98. Genetic variants linked to education predict longevity

    Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., Davies, G., Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D. C., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J., Gale, C. R. & 13 others, Deary, I. J., Social Science Genetic Association Consortium, Nagy, R., Amador, C., Läll, K., Metspalu, A., Liewald, D., Campbell, A., Wilson, J. F., Hayward, C., Esko, T., Porteous, D. J. & Gale, C. V., 22 Nov 2016, In: Proceedings of the National Academy of Sciences. 113, 47, p. 13366-13371 6 p.

    Research output: Contribution to journalArticlepeer-review

  99. Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank

    Hill, W. D., Hagenaars, S. P., Marioni, R. E., Harris, S. E., Liewald, D. C. M., Davies, G., Okbay, A., McIntosh, A. M., Gale, C. R. & Deary, I. J., 21 Nov 2016, In: Current Biology. 26, 22, p. 3083-3089 7 p.

    Research output: Contribution to journalArticlepeer-review

  100. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis

    Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S-J., Isaacs, A., Jhun, M. A., Kavousi, M., Li-Gao, R., Lyytikäinen, L-P., Marioni, R. E., Schminke, U., Stitziel, N. O., Tada, H., van Setten, J., Smith, A. V. & 31 others, Vojinovic, D., Yanek, L. R., Yao, J., Yerges-Armstrong, L. M., Amin, N., Baber, U., Borecki, I. B., Carr, J. J., Chen, Y-D. I., Cupples, L. A., de Jong, P. A., de Koning, H., de Vos, B. D., Demirkan, A., Fuster, V., Franco, O. H., Goodarzi, M. O., Harris, T. B., Heckbert, S. R., Heiss, G., Hoffmann, U., Hofman, A., Išgum, I., Jukema, J. W., Kähönen, M., Kardia, S. L. R., Kral, B. G., Wardlaw, J. M., Deary, I. J., Wilson, J. G. & CHARGE Consortium, 21 Nov 2016, In: Circulation: Cardiovascular Genetics.

    Research output: Contribution to journalArticlepeer-review

  101. A DNA methylation biomarker of alcohol consumption

    Liu, C., Marioni, R. E., Hedman, K. K., Pfeiffer, L., Tsai, P. C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., Elks, C. E., Aslibekyan, S., Brody, J. A., Kühnel, B., Herder, C., Almli, L. M., Zhi, D., Wang, Y., Huan, T., Yao, C. & 53 others, Mendelson, M. M., Joehanes, R., Liang, L., Love, S. A., Guan, W., Shah, S., McRae, A. F., Kretschmer, A., Prokisch, H., Strauch, K., Peters, A., Visscher, P. M., Wray, N. R., Guo, X., Wiggins, K. L., Smith, A. K., Binder, E. B., Ressler, K. J., Irvin, M. R., Absher, D. M., Hernandez, D., Ferrucci, L., Bandinelli, S., Lohman, K., Ding, J., Trevisi, L., Gustafsson, S., Sandling, J. H., Stolk, L., Uitterlinden, A. G., Yet, I., Castillo-Fernandez, J. E., Spector, T. D., Schwartz, J. D., Vokonas, P., Lind, L., Li, Y., Fornage, M., Arnett, D. K., Wareham, N. J., Sotoodehnia, N., Ong, K. K., van Meurs, J. B. J., Conneely, K. N., Baccarelli, A. A., Deary, I. J., Bell, J. T., North, K. E., Liu, Y., Waldenberger, M., London, S. J., Ingelsson, E. & Levy, D., 15 Nov 2016, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  102. Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

    Surendran, P., Drenos, F., Young, R., Warren, H., Cook, J. P., Manning, A. K., Grarup, N., Sim, X., Barnes, D. R., Witkowska, K., Staley, J. R., Tragante, V., Tukiainen, T., Yaghootkar, H., Masca, N., Freitag, D. F., Ferreira, T., Giannakopoulou, O., Tinker, A., Harakalova, M. & 31 others, Mihailov, E., Liu, C., Kraja, A. T., Nielsen, S. F., Rasheed, A., Samuel, M., Zhao, W., Bonnycastle, L. L., Jackson, A. U., Narisu, N., Swift, A. J., Southam, L., Marten, J., Huyghe, J. R., Stančáková, A., Fava, C., Ohlsson, T., Matchan, A., Stirrups, K. E., Bork-Jensen, J., Harris, S. E., Liewald, D. C. M., Marioni, R., Polasek, O., Rudan, I., Deary, I. J., Starr, J. M., Morris, A. D., Porteous, D. J., Hayward, C. & CHARGE-Heart Failure Consortium, Oct 2016, In: Nature Genetics.

    Research output: Contribution to journalArticlepeer-review

  103. DNA methylation-based measures of biological age: meta-analysis predicting time to death

    Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P-C., Roetker, N. S., Just, A. C., Demerath, E. W., Guan, W., Bressler, J., Fornage, M., Studenski, S., Vandiver, A. R., Moore, A. Z., Tanaka, T., Kiel, D. P., Liang, L., Vokonas, P., Schwartz, J. & 46 others, Lunetta, K. L., Murabito, J. M., Bandinelli, S., Hernandez, D. G., Melzer, D., Nalls, M., Pilling, L. C., Price, T. R., Singleton, A. B., Gieger, C., Holle, R., Kretschmer, A., Kronenberg, F., Kunze, S., Linseisen, J., Meisinger, C., Rathmann, W., Waldenberger, M., Visscher, P. M., Shah, S., Wray, N. R., McRae, A. F., Franco, O. H., Hofman, A., Uitterlinden, A. G., Absher, D., Assimes, T., Levine, M. E., Lu, A. T., Tsao, P. S., Hou, L., Manson, J. E., Carty, C. L., LaCroix, A. Z., Reiner, A. P., Spector, T. D., Feinberg, A. P., Levy, D., Baccarelli, A., van Meurs, J., Bell, J. T., Peters, A., Deary, I. J., Pankow, J. S., Ferrucci, L. & Horvath, S., 28 Sep 2016, In: Aging.

    Research output: Contribution to journalArticlepeer-review

  104. Epigenetic signatures of cigarette smoking

    Deary, I., Joehanes, R., Just, A. C. & Marioni, R., 20 Sep 2016, In: Circulation: Cardiovascular Genetics. 9, 5

    Research output: Contribution to journalArticlepeer-review

  105. Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits

    Pankratz, N., Schick, U. M., Zhou, Y., Zhou, W., Ahluwalia, T. S., Allende, M. L., Auer, P. L., Bork-Jensen, J., Brody, J. A., Chen, M. H., Clavo, V., Eicher, J. D., Grarup, N., Hagedorn, E. J., Hu, B., Hunker, K., Johnson, A. D., Leusink, M., Lu, Y., Lyytikainen, L. P. & 61 others, Manichaikul, A., Marioni, R., Nalls, M. A., Pazoki, R., Smith, A. V., Van Rooij, F. J. A., Yang, M. L., Zhang, X., Zhang, Y., Asselbergs, F. W., Boerwinkle, E., Borecki, I. B., Bottinger, E. P., Cushman, M., De Bakker, P. I. W., Deary, I., Dong, L., Feitosa, M. F., Floyd, J. S., Franceschini, N., Franco, O. H., Garcia, M. E., Grove, M. L., Gudnason, V., Hansen, T., Harris, T. B., Hofman, A., Jackson, R. D., Jia, J., Kahonen, M., Launer, L. J., Lehtimaki, T., Liewald, D., Linneberg, A., Liu, Y., Loos, R. J. F., Nguyen, V. M., Numans, M. E., Pedersen, O., Psaty, B. M., Raitakari, O. T., Rich, S. S., Rivadeneira, F., Di Sant, A. M. R., Rotter, J. I., Starr, J., Taylor, K. D., Thuesen, B. H., Tracy, R. P., Uitterlinden, A. G., Wang, J., Wang, J., Dehghan, A., Huo, Y., Adrienne Cupples, L., Wilson, J. G., Proia, R. L., Zon, L. I., O'Donnell, C. J., Reiner, A. P. & Ganesh, S. K., 1 Aug 2016, In: Nature Genetics. 48, 8, p. 867-876 10 p.

    Research output: Contribution to journalArticlepeer-review

  106. Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

    Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., Couvy-Duchesne, B. & 12 others, Graham, N., Mackay, D., Evans, J., Smith, B. H., Porteous, D. J., Medland, S. E., Martin, N. G., Holmans, P., McIntosh, A. M., Pell, J. P., Deary, I. J. & O'Donovan, M. C., 30 Jun 2016, In: Molecular Psychiatry. 21, 6, p. 749-757 9 p.

    Research output: Contribution to journalArticlepeer-review

  107. Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

    Davies, G., Marioni, R. E., Liewald, D. C., Hill, W. D., Hagenaars, S. P., Harris, S. E., Ritchie, S. J., Luciano, M., Fawns-Ritchie, C., Lyall, D., Cullen, B., Cox, S. R., Hayward, C., Porteous, D. J., Evans, J., Mcintosh, A. M., Gallacher, J., Craddock, N., Pell, J. P., Smith, D. J. & 2 others, Gale, C. R. & Deary, I. J., 30 Jun 2016, In: Molecular Psychiatry. 21, 6, p. 758-767 10 p.

    Research output: Contribution to journalArticlepeer-review

  108. Genome-wide association study identifies 74 loci associated with educational attainment

    LifeLines Cohort Study, 26 May 2016, In: Nature. 533, 7604, p. 539-542 4 p.

    Research output: Contribution to journalArticlepeer-review

  109. The epigenetic clock and telomere length are independently associated with chronological age and mortality

    Marioni, R., Harris, S., Deary, I., Visscher, P. M., Wray, N. R., Mcrae, A. F., Von Zglinicki, T., Shah, S. & Martin-ruiz, C., 13 Apr 2016, In: International Journal of Epidemiology.

    Research output: Contribution to journalArticlepeer-review

  110. Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

    Harris, S. E., Marioni, R. E., Martin-Ruiz, C., Pattie, A., Gow, A. J., Cox, S. R., Corley, J., von Zglinicki, T., Starr, J. M. & Deary, I. J., Mar 2016, In: Mechanisms of Ageing and Development. 154, p. 43-48 6 p.

    Research output: Contribution to journalArticlepeer-review

  111. DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy

    Lin, Q., Weidner, C. I., Costa, I. G., Marioni, R. E., Ferreira, M. R. P., Deary, I. J. & Wagner, W., 25 Feb 2016, In: Aging. 8, 2, p. 394-401 8 p.

    Research output: Contribution to journalArticlepeer-review

  112. Polygenic risk of ischemic stroke is associated with cognitive ability

    Harris, S. E., Malik, R., Marioni, R., Campbell, A., Seshadri, S., Worrall, B. B., Sudlow, C. L. M., Hayward, C., Bastin, M. E., Starr, J. M., Porteous, D. J., Wardlaw, J. M., Deary, I. J. & METASTROKE Consortium, 16 Feb 2016, In: Neurology. 86, 7, p. 611-618 8 p.

    Research output: Contribution to journalArticlepeer-review

  113. Assessing the genetic overlap between BMI and cognitive function

    Marioni, R. E., Yang, J., Dykiert, D., Mõttus, R., Campbell, A., Davies, G., Hayward, C., Porteous, D. J., Visscher, P. M., Deary, I. J. & CHARGE Cognitive Working Group, 9 Feb 2016, In: Molecular Psychiatry. 21, 10, p. 1477-1482

    Research output: Contribution to journalArticlepeer-review

  114. 2015
  115. A meta-analysis of 120,246 individuals identifies 18 new loci for fibrinogen concentration

    de Vries, P. S., Chasman, D. I., Sabater-Lleal, M., Chen, M-H., Huffman, J. E., Steri, M., Tang, W., Teumer, A., Marioni, R. E., Grossmann, V., Hottenga, J. J., Trompet, S., Müller-Nurasyid, M., Zhao, J. H., Brody, J. A., Kleber, M. E., Guo, X., Wang, J. J., Auer, P. L., Attia, J. R. & 111 others, Yanek, L. R., Ahluwalia, T. S., Lahti, J., Venturini, C., Tanaka, T., Bielak, L. F., Joshi, P. K., Rocanin-Arjo, A., Kolcic, I., Navarro, P., Rose, L. M., Oldmeadow, C., Riess, H., Mazur, J., Basu, S., Goel, A., Yang, Q., Ghanbari, M., Willemsen, G., Rumley, A., Fiorillo, E., de Craen, A. J. M., Grotevendt, A., Scott, R., Taylor, K. D., Delgado, G. E., Yao, J., Kifley, A., Kooperberg, C., Qayyum, R., Lopez, L. M., Berentzen, T. L., Räikkönen, K., Mangino, M., Bandinelli, S., Peyser, P. A., Wild, S., Trégouët, D-A., Wright, A. F., Marten, J., Zemunik, T., Morrison, A. C., Sennblad, B., Tofler, G., de Maat, M. P. M., de Geus, E. J. C., Lowe, G. D., Zoledziewska, M., Sattar, N., Binder, H., Völker, U., Waldenberger, M., Khaw, K-T., McKnight, B., Huang, J., Jenny, N. S., Holliday, E. G., Qi, L., McEvoy, M. G., Becker, D. M., Starr, J. M., Sarin, A-P., Hysi, P. G., Hernandez, D. G., Jhun, M. A., Campbell, H., Hamsten, A., Rivadeneira, F., McArdle, W. L., Slagboom, P. E., Zeller, T., Koenig, W., Psaty, B. M., Haritunians, T., Liu, J., Palotie, A., Uitterlinden, A. G., Stott, D. J., Hofman, A., Franco, O. H., Polasek, O., Rudan, I., Morange, P-E., Wilson, J. F., Kardia, S. L. R., Ferrucci, L., Spector, T. D., Eriksson, J. G., Hansen, T., Deary, I. J., Becker, L. C., Scott, R. J., Mitchell, R., März, W., Wareham, N. J., Peters, A., Greinacher, A., Wild, P. S., Jukema, J. W., Boomsma, D. I., Hayward, C., Cucca, F., Tracy, R., Watkins, H., Reiner, A. P., Folsom, A. R., Ridker, P. M., O'Donnell, C. J., Smith, N. L., Strachan, D. P. & Dehghan, A., 10 Nov 2015, In: Human Molecular Genetics.

    Research output: Contribution to journalArticlepeer-review

  116. Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium

    Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjørngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. S., Wannamethee, S. G., Lahti, J., Räikkönen, K. & 40 others, Palotie, A., Wong, A., Dalgård, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K. O., Kuh, D., Eriksson, J. G., Whincup, P. H., Mbarek, H., de Geus, E. J. C., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D. A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J. W., Power, C., Hyppönen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimäki, M., Smith, B. H., Hayward, C., Sørensen, T. I. A., Thuesen, B. H., Sattar, N., Morris, R. W., Romundstad, P. R., Munafò, M. R., Jarvelin, M-R. & Husemoen, L. L. N., 4 Nov 2015, In: Circulation: Cardiovascular Genetics.

    Research output: Contribution to journalArticlepeer-review

  117. Social activity, cognitive decline and dementia risk: a 20-year prospective cohort study

    Marioni, R. E., Proust-Lima, C., Amieva, H., Brayne, C., Matthews, F. E., Dartigues, J-F. & Jacqmin-Gadda, H., 24 Oct 2015, In: BMC Public Health. 15, 1, p. 1089

    Research output: Contribution to journalArticlepeer-review

  118. Differential effects of the APOE e4 allele on different domains of cognitive ability across the life-course

    Generation Scotland, Hayward, C., Porteous, D. & Deary, I., 23 Sep 2015, In: European Journal of Human Genetics.

    Research output: Contribution to journalArticlepeer-review

  119. Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

    Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 11 Aug 2015, In: BMJ Open. 5, 8, p. e008808

    Research output: Contribution to journalArticlepeer-review

  120. Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations

    Shah, S., Bonder, M. J., Marioni, R. E., Zhu, Z., McRae, A. F., Zhernakova, A., Harris, S. E., Liewald, D., Henders, A. K., Mendelson, M. M., Liu, C., Joehanes, R., Liang, L., Levy, D., Martin, N. G., Starr, J. M., Wijmenga, C., Wray, N. R., Yang, J., Montgomery, G. W. & 4 others, Franke, L., Deary, I. J., Visscher, P. M. & BIOS Consortium, 2 Jul 2015, In: American Journal of Human Genetics.

    Research output: Contribution to journalArticlepeer-review

  121. Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

    Huffman, J. E., de Vries, P., Morrison, A. C., Sabater-Lleal, M., Kacprowski, T., Auer, P. L., Brody, J. A., Chasman, D. I., Chen, M-H., Guo, X., Lin, L-A., Marioni, R., muller-nurasyid, M., Yanek, L. R., Pankratz, N., Grove, M. L., de Maat, M. P. M., Cushman, M., Wiggins, K. L., Qi, L. & 47 others, Sennblad, B., Harris, S., Polašek, O., Riess, H., Rivadeneira, F., Rose, L. M., Goel, A., Taylor, K. D., Teumer, A., Uitterlinden, A. G., Vaidya, D., Yao, J., Tang, W., Levy, D., Waldenberger, M., Becker, D. M., Folsom, A. R., Giulianini, F., Greinacher, A., Hofman, A., Huang, C-C., Kooperberg, C., Silveira, A., Starr, J. M., Strauch, K., Strawbridge, R. J., Wright, A. F., McKnight, B., Franco, O. H., Zakai, N., Mathias, R. A., Psaty, B. M., Ridker, P. M., Tofler, G. H., Voelker, U., Watkins, H., Fornage, M., Hamsten, A., Deary, I., Boerwinkle, E., Koenig, W., Rotter, J. I., Hayward, C., Dehghan, A., Reiner, A. P., O'Donnell, C. J. & Smith, N. L., 23 Jun 2015, In: Blood.

    Research output: Contribution to journalArticlepeer-review

  122. Current Versus Lifetime Depression, APOE Variation, and Their Interaction on Cognitive Performance in Younger and Older Adults

    Luciano, M., Pujals, A. M. F., Marioni, R. E., Campbell, A., Hayward, C., MacIntyre, D. J., Porteous, D. J., McIntosh, A. M., Deary, I. J. & Generation Scotland, 13 Jun 2015, In: Psychosomatic Medicine. 77, 5, p. 480-492 13 p.

    Research output: Contribution to journalArticlepeer-review

  123. Exome Sequencing to Detect Rare Variants Associated With General Cognitive Ability: A Pilot Study

    Generation Scotland, 25 Apr 2015, In: Twin Research and Human Genetics. 18, 2, p. 117-125 9 p.

    Research output: Contribution to journalArticlepeer-review

  124. Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

    Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V., Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., van der Lee, S. J., Le Hellard, S., Liu, T., Marioni, R. E., Oldmeadow, C., Postmus, I., Smith, A. V., Smith, J. A., Thalamuthu, A., Thomson, R. & 109 others, Vitart, V., Wang, J., Yu, L., Zgaga, L., Zhao, W., Boxall, R., Harris, S. E., Hill, W. D., Liewald, D. C., Luciano, M., Adams, H., Ames, D., Amin, N., Amouyel, P., Assareh, A. A., Au, R., Becker, J. T., Beiser, A., Berr, C., Bertram, L., Boerwinkle, E., Buckley, B. M., Campbell, H., Corley, J., De Jager, P. L., Dufouil, C., Eriksson, J. G., Espeseth, T., Faul, J. D., Ford, I., Generation Scotland, Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Heiss, G., Hofman, A., Holliday, E. G., Huffman, J., Kardia, S. L. R., Kochan, N., Knopman, D. S., Kwok, J. B., Lambert, J-C., Lee, T., Li, G., Li, S-C., Loitfelder, M., Lopez, O. L., Lundervold, A. J., Lundqvist, A., Mather, K. A., Mirza, S. S., Nyberg, L., Oostra, B. A., Palotie, A., Papenberg, G., Pattie, A., Petrovic, K., Polasek, O., Psaty, B. M., Redmond, P., Reppermund, S., Rotter, J. I., Schmidt, H., Schuur, M., Schofield, P. W., Scott, R. J., Steen, V. M., Stott, D. J., van Swieten, J. C., Taylor, K. D., Trollor, J., Trompet, S., Uitterlinden, A. G., Weinstein, G., Widen, E., Windham, B. G., Jukema, J. W., Wright, A. F., Wright, M. J., Yang, Q., Amieva, H., Attia, J. R., Bennett, D. A., Brodaty, H., de Craen, A. J. M., Hayward, C., Ikram, M. A., Lindenberger, U., Nilsson, L-S., Porteous, D. J., Räikkönen, K., Reinvang, I., Rudan, I., Sachdev, P. S., Schmidt, R., Schofield, P. R., Srikanth, V., Starr, J. M., Turner, S. T., Weir, D. R., Wilson, J. F., Duijn, C. V., Launer, L., Fitzpatrick, A. L., Seshadri, S., Mosley Jr, T. H. & Deary, I. J., 28 Feb 2015, In: Molecular Psychiatry. 20, 2, p. 183-192 10 p.

    Research output: Contribution to journalArticlepeer-review

  125. DNA methylation age of blood predicts all-cause mortality in later life

    Marioni, R. E., Shah, S., McRae, A. F., Chen, B. H., Colicino, E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Feinberg, A. P., Fallin, M. D., Multhaup, M. L., Jaffe, A. E., Joehanes, R. & 11 others, Schwartz, J., Just, A. C., Lunetta, K. L., Murabito, J. M., Starr, J. M., Horvath, S., Baccarelli, A. A., Levy, D., Visscher, P. M., Wray, N. R. & Deary, I. J., 30 Jan 2015, In: Genome Biology. 16, 12 p., 25.

    Research output: Contribution to journalArticlepeer-review

  126. Markers of psychological differences and social and health inequalities: possible genetic and phenotypic overlaps

    Mõttus, R., Marioni, R. & Deary, I., 2015, In: Journal of Personality.

    Research output: Contribution to journalArticlepeer-review

  127. Structural brain MRI trait polygenic score prediction of cognitive abilities

    Generation Scotland & SINAPSE Collaborative Grp, 2015, In: Twin Research and Human Genetics. 18, p. 738-745 8 p.

    Research output: Contribution to journalArticlepeer-review

  128. The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

    Marioni, R. E., Shah, S., McRae, A. F., Ritchie, S. J., Muniz-Terrera, G., Harris, S. E., Gibson, J., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Taylor, A., Murphy, L., Starr, J. M., Horvath, S., Visscher, P. M., Wray, N. R. & Deary, I. J., 2015, In: International Journal of Epidemiology. 44, 4, p. 1388-1396

    Research output: Contribution to journalArticlepeer-review

  129. 2014
  130. Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

    Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Asvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. S., Treur, J. L., Willemsen, G. & 44 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., Kisialiou, A., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Frayling, T., Nohr, E. A., Christiansen, L., Ohm Kyvik, K., Kuh, D., Watt, G., Eriksson, J., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 4 Dec 2014, In: PLoS Genetics. 10, 12, e1004799.

    Research output: Contribution to journalArticlepeer-review

  131. Genetic and environmental exposures constrain epigenetic drift over the human life course

    Shah, S., Mcrae, A. F., Marioni, R. E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Starr, J. M., Wray, N. R., Deary, I. & Visscher, P. M., 1 Nov 2014, In: Genome Research. 24, 11, p. 1725-1733

    Research output: Contribution to journalArticlepeer-review

  132. Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

    Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Gabrielsen, M. E., Skorpen, F., Marioni, R. E., Campbell, A., Engmann, J., Mirza, S. S., Loukola, A., Laatikainen, T., Partonen, T., Kaakinen, M., Ducci, F., Cavadino, A., Husemoen, L. L. N., Ahluwalia, T. S., Jacobsen, R. K., Skaaby, T., Ebstrup, J. F. & 42 others, Mortensen, E. L., Minica, C. C., Vink, J. M., Willemsen, G., Marques-Vidal, P., Dale, C. E., Amuzu, A., Lennon, L. T., Lahti, J., Palotie, A., Räikkönen, K., Wong, A., Paternoster, L., Wong, A. P-Y., Horwood, L. J., Murphy, M., Johnstone, E. C., Kennedy, M. A., Pausova, Z., Paus, T., Ben-Shlomo, Y., Nohr, E. A., Kuh, D., Kivimaki, M., Eriksson, J. G., Morris, R. W., Casas, J. P., Preisig, M., Boomsma, D. I., Linneberg, A., Power, C., Hyppönen, E., Veijola, J., Jarvelin, M-R., Korhonen, T., Tiemeier, H., Kumari, M., Porteous, D. J., Hayward, C., Romundstad, P. R., Smith, G. D. & Munafò, M. R., 7 Oct 2014, In: BMJ Open. 4, 10, p. e006141

    Research output: Contribution to journalArticlepeer-review

  133. Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

    Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., de Leeuw, C., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Smith, G. D., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 23 Sep 2014, In: Proceedings of the National Academy of Sciences. 111, 38, p. 13790-13794 5 p.

    Research output: Contribution to journalArticlepeer-review

  134. Molecular genetic contributions to socioeconomic status and intelligence

    Marioni, R. E., Davies, G., Hayward, C., Liewald, D., Kerr, S. M., Campbell, A., Luciano, M., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hastie, N. D., Wright, A. F., Porteous, D. J., Visscher, P. M. & Deary, I. J., 1 May 2014, In: Intelligence. 44, 100, p. 26-32

    Research output: Contribution to journalArticlepeer-review

  135. Improving access to psychological therapies and older people: Findings from the Eastern Region

    Matthew Prina, A., Marioni, R. E., Hammond, G. C., Jones, P. B., Brayne, C. & Dening, T., May 2014, In: Behaviour Research and Therapy. 56, p. 75-81 7 p.

    Research output: Contribution to journalArticlepeer-review

  136. The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability

    Marioni, R. E., Penke, L., Davies, G., Huffman, J. E., Hayward, C. & Deary, I. J., 22 Apr 2014, In: Proceedings of the Royal Society B-Biological Sciences. 281, 1781, 7 p., 20140117.

    Research output: Contribution to journalArticlepeer-review

  137. C-reactive protein, APOE genotype and longitudinal cognitive change in an older population

    Lima, T. A. S., Adler, A. L., Minett, T., Matthews, F. E., Brayne, C., Marioni, R. E. & on behalf of the Medical Research Council Cognitive Function and Ageing Study, Mar 2014, In: Age and Ageing. 43, 2

    Research output: Contribution to journalArticlepeer-review

  138. Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study

    Generation Scotland, Mar 2014, In: Behavior Genetics. 44, 2, p. 91-96 6 p.

    Research output: Contribution to journalArticlepeer-review

  139. Cognitive lifestyle jointly predicts longitudinal cognitive decline and mortality risk

    Marioni, R. E., Proust-Lima, C., Amieva, H., Brayne, C., Matthews, F. E., Dartigues, J-F. & Jacqmin-Gadda, H., 28 Feb 2014, In: European Journal of Epidemiology. 9 p.

    Research output: Contribution to journalArticlepeer-review

  140. Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

    Peloso, G. M., Auer, P. L., Bis, J. C., Voorman, A., Morrison, A. C., Stitziel, N. O., Brody, J. A., Khetarpal, S. A., Crosby, J. R., Fomage, M., Isaacs, A., Jakobsdottir, J., Feitosa, M. F., Davies, G., Huffman, J. E., Manichaikul, A., Davis, B., Lohman, K., Joon, A. Y., Smith, A. V. & 31 others, Grove, M. L., Zanoni, P., Redon, V., Demissie, S., Lawson, K., Peters, U., Carlson, C., Jackson, R. D., Ryckman, K. K., Mackey, R. H., Robinson, J. G., Siscovick, D. S., Schreiner, P. J., Mychaleckyj, J. C., Pankow, J. S., Holman, A., Uitterlinden, A. G., Harris, T. B., Taylor, K. D., Stafford, J. M., Reynolds, L. M., Marioni, R. E., Dehghan, A., Franco, O. H., Patele, A. P., Starr, J. M., Rudan, I., Hayward, C., Polasek, O., Deary, I. J. & NHLBI GO Exome Sequencing Project, 6 Feb 2014, In: American Journal of Human Genetics. 94, 2, p. 223-232 10 p.

    Research output: Contribution to journalArticlepeer-review

  141. Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

    Hill, W. D., Davies, G., Van De Lagemaat, L. N., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S., Espeseth, T. & 7 others, Lundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C. & Deary, I. J., 7 Jan 2014, In: Translational Psychiatry. 4, 1, 8 p., 341.

    Research output: Contribution to journalArticlepeer-review

  142. 2012
  143. Examining the influence of gender, education, social class and birth cohort on MMSE tracking over time: a population-based prospective cohort study

    Matthews, F., Marioni, R. & Brayne, C., 13 Aug 2012, In: BMC Geriatrics. 12, 1

    Research output: Contribution to journalArticlepeer-review

  144. Active Cognitive Lifestyle Associates with Cognitive Recovery and a Reduced Risk of Cognitive Decline

    Marioni, R. E., van den Hout, A., Valenzuela, M. J., Brayne, C., Matthews, F. E. & MRC Cognitive Function Ageing, 2012, In: Journal of Alzheimer's Disease. 28, 1, p. 223-230 8 p.

    Research output: Contribution to journalArticlepeer-review

  145. Active cognitive lifestyle is associated with positive cognitive health transitions and compression of morbidity from age sixty-five.

    Marioni, R., Valenzuela, M., Van Den Hout, A., Brayne, C. & Matthews, F., 2012, In: PLoS ONE. 7, 12, e50940.

    Research output: Contribution to journalArticlepeer-review

  146. 2011
  147. The reliability of assigning individuals to cognitive states using the Mini Mental-State Examination: a population-based prospective cohort study

    Marioni, R. E., Chatfield, M., Brayne, C., Matthews, F. E. & Med Res Council, 6 Sep 2011, In: BMC Medical Research Methodology. 11, p. - 6 p., 127.

    Research output: Contribution to journalArticlepeer-review

  148. Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts

    Marioni, R., Deary, I. J., Murray, G. D., Lowe, G. D. O., Strachan, M. W. J., Luciano, M., Houlihan, L., Gow, A. J., Harris, S. E., Rumley, A., Stewart, M. C., Fowkes, F. G. R. & Price, J. F., 1 Sep 2011, In: Behavior Genetics. 41, 5, p. 691-699 9 p.

    Research output: Contribution to journalArticlepeer-review

  149. Chronic Kidney Disease: A Risk Factor for Dementia Onset: A Population-Based Study. The Osaki-Tajiri Project

    Sasaki, Y., Marioni, R. E., Kasai, M., Ishii, H., Yamaguchi, S. & Meguro, K., Jul 2011, In: Journal of the American Geriatrics Society. 59, 7, p. 1175-1181 7 p.

    Research output: Contribution to journalArticlepeer-review

  150. The association between late-life cognitive test scores and retrospective informant interview data

    Marioni, R. E., Matthews, F. E., Brayne, C. & MRC Cognitive Function & Ageing St, Mar 2011, In: International Psychogeriatrics. 23, 2, p. 274-279 6 p.

    Research output: Contribution to journalArticlepeer-review

  151. Cognitive function, dementia and type 2 diabetes mellitus in the elderly

    Strachan, M. W. J., Reynolds, R. M., Marioni, R. & Price, J. F., Feb 2011, In: Nature reviews endocrinology. 7, 2, p. 108-114 7 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  152. 2010
  153. Association Between Polymorphisms of the Dopamine Receptor D2 and Catechol-o-Methyl Transferase Genes and Cognitive Function

    Bolton, J. L., Marioni, R. E., Deary, I. J., Harris, S. E., Stewart, M. C., Murray, G. D., Fowkes, F. G. R. & Price, J. F., 1 Sep 2010, In: Behavior Genetics. 40, 5, p. 630-638

    Research output: Contribution to journalArticlepeer-review

  154. Variation in the uric acid transporter gene (SLC2A9) and memory performance

    Houlihan, L. M., Wyatt, N. D., Harris, S. E., Hayward, C., Gow, A. J., Marioni, R. E., Strachan, M. W. J., Price, J. F., Starr, J., Wright, A. F. & Deary, I. J., 1 Jun 2010, In: Human Molecular Genetics. 19, 11, p. 2321-2330 10 p.

    Research output: Contribution to journalArticlepeer-review

  155. Blood rheology and cognition in the Edinburgh Type 2 Diabetes Study

    Marioni, R. E., Deary, I. J., Strachan, M. W., Lowe, G. D., Rumley, A., Murray, G. D. & Price, J. F., 1 May 2010, In: Age and Ageing. 39, 3, p. 354-359

    Research output: Contribution to journalArticlepeer-review

  156. Associations between polymorphisms in five inflammation-related genes and cognitive ability in older persons

    Marioni, R. E., Deary, I., Murray, G. D., Fowkes, F. G. R. & Price, J. F., Apr 2010, In: Genes, Brain and Behavior. 9, 3, p. 348-352 5 p.

    Research output: Contribution to journalArticlepeer-review

  157. Association Between Raised Inflammatory Markers and Cognitive Decline in Elderly People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

    Marioni, R., Strachan, M. W. J., Reynolds, R. M., Lowe, G. D. O., Mitchell, R. J., Fowkes, F. G. R., Frier, B. M., Lee, A. J., Butcher, I., Rumley, A., Murray, G. D., Deary, I. J. & Price, J., Mar 2010, In: Diabetes. 59, 3, p. 710-713 4 p.

    Research output: Contribution to journalArticlepeer-review

  158. Genetic Variants Associated With Altered Plasma Levels of C-Reactive Protein are not Associated With Late-Life Cognitive Ability in Four Scottish Samples

    Marioni, R. E., Deary, I. J., Murray, G. D., Lowe, G. D. O., Rafnsson, S. B., Strachan, M. W. J., Luciano, M., Houlihan, L., Gow, A. J., Harris, S. E., Stewart, M. C., Rumley, A., Fowkes, F. G. R. & Price, J. F., 1 Jan 2010, In: Behavior Genetics. 40, 1, p. 3-11

    Research output: Contribution to journalArticlepeer-review

  159. 2009
  160. Age-associated cognitive decline

    Deary, I. J., Corley, J., Gow, A. J., Harris, S., Houlihan, L., Marioni, R. E., Penke, L., Rafnsson, S. B. & Starr, J., 1 Dec 2009, In: British Medical Bulletin. 92, 1, p. 135-152

    Research output: Contribution to journalArticlepeer-review

  161. Peripheral Levels of Fibrinogen, C-Reactive Protein, and Plasma Viscosity Predict Future Cognitive Decline in Individuals Without Dementia

    Marioni, R. E., Stewart, M. C., Murray, G. D., Deary, I. J., Fowkes, F. G. R., Lowe, G. D. O., Rumley, A. & Price, J. F., 1 Oct 2009, In: Psychosomatic Medicine. 71, 8, p. 901-906

    Research output: Contribution to journalArticlepeer-review

  162. No association between cholinergic muscarinic receptor 2 (CHRM2) genetic variation and cognitive abilities in three independent samples

    Lind, P. A., Luciano, M., Horan, M. A., Marioni, R. E., Wright, M. J., Bates, T. C., Rabbitt, P., Harris, S. E., Davidson, Y., Deary, I. J., Gibbons, L., Pickles, A., Ollier, W., Pendleton, N., Price, J. F., Payton, A. & Martin, N. G., Sep 2009, In: Behavior Genetics. 39, 5, p. 513-523 11 p.

    Research output: Contribution to journalArticlepeer-review

  163. Reverse Causation in the Association Between C-Reactive Protein and Fibrinogen Levels and Cognitive Abilities in an Aging Sample

    Luciano, M., Marioni, R. E., Gow, A. J., Starr, J. & Deary, I. J., May 2009, In: Psychosomatic Medicine. 71, 4, p. 404-409

    Research output: Contribution to journalArticlepeer-review

  164. Inflammation and Cognition-A Causal Association?

    Marioni, R., Price, J., Deary, I., Murray, G. & Lowe, G., Apr 2009, In: Stroke. 40, 4, p. E131-E131 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  165. Association of KIBRA and memory

    Bates, T. C., Price, J., Harris, S., Marioni, R. E., Fowkes, F. G. R., Stewart, M., Murray, G. D., Whalley, L. J., Starr, J. & Deary, I. J., 2009, In: Neuroscience Letters. 458, 3, p. 140-143 4 p.

    Research output: Contribution to journalArticlepeer-review

  166. 2008
  167. Is non-dipping of nocturnal blood pressure in type 2 diabetes associated with increased incidence of microalbuminuria?

    Heggie, A. J., Adamson, K. A., Marioni, R. E., Padfield, P. L. & Strachan, M. W., 1 May 2008, In: British Journal of Diabetes and Vascular Disease. 8, 3, p. 136-139

    Research output: Contribution to journalArticlepeer-review

  168. Productivity cost model of the treatment of rheumatoid arthritis with abatacept

    Burton, W. N., Morrison, A., Yuan, Y., Li, T., Marioni, R. E. & Maclean, R., 1 Mar 2008, In: Journal of Medical Economics (JME). 11, 1, p. 3-21

    Research output: Contribution to journalArticlepeer-review

  169. 2007
  170. Serum angiotensin-converting enzyme and frequency of severe hypoglycaemia in Type 1 diabetes: does a relationship exist?

    Zammitt, N. N., Geddes, J., Warren, R. E., Marioni, R., Ashby, J. P. & Frier, B. M., Dec 2007, In: Diabetic Medicine. 24, 12, p. 1449-1454 6 p.

    Research output: Contribution to journalArticlepeer-review