(Former employee or visitor)
Willingness to take PhD students: Yes
2005 | Doctor of Science, University of Edinburgh Development and Plasticity of Neuromuscular Innervation |
1977 | Doctor of Philosophy (PhD), Newcastle University On the involvement of the neuromuscular junction in murine muscular dystrophy |
1974 | Bachelor of Science, Durham University |
Research expertise | Electrophysiology and confocal microscopy of nerve, muscle and neuromuscular synapses |
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Career
1974-77: MRC Student, Muscular Dystrophy Laboratories, Newcastle upon Tyne
1977-79: MDA Postdoctoral Fellow, University of Colorado School of Medicine, Denver, USA
1979-80: Wellcome Travelling European Fellow, University of Oslo, Norway
1980-2005: Lecturer then Senior Lecturer then Reader, University of Edinburgh
2007-2008: Research Leave Fellow, Royal Society of Edinburgh
2005-present: Professor of Cellular Neuroscience, University of Edinburgh
Other
1977-2016: Over 130 Research Publications; >3200 citations; hIndex=34; i10 index=56 (source Google Scholar)
2006-2009: Founder and first Acting Director, Edinburgh Motor Neurone Disease Research Group then Euan MacDonald Centre for MND Research
2015: Delsys Prize for Innovation in Electromyography
Degrees
1974: BSc (Joint Hons) Chemistry & Zoology, University of Durham
1977: PhD, University of Newcastle upon Tyne
2005: DSc, University of Edinburgh
Membership of Learned Societies
Physiological Society
British Neuroscience Association
Society for Neuroscience
I teach mainly in the area of my research experience/expertise: general neuroscience but focused on the physiology, developmental biology, plasticity and pathology of excitable cells, especially motor neurones and their neuromuscular synapses.
Undergraduate
Year 2: Biomedical Sciences 2
Year 3: Biomedical Sciences 3, Neuroscience 3
Year 4: Honours Neuroscience (Programme Manager, 2009-2013)
Honours Electives:
Neurotransmitters in Action (2014-present)
Neuromuscular Junctions in Health and Disease (2003-2013)
Postgraduate
MSc 1: MSc by Research Integrative Neuroscience (Programme Manager: 1994-2005)
My main research interest is in the biology of motor neurones and their connections in skeletal muscle, especially the development, plasticity, degeneration, regeneration and pathology of neuromuscular junctions. Synapses at neuromuscular junctions are the first components of a motor neurone to degenerate in many forms of Motor Neurone Disease (MND/ALS). We combine electrophysiological techniques and imaging to find out how this synaptic degeneration is triggered and to explore ways that it could be slowed down or completely prevented: using gene-based therapies, drugs or exercise. I also collaborate in research into mechanisms of organophosphorus toxicity at neuromuscular junctions, and in the development of microendoscopic imaging technologies intended for observation of living neuromuscular junctions that might ultimately be used to diagnose, monitor and treat the progression of MND and other neuromuscular diseases. I also have an emerging interest in the utility of the larval Drosophila (fruit-fly) neuromuscular system as a model for investigation of neuromuscular synaptic physiology and mechanisms of neurodegenerative disease.
http://www.nutshell-videos.ed.ac.uk/richard-ribchester-neuromuscular-junctions/
http://www.euanmacdonaldcentre.com/professor-richard-ribchester/
http://www.delsys.com/news/delsys-prize/winner-2015/
http://www.ccns.ed.ac.uk/People/Academic/ribchester.html
Internal Collaborations:
Professor Michael Eddleston
Professor Richard Clutton
Professor Thomas Gillingwater
Dr Paul Skehel
Dr Lyndsay Murray
External Collaboration
Professor David Beeson, Weatherall Institute of Molecular Medicine, University of Oxford
Professor Michael Coleman, John van Geest Centre for Brain Repair, University of Cambrige
Professsor Gregory Lnenicka, University at Albany, USA
Development, physiology and plasticity of neuromuscular innervation
1992 (Oct-Dec): Visiting Researcher, Department of Physiology, University of Colorado Health Sciences Center, Denver, USA
2007 (Oct-Dec): Visiting Researcher, MRC Mammalian Genetics unit, Harwell
2008 (Jan-Mar): Visiting Researcher, The Babraham Institute
2008 (Apr-Jul): Visiting Researcher, Children's Hospital and Department of Neurobiology, Harvard Medical School, USA
2012-2014: Visiting Researcher, Department of Biological Sciences, University at Albany, USA
9:30 am - 6:30 pm (email to 11:00 pm)
Primary Affiliation: Centre for Cognitive and Neural Systems
Secondary Affiliations:
Centre for Integrative Physiology
Centre for Neuroregeneration
Euan MacDonald Centre for Motor Neurone Diseaese Research
Live imaging of structure and function in motor neurones and their connections.
(http://www.edneurophd.ed.ac.uk/basic-neuroscience-informatics-neurones-and-networks/live-imaging-structure-and-function-motor)
Experimental and computational analysis of neuromuscular synaptic dysfunction in organophosphorus toxicity: a ‘population of models’ approach. (Pending)
PhD Students
Simon Parson (1988-91; Ph.D. awarded, 1991)
Graeme Bryce (1989-92; Ph.D. awarded, 1993)
Richard Mattison (1995-1998; PhD awarded, 1999)
Ellen M. Costanzo (1996-1999; PhD awarded 1999)
Thomas H. Gillingwater(1998-2001; PhD awarded 2001)
Amanda Carter-Kimpton (1998-2001; PhD awarded 2001)
Felipe A. Court (2001-2004; PhD awarded 2004)
Thomas M. Wishart (2002-2005; PhD awarded 2005)
Li Fan (2003-2007; PhD awarded 2007)
Oyinlola O.R. Oyebode (2005 – 2008; PhD awarded 2008)
Adrianna Teriakidis (2006-2009; PhD awarded 2010)
Rosalind Brown (2008-2011; PhD awarded 2012)
Kosala Dissanayake (2011-2014; PhD awarded 2015)
Research output: Contribution to journal › Comment/debate
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
ID: 13072