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Research Interests

I am currently investigating neuron-astrocyte signaling processes using bioinformatic network analysis in addition to broader machine learning and systems biology methods. Previous experimentation has produced cultures of neurons from stem cells, with recent studies demonstrating increased differentiation, maturation and synaptogenesis when co-cultured with astrocytes. Through use of co-culture data using neurons of one species and astrocytes of another (mouse, rat or human) I will separate, by species and thus by cell, and analyse RNA-Seq and epigenetic data to explore and identify signaling processes between the cell types with the hope of identifying the source of the beneficial developmental effects observed in co-culture.

ID: 18050692