Edinburgh Research Explorer

Prof Scott Webster

Personal Chair of Medicines Discovery

  1. 2019
  2. Vitamin A deficiency impairs contextual fear memory in rats: abnormalities in glucocorticoid pathway

    Bonhomme, D., Alfos, S., Webster, S. P., Wolff, M., Pallet, V. & Touyarot, K., 15 Oct 2019, In : Journal of Neuroendocrinology.

    Research output: Contribution to journalArticle

  3. Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury

    Zheng, X., Zhang, A., Binnie, M., McGuire, K., Webster, S., Hughes, J., Howie, S. E. M. & Mole, D., 13 Feb 2019, In : Experimental and Molecular Medicine. 51, 15.

    Research output: Contribution to journalArticle

  4. 2018
  5. Diclofenac identified as a kynurenine 3-monooxygenase binder and inhibitor by molecular similarity techniques

    Shave, S., McGuire, K., Pham, N., Mole, D., Webster, S. & Auer, M., 2 Mar 2018, In : ACS Omega.

    Research output: Contribution to journalArticle

  6. Exploring N-acyl-4-azatetracyclo[5.3.2.0.0]dodec-11-enes as 11β-HSD1 Inhibitors

    Leiva, R., McBride, A., Binnie, M., Webster, S. P. & Vázquez, S., 28 Feb 2018, In : Molecules. 23, 3

    Research output: Contribution to journalArticle

  7. 2017
  8. Detecting Drug-Target Binding in Cells using Fluorescence Activated Cell Sorting Coupled with Mass Spectrometry Analysis

    Wilson, K., Webster, S. P., Iredale, J. P., Zheng, X., Homer, N. Z. M., Pham, N., Auer, M. & Mole, D. J., 18 Dec 2017, In : Methods and Applications in Fluorescence.

    Research output: Contribution to journalArticle

  9. In search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis

    McBride, A., Hoy, A. M., Bamford, M. J., Mossakowska, D. E., Ruediger, M. P., Griggs, J., Desai, S., Simpson, K., Caballero-Hernandez, I., Iredale, J. P., Pell, T., Aucott, R. L., Holmes, D. S., Webster, S. P. & Fallowfield, J. A., 7 Sep 2017, In : Scientific Reports. 7, 1, p. 10806

    Research output: Contribution to journalArticle

  10. Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction

    Leiva, R., Griñan-Ferré, C., Seira, C., Valverde, E., McBride, A., Binnie, M., Pérez, B., Luque, F. J., Pallàs, M., Bidon-Chanal, A., Webster, S. P. & Vázquez, S., 4 Aug 2017, In : European Journal of Medicinal Chemistry. 139, p. 412-428 17 p.

    Research output: Contribution to journalArticle

  11. Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase

    Hutchinson, J. P., Rowland, P., Taylor, M. R. D., Christodoulou, E. M., Haslam, C., Hobbs, C. M., Holmes, D., Liddle, J., Mole, D., Uings, I. J., Walker, A. L., Webster, S., Mowat, C. & Chung, C., 12 Jun 2017, In : Nature Communications.

    Research output: Contribution to journalArticle

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