Edinburgh Research Explorer

Prof Seth Grant

Personal Chair of Molecular Neuroscience

  1. PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors

    Abbas, A. I., Yadav, P. N., Yao, W-D., Arbuckle, M. I., Grant, S. G. N., Caron, M. G. & Roth, B. L., 3 Jun 2009, In : Journal of Neuroscience. 29, 22, p. 7124-7136 13 p.

    Research output: Contribution to journalArticle

  2. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment

    Arbuckle, M. I., Komiyama, N. H., Delaney, A., Coba, M., Garry, E. M., Rosie, R., Allchorne, A. J., Forsyth, L. H., Bence, M., Carlisle, H. J., O'Dell, T. J., Mitchell, R., Fleetwood-Walker, S. M. & Grant, S., Jun 2010, In : EMBO Reports. 11, 6, p. 473-478 6 p.

    Research output: Contribution to journalArticle

  3. Reconstructing protein complexes: From proteomics to systems biology

    Armstrong, J. D., Pocklington, A. J., Cumiskey, M. A. & Grant, S. G. N., 2006, In : Proteomics. 6, 17, p. 4724-4731 8 p.

    Research output: Contribution to journalArticle

  4. Evolution of the synapse proteome

    Armstrong, J. D., Malik, B., Pocklington, A., Emes, R. & Grant, S., 2009, In : Journal of neurogenetics. 23, p. S34-S35 2 p.

    Research output: Contribution to journalMeeting abstract

  5. Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, A., Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, H., Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, K., 15 May 2019, In : Neuropharmacology. 150

    Research output: Contribution to journalArticle

  6. Convergence of hippocampal pathophysiology in Syngap+/- and Fmr1-/y mice

    Barnes, S., Wijetunge, L., Jackson, A. D., Katsanevaki, D., Osterweil, E., Komiyama, N., Grant, S., Bear, M. F., Nägerl, U. V., Kind, P. & Wyllie, D., 11 Nov 2015, In : Journal of Neuroscience. 35, 45, p. 15073-15081

    Research output: Contribution to journalArticle

  7. Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice

    Barnett, M. W., Watson, R. F., Vitalis, T., Porter, K., Komiyama, N. H., Stoney, P. N., Gillingwater, T. H., Grant, S. G. N. & Kind, P. C., 2006, In : Journal of Neuroscience. 26, 5, p. 1355-65 11 p.

    Research output: Contribution to journalArticle

  8. Characterization of the proteome, diseases and evolution of the human postsynaptic density

    Bayes, A., Van De Lagemaat, L., Collins, M. O., Croning, M. D. R., Whittle, I. R., Choudhary, J. S. & Grant, S. G. N., Jan 2011, In : Nature Neuroscience. 14, 1, p. 19-21 3 p.

    Research output: Contribution to journalArticle

  9. Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

    Bayes, A., Collins, M. O., Croning, M. D. R., Van De Lagemaat, L., Choudhary, J. S. & Grant, S. G. N., 5 Oct 2012, In : PLoS ONE. 7, 10, p. - 13 p., e46683.

    Research output: Contribution to journalArticle

  10. Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes

    Bayés, A., Collins, M. O., Galtrey, C. M., Simonnet, C., Roy, M., Croning, M., Gou, G., van de Lagemaat, L. N., Milward, D., Whittle, I. R., Smith, C., Choudhary, J. S. & Grant, S., 28 Nov 2014, In : Molecular brain research. 7, 1, p. 88

    Research output: Contribution to journalArticle

  11. Evolution of complexity in the zebrafish synapse proteome

    Bayés, À., Collins, M. O., Reig-viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J. S., Emes, R. D. & Grant, S. G. N., 2 Mar 2017, In : Nature Communications. 8, 14613.

    Research output: Contribution to journalArticle

  12. Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation

    Benevento, M., Oomen, C. A., Horner, A. E., Amiri, H., Jacobs, T., Pauwels, C., Frega, M., Kleefstra, T., Kopanitsa, M. V., Grant, S., Bussey, T. J., Saksida, L. M., Van der Zee, C. E. E. M., van Bokhoven, H., Glennon, J. C. & Kasri, N. N., 10 Jan 2017, In : Scientific Reports.

    Research output: Contribution to journalArticle

  13. PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits

    Broadhead, M. J., Horrocks, M. H., Zhu, F., Muresan, L., Benavides-Piccione, R., DeFelipe, J., Fricker, D., Kopanitsa, M. V., Duncan, R. R., Klenerman, D., Komiyama, N. H., Lee, S. F. & Grant, S. G. N., 25 Apr 2016, In : Scientific Reports. 6, p. 24626

    Research output: Contribution to journalArticle

  14. Regional localization of the murine Duchenne muscular dystrophy gene on the mouse X chromosome

    Chamberlain, J. S., Grant, S. G., Reeves, A. A., Mullins, L. J., Stephenson, D. A., Hoffman, E. P., Monaco, A. P., Kunkel, L. M., Caskey, C. T. & Chapman, V. M., Nov 1987, In : Somatic Cell and Molecular Genetics. 13, 6, p. 671-8 8 p.

    Research output: Contribution to journalArticle

  15. Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures

    Charlesworth, P., Cotterill, E., Morton, A., Grant, S. G. N. & Eglen, S. J., 28 Jan 2015, In : Neural Development. 10, p. 1

    Research output: Contribution to journalArticle

  16. Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns

    Charlesworth, P., Morton, A., Eglen, S. J., Komiyama, N. H. & Grant, S. G. N., 26 Jul 2015, In : Neuropharmacology.

    Research output: Contribution to journalArticle

  17. Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks

    Coba, M. P., Pocklington, A. J., Collins, M. O., Kopanitsa, M. V., Uren, R. T., Swamy, S., Croning, M. D. R., Choudhary, J. S. & Grant, S. G. N., Apr 2009, In : Science Signaling. 2, 68, ra19.

    Research output: Contribution to journalArticle

  18. Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

    Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A. & Dulawa, S. C., 2 Feb 2018, In : Scientific Reports. 8, 1

    Research output: Contribution to journalArticle

  19. TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function

    Coba, M. P., Komiyama, N. H., Nithianantharajah, J., Kopanitsa, M. V., Indersmitten, T., Skene, N. G., Tuck, E. J., Fricker, D. G., Elsegood, K. A., Stanford, L. E., Afinowi, N. O., Saksida, L. M., Bussey, T. J., O'Dell, T. J. & Grant, S. G. N., 3 Oct 2012, In : Journal of Neuroscience. 32, 40, p. 13987-13999 13 p.

    Research output: Contribution to journalArticle

  20. Altered Thalamocortical Development in the SAP102 Knockout Model of Intellectual Disability

    Crocker-Buque, A., Currie, S. P., Luz, L. L., Grant, S. G., Duffy, K. R., Kind, P. C. & Daw, M. I., 27 Jul 2016, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

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