Edinburgh Research Explorer

Seth Grant

Personal Chair of Molecular Neuroscience

  1. Association of Mouse Dlg4 (PSD-95) Gene Deletion and Human DLG4 Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams' Syndrome

    Feyder, M., Karlsson, R-M., Mathur, P., Lyman, M., Bock, R., Momenan, R., Munasinghe, J., Scattoni, M. L., Ihne, J., Camp, M., Graybeal, C., Strathdee, D., Begg, A., Alvarez, V. A., Kirsch, P., Rietschel, M., Cichon, S., Walter, H., Meyer-Lindenberg, A., Grant, S. G. N. & 1 others, Holmes, A., Dec 2010, In : American Journal of Psychiatry. 167, 12, p. 1508-1517 10 p.

    Research output: Contribution to journalArticle

  2. Durable fear memories require PSD-95

    Fitzgerald, P. J., Pinard, C. R., Camp, M. C., Feyder, M., Sah, A., Bergstrom, H. C., Graybeal, C., Liu, Y., Schlüter, O. M., Grant, S. G., Singewald, N., Xu, W. & Holmes, A., Jul 2015, In : Molecular Psychiatry. 20, 7, p. 901-12 12 p.

    Research output: Contribution to journalArticle

  3. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation

    Frank, R. A. W., Komiyama, N. H., Ryan, T. J., Zhu, F., O'Dell, T. J. & Grant, S. G. N., 27 Apr 2016, In : Nature Communications. 7, p. 11264

    Research output: Contribution to journalArticle

  4. Hierarchical organisation and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

    Frank, R. A. W., Zhu, F., Komiyama, N. H. & Grant, S. G. N., 28 Apr 2017, In : Journal of Neurochemistry.

    Research output: Contribution to journalArticle

  5. Supramolecular organization of NMDA receptors and the postsynaptic density

    Frank, R. A. & Grant, S. G., Aug 2017, In : Current Opinion in Neurobiology. 45, p. 139-147 9 p.

    Research output: Contribution to journalArticle

  6. De novo mutations in schizophrenia implicate synaptic networks

    Fromer, M., Pocklington, A. J., Kavanagh, D. H., Williams, H. J., Dwyer, S., Gormley, P., Georgieva, L., Rees, E., Palta, P., Ruderfer, D. M., Carrera, N., Humphreys, I., Johnson, J. S., Roussos, P., Barker, D. D., Banks, E., Milanova, V., Grant, S. G., Hannon, E., Rose, S. A. & 12 others, Chambert, K., Mahajan, M., Scolnick, E. M., Moran, J. L., Kirov, G., Palotie, A., McCarroll, S. A., Holmans, P., Sklar, P., Owen, M. J., Purcell, S. M. & O'Donovan, M. C., 13 Feb 2014, In : Nature. 506, 7487, p. 179-+ 16 p.

    Research output: Contribution to journalArticle

  7. Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases

    Grant, S. G. N., Marshall, M. C., Page, K-L., Cumiskey, M. A. & Armstrong, J. D., 2005, In : Human Molecular Genetics. 14, suppl 2, p. R225-R234 10 p.

    Research output: Contribution to journalArticle

  8. Synaptopathy - From biology to therapy

    Grant, S. G. N., Bagni, C. & O'Dell, T. J., 1 Jan 2016, In : Neuropharmacology. 100, p. 1 1 p.

    Research output: Contribution to journalEditorial

  9. Synapse diversity and synaptome architecture in human genetic disorders

    Grant, S. G. N., 26 Jul 2019, In : Human Molecular Genetics.

    Research output: Contribution to journalReview article

  10. The molecular evolution of the vertebrate behavioural repertoire

    Grant, S. G. N., 5 Jan 2016, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 371, 1685, 20150051.

    Research output: Contribution to journalArticle

  11. The Organization and integrative function of the post-synaptic proteome

    Grant, S., Husi, H., Choudhary, J., Cumiskey, M., Blackstock, W. & Armstrong, D., 2004, Excitatory-Inhibitory Balance: Synapses, Circuits, Systems. KLUWER ACADEMIC/PLENUM PUBL, p. 13-44 32 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  12. Synaptopathies: diseases of the synaptome

    Grant, S. G., 2012, In : Current Opinion in Neurobiology.

    Research output: Contribution to journalArticle

  13. Synapse molecular complexity and the plasticity-behaviour problem

    Grant, S., 15 Nov 2018, In : Brain and Neuroscience Advances.

    Research output: Contribution to journalArticle

  14. SnapShot: Organizational principles of the postsynaptic proteome

    Grant, S. G. N., 16 Oct 2013, In : Neuron. 80, 2, p. 534.e1

    Research output: Contribution to journalArticle

  15. The Synapse Diversity Dilemma: Molecular Heterogeneity Confounds Studies of Synapse Function

    Grant, S. G. N. & Fransén, E., 2 Oct 2020, In : Frontiers in synaptic neuroscience. 12

    Research output: Contribution to journalArticle

  16. The Synaptomic Theory of Behavior and Brain Disease

    Grant, S. G. N., 18 Mar 2019, In : Cold Spring Harbor Symposia on Quantitative Biology. p. 037887

    Research output: Contribution to journalArticle

  17. FAK is required for axonal sorting by Schwann cells

    Grove, M., Komiyama, N. H., Nave, K-A., Grant, S. G., Sherman, D. L. & Brophy, P. J., 2007, In : Journal of Cell Biology. 176, 3, p. 277-82 6 p.

    Research output: Contribution to journalArticle

  18. An anatomically comprehensive atlas of the adult human brain transcriptome

    Hawrylycz, M. J., Lein, E. S., Guillozet-Bongaarts, A. L., Shen, E. H., Ng, L., Miller, J. A., Van De Lagemaat, L., Smith, K. A., Ebbert, A., Riley, Z. L., Abajian, C., Beckmann, C. F., Bernard, A., Bertagnolli, D., Boe, A. F., Cartagena, P. M., Chakravarty, M. M., Chapin, M., Chong, J., Dalley, R. A. & 47 others, Daly, B. D., Dang, C., Datta, S., Dee, N., Dolbeare, T. A., Faber, V., Feng, D., Fowler, D. R., Goldy, J., Gregor, B. W., Haradon, Z., Haynor, D. R., Hohmann, J. G., Horvath, S., Howard, R. E., Jeromin, A., Jochim, J. M., Kinnunen, M., Lau, C., Lazarz, E. T., Lee, C., Lemon, T. A., Li, L., Li, Y., Morris, J. A., Overly, C. C., Parker, P. D., Parry, S. E., Reding, M., Royall, J. J., Schulkin, J., Sequeira, P. A., Slaughterbeck, C. R., Smith, S. C., Sodt, A. J., Sunkin, S. M., Swanson, B. E., Vawter, M. P., Williams, D., Wohnoutka, P., Zielke, H. R., Geschwind, D. H., Hof, P. R., Smith, S. M., Koch, C., Grant, S. G. N. & Jones, A. R., 2012, In : Nature. 489, 7416, p. 391-399 9 p.

    Research output: Contribution to journalArticle

  19. Human cognitive ability is influenced by genetic variation in components of postsynaptic signaling complexes assembled by MAGUK proteins

    Hill, W. D., Davies, G., Van de Lagemaat, L., Christoforou, A., Fernandes, C., Liewald, D., Croning, M., Payton, A., Craig, L., Whalley, L., Horan, M., Ollier, W., Hansell, N., Wright, M., Martin, N. G., Montgomery, G., Steen, V., Le Hellard, S., Espeseth, T., Lundervold, A. & 6 others, Reinvang, I., Starr, J., Pendleton, N., Grant, S., Bates, T. & Deary, I., Nov 2013, In : Behavior Genetics. 43, 6, p. 521-522 2 p.

    Research output: Contribution to journalMeeting abstract

  20. Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

    Hill, W. D., Davies, G., Van De Lagemaat, L. N., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S., Espeseth, T. & 7 others, Lundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C. & Deary, I. J., 7 Jan 2014, In : Translational Psychiatry. 4, 1, 8 p., 341.

    Research output: Contribution to journalArticle