Edinburgh Research Explorer

Seth Grant

Personal Chair of Molecular Neuroscience

  1. Cognitive components in mice and humans: Combining genetics and touchscreens for medical translation

    Nithianantharajah, J. & Grant, S. G. N., Oct 2013, In : Neurobiology of Learning and Memory. 105, p. 13-19 7 p.

    Research output: Contribution to journalArticle

  2. Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

    Bayes, A., Collins, M. O., Croning, M. D. R., Van De Lagemaat, L., Choudhary, J. S. & Grant, S. G. N., 5 Oct 2012, In : PLoS ONE. 7, 10, p. - 13 p., e46683.

    Research output: Contribution to journalArticle

  3. Comprehensive behavioral analysis of heterozygous Syngap1knockout mice

    Nakajima, R., Takao, K., Hattori, S., Shoji, H., Komiyama, N. H., Grant, S. G. N. & Miyakawa, T., 19 Jul 2019, In : Neuropsychopharmacology Reports.

    Research output: Contribution to journalArticle

  4. Computational geometry analysis of dendritic spines by structured illumination microscopy

    Kashiwagi, Y., Higashi, T., Obashi, K., Sato, Y., Komiyama, N. H., Grant, S. G. N. & Okabe, S., 20 Mar 2019, In : Nature Communications. 10, 1

    Research output: Contribution to journalArticle

  5. Convergence of hippocampal pathophysiology in Syngap+/- and Fmr1-/y mice

    Barnes, S., Wijetunge, L., Jackson, A. D., Katsanevaki, D., Osterweil, E., Komiyama, N., Grant, S., Bear, M. F., Nägerl, U. V., Kind, P. & Wyllie, D., 11 Nov 2015, In : Journal of Neuroscience. 35, 45, p. 15073-15081

    Research output: Contribution to journalArticle

  6. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

    Kirov, G., Pocklington, A. J., Holmans, P., Ivanov, D., Ikeda, M., Ruderfer, D., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., Grozeva, D., Fjodorova, M., Wollerton, R., Rees, E., Nikolov, I., Van De Lagemaat, L., Bayés, A., Fernandez, E., Olason, P. I., Böttcher, Y. & 10 others, Komiyama, N. H., Collins, M. O., Choudhary, J., Stefansson, K., Stefansson, H., Grant, S. G. N., Purcell, S., Sklar, P., O'Donovan, M. C. & Owen, M. J., Feb 2012, In : Molecular Psychiatry. 17, 2, p. 142-153 12 p.

    Research output: Contribution to journalArticle

  7. De novo mutations in schizophrenia implicate synaptic networks

    Fromer, M., Pocklington, A. J., Kavanagh, D. H., Williams, H. J., Dwyer, S., Gormley, P., Georgieva, L., Rees, E., Palta, P., Ruderfer, D. M., Carrera, N., Humphreys, I., Johnson, J. S., Roussos, P., Barker, D. D., Banks, E., Milanova, V., Grant, S. G., Hannon, E., Rose, S. A. & 12 others, Chambert, K., Mahajan, M., Scolnick, E. M., Moran, J. L., Kirov, G., Palotie, A., McCarroll, S. A., Holmans, P., Sklar, P., Owen, M. J., Purcell, S. M. & O'Donovan, M. C., 13 Feb 2014, In : Nature. 506, 7487, p. 179-+ 16 p.

    Research output: Contribution to journalArticle

  8. Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

    Van Campenhout, C. A., Eitelhuber, A., Gloeckner, C. J., Giallonardo, P., Gegg, M., Oller, H., Grant, S. G. N., Krappmann, D., Ueffing, M. & Lickert, H., 13 Sep 2011, In : Developmental Cell. 21, 3, p. 479-491 13 p.

    Research output: Contribution to journalArticle

  9. Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

    Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A. & Dulawa, S. C., 2 Feb 2018, In : Scientific Reports. 8, 1

    Research output: Contribution to journalArticle

  10. Durable fear memories require PSD-95

    Fitzgerald, P. J., Pinard, C. R., Camp, M. C., Feyder, M., Sah, A., Bergstrom, H. C., Graybeal, C., Liu, Y., Schlüter, O. M., Grant, S. G., Singewald, N., Xu, W. & Holmes, A., Jul 2015, In : Molecular Psychiatry. 20, 7, p. 901-12 12 p.

    Research output: Contribution to journalArticle

  11. Efficient linkage of 10 loci in the proximal region of the mouse X chromosome

    Mullins, L. J., Stephenson, D. A., Grant, S. G. & Chapman, V. M., May 1990, In : Genomics. 7, 1, p. 19-30 12 p.

    Research output: Contribution to journalArticle

  12. Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95

    Horner, A. E., McLaughlin, C. L., Afinowi, N. O., Bussey, T. J., Saksida, L. M., Komiyama, N. H., Grant, S. G. N. & Kopanitsa, M. V., 13 Dec 2017, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  13. Estimation of the number of synapses in the hippocampus and brain-wide by volume electron microscopy and genetic labeling

    Santuy, A., Tomás-roca, L., Rodríguez, J., González-soriano, J., Zhu, F., Qiu, Z., Grant, S. G. N., Defelipe, J. & Merchan-perez, A., 19 Aug 2020, In : Scientific Reports. 10, 1

    Research output: Contribution to journalArticle

  14. Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

    Ryan, T. J., Kopanitsa, M. V., Indersmitten, T., Nithianantharajah, J., Afinowi, N. O., Pettit, C., Stanford, L. E., Sprengel, R., Saksida, L. M., Bussey, T. J., O'Dell, T. J., Grant, S. G. N. & Komiyama, N., 2013, In : Nature Neuroscience. 16, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  15. Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes

    Ryan, T. J., Emes, R. D., Grant, S. G. & Komiyama, N. H., 2008, In : BMC Neuroscience. 9, p. 6

    Research output: Contribution to journalArticle

  16. Evolution of Synapse Complexity and Diversity

    Emes, R. D. & Grant, S. G. N., 2012, ANNUAL REVIEW OF NEUROSCIENCE, VOL 35. Hyman, SE. (ed.). PALO ALTO: ANNUAL REVIEWS, p. 111-131 21 p. (Annual Review of Neuroscience; vol. 35).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  17. Evolution of complexity in the zebrafish synapse proteome

    Bayés, À., Collins, M. O., Reig-viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J. S., Emes, R. D. & Grant, S. G. N., 2 Mar 2017, In : Nature Communications. 8, 14613.

    Research output: Contribution to journalArticle

  18. Evolution of the synapse proteome

    Armstrong, J. D., Malik, B., Pocklington, A., Emes, R. & Grant, S., 2009, In : Journal of neurogenetics. 23, p. S34-S35 2 p.

    Research output: Contribution to journalMeeting abstract

  19. Evolutionary expansion and anatomical specialization of synapse proteome complexity

    Emes, R. D., Pocklington, A. J., Anderson, C. N. G., Bayes, A., Collins, M. O., Vickers, C. A., Croning, M. D. R., Malik, B. R., Choudhary, J. S., Armstrong, D. & Grant, S., Jul 2008, In : Nature Neuroscience. 11, 7, p. 799-806 8 p.

    Research output: Contribution to journalArticle