Edinburgh Research Explorer

Prof Seth Grant

Personal Chair of Molecular Neuroscience

  1. 2020
  2. A brain-wide atlas of synapses across the mouse lifespan

    Cizeron, M., Qiu, Z., Koniaris, B., Gokhale, R., Komiyama, N. H., Fransén, E. & Grant, S. G. N., 11 Jun 2020, In : Science. p. eaba3163

    Research output: Contribution to journalArticle

  3. A single‐synapse resolution survey of PSD95‐positive synapses in twenty human brain regions

    Curran, O. E., Qiu, Z., Smith, C. & Grant, S. G. N., 3 Jun 2020, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  4. Nanostructural Diversity of Synapses in the Mammalian Spinal Cord

    Broadhead, M. J., Bonthron, C., Arcinas, L., Bez, S., Zhu, F., Goff, F., Nylk, J., Dholakia, K., Gunn-moore, F., Grant, S. G. N. & Miles, G. B., 18 May 2020, In : Scientific Reports. 10, 1

    Research output: Contribution to journalArticle

  5. 2019
  6. Cell‐type specific visualization and biochemical isolation of endogenous synaptic proteins in mice

    Zhu, F., Collins, M. O., Harmse, J., Choudhary, J. S., Grant, S. G. N. & Komiyama, N. H., 16 Oct 2019, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  7. NMDA receptor modulation of glutamate release in activated neutrophils

    Del Arroyo, A. G., Hadjihambi, A., Sanchez, J., Turovsky, E., Kasymov, V., Cain, D., Nightingale, T. D., Lambden, S., Grant, S. G. N., Gourine, A. V. & Ackland, G. L., 8 Aug 2019, In : EBioMedicine.

    Research output: Contribution to journalArticle

  8. Synapse diversity and synaptome architecture in human genetic disorders

    Grant, S. G. N., 26 Jul 2019, In : Human Molecular Genetics.

    Research output: Contribution to journalReview article

  9. Comprehensive behavioral analysis of heterozygous Syngap1knockout mice

    Nakajima, R., Takao, K., Hattori, S., Shoji, H., Komiyama, N. H., Grant, S. G. N. & Miyakawa, T., 19 Jul 2019, In : Neuropsychopharmacology Reports.

    Research output: Contribution to journalArticle

  10. Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, A., Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, H., Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, K., 15 May 2019, In : Neuropharmacology. 150

    Research output: Contribution to journalArticle

  11. Computational geometry analysis of dendritic spines by structured illumination microscopy

    Kashiwagi, Y., Higashi, T., Obashi, K., Sato, Y., Komiyama, N. H., Grant, S. G. N. & Okabe, S., 20 Mar 2019, In : Nature Communications. 10, 1

    Research output: Contribution to journalArticle

  12. The Synaptomic Theory of Behavior and Brain Disease

    Grant, S. G. N., 18 Mar 2019, In : Cold Spring Harbor Symposia on Quantitative Biology. p. 037887

    Research output: Contribution to journalArticle

  13. 2018
  14. Synapse molecular complexity and the plasticity-behaviour problem

    Grant, S., 15 Nov 2018, In : Brain and Neuroscience Advances.

    Research output: Contribution to journalArticle

  15. Rapid homeostatic downregulation of LTP by extrasynaptic GluN2B receptors

    Delgado, J. Y., Fink, A. E., Grant, S. G. N., O'Dell, T. J. & Opazo, P., Nov 2018, In : Journal of Neurophysiology.

    Research output: Contribution to journalArticle

  16. Architecture of the Mouse Brain Synaptome

    Zhu, F., Cizeron, M., Qiu, Z., Benavides-piccione, R., Kopanitsa, M. V., Skene, N. G., Koniaris, B., Defelipe, J., Fransén, E., Komiyama, N. H. & Grant, S. G. N., 2 Aug 2018, In : Neuron.

    Research output: Contribution to journalArticle

  17. Regional Diversity in the Postsynaptic Proteome of the Mouse Brain

    Roy, M., Sorokina, O., McLean, C., Tapia-González, S., DeFelipe, J., Armstrong, J. D. & Grant, S., 1 Aug 2018, In : Proteomes. 6, 3, 18 p.

    Research output: Contribution to journalArticle

  18. Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1 mice

    Kopanitsa, M. V., Gou, G., Afinowi, N. O., Bayés, À., Grant, S. G. N. & Komiyama, N. H., Aug 2018, In : Pharmacological reports. 70, 4, p. 777-783 7 p.

    Research output: Contribution to journalArticle

  19. Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

    Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A. & Dulawa, S. C., 2 Feb 2018, In : Scientific Reports. 8, 1

    Research output: Contribution to journalArticle

  20. In vivo STED microscopy visualizes morphological changes of large PSD95 assemblies over several hours in the mouse visual cortex

    Wegner, W., Mott, A. C., Grant, S., Steffens, H. & Willig, K. I., 9 Jan 2018, In : Scientific Reports.

    Research output: Contribution to journalArticle

  21. 2017
  22. Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95

    Horner, A. E., McLaughlin, C. L., Afinowi, N. O., Bussey, T. J., Saksida, L. M., Komiyama, N. H., Grant, S. G. N. & Kopanitsa, M. V., 13 Dec 2017, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  23. Proteomic analysis of postsynaptic proteins in regions of the human neocortex

    Roy, M., Sorokina, O., Skene, N., Simonnet, C., Mazzola, F., Zwart, R., Sher, E., Smith, C., Armstrong, J. D. & Grant, S., 4 Dec 2017, In : Nature Neuroscience.

    Research output: Contribution to journalArticle

  24. Arc requires PSD95 for assembly into postsynaptic complexes involved with brain disease and intelligence

    Fernandez, E., Collins, M. O., Frank, R. A. W., Zhu, F., Kopanitsa, M. V., Nithianantharajah, J., Lempriere, S., Fricker, D. G., Elsegood, K. A., McLaughlin, C., Croning, M. D. R., McLean, C., Armstrong, J. D., Hill, W. D., Deary, I., Cencelli, G., Bagni, C., Fromer, M., Purcell, S. M., Pocklington, A. J. & 3 others, Choudhary, J. S., Komiyama, N. & Grant, S., 17 Oct 2017, In : Cell Reports. 21, 3, p. 679-691

    Research output: Contribution to journalArticle

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