Edinburgh Research Explorer

Prof Seth Grant

Personal Chair of Molecular Neuroscience

  1. 2019
  2. Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, A., Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, H., Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, K., 15 May 2019, In : Neuropharmacology. 150

    Research output: Contribution to journalArticle

  3. Computational geometry analysis of dendritic spines by structured illumination microscopy

    Kashiwagi, Y., Higashi, T., Obashi, K., Sato, Y., Komiyama, N. H., Grant, S. G. N. & Okabe, S., 20 Mar 2019, In : Nature Communications. 10, 1

    Research output: Contribution to journalArticle

  4. The Synaptomic Theory of Behavior and Brain Disease

    Grant, S. G. N., 18 Mar 2019, In : Cold Spring Harbor Symposia on Quantitative Biology. p. 037887

    Research output: Contribution to journalArticle

  5. 2018
  6. Synapse molecular complexity and the plasticity-behaviour problem

    Grant, S., 15 Nov 2018, In : Brain and Neuroscience Advances.

    Research output: Contribution to journalArticle

  7. Rapid homeostatic downregulation of LTP by extrasynaptic GluN2B receptors

    Delgado, J. Y., Fink, A. E., Grant, S. G. N., O'Dell, T. J. & Opazo, P., Nov 2018, In : Journal of Neurophysiology.

    Research output: Contribution to journalArticle

  8. Architecture of the Mouse Brain Synaptome

    Zhu, F., Cizeron, M., Qiu, Z., Benavides-piccione, R., Kopanitsa, M. V., Skene, N. G., Koniaris, B., Defelipe, J., Fransén, E., Komiyama, N. H. & Grant, S. G. N., 2 Aug 2018, In : Neuron.

    Research output: Contribution to journalArticle

  9. Regional Diversity in the Postsynaptic Proteome of the Mouse Brain

    Roy, M., Sorokina, O., McLean, C., Tapia-González, S., DeFelipe, J., Armstrong, J. D. & Grant, S., 1 Aug 2018, In : Proteomes. 6, 3, 18 p.

    Research output: Contribution to journalArticle

  10. Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1 mice

    Kopanitsa, M. V., Gou, G., Afinowi, N. O., Bayés, À., Grant, S. G. N. & Komiyama, N. H., Aug 2018, In : Pharmacological reports. 70, 4, p. 777-783 7 p.

    Research output: Contribution to journalArticle

  11. Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

    Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A. & Dulawa, S. C., 2 Feb 2018, In : Scientific Reports. 8, 1

    Research output: Contribution to journalArticle

  12. In vivo STED microscopy visualizes morphological changes of large PSD95 assemblies over several hours in the mouse visual cortex

    Wegner, W., Mott, A. C., Grant, S., Steffens, H. & Willig, K. I., 9 Jan 2018, In : Scientific Reports.

    Research output: Contribution to journalArticle

  13. 2017
  14. Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95

    Horner, A. E., McLaughlin, C. L., Afinowi, N. O., Bussey, T. J., Saksida, L. M., Komiyama, N. H., Grant, S. G. N. & Kopanitsa, M. V., 13 Dec 2017, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  15. Proteomic analysis of postsynaptic proteins in regions of the human neocortex

    Roy, M., Sorokina, O., Skene, N., Simonnet, C., Mazzola, F., Zwart, R., Sher, E., Smith, C., Armstrong, J. D. & Grant, S., 4 Dec 2017, In : Nature Neuroscience.

    Research output: Contribution to journalArticle

  16. Arc requires PSD95 for assembly into postsynaptic complexes involved with brain disease and intelligence

    Fernandez, E., Collins, M. O., Frank, R. A. W., Zhu, F., Kopanitsa, M. V., Nithianantharajah, J., Lempriere, S., Fricker, D. G., Elsegood, K. A., McLaughlin, C., Croning, M. D. R., McLean, C., Armstrong, J. D., Hill, W. D., Deary, I., Cencelli, G., Bagni, C., Fromer, M., Purcell, S. M., Pocklington, A. J. & 3 othersChoudhary, J. S., Komiyama, N. & Grant, S., 17 Oct 2017, In : Cell Reports. 21, 3, p. 679-691

    Research output: Contribution to journalArticle

  17. A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia

    Skene, N. G., Roy, M. & Grant, S. G., 12 Sep 2017, In : eLIFE. 6

    Research output: Contribution to journalArticle

  18. Supramolecular organization of NMDA receptors and the postsynaptic density

    Frank, R. A. & Grant, S. G., Aug 2017, In : Current Opinion in Neurobiology. 45, p. 139-147 9 p.

    Research output: Contribution to journalArticle

  19. Hierarchical organisation and genetically separable subfamilies of PSD95 postsynaptic supercomplexes

    Frank, R. A. W., Zhu, F., Komiyama, N. H. & Grant, S. G. N., 28 Apr 2017, In : Journal of Neurochemistry.

    Research output: Contribution to journalArticle

  20. Evolution of complexity in the zebrafish synapse proteome

    Bayés, À., Collins, M. O., Reig-viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J. S., Emes, R. D. & Grant, S. G. N., 2 Mar 2017, In : Nature Communications. 8, 14613

    Research output: Contribution to journalArticle

  21. Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference

    Shukla, A., Beroun, A., Panopoulou, M., Neumann, P. A., Grant, S. G., Olive, M. F., Dong, Y. & Schlüter, O. M., 11 Jan 2017, In : EMBO Journal.

    Research output: Contribution to journalArticle

  22. Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation

    Benevento, M., Oomen, C. A., Horner, A. E., Amiri, H., Jacobs, T., Pauwels, C., Frega, M., Kleefstra, T., Kopanitsa, M. V., Grant, S., Bussey, T. J., Saksida, L. M., Van der Zee, C. E. E. M., van Bokhoven, H., Glennon, J. C. & Kasri, N. N., 10 Jan 2017, In : Scientific Reports.

    Research output: Contribution to journalArticle

  23. 2016
  24. Standardised experiments in mutant mice reveal behavioural similarity on 129S5 and C57BL/6J backgrounds

    van de Lagemaat, L. N., Stanford, L. E., Pettit, C., Strathdee, D. J., Strathdee, K. E., Elsegood, K. A., Fricker, D. G., Croning, M. D. R., Komiyama, N. H. & Grant, S. G. N., 25 Nov 2016, In : Genes Brain and Behavior.

    Research output: Contribution to journalArticle

  25. ATP from synaptic terminals and astrocytes regulates NMDA receptors and synaptic plasticity through PSD-95 multi-protein complex

    Lalo, U., Palygin, O., Verkhratsky, A., Grant, S. & Pankratov, Y., 19 Sep 2016, In : Scientific Reports. 6, 20 p., 33609

    Research output: Contribution to journalArticle

  26. Altered Thalamocortical Development in the SAP102 Knockout Model of Intellectual Disability

    Crocker-Buque, A., Currie, S. P., Luz, L. L., Grant, S. G., Duffy, K. R., Kind, P. C. & Daw, M. I., 27 Jul 2016, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

  27. Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways

    Farzana, F., Zalm, R., Chen, N., Li, K. W., Grant, S. G. N., Smit, A. B., Toonen, R. F. & Verhage, M., 2 May 2016, In : Molecular Neurobiology. 53, 4, p. 2112-2123 12 p.

    Research output: Contribution to journalArticle

  28. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation

    Frank, R. A. W., Komiyama, N. H., Ryan, T. J., Zhu, F., O'Dell, T. J. & Grant, S. G. N., 27 Apr 2016, In : Nature Communications. 7, p. 11264

    Research output: Contribution to journalArticle

  29. PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits

    Broadhead, M. J., Horrocks, M. H., Zhu, F., Muresan, L., Benavides-Piccione, R., DeFelipe, J., Fricker, D., Kopanitsa, M. V., Duncan, R. R., Klenerman, D., Komiyama, N. H., Lee, S. F. & Grant, S. G. N., 25 Apr 2016, In : Scientific Reports. 6, p. 24626

    Research output: Contribution to journalArticle

  30. Identification of vulnerable cell types in major brain disorders using single cell transcriptomes and expression weighted cell type enrichment

    Skene, N. G. & Grant, S. G. N., 27 Jan 2016, In : Frontiers in Neuroscience. 10, JAN, 16

    Research output: Contribution to journalArticle

  31. The molecular evolution of the vertebrate behavioural repertoire

    Grant, S. G. N., 5 Jan 2016, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 371, 1685, 20150051

    Research output: Contribution to journalArticle

  32. Synaptopathy - From biology to therapy

    Grant, S. G. N., Bagni, C. & O'Dell, T. J., 1 Jan 2016, In : Neuropharmacology. 100, p. 1 1 p.

    Research output: Contribution to journalEditorial

  33. 2015
  34. Convergence of hippocampal pathophysiology in Syngap+/- and Fmr1-/y mice

    Barnes, S., Wijetunge, L., Jackson, A. D., Katsanevaki, D., Osterweil, E., Komiyama, N., Grant, S., Bear, M. F., Nägerl, U. V., Kind, P. & Wyllie, D., 11 Nov 2015, In : Journal of Neuroscience. 35, 45, p. 15073-15081

    Research output: Contribution to journalArticle

  35. Bridging the translational divide: identical cognitive touchscreen testing in mice and humans carrying mutations in a disease-relevant homologous gene

    Nithianantharajah, J., McKechanie, A. G., Stewart, T. J., Johnstone, M., Blackwood, D. H., St Clair, D., Grant, S. G. N., Bussey, T. J. & Saksida, L. M., 1 Oct 2015, In : Scientific Reports. 5, p. 14613

    Research output: Contribution to journalArticle

  36. Canalization of genetic and pharmacological perturbations in developing primary neuronal activity patterns

    Charlesworth, P., Morton, A., Eglen, S. J., Komiyama, N. H. & Grant, S. G. N., 26 Jul 2015, In : Neuropharmacology.

    Research output: Contribution to journalArticle

  37. NMDA receptor subunits and associated signaling molecules mediating antidepressant-related effects of NMDA-GluN2B antagonism

    Kiselycznyk, C., Jury, N. J., Halladay, L. R., Nakazawa, K., Mishina, M., Sprengel, R., Grant, S. G. N., Svenningsson, P. & Holmes, A., 1 Jul 2015, In : Behavioural Brain Research. 287, p. 89-95 7 p.

    Research output: Contribution to journalArticle

  38. Durable fear memories require PSD-95

    Fitzgerald, P. J., Pinard, C. R., Camp, M. C., Feyder, M., Sah, A., Bergstrom, H. C., Graybeal, C., Liu, Y., Schlüter, O. M., Grant, S. G., Singewald, N., Xu, W. & Holmes, A., Jul 2015, In : Molecular Psychiatry. 20, 7, p. 901-12 12 p.

    Research output: Contribution to journalArticle

  39. Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95

    Daut, R. A., Busch, E. F., Ihne, J., Fisher, D., Mishina, M., Grant, S. G. N., Camp, M. & Holmes, A., Mar 2015, In : Addiction Biology. 20, 2, p. 259-262 4 p.

    Research output: Contribution to journalArticle

  40. Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures

    Charlesworth, P., Cotterill, E., Morton, A., Grant, S. G. N. & Eglen, S. J., 28 Jan 2015, In : Neural Development. 10, p. 1

    Research output: Contribution to journalArticle

  41. Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption

    Milner, L. C., Shirley, R. L., Kozell, L. B., Walter, N. A., Kruse, L. C., Komiyama, N. H., Grant, S. G. N. & Buck, K. J., Jan 2015, In : Addiction Biology. 20, 1, p. 143-147 5 p.

    Research output: Contribution to journalArticle

  42. 2014
  43. Human post-mortem synapse proteome integrity screening for proteomic studies of postsynaptic complexes

    Bayés, A., Collins, M. O., Galtrey, C. M., Simonnet, C., Roy, M., Croning, M., Gou, G., van de Lagemaat, L. N., Milward, D., Whittle, I. R., Smith, C., Choudhary, J. S. & Grant, S., 28 Nov 2014, In : Molecular brain research. 7, 1, p. 88

    Research output: Contribution to journalArticle

  44. A polygenic burden of rare disruptive mutations in schizophrenia

    Purcell, S. M., Moran, J. L., Fromer, M., Ruderfer, D., Solovieff, N., Roussos, P., O'Dushlaine, C., Chambert, K., Bergen, S. E., Kahler, A., Duncan, L., Stahl, E., Genovese, G., Fernandez, E., Collins, M. O., Komiyama, N. H., Choudhary, J. S., Magnusson, P. K. E., Banks, E., Shakir, K. & 12 othersGarimella, K., Fennell, T., DePristo, M., Grant, S. G. N., Haggarty, S. J., Gabriel, S., Scolnick, E. M., Lander, E. S., Hultman, C. M., Sullivan, P. F., McCarroll, S. A. & Sklar, P., 13 Feb 2014, In : Nature. 506, 7487, p. 185-+ 17 p.

    Research output: Contribution to journalArticle

  45. De novo mutations in schizophrenia implicate synaptic networks

    Fromer, M., Pocklington, A. J., Kavanagh, D. H., Williams, H. J., Dwyer, S., Gormley, P., Georgieva, L., Rees, E., Palta, P., Ruderfer, D. M., Carrera, N., Humphreys, I., Johnson, J. S., Roussos, P., Barker, D. D., Banks, E., Milanova, V., Grant, S. G., Hannon, E., Rose, S. A. & 12 othersChambert, K., Mahajan, M., Scolnick, E. M., Moran, J. L., Kirov, G., Palotie, A., McCarroll, S. A., Holmans, P., Sklar, P., Owen, M. J., Purcell, S. M. & O'Donovan, M. C., 13 Feb 2014, In : Nature. 506, 7487, p. 179-+ 16 p.

    Research output: Contribution to journalArticle

  46. Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins

    Hill, W. D., Davies, G., Van De Lagemaat, L., Christoforou, A., Marioni, R. E., Fernandes, C. P. D., Liewald, D. C., Croning, M. D. R., Payton, A., Craig, L. C. A., Whalley, L. J., Horan, M., Ollier, W., Hansell, N. K., Wright, M. J., Martin, N. G., Montgomery, G. W., Steen, V. M., Le Hellard, S., Espeseth, T. & 7 othersLundervold, A. J., Reinvang, I., Starr, J. M., Pendleton, N., Grant, S. G. N., Bates, T. C. & Deary, I. J., 7 Jan 2014, In : Translational Psychiatry. 4, 1, 8 p., 341

    Research output: Contribution to journalArticle

  47. 2013
  48. Human cognitive ability is influenced by genetic variation in components of postsynaptic signaling complexes assembled by MAGUK proteins

    Hill, W. D., Davies, G., Van de Lagemaat, L., Christoforou, A., Fernandes, C., Liewald, D., Croning, M., Payton, A., Craig, L., Whalley, L., Horan, M., Ollier, W., Hansell, N., Wright, M., Martin, N. G., Montgomery, G., Steen, V., Le Hellard, S., Espeseth, T., Lundervold, A. & 6 othersReinvang, I., Starr, J., Pendleton, N., Grant, S., Bates, T. & Deary, I., Nov 2013, In : Behavior Genetics. 43, 6, p. 521-522 2 p.

    Research output: Contribution to journalMeeting abstract

  49. SnapShot: Organizational principles of the postsynaptic proteome

    Grant, S. G. N., 16 Oct 2013, In : Neuron. 80, 2, p. 534.e1

    Research output: Contribution to journalArticle

  50. Cognitive components in mice and humans: Combining genetics and touchscreens for medical translation

    Nithianantharajah, J. & Grant, S. G. N., Oct 2013, In : Neurobiology of Learning and Memory. 105, p. 13-19 7 p.

    Research output: Contribution to journalArticle

  51. CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

    De Rubeis, S., Pasciuto, E., Li, K. W., Fernández, E., Di Marino, D., Buzzi, A., Ostroff, L. E., Klann, E., Zwartkruis, F. J. T., Komiyama, N. H., Grant, S. G. N., Poujol, C., Choquet, D., Achsel, T., Posthuma, D., Smit, A. B. & Bagni, C., 18 Sep 2013, In : Neuron. 79, 6, p. 1169-82 14 p.

    Research output: Contribution to journalArticle

  52. Probing the Modulation of Acute Ethanol Intoxication by Pharmacological Manipulation of the NMDAR Glycine Co-Agonist Site

    DeBrouse, L., Hurd, B., Kiselycznyk, C., Plitt, A., Todaro, A., Mishina, M., Grant, S. G. N., Camp, M., Gunduz-Cinar, O. & Holmes, A., Feb 2013, In : Alcoholism-Clinical and experimental research. 37, 2, p. 223-233 11 p.

    Research output: Contribution to journalArticle

  53. SynSysNet: integration of experimental data on synaptic protein-protein interactions with drug-target relations

    von Eichborn, J., Dunkel, M., Gohlke, B. O., Preissner, S. C., Hoffmann, M. F., Bauer, J. M. J., Armstrong, D., Schaefer, M. H., Andrade-Navarro, M. A., Le Novere, N., Croning, M. D. R., Grant, S. G. N., van Nierop, P., Smit, A. B. & Preissner, R., Jan 2013, In : Nucleic Acids Research. 41, D1, p. D834-D840 7 p.

    Research output: Contribution to journalArticle

  54. Synaptic scaffold evolution generated components of vertebrate cognitive complexity

    Nithianantharajah, J., Komiyama, N., McKechanie, A., Johnstone, M., Blackwood, D. H., Clair, D. S., Emes, R. D., van de Lagemaat, L. N., Saksida, L. M., Bussey, T. J. & Grant, S. G. N., Jan 2013, In : Nature Neuroscience. 16, 1, p. 16-24 9 p.

    Research output: Contribution to journalArticle

  55. Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

    Ryan, T. J., Kopanitsa, M. V., Indersmitten, T., Nithianantharajah, J., Afinowi, N. O., Pettit, C., Stanford, L. E., Sprengel, R., Saksida, L. M., Bussey, T. J., O'Dell, T. J., Grant, S. G. N. & Komiyama, N., 2013, In : Nature Neuroscience. 16, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  56. 2012
  57. The association between cognitive abilities and the postsynaptic proteome of central excitatory synapses

    Hill, W. D., Davies, G., Croning, M., Payton, A., Craig, L., Horan, M., Ollier, WI., Starr, J., Pendleton, N., Grant, S., Bates, T. & Deary, I., Nov 2012, In : Behavior Genetics. 42, 6, p. 938-938 1 p.

    Research output: Contribution to journalMeeting abstract

  58. Comparative Study of Human and Mouse Postsynaptic Proteomes Finds High Compositional Conservation and Abundance Differences for Key Synaptic Proteins

    Bayes, A., Collins, M. O., Croning, M. D. R., Van De Lagemaat, L., Choudhary, J. S. & Grant, S. G. N., 5 Oct 2012, In : PLoS ONE. 7, 10, p. - 13 p., e46683

    Research output: Contribution to journalArticle

  59. TNiK Is Required for Postsynaptic and Nuclear Signaling Pathways and Cognitive Function

    Coba, M. P., Komiyama, N. H., Nithianantharajah, J., Kopanitsa, M. V., Indersmitten, T., Skene, N. G., Tuck, E. J., Fricker, D. G., Elsegood, K. A., Stanford, L. E., Afinowi, N. O., Saksida, L. M., Bussey, T. J., O'Dell, T. J. & Grant, S. G. N., 3 Oct 2012, In : Journal of Neuroscience. 32, 40, p. 13987-13999 13 p.

    Research output: Contribution to journalArticle

  60. Genetic Dissection Of Cognition In Humans And Mice Carrying Mutations: Evidence That Vertebrate Genomic Evolution Produced Susceptibility To Mental Illnesses

    Nithianantharajah, J., McKechanie, A., Komiyama, N., Emes, R. D., Saksida, L. M., Bussey, T. J. & Grant, S., 18 Jul 2012, p. 641

    Research output: Contribution to conferencePoster

  61. SynGAP isoforms exert opposing effects on synaptic strength

    McMahon, A. C., Barnett, M. W., O'Leary, T. S., Stoney, P. N., Collins, M. O., Papadia, S., Choudhary, J. S., Komiyama, N. H., Grant, S. G. N., Hardingham, G. E., Wyllie, D. J. A. & Kind, P. C., Jun 2012, In : Nature Communications. 3, 9 p., 900

    Research output: Contribution to journalArticle

  62. The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

    Martel, M-A., Ryan, T. J., Bell, K. F. S., Fowler, J. H., McMahon, A., Al-Mubarak, B., Komiyama, N., Horsburgh, K., Kind, P. C., Grant, S. G. N., Wyllie, D. J. A. & Hardingham, G. E., May 2012, In : Neuron. 74, 3, p. 543-556 14 p.

    Research output: Contribution to journalArticle

  63. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

    Kirov, G., Pocklington, A. J., Holmans, P., Ivanov, D., Ikeda, M., Ruderfer, D., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., Grozeva, D., Fjodorova, M., Wollerton, R., Rees, E., Nikolov, I., Van De Lagemaat, L., Bayés, A., Fernandez, E., Olason, P. I., Böttcher, Y. & 10 othersKomiyama, N. H., Collins, M. O., Choudhary, J., Stefansson, K., Stefansson, H., Grant, S. G. N., Purcell, S., Sklar, P., O'Donovan, M. C. & Owen, M. J., Feb 2012, In : Molecular Psychiatry. 17, 2, p. 142-153 12 p.

    Research output: Contribution to journalArticle

  64. An anatomically comprehensive atlas of the adult human brain transcriptome

    Hawrylycz, M. J., Lein, E. S., Guillozet-Bongaarts, A. L., Shen, E. H., Ng, L., Miller, J. A., Van De Lagemaat, L., Smith, K. A., Ebbert, A., Riley, Z. L., Abajian, C., Beckmann, C. F., Bernard, A., Bertagnolli, D., Boe, A. F., Cartagena, P. M., Chakravarty, M. M., Chapin, M., Chong, J., Dalley, R. A. & 47 othersDaly, B. D., Dang, C., Datta, S., Dee, N., Dolbeare, T. A., Faber, V., Feng, D., Fowler, D. R., Goldy, J., Gregor, B. W., Haradon, Z., Haynor, D. R., Hohmann, J. G., Horvath, S., Howard, R. E., Jeromin, A., Jochim, J. M., Kinnunen, M., Lau, C., Lazarz, E. T., Lee, C., Lemon, T. A., Li, L., Li, Y., Morris, J. A., Overly, C. C., Parker, P. D., Parry, S. E., Reding, M., Royall, J. J., Schulkin, J., Sequeira, P. A., Slaughterbeck, C. R., Smith, S. C., Sodt, A. J., Sunkin, S. M., Swanson, B. E., Vawter, M. P., Williams, D., Wohnoutka, P., Zielke, H. R., Geschwind, D. H., Hof, P. R., Smith, S. M., Koch, C., Grant, S. G. N. & Jones, A. R., 2012, In : Nature. 489, 7416, p. 391-399 9 p.

    Research output: Contribution to journalArticle

  65. Evolution of Synapse Complexity and Diversity

    Emes, R. D. & Grant, S. G. N., 2012, ANNUAL REVIEW OF NEUROSCIENCE, VOL 35. Hyman, SE. (ed.). PALO ALTO: ANNUAL REVIEWS, p. 111-131 21 p. (Annual Review of Neuroscience; vol. 35)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  66. Synaptopathies: diseases of the synaptome

    Grant, S. G., 2012, In : Current Opinion in Neurobiology.

    Research output: Contribution to journalArticle

  67. 2011
  68. Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

    Van Campenhout, C. A., Eitelhuber, A., Gloeckner, C. J., Giallonardo, P., Gegg, M., Oller, H., Grant, S. G. N., Krappmann, D., Ueffing, M. & Lickert, H., 13 Sep 2011, In : Developmental Cell. 21, 3, p. 479-491 13 p.

    Research output: Contribution to journalArticle

  69. Beta-adrenergic receptor activation rescues theta frequency stimulation-induced LTP deficits in mice expressing C-terminally truncated NMDA receptor GluN2A subunits

    Moody, T. D., Watabe, A. M., Indersmitten, T., Komiyama, N. H., Grant, S. G. N. & O'Dell, T. J., Feb 2011, In : Learning and Memory. 18, 2, p. 118-27 10 p.

    Research output: Contribution to journalArticle

  70. Characterization of the proteome, diseases and evolution of the human postsynaptic density

    Bayes, A., Van De Lagemaat, L., Collins, M. O., Croning, M. D. R., Whittle, I. R., Choudhary, J. S. & Grant, S. G. N., Jan 2011, In : Nature Neuroscience. 14, 1, p. 19-21 3 p.

    Research output: Contribution to journalArticle

  71. 2010
  72. Association of Mouse Dlg4 (PSD-95) Gene Deletion and Human DLG4 Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams' Syndrome

    Feyder, M., Karlsson, R-M., Mathur, P., Lyman, M., Bock, R., Momenan, R., Munasinghe, J., Scattoni, M. L., Ihne, J., Camp, M., Graybeal, C., Strathdee, D., Begg, A., Alvarez, V. A., Kirsch, P., Rietschel, M., Cichon, S., Walter, H., Meyer-Lindenberg, A., Grant, S. G. N. & 1 othersHolmes, A., Dec 2010, In : American Journal of Psychiatry. 167, 12, p. 1508-1517 10 p.

    Research output: Contribution to journalArticle

  73. Thigh-Length Versus Below-Knee Stockings for Deep Venous Thrombosis Prophylaxis After Stroke: A Randomized Trial

    Dennis, M., Cranswick, G., Deary, A., Fraser, A., Graham, C., Grant, S., Gunkel, A., Hunter, J., MacRae, A., Perry, D., Soosay, V., Williams, C., Williamson, A., Young, A., Sandercock, P., Reid, J., Murray, G., Venables, G., Rudd, A., Bowler, G. & 10 othersCelani, M. G., Ricci, S., Lindley, R., Hautvast, M., Paterson, M., Ting, T., Baigent, C., Bamford, J., Slattery, J. & CLOTS Trial Collaborat, 2 Nov 2010, In : Annals of Internal Medicine. 153, 9, p. 553-562 10 p.

    Research output: Contribution to journalArticle

  74. Genome variation and complexity in the autism spectrum

    van de Lagemaat, L. N. & Grant, S. G. N., 15 Jul 2010, In : Neuron. 67, 1, p. 8-10 3 p.

    Research output: Contribution to journalArticle

  75. In Vivo Composition of NMDA Receptor Signaling Complexes Differs between Membrane Subdomains and Is Modulated by PSD-95 And PSD-93

    Delint-Ramirez, I., Fernandez, E., Bayes, A., Kicsi, E., Komiyama, N. & Grant, S. G. N., 16 Jun 2010, In : The Journal of Neuroscience. 30, 24, p. 8162-8170 9 p.

    Research output: Contribution to journalArticle

  76. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment

    Arbuckle, M. I., Komiyama, N. H., Delaney, A., Coba, M., Garry, E. M., Rosie, R., Allchorne, A. J., Forsyth, L. H., Bence, M., Carlisle, H. J., O'Dell, T. J., Mitchell, R., Fleetwood-Walker, S. M. & Grant, S., Jun 2010, In : EMBO Reports. 11, 6, p. 473-478 6 p.

    Research output: Contribution to journalArticle

  77. Automated design of genomic Southern blot probes

    Croning, M. D. R., Fricker, D. G., Komiyama, N. H. & Grant, S. G. N., 2010, In : BMC Genomics. 11, p. 74

    Research output: Contribution to journalArticle

  78. 2009
  79. INTEGRINS CONTRIBUTE TO THE AXOGLIAL INTERACTIONS THAT INITIATE MYELINATION IN THE CNS

    Nunes-Fonseca, C., Camara, J., Wang, Z., Friedman, H. C., Grove, M., Sherman, D. L., Komiyama, N. H., Grant, S. G., Brophy, P. J., Peterson, A. & Ffrench-Constant, C., Oct 2009, In : Glia. 57, 13, p. S42-S42 1 p.

    Research output: Contribution to journalMeeting abstract

  80. PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors

    Abbas, A. I., Yadav, P. N., Yao, W-D., Arbuckle, M. I., Grant, S. G. N., Caron, M. G. & Roth, B. L., 3 Jun 2009, In : Journal of Neuroscience. 29, 22, p. 7124-7136 13 p.

    Research output: Contribution to journalArticle

  81. Integrin-mediated axoglial interactions initiate myelination in the central nervous system

    Câmara, J., Wang, Z., Nunes-Fonseca, C., Friedman, H. C., Grove, M., Sherman, D. L., Komiyama, N. H., Grant, S. G., Brophy, P. J., Peterson, A. & ffrench-Constant, C., May 2009, In : The Journal of Cell Biology. 185, 4, p. 699-712 14 p.

    Research output: Contribution to journalArticle

  82. Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins

    Fernandez, E., Collins, M. O., Uren, R. T., Kopanitsa, M. V., Komiyama, N. H., Croning, M. D. R., Zografos, L., Armstrong, J. D., Choudhary, J. S. & Grant, S. G. N., May 2009, In : Molecular Systems Biology. 5, p. - 17 p., 269

    Research output: Contribution to journalArticle

  83. Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks

    Coba, M. P., Pocklington, A. J., Collins, M. O., Kopanitsa, M. V., Uren, R. T., Swamy, S., Croning, M. D. R., Choudhary, J. S. & Grant, S. G. N., Apr 2009, In : Science Signaling. 2, 68, ra19

    Research output: Contribution to journalArticle

  84. G2Cdb: the Genes to Cognition database

    Croning, M. D. R., Marshall, M. C., McLaren, P., Armstrong, J. D. & Grant, S. G. N., Jan 2009, In : Nucleic Acids Research. 37, p. D846-D851 6 p.

    Research output: Contribution to journalArticle

  85. Evolution of the synapse proteome

    Armstrong, J. D., Malik, B., Pocklington, A., Emes, R. & Grant, S., 2009, In : Journal of neurogenetics. 23, p. S34-S35 2 p.

    Research output: Contribution to journalMeeting abstract

  86. 2008
  87. Evolutionary expansion and anatomical specialization of synapse proteome complexity

    Emes, R. D., Pocklington, A. J., Anderson, C. N. G., Bayes, A., Collins, M. O., Vickers, C. A., Croning, M. D. R., Malik, B. R., Choudhary, J. S., Armstrong, D. & Grant, S., Jul 2008, In : Nature Neuroscience. 11, 7, p. 799-806 8 p.

    Research output: Contribution to journalArticle

  88. Objective measurement of physical activity and sedentary behaviour: review with new data

    Reilly, J. J., Penpraze, V., Hislop, J., Davies, G., Grant, S. & Paton, J. Y., Jul 2008, In : Archives of Disease in Childhood. 93, 7, p. 614-619 6 p.

    Research output: Contribution to journalLiterature review

  89. Evolution of NMDA receptor cytoplasmic interaction domains: implications for organisation of synaptic signalling complexes

    Ryan, T. J., Emes, R. D., Grant, S. G. & Komiyama, N. H., 2008, In : BMC Neuroscience. 9, p. 6

    Research output: Contribution to journalArticle

  90. 2007
  91. Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies

    Cuthbert, P. C., Stanford, L. E., Coba, M. P., Ainge, J. A., Fink, A. E., Opazo, P., Delgado, J. Y., Komiyama, N. H., O'Dell, T. J. & Grant, S. G. N., 7 Mar 2007, In : Journal of Neuroscience. 27, 10, p. 2673-82 10 p.

    Research output: Contribution to journalArticle

  92. FAK is required for axonal sorting by Schwann cells

    Grove, M., Komiyama, N. H., Nave, K-A., Grant, S. G., Sherman, D. L. & Brophy, P. J., 2007, In : The Journal of Cell Biology. 176, 3, p. 277-82 6 p.

    Research output: Contribution to journalArticle

  93. 2006
  94. The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour

    Pocklington, A. J., Cumiskey, M., Armstrong, J. D. & Grant, S. G. N., 17 Jan 2006, In : Molecular Systems Biology. 2, 14 p., 2006.0023

    Research output: Contribution to journalArticle

  95. Organization of brain complexity--synapse proteome form and function

    Pocklington, A. J., Armstrong, J. D. & Grant, S. G. N., 2006, In : Briefings in functional genomics & proteomics. 5, 1, p. 66-73 8 p.

    Research output: Contribution to journalArticle

  96. Reconstructing protein complexes: From proteomics to systems biology

    Armstrong, J. D., Pocklington, A. J., Cumiskey, M. A. & Grant, S. G. N., 2006, In : Proteomics. 6, 17, p. 4724-4731 8 p.

    Research output: Contribution to journalArticle

  97. Synaptic Ras GTPase activating protein regulates pattern formation in the trigeminal system of mice

    Barnett, M. W., Watson, R. F., Vitalis, T., Porter, K., Komiyama, N. H., Stoney, P. N., Gillingwater, T. H., Grant, S. G. N. & Kind, P. C., 2006, In : Journal of Neuroscience. 26, 5, p. 1355-65 11 p.

    Research output: Contribution to journalArticle

  98. 2005
  99. Synapse proteomics of multiprotein complexes: en route from genes to nervous system diseases

    Grant, S. G. N., Marshall, M. C., Page, K-L., Cumiskey, M. A. & Armstrong, J. D., 2005, In : Human Molecular Genetics. 14, suppl 2, p. R225-R234 10 p.

    Research output: Contribution to journalArticle

  100. 2004
  101. Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression

    McLean, G. W., Komiyama, N. H., Serrels, B., Asano, H., Reynolds, L., Conti, F., Hodivala-Dilke, K., Metzger, D., Chambon, P., Grant, S. G. N. & Frame, M. C., 15 Dec 2004, In : Genes & Development. 18, 24, p. 2998-3003 6 p.

    Research output: Contribution to journalArticle

  102. The Organization and integrative function of the post-synaptic proteome

    Grant, S., Husi, H., Choudhary, J., Cumiskey, M., Blackstock, W. & Armstrong, D., 2004, Excitatory-Inhibitory Balance: Synapses, Circuits, Systems. KLUWER ACADEMIC/PLENUM PUBL, p. 13-44 32 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

  103. 2003
  104. Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling

    Fagiolini, M., Katagiri, H., Miyamoto, H., Mori, H., Grant, S. G. N., Mishina, M. & Hensch, T. K., 4 Mar 2003, In : Proceedings of the National Academy of Sciences. 100, 5, p. 2854-9 6 p.

    Research output: Contribution to journalArticle

  105. 2002
  106. SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor

    Komiyama, N. H., Watabe, A. M., Carlisle, H. J., Porter, K., Charlesworth, P., Monti, J., Strathdee, D. J. C., O'Carroll, C. M., Martin, S. J., Morris, R. G. M., O'Dell, T. J. & Grant, S. G. N., 15 Nov 2002, In : Journal of Neuroscience. 22, 22, p. 9721-32 12 p.

    Research output: Contribution to journalArticle

  107. 1997
  108. Mutant mice and neuroscience: Recommendations concerning genetic background

    Silva, A. J., Simpson, E. M., Takahashi, J. S., Lipp, H. P., Nakanishi, S., Wehner, J. M., Giese, K. P., Tully, T., Abel, T., Chapman, P. F., Fox, K., Grant, S., Itohara, S., Lathe, R., Mayford, M., McNamara, J. O., Morris, R. J., Picciotto, M., Roder, J., Shin, H. S. & 6 othersSlesinger, P. A., Storm, D. R., Stryker, M. P., Tonegawa, S., Wang, Y. & Wolfer, D. P., 1997, In : Neuron. 19, 4, p. 755-759 5 p.

    Research output: Contribution to journalComment/debate

  109. 1990
  110. Efficient linkage of 10 loci in the proximal region of the mouse X chromosome

    Mullins, L. J., Stephenson, D. A., Grant, S. G. & Chapman, V. M., May 1990, In : Genomics. 7, 1, p. 19-30 12 p.

    Research output: Contribution to journalArticle

  111. 1988
  112. Multilocus molecular mapping of the mouse X chromosome

    Mullins, L. J., Grant, S. G., Stephenson, D. A. & Chapman, V. M., Oct 1988, In : Genomics. 3, 3, p. 187-94 8 p.

    Research output: Contribution to journalArticle

  113. X-chromosome gene order in different Mus species crosses

    Stephenson, D. A., Grant, S. G., Mullins, L. J., Scolese, A. E., O'Reilly, A. J. & Chapman, V. M., 1988, In : Current topics in microbiology and immunology. 137, p. 18-24 7 p.

    Research output: Contribution to journalArticle

  114. 1987
  115. Regional localization of the murine Duchenne muscular dystrophy gene on the mouse X chromosome

    Chamberlain, J. S., Grant, S. G., Reeves, A. A., Mullins, L. J., Stephenson, D. A., Hoffman, E. P., Monaco, A. P., Kunkel, L. M., Caskey, C. T. & Chapman, V. M., Nov 1987, In : Somatic Cell and Molecular Genetics. 13, 6, p. 671-8 8 p.

    Research output: Contribution to journalArticle