Edinburgh Research Explorer

Prof Seth Grant

Personal Chair of Molecular Neuroscience

  1. 2019
  2. Cell‐type specific visualization and biochemical isolation of endogenous synaptic proteins in mice

    Zhu, F., Collins, M. O., Harmse, J., Choudhary, J. S., Grant, S. G. N. & Komiyama, N. H., 16 Oct 2019, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  3. NMDA receptor modulation of glutamate release in activated neutrophils

    Del Arroyo, A. G., Hadjihambi, A., Sanchez, J., Turovsky, E., Kasymov, V., Cain, D., Nightingale, T. D., Lambden, S., Grant, S. G. N., Gourine, A. V. & Ackland, G. L., 8 Aug 2019, In : EBioMedicine.

    Research output: Contribution to journalArticle

  4. Synapse diversity and synaptome architecture in human genetic disorders

    Grant, S. G. N., 26 Jul 2019, In : Human Molecular Genetics.

    Research output: Contribution to journalReview article

  5. Comprehensive behavioral analysis of heterozygous Syngap1knockout mice

    Nakajima, R., Takao, K., Hattori, S., Shoji, H., Komiyama, N. H., Grant, S. G. N. & Miyakawa, T., 19 Jul 2019, In : Neuropsychopharmacology Reports.

    Research output: Contribution to journalArticle

  6. Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, A., Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, H., Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, K., 15 May 2019, In : Neuropharmacology. 150

    Research output: Contribution to journalArticle

  7. Computational geometry analysis of dendritic spines by structured illumination microscopy

    Kashiwagi, Y., Higashi, T., Obashi, K., Sato, Y., Komiyama, N. H., Grant, S. G. N. & Okabe, S., 20 Mar 2019, In : Nature Communications. 10, 1

    Research output: Contribution to journalArticle

  8. The Synaptomic Theory of Behavior and Brain Disease

    Grant, S. G. N., 18 Mar 2019, In : Cold Spring Harbor Symposia on Quantitative Biology. p. 037887

    Research output: Contribution to journalArticle

  9. 2018
  10. Synapse molecular complexity and the plasticity-behaviour problem

    Grant, S., 15 Nov 2018, In : Brain and Neuroscience Advances.

    Research output: Contribution to journalArticle

  11. Rapid homeostatic downregulation of LTP by extrasynaptic GluN2B receptors

    Delgado, J. Y., Fink, A. E., Grant, S. G. N., O'Dell, T. J. & Opazo, P., Nov 2018, In : Journal of Neurophysiology.

    Research output: Contribution to journalArticle

  12. Architecture of the Mouse Brain Synaptome

    Zhu, F., Cizeron, M., Qiu, Z., Benavides-piccione, R., Kopanitsa, M. V., Skene, N. G., Koniaris, B., Defelipe, J., Fransén, E., Komiyama, N. H. & Grant, S. G. N., 2 Aug 2018, In : Neuron.

    Research output: Contribution to journalArticle

  13. Regional Diversity in the Postsynaptic Proteome of the Mouse Brain

    Roy, M., Sorokina, O., McLean, C., Tapia-González, S., DeFelipe, J., Armstrong, J. D. & Grant, S., 1 Aug 2018, In : Proteomes. 6, 3, 18 p.

    Research output: Contribution to journalArticle

  14. Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1 mice

    Kopanitsa, M. V., Gou, G., Afinowi, N. O., Bayés, À., Grant, S. G. N. & Komiyama, N. H., Aug 2018, In : Pharmacological reports. 70, 4, p. 777-783 7 p.

    Research output: Contribution to journalArticle

  15. Dlgap1 knockout mice exhibit alterations of the postsynaptic density and selective reductions in sociability

    Coba, M. P., Ramaker, M. J., Ho, E. V., Thompson, S. L., Komiyama, N. H., Grant, S. G. N., Knowles, J. A. & Dulawa, S. C., 2 Feb 2018, In : Scientific Reports. 8, 1

    Research output: Contribution to journalArticle

  16. In vivo STED microscopy visualizes morphological changes of large PSD95 assemblies over several hours in the mouse visual cortex

    Wegner, W., Mott, A. C., Grant, S., Steffens, H. & Willig, K. I., 9 Jan 2018, In : Scientific Reports.

    Research output: Contribution to journalArticle

  17. 2017
  18. Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95

    Horner, A. E., McLaughlin, C. L., Afinowi, N. O., Bussey, T. J., Saksida, L. M., Komiyama, N. H., Grant, S. G. N. & Kopanitsa, M. V., 13 Dec 2017, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  19. Proteomic analysis of postsynaptic proteins in regions of the human neocortex

    Roy, M., Sorokina, O., Skene, N., Simonnet, C., Mazzola, F., Zwart, R., Sher, E., Smith, C., Armstrong, J. D. & Grant, S., 4 Dec 2017, In : Nature Neuroscience.

    Research output: Contribution to journalArticle

  20. Arc requires PSD95 for assembly into postsynaptic complexes involved with brain disease and intelligence

    Fernandez, E., Collins, M. O., Frank, R. A. W., Zhu, F., Kopanitsa, M. V., Nithianantharajah, J., Lempriere, S., Fricker, D. G., Elsegood, K. A., McLaughlin, C., Croning, M. D. R., McLean, C., Armstrong, J. D., Hill, W. D., Deary, I., Cencelli, G., Bagni, C., Fromer, M., Purcell, S. M., Pocklington, A. J. & 3 others, Choudhary, J. S., Komiyama, N. & Grant, S., 17 Oct 2017, In : Cell Reports. 21, 3, p. 679-691

    Research output: Contribution to journalArticle

  21. A genomic lifespan program that reorganises the young adult brain is targeted in schizophrenia

    Skene, N. G., Roy, M. & Grant, S. G., 12 Sep 2017, In : eLIFE. 6

    Research output: Contribution to journalArticle

  22. Supramolecular organization of NMDA receptors and the postsynaptic density

    Frank, R. A. & Grant, S. G., Aug 2017, In : Current Opinion in Neurobiology. 45, p. 139-147 9 p.

    Research output: Contribution to journalArticle

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