Edinburgh Research Explorer

Prof Seth Grant

Personal Chair of Molecular Neuroscience

  1. 2012
  2. Genetic Dissection Of Cognition In Humans And Mice Carrying Mutations: Evidence That Vertebrate Genomic Evolution Produced Susceptibility To Mental Illnesses

    Nithianantharajah, J., McKechanie, A., Komiyama, N., Emes, R. D., Saksida, L. M., Bussey, T. J. & Grant, S., 18 Jul 2012, p. 641.

    Research output: Contribution to conferencePoster

  3. SynGAP isoforms exert opposing effects on synaptic strength

    McMahon, A. C., Barnett, M. W., O'Leary, T. S., Stoney, P. N., Collins, M. O., Papadia, S., Choudhary, J. S., Komiyama, N. H., Grant, S. G. N., Hardingham, G. E., Wyllie, D. J. A. & Kind, P. C., Jun 2012, In : Nature Communications. 3, 9 p., 900.

    Research output: Contribution to journalArticle

  4. The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

    Martel, M-A., Ryan, T. J., Bell, K. F. S., Fowler, J. H., McMahon, A., Al-Mubarak, B., Komiyama, N., Horsburgh, K., Kind, P. C., Grant, S. G. N., Wyllie, D. J. A. & Hardingham, G. E., May 2012, In : Neuron. 74, 3, p. 543-556 14 p.

    Research output: Contribution to journalArticle

  5. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

    Kirov, G., Pocklington, A. J., Holmans, P., Ivanov, D., Ikeda, M., Ruderfer, D., Moran, J., Chambert, K., Toncheva, D., Georgieva, L., Grozeva, D., Fjodorova, M., Wollerton, R., Rees, E., Nikolov, I., Van De Lagemaat, L., Bayés, A., Fernandez, E., Olason, P. I., Böttcher, Y. & 10 others, Komiyama, N. H., Collins, M. O., Choudhary, J., Stefansson, K., Stefansson, H., Grant, S. G. N., Purcell, S., Sklar, P., O'Donovan, M. C. & Owen, M. J., Feb 2012, In : Molecular Psychiatry. 17, 2, p. 142-153 12 p.

    Research output: Contribution to journalArticle

  6. An anatomically comprehensive atlas of the adult human brain transcriptome

    Hawrylycz, M. J., Lein, E. S., Guillozet-Bongaarts, A. L., Shen, E. H., Ng, L., Miller, J. A., Van De Lagemaat, L., Smith, K. A., Ebbert, A., Riley, Z. L., Abajian, C., Beckmann, C. F., Bernard, A., Bertagnolli, D., Boe, A. F., Cartagena, P. M., Chakravarty, M. M., Chapin, M., Chong, J., Dalley, R. A. & 47 others, Daly, B. D., Dang, C., Datta, S., Dee, N., Dolbeare, T. A., Faber, V., Feng, D., Fowler, D. R., Goldy, J., Gregor, B. W., Haradon, Z., Haynor, D. R., Hohmann, J. G., Horvath, S., Howard, R. E., Jeromin, A., Jochim, J. M., Kinnunen, M., Lau, C., Lazarz, E. T., Lee, C., Lemon, T. A., Li, L., Li, Y., Morris, J. A., Overly, C. C., Parker, P. D., Parry, S. E., Reding, M., Royall, J. J., Schulkin, J., Sequeira, P. A., Slaughterbeck, C. R., Smith, S. C., Sodt, A. J., Sunkin, S. M., Swanson, B. E., Vawter, M. P., Williams, D., Wohnoutka, P., Zielke, H. R., Geschwind, D. H., Hof, P. R., Smith, S. M., Koch, C., Grant, S. G. N. & Jones, A. R., 2012, In : Nature. 489, 7416, p. 391-399 9 p.

    Research output: Contribution to journalArticle

  7. Evolution of Synapse Complexity and Diversity

    Emes, R. D. & Grant, S. G. N., 2012, ANNUAL REVIEW OF NEUROSCIENCE, VOL 35. Hyman, SE. (ed.). PALO ALTO: ANNUAL REVIEWS, p. 111-131 21 p. (Annual Review of Neuroscience; vol. 35).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  8. Synaptopathies: diseases of the synaptome

    Grant, S. G., 2012, In : Current Opinion in Neurobiology.

    Research output: Contribution to journalArticle

  9. 2011
  10. Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

    Van Campenhout, C. A., Eitelhuber, A., Gloeckner, C. J., Giallonardo, P., Gegg, M., Oller, H., Grant, S. G. N., Krappmann, D., Ueffing, M. & Lickert, H., 13 Sep 2011, In : Developmental Cell. 21, 3, p. 479-491 13 p.

    Research output: Contribution to journalArticle

  11. Beta-adrenergic receptor activation rescues theta frequency stimulation-induced LTP deficits in mice expressing C-terminally truncated NMDA receptor GluN2A subunits

    Moody, T. D., Watabe, A. M., Indersmitten, T., Komiyama, N. H., Grant, S. G. N. & O'Dell, T. J., Feb 2011, In : Learning & Memory. 18, 2, p. 118-27 10 p.

    Research output: Contribution to journalArticle

  12. Characterization of the proteome, diseases and evolution of the human postsynaptic density

    Bayes, A., Van De Lagemaat, L., Collins, M. O., Croning, M. D. R., Whittle, I. R., Choudhary, J. S. & Grant, S. G. N., Jan 2011, In : Nature Neuroscience. 14, 1, p. 19-21 3 p.

    Research output: Contribution to journalArticle

  13. 2010
  14. Association of Mouse Dlg4 (PSD-95) Gene Deletion and Human DLG4 Gene Variation With Phenotypes Relevant to Autism Spectrum Disorders and Williams' Syndrome

    Feyder, M., Karlsson, R-M., Mathur, P., Lyman, M., Bock, R., Momenan, R., Munasinghe, J., Scattoni, M. L., Ihne, J., Camp, M., Graybeal, C., Strathdee, D., Begg, A., Alvarez, V. A., Kirsch, P., Rietschel, M., Cichon, S., Walter, H., Meyer-Lindenberg, A., Grant, S. G. N. & 1 others, Holmes, A., Dec 2010, In : American Journal of Psychiatry. 167, 12, p. 1508-1517 10 p.

    Research output: Contribution to journalArticle

  15. Thigh-Length Versus Below-Knee Stockings for Deep Venous Thrombosis Prophylaxis After Stroke: A Randomized Trial

    Dennis, M., Cranswick, G., Deary, A., Fraser, A., Graham, C., Grant, S., Gunkel, A., Hunter, J., MacRae, A., Perry, D., Soosay, V., Williams, C., Williamson, A., Young, A., Sandercock, P., Reid, J., Murray, G., Venables, G., Rudd, A., Bowler, G. & 10 others, Celani, M. G., Ricci, S., Lindley, R., Hautvast, M., Paterson, M., Ting, T., Baigent, C., Bamford, J., Slattery, J. & CLOTS Trial Collaborat, 2 Nov 2010, In : Annals of Internal Medicine. 153, 9, p. 553-562 10 p.

    Research output: Contribution to journalArticle

  16. Genome variation and complexity in the autism spectrum

    van de Lagemaat, L. N. & Grant, S. G. N., 15 Jul 2010, In : Neuron. 67, 1, p. 8-10 3 p.

    Research output: Contribution to journalArticle

  17. In Vivo Composition of NMDA Receptor Signaling Complexes Differs between Membrane Subdomains and Is Modulated by PSD-95 And PSD-93

    Delint-Ramirez, I., Fernandez, E., Bayes, A., Kicsi, E., Komiyama, N. & Grant, S. G. N., 16 Jun 2010, In : The Journal of Neuroscience. 30, 24, p. 8162-8170 9 p.

    Research output: Contribution to journalArticle

  18. The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment

    Arbuckle, M. I., Komiyama, N. H., Delaney, A., Coba, M., Garry, E. M., Rosie, R., Allchorne, A. J., Forsyth, L. H., Bence, M., Carlisle, H. J., O'Dell, T. J., Mitchell, R., Fleetwood-Walker, S. M. & Grant, S., Jun 2010, In : EMBO Reports. 11, 6, p. 473-478 6 p.

    Research output: Contribution to journalArticle

  19. Automated design of genomic Southern blot probes

    Croning, M. D. R., Fricker, D. G., Komiyama, N. H. & Grant, S. G. N., 2010, In : BMC Genomics. 11, p. 74

    Research output: Contribution to journalArticle

  20. 2009
  21. INTEGRINS CONTRIBUTE TO THE AXOGLIAL INTERACTIONS THAT INITIATE MYELINATION IN THE CNS

    Nunes-Fonseca, C., Camara, J., Wang, Z., Friedman, H. C., Grove, M., Sherman, D. L., Komiyama, N. H., Grant, S. G., Brophy, P. J., Peterson, A. & Ffrench-Constant, C., Oct 2009, In : Glia. 57, 13, p. S42-S42 1 p.

    Research output: Contribution to journalMeeting abstract

  22. PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors

    Abbas, A. I., Yadav, P. N., Yao, W-D., Arbuckle, M. I., Grant, S. G. N., Caron, M. G. & Roth, B. L., 3 Jun 2009, In : Journal of Neuroscience. 29, 22, p. 7124-7136 13 p.

    Research output: Contribution to journalArticle

  23. Integrin-mediated axoglial interactions initiate myelination in the central nervous system

    Câmara, J., Wang, Z., Nunes-Fonseca, C., Friedman, H. C., Grove, M., Sherman, D. L., Komiyama, N. H., Grant, S. G., Brophy, P. J., Peterson, A. & ffrench-Constant, C., May 2009, In : Journal of Cell Biology. 185, 4, p. 699-712 14 p.

    Research output: Contribution to journalArticle