Edinburgh Research Explorer

Prof Shareen Forbes

Personal Chair of Diabetic Medicine

  1. 2018
  2. Short term glucose dysregulation following acute poisoning with organophosphorus insecticides but not herbicides, carbamate or pyrethroid insecticides in South Asia

    Gifford, R., Chathuranga, U., Lamb, T., Verma, V. R., Sattar, M. A., Thompson, A., Siribaddana, S., Ghose, A., Forbes, S., Reynolds, R. & Eddleston, M., 11 Oct 2018, In : Clinical Toxicology.

    Research output: Contribution to journalArticle

  3. Comparison of Metabolic Responses To The Mixed Meal Tolerance Test Versus The Oral Glucose Tolerance Test After Successful Clinical Islet Transplantation

    Forbes, S., Lam, A., Koh, A., Imes, S., Dinyari, P., Malcolm, A. J., Shapiro, A. J. & Senior, P. A., 22 Jun 2018, In : Clinical transplantation. p. e13301

    Research output: Contribution to journalArticle

  4. Islet transplantation in type 1 diabetes: moving forward

    Forbes, S., Senior, P. A. & Shapiro, A. M. J., 15 May 2018, In : The Lancet Diabetes and Endocrinology.

    Research output: Contribution to journalComment/debate

  5. 2017
  6. Maternal lipids in pregnancy are associated with increased offspring cortisol reactivity in childhood

    Mina, T. H., Lahti, M., Drake, A., Forbes, S., Denison, F., Räikkönen, K., Norman, J. & Reynolds, R., Sep 2017, In : Psychoneuroendocrinology. 83, p. 79-83

    Research output: Contribution to journalArticle

  7. Functionalized superparamagnetic iron oxide nanoparticles provide highly efficient iron-labelling in macrophages for magnetic resonance-based detection in vivo

    Sharkey, J., Starkey Lewis, P. J., Barrow, M., Alwahsh, S., Noble, J., Livingstone, E., Lennen, R. J., Jansen, M. A., Carrion, J. G., Liptrott, N., Adams, D. J., Chadwick, A. E., Forbes, S. J., Murray, P., Rosseinsky, M. J., Goldring, C. E., Park, B. K. & Forbes, S., Apr 2017, In : Cytotherapy. 19, 4, p. 555-569

    Research output: Contribution to journalArticle

  8. Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism

    Thompson, A. A. R., Dickinson, R., Murphy, F., Thomson, J. P., Marriott, H. M., Tavares, A., Willson, J. A., Williams, L., Lewis, A., Mirchandani Thanwerdas, A., Dos Santos Coelho, P., Doherty, C., Ryan, E., Watts, E., Morton, N., Stimson, R., Hameed, A. G., Arnold, N., Preston, J. A., Lawrie, A. & 15 others, Finisguerra, V., Mazzone, M., Sadiku, P., Goveia, J., Taverna, F., Carmeliet, P., Foster, S. J., Chilvers, E. R., Cowburn, A. S., Dockrell, D. H., Johnson, R. S., Meehan, R., Whyte, M., Walmsley, S. & Forbes, S., 10 Feb 2017, In : Science Immunology. 2, 8, eaal2861.

    Research output: Contribution to journalArticle

  9. Insulin Production and Resistance in Different Models of Diet-Induced Obesity and Metabolic Syndrome

    Alwahsh, S., Dwyer, B., Forbes, S., Van Thiel, D. H., Starkey Lewis, P. & Ramadori, G., 28 Jan 2017, In : International Journal of Molecular Sciences. 18, 2, E285.

    Research output: Contribution to journalArticle

  10. 2016
  11. Validation of the BETA-2 Score: An Improved Tool to Estimate Beta Cell Function After Clinical Islet Transplantation Using a Single Fasting Blood Sample

    Forbes, S., Oram, R. A., Smith, A., Lam, A., Olateju, T., Imes, S., Malcolm, A. J., Shapiro, A. M. J. & Senior, P. A., Sep 2016, In : American Journal of Transplantation. 16, 9

    Research output: Contribution to journalArticle

  12. Does metformin reduce excess birthweight in offspring of obese pregnant women? A randomised controlled trial of efficacy, exploration of mechanisms and evaluation of other pregnancy complications

    Chiswick, C., Reynolds, R., Denison, F., Drake, A., Forbes, S., Newby, D., Walker, B., Quenby, S., Wray, S., Weeks, A., Lashen, H., Murray, G., Whyte, S., Andrew, R., Homer, N., Semple, S., Gray, C., Aldhous, M., Noble, K., Cunningham-Burley, S. & 1 others, Norman, J., 31 Aug 2016, In : Efficacy and Mechanism Evaluation. 3, 7

    Research output: Contribution to journalArticle

  13. Generation of Functional Beta-Like Cells from Human Exocrine Pancreas

    Lima, M. J., Muir, K. R., Docherty, H. M., McGowan, N. W. A., Forbes, S., Heremans, Y., Heimberg, H., Casey, J. & Docherty, K., 31 May 2016, In : PLoS ONE. 11, 5, p. e0156204

    Research output: Contribution to journalArticle

  14. 2015
  15. Endocrine-disrupting chemicals and the diabetes epidemic in countries in the WHO South-East Asia region

    Gifford, R., Siribaddana, S., Forbes, S. & Eddleston, M., Dec 2015, In : The Lancet Diabetes and Endocrinology. 3, 12, p. 925-7 3 p.

    Research output: Contribution to journalComment/debate

  16. Krüppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture

    Muir, K. R., Lima, M. J., Docherty, H. M., Mcgowan, N. W. A., Forbes, S., Heremans, Y., Forbes, S. J., Heimberg, H., Casey, J. & Docherty, K., 12 Oct 2015, In : PLoS ONE. 10, 10, p. e0140352

    Research output: Contribution to journalArticle

  17. Health Behaviours during Pregnancy in Women with Very Severe Obesity

    Mohd-Shukri, N. A., Duncan, A., Denison, F. C., Forbes, S., Walker, B. R., Norman, J. E. & Reynolds, R. M., 7 Oct 2015, In : Nutrients. 7, 10, p. 8431-43 13 p.

    Research output: Contribution to journalArticle

  18. Effect of metformin on maternal and fetal outcomes in obese pregnant women (EMPOWaR): a randomised, double-blind, placebo-controlled trial

    Chiswick, C., Reynolds, R., Denison, F., Drake, A., Forbes, S., Newby, D., Walker, B., Quenby, S., Wray, S., Weeks, A., Lashen, H., Rodriguez Carbonell, A., Murray, G., Whyte, S. & Norman, J., Oct 2015, In : The Lancet Diabetes and Endocrinology.

    Research output: Contribution to journalArticle

  19. Decreased maternal hypothalamic-pituitary-adrenal axis activity in very severely obese pregnancy: Associations with birthweight and gestation at delivery

    Stirrat, L. I., O'Reilly, J. R., Barr, S. M., Andrew, R., Riley, S. C., Howie, A. F., Bowman, M., Smith, R., Lewis, J. G., Denison, F. C., Forbes, S., Seckl, J. R., Walker, B. R., Norman, J. E. & Reynolds, R. M., 25 Sep 2015, In : Psychoneuroendocrinology. 63, p. 135-143 9 p.

    Research output: Contribution to journalArticle

  20. Islet transplantation from a nationally funded UK centre reaches socially deprived groups and improves metabolic outcomes

    Forbes, S., McGowan, N. W. A., Duncan, K., Anderson, D., Barclay, J., Mitchell, D., Docherty, K., Turner, D., Campbell, J. D. M. & Casey, J., Jun 2015, In : Diabetologia. 58, 6, p. 1300-1308

    Research output: Contribution to journalArticle

  21. Efficacy of metformin in pregnant obese women: a randomised controlled trial

    Chiswick, C. A., Reynolds, R. M., Denison, F. C., Whyte, S. A., Drake, A. J., Newby, D. E., Walker, B. R., Forbes, S., Murray, G. D., Quenby, S., Wray, S. & Norman, J. E., 14 Jan 2015, In : BMJ Open. 5, 1, p. e006854

    Research output: Contribution to journalArticle

  22. 2014
  23. Home urine C-peptide creatinine ratio can be used to monitor islet transplant function

    Oram, R. A., Brooks, A. M., Forbes, S., Eckoldt, S., Smith, R. M., Choudhary, P., Rosenthal, M. J., Johnson, P., Rutter, M. K., Burling, K. A., McDonald, T. J., Shaw, J. A. M. & Hattersley, A. T., Jun 2014, In : Diabetes Care. 37, 6, p. 1737-40 4 p.

    Research output: Contribution to journalArticle

  24. Abdominal fat changes and intrahepatic fat deposition post islet transplantation: A first look

    Mistry, B., Ukkonen, A., Forbes, S. & Gray, C. D., 2014, 20th Annual Scientific Meeting of the British Chapter of ISMRM.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  25. 2013
  26. Attainment of Metabolic Goals in the Integrated UK Islet Transplant Program With Locally Isolated and Transported Preparations

    Brooks, A. M., Walker, N., Aldibbiat, A., Hughes, S., Jones, G., de Havilland, J., Choudhary, P., Huang, G. C., Parrott, N., McGowan, N. W. A., Casey, J., Mumford, L., Barker, P., Burling, K., Hovorka, R., Walker, M., Smith, R. M., Forbes, S., Rutter, M. K., Amiel, S. & 3 others, Rosenthal, M. J., Johnson, P. & Shaw, J. A. M., Dec 2013, In : American Journal of Transplantation. 13, 12, p. 3236-3243 8 p.

    Research output: Contribution to journalArticle

  27. A history of previous gestational diabetes mellitus is associated with adverse changes in insulin secretion and VLDL metabolism independently of increased intrahepatocellular lipid

    Forbes, S., Godsland, I. F., Taylor-Robinson, S. D., Bell, J. D., Thomas, E. L., Patel, N., Hamilton, G., Parker, K. H., Marshall, I., Gray, C. D., Bedford, D., Caslake, M., Walker, B. R. & Johnston, D. G., Sep 2013, In : Diabetologia. 56, 9, p. 2021-2033 13 p.

    Research output: Contribution to journalArticle

  28. Suppression of Epithelial to Mesenchymal Transitioning (EMT) Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue towards Functional Insulin Producing β-Like Cells

    Lima, M. J., Muir, K. R., Docherty, H. M., Drummond, R., McGowan, N. W. A., Forbes, S., Heremans, Y., Houbracken, I., Ross, J. A., Forbes, S. J., Ravassard, P., Heimberg, H., Casey, J. & Docherty, K., Aug 2013, In : Diabetes. 62, 8, p. 2821-2833 13 p.

    Research output: Contribution to journalArticle

  29. Islet transplantation and return of hypoglycaemic awareness: the same Driver and Vehicle Licensing Agency (DVLA) rules still apply

    Forbes, S. & Shaw, J. A. M., Jul 2013, In : Diabetic Medicine. 30, 7, p. 886-886 1 p.

    Research output: Contribution to journalLetter

  30. Outcomes in subjects with Type 1 diabetes following islet transplantation in the Scottish islet transplant programme

    Forbes, S., McGilvray, T., Davidson, J., Duncan, K., Jansen, C., Barclay, J., Anderson, D., McGowan, N. & Casey, J., Mar 2013, In : Diabetic Medicine. 30, p. 87-87 1 p.

    Research output: Contribution to journalMeeting abstract

  31. Quantification of hepatic steatosis before and after intraportal pancreatic islet transplantation

    Ahmmed, A. A., Brooks, A. M. S., Hollingsworth, K. G., Trenell, M., Choudhary, P., Amiel, S. A., Rosenthal, M., Forbes, S., Rutter, M. K., Taylor, R. & Shaw, J. A. M., Mar 2013, In : Diabetic Medicine. 30, p. 59-59 1 p.

    Research output: Contribution to journalMeeting abstract

  32. Reduction in body weight, fat mass and waist circumference secondary to reduced calorific intake following islet transplantation in subjects with Type 1 diabetes in Scotland

    Anderson, D., Duncan, K., Barclay, J., Jansen, C., McGilvary, T., Davidson, J., McGowan, N., Casey, J. & Forbes, S., Mar 2013, In : Diabetic Medicine. 30, p. 15-15 1 p.

    Research output: Contribution to journalMeeting abstract

  33. Urine c-peptide creatinine ratio can be used for home monitoring of islet transplant function

    Oram, R. A., Brooks, A. M. S., Smith, R., Rutter, M. K., Johnson, P. R., Choudhary, P., Rosenthal, M., Forbes, S., McDonald, T. J., Hattersley, A. T. & Shaw, J. A. M., Mar 2013, In : Diabetic Medicine. 30, p. 87-87 1 p.

    Research output: Contribution to journalMeeting abstract

  34. Weight management guides for pregnant women with a body mass index (BMI) ≥ 40kg/m2: A qualitative exploration of their use in maternity care

    Smith, D. M., Ward, C., Forbes, S., Reynolds, R. M. & Denison, F. C., Mar 2013, In : Health Education Journal. 72, 2, p. 216-221 6 p.

    Research output: Contribution to journalArticle

  35. 2012
  36. Evaluation of kisspeptin levels in obese pregnancy as a biomarker for pre-eclampsia

    Logie, J. J., Denison, F. C., Riley, S. C., Ramaesh, T., Forbes, S., Norman, J. E. & Reynolds, R. M., Jun 2012, In : Clinical Endocrinology. 76, 6, p. 887-893 7 p.

    Research output: Contribution to journalArticle

  37. 2011
  38. Anxiety and Depression in Severely Obese Pregnancy: Associations with Gestational Weight Gain and Birthweight

    Reynolds, R. M., Forbes, S., Mohd-Shukri, N., Craighead, F. H., Smith, R. N., Denison, F. C. & Norman, J. E., Sep 2011, In : Journal of the Developmental Origins of Health and Disease. 2, p. S32-S32 1 p.

    Research output: Contribution to journalMeeting abstract

  39. Diet and Physical Activity in Severely Obese Pregnancy: Associations with Gestational Weight Gain and Birthweight

    Mohd-Shukri, N. A., Bolton, J., Forbes, S., Denison, F. C., Norman, J. E., Walker, B. R. & Reynolds, R. M., Sep 2011, In : Journal of the Developmental Origins of Health and Disease. 2, p. S93-S93 1 p.

    Research output: Contribution to journalMeeting abstract

  40. Increased prevalence of non-alcoholic fatty liver disease in European women with a history of gestational diabetes

    Forbes, S., Taylor-Robinson, S. D., Patel, N., Allan, P., Walker, B. R. & Johnston, D. G., Mar 2011, In : Diabetologia. 54, 3, p. 641-647 7 p.

    Research output: Contribution to journalArticle

  41. The use of ultrasound to diagnose hepatic steatosis in type 2 diabetes: intra- and interobserver variability and comparison with magnetic resonance spectroscopy

    Williamson, R. M., Perry, E., Glancy, S., Marshall, I., Gray, C., Nee, L. D., Hayes, P. C., Forbes, S., Frier, B. M., Johnston, G. I., Lee, A. J., Reynolds, R. M., Price, J. F., Strachan, M. W. J. & Edinburgh Type 2 Diabetes Study investigators, 2011, In : Clinical Radiology. 66, 5, p. 434–439 6 p.

    Research output: Contribution to journalArticle

  42. 2010
  43. Relationships between directly measured subcutaneous and visceral adipose, standard anthropometric measures and hepatic steatosis: the Edinburgh Type 2 Diabetes Study

    CA, H., RM, W., Gray, C., Marshall, I., S, G., Forbes, S., BM, F., Reynolds, R., Price, J. & Strachan, M., 1 Mar 2010, In : Diabetic Medicine. 27, Suppl 1, p. 1-36 36 p.

    Research output: Contribution to journalArticle

  44. 2009
  45. The thermic response to food is related to sensitivity to adrenaline in a group at risk for the development of type II diabetes

    Forbes, S., Robinson, S., Parker, K. H., MacDonald, I. A., McCarthy, M. I. & Johnston, D. G., Nov 2009, In : European Journal of Clinical Nutrition. 63, 11, p. 1360-1367 8 p.

    Research output: Contribution to journalArticle

  46. Image Quantification for Diagnosis of Fatty Liver Disease: Magnetic Resonance Imaging and Ultrasound

    Tuthill, T. A., Williamson, R., Gray, C. D., Price, J. F., Glancy, S., Marshall, I., Hayes, P. C., Reynolds, R. M., Forbes, S., Johnston, G. I. & Strachan, M. W. J., 2009, American Institute of Ultrasound in Medicine Conference.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  47. 2008
  48. Glucocorticoids and fatty acid metabolism in humans: fuelling fat redistribution in the metabolic syndrome

    Macfarlane, D. P., Forbes, S. & Walker, B. R., May 2008, In : Journal of Endocrinology. 197, 2, p. 189-204 16 p.

    Research output: Contribution to journalLiterature review

  49. 2006
  50. Sustained endogenous glucose production, diminished lipolysis and non-esterified fatty acid appearance and oxidation in non-obese women at high risk of type 2 diabetes

    Forbes, S., Robinson, S., Dungu, J., Anyaoku, V., Bannister, P., Forster, D., Dissanayake, S., McCarthy, M. I., MacDonald, I. A., Venkatesan, S. & Johnston, D. G., Sep 2006, In : European Journal of Endocrinology. 155, 3, p. 469-76 8 p.

    Research output: Contribution to journalArticle

  51. 2005
  52. Impaired circulating glucagon-like peptide-1 response to oral glucose in women with previous gestational diabetes

    Forbes, S., Moonan, M., Robinson, S., Anyaoku, V., Patterson, M., Murphy, K. G., Ghatei, M. A., Bloom, S. R. & Johnston, D. G., Jan 2005, In : Clinical Endocrinology. 62, 1, p. 51-5 5 p.

    Research output: Contribution to journalArticle

  53. 2002
  54. What should we measure in the diabetic patient and how does this respond to therapy?

    Johnston, D. G., Robinson, S. & Forbes, S., Jul 2002, In : British Journal of Clinical Pharmacology. 54, 1, p. 81-6 6 p.

    Research output: Contribution to journalArticle