Edinburgh Research Explorer

Prof Tara Spires-Jones

Personal Chair of Neurodegeneration

  1. 2019
  2. Beyond the neuron - Cellular interactions early in Alzheimer’s disease pathogenesis

    Henstridge, C., Hyman, B. & Spires-Jones, T. 14 Jan 2019 In : Nature Reviews Neuroscience.

    Research output: Contribution to journalReview article

  3. 2018
  4. Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

    Stevenson, A., McCartney, D. L., Harris, S., Taylor, A., Redmond, P., Starr, J., Zhang, Q., McRae, A. F., Wray, N. R., Spires-Jones, T., McColl, B., McIntosh, A., Deary, I. & Marioni, R. 20 Dec 2018 In : Clinical epigenetics.

    Research output: Contribution to journalArticle

  5. Complementing tau: new data shows the complement system is involved in degeneration in tauopathies

    Davies, C. & Spires-Jones, T. 19 Dec 2018 In : Neuron. 100, 6

    Research output: Contribution to journalReview article

  6. APOE at the interface of inflammation, neurodegeneration and pathological protein spread in Alzheimer's disease

    Tzioras, M., Davies, C., Newman, A., Jackson, R. & Spires-Jones, T. 5 Nov 2018 In : Neuropathology and Applied Neurobiology.

    Research output: Contribution to journalArticle

  7. Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease

    Pickett, E., Rose, J., McCrory, C., McKenzie, C-A., King, D., Smith, C., Gillingwater, T., Henstridge, C. & Spires-Jones, T. 6 Sep 2018 In : Acta Neuropathologica.

    Research output: Contribution to journalArticle

  8. Modeling Alzheimer’s disease brains in Vitro

    Henstridge, C. & Spires-Jones, T. 27 Jun 2018 In : Nature Neuroscience. 21

    Research output: Contribution to journalEditorial

  9. sAPPβ and sAPPα increase structural complexity and E/I input ratio in primary hippocampal neurons and alter Cahomeostasis and CREB1-signaling

    Hesse, R., von Einem, B., Wagner, F., Bott, P., Schwanzar, D., Jackson, R. J., Föhr, K. J., Lausser, L., Kroker, K. S., Proepper, C., Walther, P., Kestler, H. A., Spires-Jones, T. L., Boeckers, T., Rosenbrock, H. & von Arnim, C. A. F. Jun 2018 In : Experimental neurology. 304, p. 1-13 13 p.

    Research output: Contribution to journalArticle

  10. Synaptogyrin-3 mediates presynaptic dysfunction induced by Tau

    McInnes, J., Wierda, K., Snellinx, A., Wang, Y-C., Stancu, I-C., Apostolo, N., Gevaert, K., Dewachter, I., Spires-Jones, T., De Strooper, B., De Wit, J., Zhou, L. & Verstreken, P. 1 Feb 2018 In : Neuron.

    Research output: Contribution to journalArticle

  11. Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis

    Henstridge, C. M., Sideris, D. I., Carroll, E., Rotariu, S., Salomonsson, S., Tzioras, M., McKenzie, C-A., Smith, C., von Arnim, C. A. F., Ludolph, A. C., Lulé, D., Leighton, D., Warner, J., Cleary, E., Newton, J., Swingler, R., Chandran, S., Gillingwater, T. H., Abrahams, S. & Spires-Jones, T. L. Feb 2018 In : Acta Neuropathologica. 135, 2, p. 213-226

    Research output: Contribution to journalArticle

  12. 2017
  13. Antidiabetic polypill improves central pathology and cognitive impairment in a mixed model of Alzheimer's disease and type 2 diabetes

    Infante-Garcia, C., Ramos-Rodriguez , J. J., Hierro-Bujalance, C., Ortegon , S., Pickett, E., Jackson, R., Hernandez-Pacho, F., Spires-Jones, T. & Garcia-Alloza, M. 9 Dec 2017 In : Molecular Neurobiology.

    Research output: Contribution to journalArticle

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