Edinburgh Research Explorer
  1. 2018
  2. Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

    Lempiäinen, H. , Brænne, I. , Michoel, T. , Tragante, V. , Vilne, B. , Webb, T. R. , Kyriakou, T. , Eichner, J. , Zeng, L. , Willenborg, C. , Franzen, O. , Ruusalepp, A. , Goel, A. , Van Der Laan, S. W. , Biegert, C. , Hamby, S. E. , Talukdar, H. A. , Foroughi Asl, H. , Pasterkamp, G. , Watkins, H. & 7 others Samani, N. J., Wittenberger, T., Erdmann, J., Schunkert, H., Asselbergs, F. W., Björkegren, J. L. M. & CVgenes@target consortium 21 Feb 2018 In : Scientific Reports. 8, 1, p. 3434

    Research output: Contribution to journalArticle

  3. 2017
  4. Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity

    Morgan, R. , Beck, K. R. , Nixon, M. , Homer, N. Z. M. , Crawford, A. A. , Melchers, D. , Houtman, R. , Meijer, O. C. , Stomby, A. , Anderson, A. J. , Upreti, R. , Stimson, R. H. , Olsson, T. , Michoel, T. , Cohain, A. , Ruusalepp, A. , Schadt, E. E. , Björkegren, J. L. M. , Andrew, R. , Kenyon, C. J. & 4 others Hadoke, P. W. F., Odermatt, A., Keen, J. A. & Walker, B. R. 6 Sep 2017 In : Scientific Reports. 7, 1, p. 10633

    Research output: Contribution to journalArticle

  5. Meta-analysis of Liver and Heart Transcriptomic Data for Functional Annotation Transfer in Mammalian Orthologs

    Reyes, P. F. L., Michoel, T., Joshi, A. & Devailly, G. 26 Aug 2017 In : Computational and Structural Biotechnology Journal. 15, p. 425-432 8 p.

    Research output: Contribution to journalArticle

  6. Efficient and accurate causal inference with hidden confounders from genome-transcriptome variation data

    Wang, L. & Michoel, T. 18 Aug 2017 In : PLoS Computational Biology. 13, 8, p. e1005703

    Research output: Contribution to journalArticle

  7. 2016
  8. Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing

    Schnappauf, O., Beyes, S., Dertmann, A., Freihen, V., Frey, P., Jägle, S., Rose, K., Michoel, T., Grosschedl, R. & Hecht, A. Nov 2016 In : Biochimica et Biophysica Acta-Gene Regulatory Mechanisms. 1859, 11, p. 1353-1367

    Research output: Contribution to journalArticle

  9. Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases

    Franzén, O. , Ermel, R. , Cohain, A. , Akers, N. K. , Di Narzo, A. , Talukdar, H. A. , Foroughi-Asl, H. , Giambartolomei, C. , Fullard, J. F. , Sukhavasi, K. , Köks, S. , Gan, L-M. , Giannarelli, C. , Kovacic, J. C. , Betsholtz, C. , Losic, B. , Michoel, T. , Hao, K. , Roussos, P. , Skogsberg, J. & 3 others Ruusalepp, A., Schadt, E. E. & Björkegren, J. L. M. 19 Aug 2016 In : Science. 353, 6301, p. 827-30 4 p.

    Research output: Contribution to journalArticle

  10. Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

    Pasterkamp, G., van der Laan, S. W., Haitjema, S., Asl, H. F., Siemelink, M. A., Bezemer, T., van Setten, J., Dichgans, M., Malik, R., Worrall, B. B., Schunkert, H., Samani, N. J., de Kleijn, D. P. V., Markus, H. S., Hoefer, I. E., Michoel, T., de Jager, S. C. A., Björkegren, J. L. M., den Ruijter, H. M. & Asselbergs, F. W. Jun 2016 In : Arteriosclerosis, thrombosis, and vascular biology. 36, 6, p. 1240-1246

    Research output: Contribution to journalArticle

  11. Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease

    Talukdar, H. A., Asl, H. F., Jain, R. K., Ermel, R., Ruusalepp, A., Franzén, O., Kidd, B. A., Readhead, B., Giannarelli, C., Kovacic, J. C., Ivert, T., Dudley, J. T., Civelek, M., Lusis, A. J., Schadt, E. E., Skogsberg, J., Michoel, T. & Björkegren, J. L. M. 23 Mar 2016 In : Cell Systems. 2, 3, p. 196-208

    Research output: Contribution to journalArticle

  12. Microglial brain region−dependent diversity and selective regional sensitivities to aging

    Renault, K., Michoel, T., Karavolos, M., Clohisey, S., Baillie, J., Stevens, M., Freeman, T., Summers, K. & McColl, B. Mar 2016 In : Nature Neuroscience. 19, 3, p. 504-516

    Research output: Contribution to journalArticle

  13. An Algorithm to Automatically Generate the Combinatorial Orbit Counting Equations

    Melckenbeeck, I., Audenaert, P., Michoel, T., Colle, D. & Pickavet, M. 21 Jan 2016 In : PLoS One. 11, 1, e0147078

    Research output: Contribution to journalArticle

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