Edinburgh Research Explorer

Simon Cox

Senior Research Fellow

  1. Associations between vascular risk factors and brain MRI indices in UK Biobank

    Cox, S., Lyall, D. M., Ritchie, S., Bastin, M., Harris, M., Buchanan, C. R., Fawns-Ritchie, C., Barbu, M., de Nooij, L., Reus, L. M., Alloza, C., Shen, X., Neilson, E., Alderson, H. L., Hunter, S., Liewald, D., Whalley, H. C., McIntosh, A., Lawrie, S., Pell, J. P. & 4 others, Tucker-Drob, E. M., Wardlaw, J., Gale, C. & Deary, I., 11 Mar 2019, In: European Heart Journal.

    Research output: Contribution to journalArticlepeer-review

  2. Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936

    Crook, A., Booth, T., Cox, S., Corley, J., Dykiert, D., Redmond, P., Pattie, A., Taylor, A., Harris, S., Starr, J. & Deary, I., 16 Feb 2018, In: PLoS ONE. 13, 2, 20 p., e0192604.

    Research output: Contribution to journalArticlepeer-review

  3. An automated machine learning approach to predict brain age from cortical anatomical measures

    Dafflon, J., Pinaya, W. H. L., Turkheimer, F., Cole, J. H., Leech, R., Harris, M. A., Cox, S. R., Whalley, H. C., Mcintosh, A. M. & Hellyer, P. J., 16 May 2020, In: Human Brain Mapping.

    Research output: Contribution to journalArticlepeer-review

  4. Characteristics of a protocol to collect objective physical activity/sedentary behaviour data in a large study: Seniors USP (understanding sedentary patterns

    Dall, P. M., Skelton, D. A., Dontje, M. L., Coulter, E., Stewart, S., Cox, S., Shaw, R. J., Čukić, I., Fitzsimons, C., Greig, C. A., Granat, M. H., Der, G., Deary, I. & Chastin, S. F. M., 31 Mar 2018, In: Journal of the Measurement of Physical Behaviour. 1, 1, p. 26-31

    Research output: Contribution to journalArticlepeer-review

  5. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P., Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S-C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L-P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 1 May 2019, In: Nature Communications. 10, 1, p. 2068

    Research output: Contribution to journalArticle

  6. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P., Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., Mcintosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., 29 May 2018, In: Nature Communications. 9, 1, p. 1-16 2098.

    Research output: Contribution to journalArticlepeer-review

  7. Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

    Davies, G., Marioni, R. E., Liewald, D. C., Hill, W. D., Hagenaars, S. P., Harris, S. E., Ritchie, S. J., Luciano, M., Fawns-ritchie, C., Lyall, D., Cullen, B., Cox, S. R., Hayward, C., Porteous, D. J., Evans, J., Mcintosh, A. M., Gallacher, J., Craddock, N., Pell, J. P., Smith, D. J. & 2 others, Gale, C. R. & Deary, I. J., 30 Jun 2016, In: Molecular Psychiatry. 21, 6, p. 758-767 10 p.

    Research output: Contribution to journalArticlepeer-review

  8. Getting Spearman off the skyhook: One more in a century (since Thomson, 1916) of attempts to vanquish g

    Deary, I., Cox, S. & Ritchie, S. J., 2 Aug 2016, In: Psychological Inquiry. 27, 3, p. 192-199

    Research output: Contribution to journalArticlepeer-review

  9. Brain peak width of skeletonised mean diffusivity (PSMD) and cognitive function in later life

    Deary, I., Ritchie, S. J., Muñoz Maniega, S., Cox, S., Valdes Hernandez, M., Luciano, M., Starr, J., Wardlaw, J. & Bastin, M., 26 Jul 2019, In: Frontiers in psychiatry. 10, 524.

    Research output: Contribution to journalArticlepeer-review

  10. Cognitive functioning and lifetime major depressive disorder in UK Biobank

    De nooij, L., Harris, M. A., Adams, M. J., Clarke, T., Shen, X., Cox, S. R., Mcintosh, A. M. & Whalley, H. C., 21 Feb 2020, In: European Psychiatry. 63, 1

    Research output: Contribution to journalArticlepeer-review

  11. Progression of white matter disease and cortical thinning are not related in older community-dwelling subjects

    Dickie, D. A., Karama, S., Ritchie, S. J., Cox, S. R., Sakka, E., Royle, N. A., Aribisala, B. S., Hernández, M. V., Maniega, S. M., Pattie, A., Corley, J., Starr, J. M., Bastin, M. E., Evans, A. C., Deary, I. J. & Wardlaw, J. M., 22 Dec 2015, In: Stroke. 47, 2, p. 410-6 7 p.

    Research output: Contribution to journalArticlepeer-review

  12. Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936

    Dickie, D. A., Ritchie, S. J., Cox, S., Sakka, E., Royle, N., Aribisala, B., Valdes Hernandez, M., Muñoz Maniega, S., Pattie, A., Corley, J., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Jun 2016, In: Neurobiology of Aging. 42, p. 116-123

    Research output: Contribution to journalArticlepeer-review

  13. Do demographic and vascular risk factors predict cognitive change in 11,070 UK Biobank participant?

    Fawns-Ritchie, C., Cox, S., Richards, M., Gallacher, J. E., Starr, J. & Deary, I., 2017, In: Alzheimer's & Dementia. 13, 7, Supplement , p. P1556 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  14. Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936

    Field, T. S., Doubal, F., Johnson, W., Backhouse, E., McHutchison, C., Cox, S., Corley, J., Pattie, A., Gow, A., Shenkin, S., Cvoro, V., Morris, Z., Staals, J., Bastin, M., Deary, I. & Wardlaw, J., 19 Sep 2016, In: Aging. 8, 9, p. 2039-2061

    Research output: Contribution to journalArticlepeer-review

  15. Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder

    Green, C., Shen, X., Stevenson, A. J., Conole, E. L. S., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., Lawrie, S. M., Evans, K. L., Walker, R. M., Morris, S. W., Porteous, D. J., Wardlaw, J. M., Douglas Steele, J., Waiter, G. D., Sandu, A., Campbell, A., Marioni, R. E. & 4 others, Cox, S. R., Cavanagh, J., Mcintosh, A. M. & Whalley, H. C., 19 Nov 2020, In: Brain, Behavior, and Immunity.

    Research output: Contribution to journalArticlepeer-review

  16. Genetic contributions to trail making test performance in UK Biobank

    Hagenaars, S., Cox, S., Hill, W. D., Davies, G., Liewald, D., Consortium, CHARGE., Harris, S., McIntosh, A., Gale, C. & Deary, I., Jul 2018, In: Molecular Psychiatry. 23, 7, p. 1575-1583

    Research output: Contribution to journalArticlepeer-review

  17. Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

    Harris, S. E., Marioni, R. E., Martin-Ruiz, C., Pattie, A., Gow, A. J., Cox, S. R., Corley, J., von Zglinicki, T., Starr, J. M. & Deary, I. J., Mar 2016, In: Mechanisms of Ageing and Development. 154, p. 43-48 6 p.

    Research output: Contribution to journalArticlepeer-review

  18. Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

    Harris, S., Cox, S., Bell, S., Marioni, R., Prins, B. P., Pattie, A., Corley, J., Muñoz Maniega, S., Valdes Hernandez, M., Morrison, Z., John, S. L., Bronson, P. G., Tucker-Drob, E. M., Starr, J., Bastin, M., Wardlaw, J., Butterworth, A. S. & Deary, I., 10 Feb 2020, In: Nature Communications. 11, 800.

    Research output: Contribution to journalArticlepeer-review

  19. Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936

    Harris, S. E., Riggio, V., Evenden, L., Gilchrist, T., Mccafferty, S., Murphy, L., Wrobel, N., Taylor, A. M., Corley, J., Pattie, A., Cox, S. R., Martin-ruiz, C., Prendergast, J., Starr, J. M., Marioni, R. E. & Deary, I. J., 1 Dec 2017, In: Aging. 9, 12, p. 2489-2503

    Research output: Contribution to journalArticlepeer-review