Edinburgh Research Explorer

Simon Cox

Senior Research Fellow

  1. 2012
  2. 2013
  3. Assessing the performance of atlas-based prefrontal brain parcellation in an aging cohort

    Aribisala, B. S., Cox, S. R., Ferguson, K. J., MacPherson, S. E., Maclullich, A. M. J., Royle, N. A., Valdés Hernández, M. C., Bastin, M. E., Deary, I. J. & Wardlaw, J. M., Mar 2013, In: Journal of computer assisted tomography. 37, 2, p. 257-264 8 p.

    Research output: Contribution to journalArticlepeer-review

  4. 2014
  5. A systematic review of brain frontal lobe parcellation techniques in magnetic resonance imaging

    Cox, S. R., Ferguson, K. J., Royle, N. A., Shenkin, S. D., MacPherson, S. E., Maclullich, A. M. J., Deary, I. J. & Wardlaw, J. M., Jan 2014, In: Brain Structure and Function. 219, 1, p. 1-22 22 p.

    Research output: Contribution to journalArticlepeer-review

  6. Genetic and environmental exposures constrain epigenetic drift over the human life course

    Shah, S., Mcrae, A. F., Marioni, R. E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Starr, J. M., Wray, N. R., Deary, I. & Visscher, P. M., 1 Nov 2014, In: Genome Research. 24, 11, p. 1725-1733

    Research output: Contribution to journalArticlepeer-review

  7. 2015
  8. Brain white matter integrity and cortisol in older men: the Lothian Birth Cohort 1936

    Cox, S. R., Bastin, M. E., Ferguson, K. J., Munoz-Maniega, S., MacPherson, S. E., Deary, I. J., Wardlaw, J. M. & MacLullich, A. M. J., 2015, In: Neurobiology of Aging. 36, 1, p. 257-264 8 p.

    Research output: Contribution to journalArticlepeer-review

  9. Brain white matter structure and information processing speed in healthy older age

    Kuznetsova, K., Munoz-Maniega, S., Ritchie, S., Cox, S., Storkey, A., Starr, J., Wardlaw, J., Deary, I. & Bastin, M., 2015, In: Brain Structure and Function. 21, 6, p. 3323-3235

    Research output: Contribution to journalArticlepeer-review

  10. Neural mechanisms of Trail Making Test performance

    MacPherson, S. E., Cox, S., Aribisala, B., Bastin, M., Wardlaw, J. & Deary, I., 2015, (Unpublished).

    Research output: Contribution to conferencePaperpeer-review

  11. The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

    Marioni, R. E., Shah, S., McRae, A. F., Ritchie, S. J., Muniz-Terrera, G., Harris, S. E., Gibson, J., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Taylor, A., Murphy, L., Starr, J. M., Horvath, S., Visscher, P. M., Wray, N. R. & Deary, I. J., 2015, In: International Journal of Epidemiology. 44, 4, p. 1388-1396

    Research output: Contribution to journalArticlepeer-review

  12. DNA methylation age of blood predicts all-cause mortality in later life

    Marioni, R. E., Shah, S., McRae, A. F., Chen, B. H., Colicino, E., Harris, S. E., Gibson, J., Henders, A. K., Redmond, P., Cox, S. R., Pattie, A., Corley, J., Murphy, L., Martin, N. G., Montgomery, G. W., Feinberg, A. P., Fallin, M. D., Multhaup, M. L., Jaffe, A. E., Joehanes, R. & 11 others, Schwartz, J., Just, A. C., Lunetta, K. L., Murabito, J. M., Starr, J. M., Horvath, S., Baccarelli, A. A., Levy, D., Visscher, P. M., Wray, N. R. & Deary, I. J., 30 Jan 2015, In: Genome Biology. 16, 12 p., 25.

    Research output: Contribution to journalArticlepeer-review

  13. Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

    Clarke, T-K., Lupton, M. K., Fernandez-Pujals, A. M., Starr, J., Davies, G., Cox, S., Pattie, A., Liewald, D. C., Hall, L. S., MacIntyre, D. J., Smith, B. H., Hocking, L. J., Padmanabhan, S., Thomson, P. A., Hayward, C., Hansell, N. K., Montgomery, G. W., Medland, S. E., Martin, N. G., Wright, M. J. & 3 others, Porteous, D. J., Deary, I. J. & McIntosh, A. M., 10 Mar 2015, In: Molecular Psychiatry.

    Research output: Contribution to journalArticlepeer-review

  14. Handbook of Frontal Lobe Assessment

    MacPherson, S. E., Della Sala, S., Cox, S. R., Girardi, A. & Iveson, M., 7 May 2015, Oxford: Oxford University Press. 448 p.

    Research output: Book/ReportBook

  15. Coupled changes in brain white matter microstructure and fluid intelligence in later life

    Ritchie, S., Bastin, M., Tucker-Drob, E. M., Munoz-Maniega, S., Engelhardt, L., Cox, S. R., Royle, N., Gow, A., Corley, J., Pattie, A., Taylor, A., Valdes Hernandez, M., Starr, J., Wardlaw, J. & Deary, I., 3 Jun 2015, In: The Journal of Neuroscience. 35, 22, p. 8672-8682 11 p.

    Research output: Contribution to journalArticlepeer-review

  16. Post-mortem brain analyses of the Lothian Birth Cohort 1936: Extending lifetime cognitive and brain phenotyping to the level of the synapse

    Henstridge, C., JAckson, R., Kim, J., Herrmann, A., Wright, A. K., Harris, S., Bastin, M., Starr, J., Wardlaw, J., Gillingwater, T., Smith, C., McKenzie, C-A., Cox, S., Deary, I. & Spires-Jones, T., 4 Sep 2015, In: Acta Neuropathologica Communications. 3, 53

    Research output: Contribution to journalArticlepeer-review

  17. Brain volumetric changes and cognitive ageing during the eighth decade of life

    Ritchie, S. J., Dickie, D., Cox, S., Valdes Hernandez, M., Corley, J., Royle, N., Pattie, A., Aribisala, B., Redmond, P., Munoz-Maniega, S., Taylor, A., Sibbett, R., Gow, A., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Dec 2015, In: Human Brain Mapping. 36, p. 4910–4925

    Research output: Contribution to journalArticlepeer-review

  18. Progression of white matter disease and cortical thinning are not related in older community-dwelling subjects

    Dickie, D. A., Karama, S., Ritchie, S. J., Cox, S. R., Sakka, E., Royle, N. A., Aribisala, B. S., Hernández, M. V., Maniega, S. M., Pattie, A., Corley, J., Starr, J. M., Bastin, M. E., Evans, A. C., Deary, I. J. & Wardlaw, J. M., 22 Dec 2015, In: Stroke. 47, 2, p. 410-6 7 p.

    Research output: Contribution to journalArticlepeer-review

  19. 2016
  20. Volumetric and correlational implications of brain parcellation method selection: a 3-way comparison in the frontal lobes.

    Cox, S., McKenzie, T., Aribisala, B., Royle, N., MacPherson, S. E., Maclullich, A., Bastin, M., Wardlaw, J., Deary, I. & Ferguson, K., 2016, In: Journal of computer assisted tomography. 40, p. 53-60

    Research output: Contribution to journalArticlepeer-review

  21. Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921

    Harris, S. E., Marioni, R. E., Martin-Ruiz, C., Pattie, A., Gow, A. J., Cox, S. R., Corley, J., von Zglinicki, T., Starr, J. M. & Deary, I. J., Mar 2016, In: Mechanisms of Ageing and Development. 154, p. 43-48 6 p.

    Research output: Contribution to journalArticlepeer-review

  22. Trait Conscientiousness and the Personality Meta-Trait Stability are Associated with Regional White Matter Microstructure

    Lewis, G. J., Cox, S., Booth, T., Muñoz Maniega, S., Royle, N., Valdes Hernandez, M., Wardlaw, J., Bastin, M. & Deary, I., 24 Mar 2016, In: Social Cognitive and Affective Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  23. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

    Okbay, A., Baselmans, B. M. L., De Neve, J-E., Turley, P., Nivard, M. G., Fontana, M. A., Meddens, S. F. W., Linnér, R. K., Rietveld, C. A., Derringer, J., Gratten, J., Lee, J. J., Liu, J. Z., de Vlaming, R., Ahluwalia, T. S., Buchwald, J., Cavadino, A., Frazier-Wood, A. C., Furlotte, N. A., Garfield, V. & 31 others, Geisel, M. H., Gonzalez, J. R., Haitjema, S., Karlsson, R., van der Laan, S. W., Ladwig, K-H., Lahti, J., van der Lee, S. J., Lind, P. A., Liu, T., Matteson, L., Mihailov, E., Miller, M. B., Minica, C. C., Nolte, I. M., Mook-Kanamori, D., van der Most, P. J., Oldmeadow, C., Qian, Y., Raitakari, O., Rawal, R., Realo, A., Rueedi, R., Schmidt, B., Cox, S. R., Davies, G., Pattie, A., Rudan, I., Deary, I. J., Hayward, C. & LifeLines Cohort Study, 18 Apr 2016, In: Nature Genetics. 48, p. 624-633

    Research output: Contribution to journalArticlepeer-review

  24. Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936

    Dickie, D. A., Ritchie, S. J., Cox, S., Sakka, E., Royle, N., Aribisala, B., Valdes Hernandez, M., Muñoz Maniega, S., Pattie, A., Corley, J., Starr, J., Bastin, M., Deary, I. & Wardlaw, J., Jun 2016, In: Neurobiology of Aging. 42, p. 116-123

    Research output: Contribution to journalArticlepeer-review

  25. Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151)

    Davies, G., Marioni, R. E., Liewald, D. C., Hill, W. D., Hagenaars, S. P., Harris, S. E., Ritchie, S. J., Luciano, M., Fawns-ritchie, C., Lyall, D., Cullen, B., Cox, S. R., Hayward, C., Porteous, D. J., Evans, J., Mcintosh, A. M., Gallacher, J., Craddock, N., Pell, J. P., Smith, D. J. & 2 others, Gale, C. R. & Deary, I. J., 30 Jun 2016, In: Molecular Psychiatry. 21, 6, p. 758-767 10 p.

    Research output: Contribution to journalArticlepeer-review

  26. Getting Spearman off the skyhook: One more in a century (since Thomson, 1916) of attempts to vanquish g

    Deary, I., Cox, S. & Ritchie, S. J., 2 Aug 2016, In: Psychological Inquiry. 27, 3, p. 192-199

    Research output: Contribution to journalArticlepeer-review

  27. Bilingualism, social cognition and executive functions: A tale of chickens and eggs

    Cox, S. R., Bak, T. H., Allerhand, M., Redmond, P., Starr, J. M., Deary, I. J. & MacPherson, S. E., 29 Aug 2016, In: Neuropsychologia. 91, p. 299-306

    Research output: Contribution to journalArticlepeer-review

  28. Information processing speed mediates the relationship between white matter and general intelligence in schizophrenia

    Alloza, C., Cox, S., Duff, B., Semple, S., Bastin, M., Whalley, H. & Lawrie, S., 31 Aug 2016, In: Psychiatry Research-Neuroimaging. 254, p. 26-33

    Research output: Contribution to journalArticlepeer-review

  29. Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936

    Field, T. S., Doubal, F., Johnson, W., Backhouse, E., McHutchison, C., Cox, S., Corley, J., Pattie, A., Gow, A., Shenkin, S., Cvoro, V., Morris, Z., Staals, J., Bastin, M., Deary, I. & Wardlaw, J., 19 Sep 2016, In: Aging. 8, 9, p. 2039-2061

    Research output: Contribution to journalArticlepeer-review

  30. Associations between education and brain structure at age 73 years, adjusted for age 11 IQ

    Cox, S., Dickie, D. A., Ritchie, S. J., Karama, S., Pattie, A., Royle, N., Corley, J., Aribisala, B., Valdes Hernandez, M. C., Muñoz Maniega, S., Starr, J., Bastin, M., Evans, A. C., Wardlaw, J. & Deary, I., Oct 2016, In: Neurology. 87, 17, p. 1820-1826 7 p.

    Research output: Contribution to journalArticlepeer-review

  31. The frontal ageing hypothesis: Evidence from normal ageing and dementia

    MacPherson, S. E. & Cox, S. R., 17 Nov 2016, Handbook of Gerontology Research Methods: Understanding Successful Aging. Riby, L. (ed.). Blackwell, (Research Methods in Developmental Psychology: A Handbook Series).

    Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

  32. Genome-wide analysis identifies 12 loci influencing human reproductive behavior

    Barban, N., Jansen, R., de Vlaming, R., Vaez, A., Mandemakers, J., Tropf, F. C., Shen, X., Wilson, J. F., Chasman, D. I., Nolte, I. M., Tragante, V., van der Laan, S. W., Perry, J. R. B., Kong, A., BIOS Consortium, Ahluwalia, T. S., Albrecht, E., Yerges-Armstrong, L., Atzmon, G., Auro, K. & 235 others, Ayers, K., Bakshi, A., Ben-Avraham, D., Berger, K., Bergman, A., Bertram, L., Bielak, L. F., Bjornsdottir, G., Bonder, M. J., Broer, L., Bui, M., Barbieri, C., Cavadino, A., Chavarro, J. E., Turman, C., Concas, M. P., Cordell, H. J., Davies, G., Eibich, P., Eriksson, N., Esko, T., Eriksson, J., Falahi, F., Felix, J. F., Fontana, M. A., Franke, L., Gandin, I., Gaskins, A. J., Gieger, C., Gunderson, E. P., Guo, X., Hayward, C., He, C., Hofer, E., Huang, H., Joshi, P. K., Kanoni, S., Karlsson, R., Kiechl, S., Kifley, A., Kluttig, A., Kraft, P., Lagou, V., Lecoeur, C., Lahti, J., Li-Gao, R., Lind, P. A., Liu, T., Makalic, E., Mamasoula, C., Matteson, L., Mbarek, H., McArdle, P. F., McMahon, G., Meddens, S. F. W., Mihailov, E., Miller, M., Missmer, S. A., Monnereau, C., van der Most, P. J., Myhre, R., Nalls, M. A., Nutile, T., Kalafati, I. P., Porcu, E., Prokopenko, I., Rajan, K. B., Rich-Edwards, J., Rietveld, C. A., Robino, A., Rose, L. M., Rueedi, R., Ryan, K. A., Saba, Y., Schmidt, D., Smith, J. A., Stolk, L., Streeten, E., Tönjes, A., Thorleifsson, G., Ulivi, S., Wedenoja, J., Wellmann, J., Willeit, P., Yao, J., Yengo, L., Zhao, J. H., Zhao, W., Zhernakova, D. V., Amin, N., Andrews, H., Balkau, B., Barzilai, N., Bergmann, S., Biino, G., Bisgaard, H., Bønnelykke, K., Boomsma, D. I., Buring, J. E., Campbell, H., Cappellani, S., Ciullo, M., Cox, S., Cucca, F., Toniolo, D., Davey Smith, G., Deary, I. J., Dedoussis, G., Deloukas, P., van Duijn, C. M., de Geus, E. J. C., Eriksson, J. G., Evans, D. A., Faul, J. D., Sala, C. F., Froguel, P., Gasparini, P., Girotto, G., Grabe, H-J., Greiser, K. H., Groenen, P. J. F., de Haan, H. G., Haerting, J., Harris, T. B., Heath, A. C., Heikkilä, K., Hofman, A., Homuth, G., Holliday, E. G., Hopper, J., Hyppönen, E., Jacobsson, B., Jaddoe, V. W. V., Johannesson, M., Jugessur, A., Kähönen, M., Kajantie, E., Kardia, S. L. R., Keavney, B., Kolcic, I., Koponen, P., Kovacs, P., Kronenberg, F., Kutalik, Z., La Bianca, M., Lachance, G., Iacono, W. G., Lai, S., Lehtimäki, T., LifeLines Cohort Study, Liewald, D., Lindgren, C. M., Liu, Y., Luben, R., Lucht, M., Luoto, R., Magnus, P., Magnusson, P. K. E., Martin, N. G., McGue, M., McQuillan, R., Medland, S. E., Meisinger, C., Mellström, D., Metspalu, A., Traglia, M., Milani, L., Mitchell, P., Montgomery, G. W., Mook-Kanamori, D. O., de Mutsert, R., Nohr, E. A., Ohlsson, C., Olsen, J., Ong, K. K., Paternoster, L., Pattie, A., Penninx, B. W. J. H., Perola, M., Peyser, P. A., Pirastu, M., Polasek, O., Power, C., Kaprio, J., Raffel, L. J., Räikkönen, K., Raitakari, O., Ridker, P. M., Ring, S. M., Roll, K., Rudan, I., Ruggiero, D., Rujescu, D., Salomaa, V., Schlessinger, D., Schmidt, H., Schmidt, R., Schupf, N., Smit, J. H., Sorice, R., Spector, T. D., Starr, J. M., Stöckl, D., Strauch, K., Stumvoll, M., Swertz, M. A., Thorsteinsdottir, U., Thurik, A. R., Timpson, N. J., Tung, J. Y., Uitterlinden, A. G., Vaccargiu, S., Viikari, J., Vitart, V., Völzke, H., Vollenweider, P., Vuckovic, D., Waage, J., Wagner, G. G., Wang, J. J., J Wareham, N., Weir, D. R., Willemsen, G., Willeit, J., Wright, A. F., Zondervan, K. T., Stefansson, K., Krueger, R. F., Lee, J. J., Benjamin, D. J., Cesarini, D., Koellinger, P. D., den Hoed, M., Snieder, H. & Mills, M. C., Dec 2016, In: Nature Genetics. 48, 12, p. 1462–1472 11 p.

    Research output: Contribution to journalArticlepeer-review

  33. Predictors of ageing-related decline across multiple cognitive functions

    Ritchie, S. J., Tucker-drob, E. M., Cox, S. R., Corley, J., Dykiert, D., Redmond, P., Pattie, A., Taylor, A. M., Sibbett, R., Starr, J. M. & Deary, I. J., 10 Dec 2016, In: Intelligence. 59, p. 115-126

    Research output: Contribution to journalArticlepeer-review

  34. Carotid disease at age 73 and cognitive change from age 70 to 76 years. A longitudinal cohort study

    Wardlaw, J., Allerhand, M., Eadie, E., Thomas, A., Corley, J., Pattie, A., Taylor, A., Shenkin, S., Cox, S., Gow, A., Starr, J. & Deary, I., 14 Dec 2016, In: Journal of Cerebral Blood Flow and Metabolism. p. 271678X16683693

    Research output: Contribution to journalArticlepeer-review

  35. Ageing and brain white matter structure in 3513 UK Biobank participants

    Cox, S., Ritchie, S. J., Tucker-Drob, E. M., Liewald, D., Hagenaars, S., Davies, G., Wardlaw, J., Gale, C., Bastin, M. & Deary, I., 15 Dec 2016, In: Nature Communications. 7, p. 1-13 13 p., 13629.

    Research output: Contribution to journalArticlepeer-review

  36. 2017
  37. Do demographic and vascular risk factors predict cognitive change in 11,070 UK Biobank participant?

    Fawns-Ritchie, C., Cox, S., Richards, M., Gallacher, J. E., Starr, J. & Deary, I., 2017, In: Alzheimer's & Dementia. 13, 7, Supplement , p. P1556 1 p.

    Research output: Contribution to journalMeeting abstractpeer-review

  38. Mediterranean-type diet and brain structural change from 73 to 76 years in a Scottish cohort

    Luciano, M., Corley, J., Cox, S., Valdes Hernandez, M., Craig, L., Dickie, D. A., Karama, S., Mcneill, G., Bastin, M., Wardlaw, J. & Deary, I., 31 Jan 2017, In: Neurology. 88, 5, p. 449-455

    Research output: Contribution to journalArticlepeer-review

  39. Stress in childhood, adolescence and early adulthood, and cortisol levels in older age

    Harris, M. A., Cox, S. R., Brett, C. E., Deary, I. J. & MacLullich, A. M. J., Feb 2017, In: Stress. 20, 2, p. 140-148

    Research output: Contribution to journalArticlepeer-review

  40. Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank

    Reus, L., Shen, X., Gibson, J., Wigmore, E., Ligthart, L., Adams, M., Davies, G., Cox, S., Hagenaars, S., Bastin, M., Deary, I., Sibley, H. & McIntosh, A., 10 Feb 2017, In: Scientific Reports. 7, 42140.

    Research output: Contribution to journalArticlepeer-review

  41. Improving data availability for brain image biobanking in healthy subjects: practice-based suggestions from an international multidisciplinary working group

    Shenkin, S. D., Pernet, C., Nichols, T. E., Poline, J. B., Matthews, P. M., van der Lugt, A., Mackay, C. E., Lanyon, L. J., Mazoyer, B., Boardman, J. P., Thompson, P. M., Fox, N. C., Marcus, D. S., Sheikh, A., Cox, S. R., Anblagan, D., Job, D. E., Dickie, D. A., Rodriguez, D. & Wardlaw, J. M., 14 Feb 2017, In: NeuroImage.

    Research output: Contribution to journalArticlepeer-review

  42. Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936

    Valdes Hernandez, M., Cox, S., Kim, J., Royle, N., Muñoz Maniega, S., Gow, A., Anblagan, D., Bastin, M., Park, J., Starr, J., Wardlaw, J. & Deary, I., Apr 2017, In: Neurobiology of Aging. 52, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

  43. Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73-76

    Cox, S., Ritchie, S. J., Dickie, D. A., Pattie, A., Royle, N., Corley, J., Aribisala, B., Harris, S., Valdes Hernandez, M., Gow, A., Muñoz Maniega, S., Starr, J., Bastin, M., Wardlaw, J. & Deary, I., Jun 2017, In: Neurobiology of Aging. 54, p. 54-58

    Research output: Contribution to journalArticlepeer-review

  44. A latent measure explains substantial variance in white matter microstructure across the newborn human brain

    Telford, E., Cox, S., Fletcher-Watson, S., Anblagen, D., Sparrow, S., Pataky, R., Quigley, A., Semple, S., Bastin, M. & Boardman, J., 6 Jun 2017, In: Brain Structure and Function.

    Research output: Contribution to journalArticlepeer-review

  45. Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 Study

    McGrory, S., Taylor, A., Kirin, M., Corley, J., Pattie, A., Cox, S., Dhillon, B., Wardlaw, J., Doubal, F., Starr, J., Trucco, E., MacGillivray, T. & Deary, I., Jul 2017, In: British Journal of Ophthalmology. 101, 7, p. 993-998

    Research output: Contribution to journalArticlepeer-review

  46. Subcortical volume and white matter integrity abnormalities in major depressive disorder: Findings from UK Biobank imaging data

    Shen, X., Reus, L., Cox, S., Adams, M. J., Liewald, D., Bastin, M., Smith, D. J., Deary, I., Sibley, H. & McIntosh, A., 17 Jul 2017, In: Scientific Reports. 7, 1, p. 5547 5547.

    Research output: Contribution to journalArticlepeer-review

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