Edinburgh Research Explorer

William Wallace

(Former employee or visitor)

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Current Research Interests

My research interests focus on lung disease and are rooted in my clinical practice as a diagnostic cardiothoracic pathologist. I have had a long interest in lung injury and remodelling and have well established collaborative links with Professor Sarah Howie in CIR and the Interstitial Lung Disease Clinic, led by Dr Nik Hirani. More recently I have also been involved on research on molecular aspects of lung cancer, particularly in relation to biomarker expression and the use of modern imaging studies to evaluate vascular cardiac valve disease. I have a major interest in projects evaluating and refining the use of specimens submitted for pathological evaluation to optimise the information that can made available for patient care.


I have also worked closely for a number of years with veterinary colleagues looking at pathological aspects of disease in both animal models and in routine practice.


Recent collaborations


  1. Prof Y Ishikawa, Tokyo, Japan. Pathological characteristics of neuroendocrine tumours in lung.
  2. Prof D Newby, Cardiology, Edinburgh University. Pathobiology and imaging of atherosclerostic plaques and degenerative valvular disease.
  3. Dr Gisli Jenkins, Respiratory Medicine, Nottingham University. Expression of matrix proteins in IPF
  4. Prof. Bruce McGorum R(D)SVM, Edinburgh University. Evaluation of idiopathic lung fibrosis in donkeys.
  5. Dr Ian Laurenson, Scottish Mycobacteria Reference Lab, RIE. Evaluation of PCR from paraffin embedded tissue in the diagnosis of tuberculosis.
  6. Prof. DJ Harrison and Myriad Genetics, Salt Lake City, USA. Genetic profiling and prognosis in resected stage 1 and 2 carcinomas of the lung.
  7. CRC UK Stratified Medicine Project
  8. Dr Kris Skwarski, RIE. EBUS FNA cytology in the investigation of mediastinal lympadenopathy of unknown cause.
  9. Dr Emma Rinquist & Dr Judy Allen King’s Buildings, Edinburgh University. Emphysema in mice developing following hook worm infection.


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