Edinburgh Research Explorer

Dr Yvonne Chun

CSO Clinical Academic Fellow, UoE Honorary staff

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Education/Academic qualification

2015Doctor of Philosophy (PhD), University of Edinburgh
Anxiety after Stroke: Intervention Design and a Randomised Controlled Trial
Bachelor of Medicine and Bachelor of Surgery, Imperial College London

Professional Qualifications

2010Membership of the Royal College of Physicians, MRCP

Biography

Yvonne Chun is part of a team of clinical academics including stroke physicians, psychiatrist, clinical trialists and data scientists at the Centre for Clinical Brain Sciences at the University of Edinburgh, Scotland. She was awarded a clinical academic fellowship from the Chief Scientist Office of Scotland to lead and complete a programme of research on anxiety after stroke, which led to the development and pilot testing of a telemedicine guided self-help CBT intervention for anxiety after stroke (TASK-CBT) in a randomised controlled trial (TASK-RCT).

Yvonne plans to take what she learnt from her PhD (completed 2019) forward to incorporate innovative digital technology to improve stroke care and outcomes.

Yvonne is a clinical trialist and is a firm believer of robust testing of new interventions in high quality randomised controlled trials. She designed the TASK RCT using a simple automated clinical trial workflow which aims to empower patients to self-recruit themselves to trials regardless of where they are and to minimise inefficiencies in running large clinical trials. Yvonne has also commenced work on using wrist-worn actigraphy sensors to collect sleep and activity data in clinical studies to investigate how sleep, circadian variability and activity characteristics might be related to stroke outcomes. 

 Yvonne was the chief investigator of TASK randomised controlled trial which demonstrated proof-of-concept of i) the TASK-CBT intervention, ii) a remote efficient clinical trial workflow, and iii) use of wrist-worn actigraphy sensors in stroke and 'mini-stroke' (Transient Ishcaemic Attack).

Yvonne won the Royal College of Physicians of Edinburgh Lindsay Bequest & Reid Trust Research Grant to kickstart a pilot study of using wrist-worn actigraphy sensors to collect objective stroke outcomes in a randomised controlled trial. http://www.rcpe.ac.uk/college/lindsay-bequest-and-reid-trust  

 

The key publications from Yvonne's PhD programme of research are as follows:

Anxiety after stroke: the importance of subtyping (2018).  Stroke. 2018 Mar;49(3):556-564. doi: 10.1161/STROKEAHA.117.020078. Epub 2018 Feb 6.

 Treating anxiety after stroke (TASK): the feasibility phase of a novel web-enabled randomized controlled trial. Pilot Feasibility Stud. 2018 Aug 14;4:139. doi: 10.1186/s40814-018-0329-x. eCollection 2018

A systematic review of anxiety interventions in stroke and acquired brain injury: efficacy and trial design. J Psychosom Res. 2018 Jan; 104:65-75. Doi: 10.1016/j/jpsychores.2017.11.010.  Epub2017 Nov 16

 

Ongoing research interests:

1) Digital health technologies to improve stroke outcomes: telemedicine psychological interventions; wearable devices as outcome measures; automated conversational agent (chatbot) for post-stroke care; patient involvement and co-production in developing health technologies

2) Efficient clinical trial design 

-remote web-enabled clinical trial procedures: recruitment, enrollment, follow-up 

-centralised model 

-web-based intevention usage analytics

 

Potential collaborators can get in touch by email: hchun@exseed.ed.ac.uk or hyychun@gmail.com

twitter: @DrYvonneChun

PhD supervisors: Prof Alan Carson, Prof Martin Dennis, Prof Gillian Mead, Dr William Whiteley

 

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