Determining the role of m cells in tse agent neuroinvasion from the intestine - Edinburgh Research Explorer

Edinburgh Research Explorer

Determining the role of m cells in tse agent neuroinvasion from the intestine

Project: Research

Mabbott, Neil (Principal Investigator)
Mahajan, Arvind (Co-investigator)

Status	Finished
Effective start/end date	1/11/12 → 31/03/16

Total award	£475,896.00
Funding organisation	BBSRC
Funder project reference	BB/J014672/1

Period	1/11/12 → 31/03/16

Project relations

Innate immunity and endemic diseases in livestock species
Project: Research

Press/Media

A case of classical BSE found on Aberdeenshire farm in 2018
Press/Media: Expert Comment

Research outputs

Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium
Research output: Contribution to journal › Article
The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice
Research output: Contribution to journal › Article
Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.
Research output: Contribution to journal › Article
Salmonella transforms follicle-associated epithelial cells into M cells to promote intestinal invasion
Research output: Contribution to journal › Article
Aging impairs the functional maturation of M cells and their ability to sample lumenal antigens
Research output: Contribution to journal › Meeting abstract
The MacBlue Binary Transgene (csf1r-gal4VP16/UAS-ECFP) Provides a Novel Marker for Visualisation of Subsets of Monocytes, Macrophages and Dendritic Cells and Responsiveness to CSF1 Administration
Research output: Contribution to journal › Article
A breakdown in communication? Understanding the effects of aging on the human small intestine
Research output: Contribution to journal › Article
Prospects for safe and effective vaccines against prion diseases
Research output: Contribution to journal › Editorial
The gut-associated lymphoid tissues in the small intestine, not the large intestine, play a major role in oral prion disease pathogenesis
Research output: Contribution to journal › Article
From scientific curiosity to public enemy number one in six short months
Research output: Contribution to journal › Article
The influence of commensal and pathogenic gut microbiota on prion disease pathogenesis
Research output: Contribution to journal › Article
Increased Abundance of M cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility
Research output: Contribution to journal › Article
c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium
Research output: Contribution to journal › Article
The role of CSF1R-dependent macrophages in control of the intestinal stem cell niche
Research output: Contribution to journal › Article
The role of CSF1R-dependent macrophages in control of the intestinal stem cell niche
Research output: Contribution to journal › Article