Future-Proofing the sustainability of the MRC high throughput sequencing hub in Scotland

Project: Research

Blaxter, Mark (Principal Investigator)

School of Biological Sciences

Status	Finished
Effective start/end date	1/10/12 → 30/09/14

Total award	£678,234.00
Funding organisation	MRC
Funder project reference	mr/k001744/1

Period	1/10/12 → 30/09/14

Research outputs

Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken
Research output: Contribution to journal › Article › peer-review
RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification
Research output: Contribution to journal › Article › peer-review
Genomic selection for growth traits in Pacific oyster (Crassostrea gigas): Potential of low-density marker panels for breeding value prediction
Research output: Contribution to journal › Article › peer-review
Differential gene expression is not required for facultative sex allocation: a transcriptome analysis of brain tissue in the parasitoid wasp Nasonia vitripennis
Research output: Contribution to journal › Article › peer-review
High-throughput RNA structure probing reveals critical folding events during early 60S ribosome assembly in yeast
Research output: Contribution to journal › Article › peer-review
Maturation of the 90S pre-ribosome requires Mrd1 dependent U3 snoRNA and 35S pre-rRNA structural rearrangements
Research output: Contribution to journal › Article › peer-review
Gene Duplication and Dosage Effects During The Early Emergence of C4 Photosynthesis in The Grass Genus Alloteropsis
Research output: Contribution to journal › Article › peer-review
Kinetic CRAC uncovers a role for Nab3 in determining gene expression profiles during stress
Research output: Contribution to journal › Article › peer-review
Microglial brain region−dependent diversity and selective regional sensitivities to aging
Research output: Contribution to journal › Article › peer-review
Recombination dynamics of a human Y-chromosomal palindrome: rapid GC-biased gene conversion, multi-kilobase conversion tracts, and rare inversions
Research output: Contribution to journal › Article › peer-review
Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma
Research output: Contribution to journal › Article › peer-review
A genomic portrait of the emergence, evolution, and global spread of a methicillin resistant Staphylococcus aureus pandemic
Research output: Contribution to journal › Article › peer-review
Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in Macrophages
Research output: Contribution to journal › Article › peer-review
Gene Expression Changes Associated with the Airway Wall Response to Injury
Research output: Contribution to journal › Article › peer-review
The transcriptome of the invasive eel swimbladder nematode parasite Anguillicola crassus
Research output: Contribution to journal › Article › peer-review
When will 'open science' become simply 'science'?
Research output: Contribution to journal › Comment/debate
Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation
Research output: Contribution to journal › Article › peer-review
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
Research output: Contribution to journal › Article › peer-review
C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity
Research output: Contribution to journal › Article › peer-review
Division-induced DNA double strand breaks in the chromosome terminus region of Escherichia coli lacking RecBCD DNA repair enzyme
Research output: Contribution to journal › Article › peer-review
Molecular Longitudinal Tracking of Mycobacterium abscessus spp. during Chronic Infection of the Human Lung
Research output: Contribution to journal › Article › peer-review
A high resolution atlas of gene expression in the domestic sheep (Ovis aries)
Research output: Contribution to journal › Article › peer-review
Caenorhabditis monodelphis sp. n.: defining 1 the stem morphology 2 and genomics of the genus Caenorhabditis
Research output: Contribution to journal › Article › peer-review
Robust statistical modeling improves sensitivity of high-throughput RNA structure probing experiments
Research output: Contribution to journal › Article › peer-review
A molecular palaeobiological exploration of arthropod terrestrialization
Research output: Contribution to journal › Article › peer-review
Escherichia coli- and Staphylococcus aureus - induced mastitis differentially modulate transcriptional responses in neighbouring uninfected bovine mammary gland quarters
Research output: Contribution to journal › Article › peer-review
Frequent, Geographically Structured Heteroplasmy in the Mitochondria of a Flowering Plant, Ribwort Plantain (Plantago lanceolata)
Research output: Contribution to journal › Article › peer-review
11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to western diet
Research output: Contribution to journal › Article › peer-review
Quantitative trait loci mapping for canine hip dysplasia and its related traits in UK Labrador Retrievers
Research output: Contribution to journal › Article › peer-review
Epithelial, metabolic and innate immunity transcriptomic signatures differentiating the rumen from other sheep and mammalian gastrointestinal tract tissues
Research output: Contribution to journal › Article › peer-review
Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity
Research output: Contribution to journal › Article › peer-review
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Research output: Contribution to journal › Article › peer-review
Cross-species inference of long non-coding RNAs greatly expands the ruminant transcriptome
Research output: Contribution to journal › Article › peer-review
Genomic Analysis of DNA Double-Strand Break Repair in Escherichia coli
Research output: Chapter in Book/Report/Conference proceeding › Chapter
1,25-dihydroxyvitamin D3 restrains CD4+ T cell priming ability of CD11c+ dendritic cells by upregulating expression of CD31
Research output: Contribution to journal › Article › peer-review
Exaggerated heterochiasmy in a fish with sex-linked male coloration polymorphisms
Research output: Contribution to journal › Article › peer-review
Lack of long-term acclimation in Antarctic encrusting species suggests vulnerability to warming
Research output: Contribution to journal › Article › peer-review
Genomic associations with bill length and disease reveal drift and selection across island bird populations
Research output: Contribution to journal › Letter › peer-review
Transcriptome analyses of Anguillicola crassus from native and novel hosts
Research output: Contribution to journal › Article › peer-review
Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031
Research output: Contribution to journal › Article › peer-review
Using genome resequencing to investigate racial structure, genetic diversity, sexual reproduction and hybridisation in the pine pathogen Dothistroma septosporum
Research output: Contribution to journal › Article › peer-review
Hfq CLASH uncovers sRNA-target interaction networks linked to nutrient availability adaptation
Research output: Contribution to journal › Article › peer-review
DNA double strand break repair in Escherichia coli perturbs cell division and chromosome dynamics
Research output: Contribution to journal › Article › peer-review
A Conserved TCRβ signature dominates a highly polyclonal T-cell expansion during the acute phase of a murine malaria infection
Research output: Contribution to journal › Article › peer-review
Specific enrichment of hydrocarbonclastic bacteria from diesel-amended soil on biochar particles
Research output: Contribution to journal › Article › peer-review
Epigenetic gene silencing by heterochromatin primes fungal resistance
Research output: Contribution to journal › Article › peer-review
Whole blood profiling of T-cell derived miRNA allows the development of prognostic models in inflammatory bowel disease
Research output: Contribution to journal › Article › peer-review
The mRNA derived MalH sRNA contributes to alternative carbon source utilization by tuning maltoporin expression in E. coli
Research output: Contribution to journal › Article › peer-review