Identification and prediction of coronary artery plaque rupture using 18F-fluoride positron emission tomography

Project: Research

Newby, David (Principal Investigator)

Status	Active
Effective start/end date	1/01/15 → 30/06/22

Total award	£75,104.00
Funding organisation	UK-based charities

Total award	£2,467,421.00
Funding organisation	UK-based charities
Funder project reference	103782/Z/14/Z

Period	1/01/15 → 30/06/22

Research outputs

High-Sensitivity Cardiac Troponin I and Clinical Risk Scores in Patients With Suspected Acute Coronary Syndrome
Research output: Contribution to journal › Article › peer-review
Inhaled Nanoparticles Accumulate at Sites of Vascular Disease
Research output: Contribution to journal › Article › peer-review
Effects of the small molecule SIRT1 activator, SRT2104 on arterial stiffness in otherwise healthy cigarette smokers and subjects with type 2 diabetes mellitus
Research output: Contribution to journal › Article › peer-review
Monitoring the biological activity of abdominal aortic aneurysms Beyond Ultrasound
Research output: Contribution to journal › Article › peer-review
Smooth muscle enriched long non-coding RNA (SMILR) regulates cell proliferation
Research output: Contribution to journal › Article › peer-review
Manganese-enhanced T1 mapping in the myocardium of normal and infarcted hearts.
Research output: Contribution to journal › Article › peer-review
18F-fluoride signal amplification identifies microcalcifications associated with atherosclerotic plaque instability in PET/CT images
Research output: Contribution to journal › Article › peer-review
Myocardial Fibrosis and Cardiac Decompensation in Aortic Stenosis
Research output: Contribution to journal › Article › peer-review
Complementary role of cardiac CT in the assessment of aortic valve replacement dysfunction
Research output: Contribution to journal › Article › peer-review
Computed Tomography and Cardiac Magnetic Resonance in Ischemic Heart Disease
Research output: Contribution to journal › Article › peer-review
A 49-year-old with chest pain and collapse
Research output: Contribution to journal › Article › peer-review
PET Cell Tracking Using 18F-FLT is Not Limited by Local Reuptake of Free Radiotracer
Research output: Contribution to journal › Article › peer-review
End Stage Renal Disease-induced Hypercalcemia May Promote Aortic Valve Calcification via Annexin VI Enrichment of Valve Interstitial Cell Derived-Matrix Vesicles
Research output: Contribution to journal › Article › peer-review
Symptoms and Quality of Life in Patients with Suspected Angina Undergoing Coronary Computed Tomography Angiography
Research output: Contribution to journal › Article › peer-review
Duration of dual antiplatelet therapy in acute coronary syndrome
Research output: Contribution to journal › Article › peer-review
Adverse prognosis associated with asymmetric myocardial thickening in aortic stenosis
Research output: Contribution to journal › Article › peer-review
Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair.
Research output: Contribution to journal › Article › peer-review
Impact of noncardiac findings in patients undergoing CT coronary angiography: a substudy of the Scottish computed tomography of the heart (SCOT-HEART) trial
Research output: Contribution to journal › Article › peer-review
A 59-year-old woman with visible precordial pulsations
Research output: Contribution to journal › Article › peer-review
Comparison of International Guidelines for Assessment of Suspected Stable Angina: Insights From the PROMISE and SCOT-HEART
Research output: Contribution to journal › Article › peer-review
High-Sensitivity Cardiac Troponin I and the Diagnosis of Coronary Artery Disease in Patients With Suspected Angina Pectoris
Research output: Contribution to journal › Article › peer-review
Short-Term Hemodynamic Effects of Apelin in Patients With Pulmonary Arterial Hypertension
Research output: Contribution to journal › Article › peer-review
Breast arterial calcification on mammography and risk of coronary artery disease: A SCOT-HEART sub-study
Research output: Contribution to journal › Article › peer-review
Ticagrelor to reduce myocardial injury in patients with high-risk coronary artery plaque
Research output: Contribution to journal › Article › peer-review
Clinical determinants of plasma cardiac biomarkers in patients with stable chest pain
Research output: Contribution to journal › Article › peer-review
Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis
Research output: Contribution to journal › Article › peer-review
Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice
Research output: Contribution to journal › Article › peer-review
Enhanced monocyte recruitment and delayed alternative macrophage polarization accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice
Research output: Contribution to journal › Article › peer-review
Global burden of atherosclerotic cardiovascular disease in people with hepatitis C virus infection: a systematic review, meta-analysis, and modelling study
Research output: Contribution to journal › Article › peer-review
Manganese-enhanced MRI of the myocardium
Research output: Contribution to journal › Review article › peer-review
Ferumoxytol-enhanced Magnetic Resonance Imaging in Patients with Prior Cardiac Transplantation
Research output: Contribution to journal › Article › peer-review
Standardized reporting systems for computed tomography coronary angiography and calcium scoring: A real-world validation of CAD-RADS and CAC-DRS in patients with stable chest pain
Research output: Contribution to journal › Article › peer-review
Plasma Desmosine and Abdominal Aortic Aneurysm Disease
Research output: Contribution to journal › Article › peer-review
Non-invasive in vivo imaging of acute thrombosis: development of a novel factor XIIIa radiotracer
Research output: Contribution to journal › Article › peer-review
Observer repeatability and interscan reproducibility of 18F-sodium fluoride coronary microcalcification activity
Research output: Contribution to journal › Article › peer-review
Chest pain - when in doubt
Research output: Contribution to journal › Article › peer-review
Validation of European Society of Cardiology pre-test probabilities for obstructive coronary artery disease in suspected stable angina
Research output: Contribution to journal › Article › peer-review
Respiration-averaged CT versus standard CT attenuation maps for correction of the 18F-NaF uptake in hybrid PET/CT
Research output: Contribution to journal › Article › peer-review
Innovation in Medical Imaging To Improve Disease Staging, Therapeutic Intervention, and Clinical Outcomes
Research output: Contribution to journal › Review article › peer-review
We all breathe the same air …. and we are all mortal
Research output: Contribution to journal › Article › peer-review
Eosinophil deficiency promotes aberrant repair and adverse remodelling following acute myocardial infarction
Research output: Contribution to journal › Article › peer-review
Incidence, microbiology and outcomes in patient hospitalized with infective endocarditis
Research output: Contribution to journal › Article › peer-review
Assessment of different quantification metrics of [18F]-NaF PET/CT images of patients with abdominal aortic aneurysm
Research output: Contribution to journal › Article › peer-review
High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome
Research output: Contribution to journal › Article › peer-review
CLINICAL ENDPOINT ADJUDICATION
Research output: Contribution to journal › Comment/debate › peer-review
Coronary 18F-Sodium Fluoride Uptake Predicts Outcomes in Patients With Coronary Artery Disease
Research output: Contribution to journal › Article › peer-review
Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy
Research output: Contribution to journal › Article › peer-review
Quantification of macrophage-driven inflammation during myocardial infarction with 18F-LW223, a novel TSPO radiotracer with binding independent of the rs6971 human polymorphism
Research output: Contribution to journal › Article › peer-review