IST3 (Supplement to R39189) - Third International Stroke Trial (Formerlly MRC G0400069)

Project: Research

Sandercock, Peter (Principal Investigator)
Dennis, Martin (Co-investigator)
Wardlaw, Joanna (Co-investigator)

Status	Finished
Effective start/end date	1/04/10 → 30/09/13

Total award	£2,998,073.00
Funding organisation	Other
Funder project reference	09/800/15

Total award	£345,804.00
Funding organisation	UK-based charities
Funder project reference	09/800/15

Period	1/04/10 → 30/09/13

Research outputs

Visual rating scales of white matter hyperintensities and atrophy: comparison of computed tomography and magnetic resonance imaging
Research output: Contribution to journal › Article
The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial
Research output: Contribution to journal › Article
Third international stroke trial
Research output: Contribution to journal › Article
Alteplase for Acute Ischemic Stroke: Outcomes by Clinically Important Subgroups in the Third International Stroke Trial
Research output: Contribution to journal › Article
Association between brain imaging signs, early and late outcomes, and response to intravenous alteplase after acute ischaemic stroke in the third International Stroke Trial (IST-3): secondary analysis of a randomised controlled trial
Research output: Contribution to journal › Article
Effect of X-Ray Attenuation of Arterial Obstructions on Intravenous Thrombolysis and Outcome after Ischemic Stroke
Research output: Contribution to journal › Article
The NeuroGrid stroke exemplar clinical trial protocol
Research output: Contribution to journal › Article
Uncertainties about thrombolysis for stroke should be addressed with large-scale randomized trials
Research output: Contribution to journal › Article
Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited
Research output: Contribution to journal › Article
Oxfordshire Community Stroke Project Clinical Stroke Syndrome and Appearances of Tissue and Vascular Lesions on Pretreatment CT in Hyperacute Ischemic Stroke Among the First 510 Patients in the Third International Stroke Trial (IST-3)
Research output: Contribution to journal › Article
Effect of alteplase on the CT hyperdense artery sign and functional outcome after ischemic stroke
Research output: Contribution to journal › Article
The third international stroke trial (IST-3) of intravenous thrombolysis with rt-PA: baseline imaging features among 3035 patients randomised
Research output: Contribution to journal › Meeting abstract
Statistical analysis plan for the third International Stroke Trial (IST-3); part of a 'thread' of reports of the trial
Research output: Contribution to journal › Article
Targeting Recombinant Tissue-Type Plasminogen Activator in Acute Ischemic Stroke Based on Risk of Intracranial Hemorrhage or Poor Functional Outcome An Analysis of the Third International Stroke Trial
Research output: Contribution to journal › Article
Sensitivity and specificity of the Hyperdense Artery Sign for arterial obstruction in acute ischemic stroke
Research output: Contribution to journal › Article
The third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke
Research output: Contribution to journal › Article
Effect of intravenous recombinant tissue-type plasminogen activator in patients with mild stroke in the Third International Stroke Trial-3: post hoc analysis
Research output: Contribution to journal › Article
IST-3 stroke trial data available
Research output: Contribution to journal › Letter
Protocol for the perfusion and angiography imaging sub-study of the Third International Stroke Trial (IST-3) of alteplase treatment within six-hours of acute ischemic stroke
Research output: Contribution to journal › Article
Effects of alteplase for acute stroke on the distribution of functional outcomes: a pooled analysis of nine trials
Research output: Contribution to journal › Article
Effect of thrombolysis with alteplase within 6 h of acute ischaemic stroke on long-term outcomes (the third International Stroke Trial [IST-3]): 18-month follow-up of a randomised controlled trial
Research output: Contribution to journal › Article
The third international stroke trial (IST-3) of intravenous rt-PA: effect of age and time on treatment effect among 3035 patients randomised
Research output: Contribution to journal › Meeting abstract
Observer reliability of CT angiography in the assessment of acute ischaemic stroke: data from the Third International Stroke Trial
Research output: Contribution to journal › Article
Observer Agreement on Computed Tomography Perfusion Imaging in Acute Ischemic Stroke
Research output: Contribution to journal › Article