Tissue specific determinants of glucocorticoid signalling in humans - new mechanisms and therapies for cardiovascular risk. (Renewal: YYRS 11-15) - Edinburgh Research Explorer

Edinburgh Research Explorer

Tissue specific determinants of glucocorticoid signalling in humans - new mechanisms and therapies for cardiovascular risk. (Renewal: YYRS 11-15)

Project: Research

Walker, Brian (Principal Investigator)

Status	Finished
Effective start/end date	1/04/11 → 31/03/16

Total award	£1,146,240.00
Funding organisation	UK-based charities
Funder project reference	rg/11/4/28734

Period	1/04/11 → 31/03/16

Research outputs

Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men
Research output: Contribution to journal › Article
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone; a rationale for safer glucocorticoid replacement therapy
Research output: Contribution to journal › Article
Plasma metabolomic profile varies with glucocorticoid dose in patients with congenital adrenal hyperplasia
Research output: Contribution to journal › Article
5α-reduced glucocorticoids exhibit dissociated anti-inflammatory and metabolic effects
Research output: Contribution to journal › Article
Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE)
Research output: Contribution to journal › Article
Systematic review and meta-analysis reveals acutely elevated plasma cortisol following fasting but not less severe calorie restriction
Research output: Contribution to journal › Article
11β-Hydroxysteroid Dehydrogenase Activity in the Brain Does Not Contribute to Systemic Interconversion of Cortisol and Cortisone in Healthy Men
Research output: Contribution to journal › Article