Original language | English |
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Pages (from-to) | 1661-71 |
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Number of pages | 11 |
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Journal | British Journal of Pharmacology |
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Volume | 164 |
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Issue number | 6 |
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DOIs | |
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Publication status | Published - 2011 |
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Dissociating anti-inflammatory efficacy from the metabolic side effects of glucocorticoids is an attractive therapeutic goal. 5α-Tetrahydro-corticosterone (5αTHB), produced from corticosterone by 5α-reductases, activates glucocorticoid receptors. This study compares the effects of 5αTHB on inflammation and metabolism in vitro and in vivo.
ID: 3114051