Edinburgh Research Explorer

A highly selective fluorogenic probe for the detection and in vivo imaging of Cu/Zn superoxide dismutase

Research output: Contribution to journalArticle

Related Edinburgh Organisations

Open Access permissions

Open

Documents

  • Download as Adobe PDF

    Rights statement: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence

    Final published version, 3 MB, PDF document

    Licence: Creative Commons: Attribution (CC-BY)

Original languageEnglish
JournalChemical Communications
DOIs
Publication statusPublished - 4 Mar 2016

Abstract

Copper/zinc superoxide dismutase (Cu/Zn SOD) is an essential enzyme that protects tissue from oxidative damage. Herein we report the first fluorogenic probe (SODO) for the detection and in vivo imaging of Cu/Zn SOD. SODO represents a unique chemical probe for translational imaging studies of Cu/Zn SOD in inflammatory disorders.

Download statistics

No data available

ID: 24458613