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A Trp-BODIPY cyclic peptide for fluorescence labelling of apoptotic bodies

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Original languageEnglish
JournalChemical Communications
Early online date15 Dec 2016
Publication statusE-pub ahead of print - 15 Dec 2016


The rational design and synthesis of a Trp-BODIPY cyclic peptide for the fluorescent labelling of apoptotic bodies is described. Affinity assays, confocal microscopy and flow cytometry analysis confirmed the binding of the peptide to negatively-charged
phospholipids associated with apoptosis, and its applicability for the detection and characterisation of subcellular structures released by apoptotic cells

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ID: 29655351