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A virus-neutralising monoclonal antibody expressed in the milk of transgenic mice

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Original languageEnglish
Pages (from-to)411-4
Number of pages4
JournalAdvances in Experimental Medicine and Biology
Volume494
DOIs
Publication statusPublished - 2001

Abstract

Coronaviruses are frequently associated with respiratory and gastrointestinal disorders in both animals and man. In adult animals, Coronavirus infections are generally mild, however, in neonates they often cause severe and sometimes lethal diseases (Enjuanes and van der Zeijst, 1995). Maternal antibodies supplied via the placenta and milk efficiently protect new-born animals against the fatal consequences of acute coronaviral infections during this critical phase (Hornberger, 1992).

    Research areas

  • Animals, Antibodies, Monoclonal, Antibodies, Viral, Coronavirus Infections, Female, Mice, Mice, Transgenic, Milk, Murine hepatitis virus, Neutralization Tests, Recombinant Proteins

ID: 8781465