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Acoustic Assessment of a Konjac–Carrageenan Tissue-Mimicking Material at 5–60 MHz

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Original languageEnglish
Pages (from-to)2895-2902
Number of pages8
JournalUltrasound in Medicine & Biology
Issue number12
Early online date20 Oct 2014
Publication statusPublished - Dec 2014


The acoustic properties of a robust tissue-mimicking material based on konjac–carrageenan at ultrasound frequencies in the range 5–60 MHz are described. Acoustic properties were characterized using two methods: a broadband reflection substitution technique using a commercially available preclinical ultrasound scanner (Vevo 770, FUJIFILM VisualSonics, Toronto, ON, Canada), and a dedicated high-frequency ultrasound facility developed at the National Physical Laboratory (NPL, Teddington, UK), which employed a broadband through-transmission substitution technique. The mean speed of sound across the measured frequencies was found to be 1551.7 ± 12.7 and 1547.7 ± 3.3 m s−1, respectively. The attenuation exhibited a non-linear dependence on frequency, f (MHz), in the form of a polynomial function: 0.009787f2 + 0.2671f and 0.01024f2 + 0.3639f, respectively. The characterization of this tissue-mimicking material will provide reference data for designing phantoms for preclinical systems, which may, in certain applications such as flow phantoms, require a physically more robust tissue-mimicking material than is currently available.

    Research areas

  • Ultrasound, High frequency, Tissue-mimicking material, Speed of sound, Attenuation, Preclinical ultrasound, DOPPLER ULTRASOUND, FLOW PHANTOMS, BLOOD-FLOW, FREQUENCY, ATTENUATION, SPEED, VELOCITY, VALIDATION, SOUND, ARRAY

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