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Acute in vivo regulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by insulin and intralipid infusions in humans

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)4682-8
Number of pages7
JournalJournal of Clinical Endocrinology & Metabolism
Issue number11
Publication statusPublished - 2006


Extraadrenal regeneration of cortisol by 11beta-hydroxysteroid dehydrogenase type 1 (11HSD1) is increased after a mixed meal. It is unknown which tissue is responsible and whether this reflects the complex transcriptional control of 11HSD1 or posttranscriptional control exerted by supply of reduced nicotinamide adenine dinucleotide phosphate from hexose-6-phosphate dehydrogenase.

ID: 3115385