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Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct

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Original languageEnglish
JournalDiabetes Obesity & Metabolism
Early online date8 Feb 2017
DOIs
StateE-pub ahead of print - 8 Feb 2017

Abstract

Glucocorticoid excess causes obesity and diabetes, in this new work we have discovered that glucocorticoids do not directly alter glucose appearance or uptake or the breakdown of fat tissue in humans, but instead mediate these effects through key interactions with the other critical hormones insulin and adrenaline in humans.

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