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Caging and uncaging genetics

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Original languageEnglish
JournalPLoS Biology
Issue number7
Publication statusPublished - 26 Jul 2016


It is important for biology to understand if observations made in highly reductionist laboratory settings generalise to harsh and noisy natural environments where genetic variation is sorted to produce adaptation. But what do we learn by studying, in the laboratory, a genetically diverse population that mirrors the wild? What is the best design for studying genetic variation? When should we consider it at all? The right experimental approach depends on what you want to know.

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