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Cardiovascular effects of particulate air pollution exposure: time course and underlying mechanisms

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Original languageEnglish
Pages (from-to)224-239
Number of pages16
JournalJournal of Internal Medicine
Volume272
Issue number3
DOIs
Publication statusPublished - Sep 2012

Abstract

Objective Air pollution is now recognized as an important independent risk factor for cardiovascular morbidity and mortality and may be responsible for up to 3 similar to million premature deaths each year worldwide. The mechanisms underlying the observed effects are poorly understood but are likely to be multifactorial. Here, we review the acute and chronic effects of air pollution exposure on the cardiovascular system and discuss how these effects may explain the observed increases in cardiovascular morbidity and mortality.

    Research areas

  • HARVARD 6 CITIES, HEALTHY-HUMAN VOLUNTEERS, AUTONOMIC NERVOUS-SYSTEM, vascular function, atherosclerosis, OBSTRUCTIVE PULMONARY-DISEASE, air pollution, cardiovascular disease, HEART-RATE-VARIABILITY, EXTENDED FOLLOW-UP, CORONARY-ARTERY-DISEASE, thrombosis, DIESEL-EXHAUST INHALATION, ST-SEGMENT DEPRESSION, LONG-TERM EXPOSURE

ID: 7909296