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Changes in forced expiratory volume in 1 second over time in COPD

Research output: Contribution to journalArticle

  • Jørgen Vestbo
  • Lisa D Edwards
  • Paul D Scanlon
  • Julie C Yates
  • Alvar Agusti
  • Per Bakke
  • Peter M A Calverley
  • Bartolome Celli
  • Harvey O Coxson
  • Courtney Crim
  • David A Lomas
  • William MacNee
  • Bruce E Miller
  • Edwin K Silverman
  • Ruth Tal-Singer
  • Emiel Wouters
  • Stephen I Rennard
  • ECLIPSE Investigators

Related Edinburgh Organisations

Original languageEnglish
Pages (from-to)1184-92
Number of pages9
JournalNew England Journal of Medicine
Issue number13
Publication statusPublished - 2011


A key feature of chronic obstructive pulmonary disease (COPD) is an accelerated rate of decline in forced expiratory volume in 1 second (FEV(1)), but data on the variability and determinants of this change in patients who have established disease are scarce.

ID: 3545355