Edinburgh Research Explorer

Childhood body weight in relation to morbidity from cardiovascular disease and cancer in older adulthood: 67-year follow-up of participants in the 1947 Scottish Mental Survey

Research output: Contribution to journalArticle

Related Edinburgh Organisations

Open Access permissions

Open

Documents

Original languageEnglish
Pages (from-to)775-80
Number of pages6
JournalAmerican Journal of Epidemiology
Volume182
Issue number9
Early online date6 Oct 2015
DOIs
Publication statusPublished - 1 Nov 2015

Abstract

Although it has been well documented that elevated body weight in middle- and older-aged populations is associated with multiple morbidities, the influence of childhood body weight on health endpoints other than coronary heart disease is not well understood. Accordingly, using a subsample of 4,620 participants (2,288 women) from the Scottish Mental Survey of 1947, we examined the association between body mass index measured at 11 years of age and future risk of 9 independent health endpoints as ascertained from national hospital admissions and cancer registers until 2014 (up to age 77 years). Although there was some evidence of a relationship between elevated childhood body mass index and higher rates of peripheral vascular disease (per each 1-standard deviation increase in body mass index, hazard ratio = 1.21, 95% confidence interval: 1.07, 1.37) and smoking-related cancers (per each 1-standard deviation increase in body mass index, hazard ratio = 1.09, 95% confidence interval: 1.01, 1.17), there was no apparent association with coronary heart disease, stroke (including ischemic stroke), heart failure, or carcinomas of the colorectum, stomach, lung, prostate, or breast. In conclusion, a relationship between childhood body weight and later morbidity was largely lacking in the present study.

    Research areas

  • Aged, Aged, 80 and over, Body Mass Index, Body Weight, Cardiovascular Diseases, Child, Child, Preschool, Female, Humans, Male, Neoplasms, Pediatric Obesity, Scotland, Surveys and Questionnaires

Download statistics

No data available

ID: 25071917