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CT features of feline lipiduria and renal cortical lipid deposition

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Original languageEnglish
JournalJournal of Feline Medicine and Surgery
Early online date22 Sep 2020
Publication statusE-pub ahead of print - 22 Sep 2020


Objectives The aims of this study were to document the presence and prevalence of feline lipiduria and renal lipid deposition on CT, and to search for associations between the presence of lipiduria and sex, urinary tract abnormalities and urolithiasis. Methods The CT examinations of 252 cats were reviewed for the presence of an antigravitational hypodense bubble in the urinary bladder with density values between −180 Hounsfield units (HU) and −20HU. To identify associations between lipiduria and sex, urinary tract abnormalities and urolithiasis, Fisher’s exact test was used. Renal cortical density measurement was performed in all cats. The Mann−Whitney test was performed to compare renal cortical density between lipiduric and unaffected cats. Results A total of 27 domestic cats (10.7%) had CT evidence of lipiduria. Lipiduric cats had a significantly lower renal cortical density than unaffected cats (P <0.01). Male neutered cats had a significantly higher frequency of lipiduria and lower renal cortical density compared with female neutered cats (P <0.01). There was no significant difference between the groups regarding renal, ureteral or urethral abnormalities. Conclusions and relevance Lipiduria is a common physiological phenomenon in cats that can be detected on routine CT examinations. Decreased renal cortical density is associated with lipiduria. This may aid in the diagnosis of feline lipiduria and help to differentiate its presence from other pathological depositions and excretions.

    Research areas

  • CT, Fat droplets, Lipiduria, Fat-fluid level

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