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Cytological and microbiological characteristics of middle ear effusions in brachycephalic dogs.

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  • Cytological and microbiological characteristics of middle ear effusions in brachycephalic dogs

    Rights statement: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in anymedium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.© 2020 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine

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    Licence: Creative Commons: Attribution-NonCommercial-NoDerivatives (CC BY-NC-ND)

Original languageEnglish
Pages (from-to)1454–1463
Number of pages9
JournalJournal of Veterinary Internal Medicine
Early online date14 May 2020
Publication statusPublished - 24 Jul 2020


Background: Middle ear effusion is common in brachycephalic dogs with similarities to otitis media with effusion in children. Association with cranial and Eustachian tube morphology and bacterial infection is suspected in both species.
Hypothesis/objectives: To determine cytological and bacteriological features of middle ear effusions in dogs, provide information on histological features and further assess the dog as a model of the human disease.
Animals: Sixteen live dogs, three post mortem cases of middle ear effusion, and two post mortem controls.
Methods: Prospective; clinical investigation using CT, MRI, video-otoscopy, myringotomy; cytological assessment of 30 and bacteriology of 28 effusions; histology and immunohistochemistry (CD3 for T-lymphocytes, Pax5 for B-lymphocytes and MAC387 for macrophages) of 10 middle ear sections.

    Research areas

  • Canine, Cavalier King Charles spaniel, Immunohistochemistry, Middle ear, Otitis Media With Effusion

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