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Differential chemosensitivity of tumor components in a malignant oligodendroglioma: assessment with diffusion-weighted, perfusion-weighted, and serial volumetric MR imaging

Research output: Contribution to journalArticle

  • Hans Rolf Jäger
  • Adam D Waldman
  • Christopher Benton
  • Nicholas Fox
  • Jeremy Rees

Related Edinburgh Organisations

Original languageEnglish
Pages (from-to)274-8
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume26
Issue number2
Publication statusPublished - Feb 2005

Abstract

We report the case of malignant oligodendroglioma in a 36-year-old man who underwent diffusion-weighted, perfusion-weighted, and volumetric MR imaging before and after PCV (procarbazine, CCNU, vincristine) chemotherapy. The tumor regions exhibiting a low apparent diffusion coefficient and increased relative cerebral blood volume showed a marked response to chemotherapy and dramatic decrease in volume, whereas the remaining tumor regions showed little change. Diffusion-weighted and perfusion-weighted MR imaging may be helpful in predicting chemosensitivity of glial tumors.

    Research areas

  • Adult, Diffusion Magnetic Resonance Imaging, Humans, Magnetic Resonance Imaging, Male, Oligodendroglioma, Case Reports, Journal Article

ID: 46191254