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DNA methylation as a genomic marker of exposure to chemical and environmental agents.

Research output: Contribution to journalReview article

Original languageEnglish
JournalCurrent opinion in chemical biology
Volume45
Early online date2 Mar 2018
DOIs
Publication statusPublished - Aug 2018

Abstract

Recent progress in interpreting comprehensive genetic and epigenetic profiles
for human cellular states has contributed new insights into the developmental
origins of disease, elucidated novel signalling pathways and enhanced drug
discovery programs. A similar comprehensive approach to decoding the
epigenetic readouts from chemical challenges in vivo would yield new
paradigms for monitoring and assessing environmental exposure in model
systems and humans.

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