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Does age affect medial prefrontal functions? A behavioral investigation

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    Rights statement: ©American Psychological Association, [Year]. This paper is not the copy of record and may not exactly replicate the authoritative document published in the APA journal. Please do not copy or cite without author's permission. The final article is available, upon publication, at: [ARTICLE DOI]"

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Original languageEnglish
JournalPsychology & Neuroscience
Publication statusAccepted/In press - 22 Nov 2019


The aging process has been shown to impair cognitive functions subsumed by the frontal lobes, but this region is heterogeneous and functions can be subdivided into different categories. Previous research focuses on aging within functions associated with dorsolateral and orbital prefrontal regions. This study investigates functions associated with another region – the medial prefrontal cortex. Tasks which tap abilities associated with dorsolateral and orbital prefrontal regions were administered to older and younger adults to replicate previous observations. Additionally, tasks which tap medial prefrontal abilities were administered, and age effects examined. Age-related differences were found on dorsolateral but not orbital prefrontal abilities. Significant age effects were also observed on both medial prefrontal tasks. These preliminary results support a region-specific theory of cognitive aging whereby dorsolateral and medial functions are most susceptible to decline, with orbital prefrontal functions remaining relatively preserved.

    Research areas

  • medial prefrontal functions, frontal lobes, aging, AX-Continuous Performance Task, Simon Task

ID: 122024752