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Encoded peptide libraries and the discovery of new cell binding ligands

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Original languageEnglish
Pages (from-to)7638-7640
Number of pages3
JournalChemical Communications
Volume47
Issue number27
DOIs
Publication statusPublished - 2011

Abstract

Cells over-expressing integrins or CCR6 were incubated on a DNA microarray, pre-hybridized with a 10 000 member PNA-encoded peptide library allowing novel cell specific ligands for integrins and CCR6 to be identified.

    Research areas

  • NUCLEIC-ACID, MICROARRAYS, INTEGRIN, IDENTIFICATION, PNA, ADHESION, RECEPTOR, IMMOBILIZATION, STABILITY, SELECTION

ID: 1478049