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Estimating the location and size of retinal injections from orthogonal images of an intact retina

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http://bmcneurosci.biomedcentral.com/articles/10.1186/s12868-015-0217-8
Original languageEnglish
Pages (from-to)1-10
Number of pages10
JournalBMC Neuroscience
Volume16
Issue number1
DOIs
Publication statusPublished - 21 Nov 2015

Abstract

To study the mapping from the retina to the brain, typically a small region of the retina is injected with a dye, which then propagates to the retina's target structures. To determine the location of the injection, usually the retina is dissected out of the eye, flattened and then imaged, causing tears and stretching of the retina. The location of the injection is then estimated from the image of the flattened retina. Here we propose a new method that avoids dissection of the retina.

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