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Estimating white matter tract volume in partial volume voxels with diffusion MRI

Research output: Contribution to conferencePosterpeer-review

Original languageEnglish
Publication statusPublished - 2009
EventISMRM 17th Scientific Meeting and Exhibition - Honolulu, United States
Duration: 18 Apr 200924 Apr 2009


ConferenceISMRM 17th Scientific Meeting and Exhibition
CountryUnited States


Diffusion MRI (dMRI) is the only method that allows in vivo segmentation of white matter (WM) fasciculi and assessment of their integrity, based on the water diffusion anisotropy caused by highly ordered bundles of axons. It can therefore be used to study wm decline: loss of integrity and tract thinning. Their disambiguation given the MRI data is not trivial. We show that it is possible to obtain reasonable estimates of both tract volume (on a sub-voxel level) and diffusivity parameters linked to the well being of axonal bundles using a plausible spatial coherence assumption.


ISMRM 17th Scientific Meeting and Exhibition


Honolulu, United States

Event: Conference

ID: 18505801