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Facilitating functional annotation of chicken microarray data

Research output: Contribution to journalArticle

  • Teresia J Buza
  • Ranjit Kumar
  • Cathy R Gresham
  • Shane C Burgess
  • Fiona M McCarthy

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    Rights statement: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Original languageEnglish
Pages (from-to)S2
JournalBMC Bioinformatics
Volume10 Suppl 11
DOIs
Publication statusPublished - 2009

Abstract

Modeling results from chicken microarray studies is challenging for researchers due to little functional annotation associated with these arrays. The Affymetrix GenChip chicken genome array, one of the biggest arrays that serve as a key research tool for the study of chicken functional genomics, is among the few arrays that link gene products to Gene Ontology (GO). However the GO annotation data presented by Affymetrix is incomplete, for example, they do not show references linked to manually annotated functions. In addition, there is no tool that facilitates microarray researchers to directly retrieve functional annotations for their datasets from the annotated arrays. This costs researchers amount of time in searching multiple GO databases for functional information.

    Research areas

  • Animals, Chickens, Databases, Genetic, Genome, Genomics, Oligonucleotide Array Sequence Analysis

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