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Feasibility of hair sampling to assess levels of organophosphate metabolites in rural areas of Sri Lanka

Research output: Contribution to journalArticle

  • D. W. Knipe
  • C. Jayasumana
  • S. Siribaddana
  • C. Priyadarshana
  • M. Pearson
  • D. Gunnell
  • C. Metcalfe
  • M. N. Tzatzarakis
  • A. M. Tsatsakis

Related Edinburgh Organisations

Original languageEnglish
Pages (from-to)207-211
Number of pages5
JournalEnvironmental Research
Volume147
DOIs
Publication statusPublished - 1 May 2016

Abstract

Measuring chronic pesticide exposure is important in order to investigate the associated health effects. Traditional biological samples (blood/urine) are difficult to collect, store and transport in large epidemiological studies in settings such as rural Asia. We assessed the acceptability of collecting hair samples from a rural Sri Lankan population and found that this method of data collection was feasible. We also assessed the level of non-specific metabolites (DAPS) of organophosphate pesticides in the hair samples. The median concentration (pg/mg) of each DAP was: diethyl phosphate: 83.3 (IQI 56.0, 209.4); diethyl thiophosphate: 34.7 (IQI 13.8, 147.9); diethyl dithiophosphate: 34.5 (IQI 23.4, 55.2); and dimethyl phosphate: 3 (IQI 3, 109.7). Total diethylphosphates were recovered in >80% of samples and were positively correlated with self-reported pesticide exposure.

    Research areas

  • Chronic exposure, Dialkylphosphates metabolites, Hair, Pesticides, Sri Lanka

ID: 41312196