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High-Density Polymer Microarrays: Identifying Synthetic Polymers that Control Human Embryonic Stem Cell Growth

Research output: Contribution to journalArticle

Original languageEnglish
Pages (from-to)848-853
Number of pages6
JournalAdvanced healthcare materials
Volume3
Issue number6
DOIs
Publication statusPublished - Jun 2014

Abstract

The fabrication of high-density polymer microarray is described, allowing the simultaneous and efficient evaluation of more than 7000 different polymers in a single-cellular-based screen. These high-density polymer arrays are applied in the search for synthetic substrates for hESCs culture. Up-scaling of the identified hit polymers enables long-term cellular cultivation and promoted successful stem-cell maintenance.

    Research areas

  • SELF-RENEWAL, BIOMATERIALS, CULTURE, PLURIPOTENCY, HYDROGELS, THERAPY, DISEASE, LINES

ID: 16777522