Research output: Contribution to journal › Article › peer-review
Original language | English |
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Pages (from-to) | 2439-2441 |
Number of pages | 3 |
Journal | IEEE Transactions on Magnetics |
Volume | 43 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2007 |
A novel magnetic encoding technique for performing high-throughput biological assays using molecular probes such as antibodies and DNA oligonucleotides is presented. Electrodeposited Ni/Au multilayer pillar structures with diameters from 5-20 mu m and thicknesses from 1-10 mu m are presented as "magnetic barcodes," where the number of unique codes possible increases exponentially with a linear increase in pillar size. We have successfully functionalized these pillars using a HS-C-10-NHS self-assembled monolayer (SAM) grown on the An cap layer and attachment of an NH2 modified primer oligo sequence and have shown hybridization and denaturation to a fluorescent template. In addition we have developed a novel release layer methodology that allows a large library of probes to be inkjet printed on a single 5 mm(2) chip prior to release.
ID: 1513014